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Nature, ISSN 0028-0836, 10/2015, Volume 526, Issue 7571, pp. 50 - 51
The mechanism by which UBE3A activity is regulated in the brain has been poorly understood. Writing in Cell, Yi et al.5 report that phosphorylation dynamically... 
Autism | Diagnosis | Proteins | Enzymes | Phosphorylation | Neurons | Mutation | Kinases | Molecular biology
Journal Article
Journal Article
Neuron, ISSN 0896-6273, 2002, Volume 36, Issue 3, pp. 493 - 505
Journal Article
Journal of clinical investigation, ISSN 0021-9738, 2015, Volume 125, Issue 5, pp. 2069 - 2076
Angelman syndrome (AS) is a severe neurodevelopmental disorder that results from loss of function of the maternal ubiquitin protein ligase E3A (UBE3A) allele.... 
MEDICINE, RESEARCH & EXPERIMENTAL | MEMORY | MOUSE MODEL | MICE | PHENOTYPES | LONG-TERM POTENTIATION | INHIBITORS | MUTATIONS | DEFICITS | DISC1 | REVERSAL | Genomic Imprinting | Age Factors | Male | Epilepsy - physiopathology | Ubiquitin-Protein Ligases - physiology | Angelman Syndrome - therapy | Cerebral Cortex - physiopathology | Cerebellum - embryology | Anxiety - therapy | Gene Expression Regulation, Developmental | Angelman Syndrome - genetics | Epilepsy - genetics | Female | Disease Models, Animal | Recombinant Fusion Proteins - biosynthesis | Stereotyped Behavior - physiology | Hippocampus - embryology | Genes, Synthetic | Anxiety - physiopathology | Cerebellum - physiopathology | Ubiquitin-Protein Ligases - biosynthesis | Anxiety - genetics | Phenotype | Animals | Movement Disorders - physiopathology | Cerebral Cortex - embryology | Movement Disorders - therapy | Neuronal Plasticity | Angelman Syndrome - embryology | Tamoxifen - pharmacology | Recombinant Fusion Proteins - genetics | Ubiquitin-Protein Ligases - deficiency | Angelman Syndrome - physiopathology | Mice | Movement Disorders - genetics | Ubiquitin-Protein Ligases - genetics | Hippocampus - physiopathology | Epilepsy - therapy | Physiological aspects | Research | Ligases | Genes | Proteins | Studies | Software | Behavior | Gene expression | Epilepsy | Development | Genetics | Neuroscience
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1052 - 12
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 03/2016, Volume 21, Issue 3, pp. 364 - 375
Journal Article
Journal Article
Journal Article
Neuron, ISSN 0896-6273, 2010, Volume 67, Issue 4, pp. 618 - 628
Journal Article