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Journal Article
Journal of Cell Science, ISSN 0021-9533, 03/2007, Volume 120, Issue 5, pp. 815 - 825
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 08/2008, Volume 295, Issue 2, pp. 378 - 387
We have previously shown that Rho small GTPase is required for modulating both cell migration and proliferation through cytoskeleton reorganization and focal... 
Cell proliferation | Cell-cell junctions | Corneal epithelial cells | Cell-matrix adhesion | Cell migration | PHYSIOLOGY | BINDING PROTEIN-RHO | cell proliferation | SERINE-THREONINE KINASE | PUTATIVE TARGET | MYOSIN-II | CELL BIOLOGY | SIGNAL-TRANSDUCTION | GROWTH-FACTOR RECEPTOR | ACTIN STRESS FIBERS | corneal epithelial cells | cell-cell junctions | SMALL GTPASE RHO | cell-matrix adhesion | ENDOTHELIAL-CELLS | cell migration | SERINE/THREONINE KINASE | Epithelial Cells - metabolism | Cadherins - metabolism | Gene Expression - drug effects | Epithelium, Corneal - cytology | Epithelial Cells - drug effects | Humans | Stress, Mechanical | Extracellular Signal-Regulated MAP Kinases - metabolism | Wound Healing | Adherens Junctions - metabolism | Epithelium, Corneal - physiology | rho-Associated Kinases - antagonists & inhibitors | Occludin | Tight Junctions - physiology | rho-Associated Kinases - metabolism | Myosin-Light-Chain Phosphatase - metabolism | Lysophospholipids - pharmacology | Membrane Proteins - metabolism | Phosphorylation - drug effects | Epithelial Cells - cytology | Tight Junctions - drug effects | Amides - pharmacology | Enzyme Inhibitors - pharmacology | rho-Associated Kinases - genetics | Cell Adhesion - drug effects | Reverse Transcriptase Polymerase Chain Reaction | beta Catenin - metabolism | Blotting, Western | Cell Movement - drug effects | Heparin-binding EGF-like Growth Factor | Intercellular Signaling Peptides and Proteins - pharmacology | Adherens Junctions - drug effects | Epithelium, Corneal - metabolism | Cell Proliferation - drug effects | Pyridines - pharmacology | Cell Line, Transformed | Protein and Vesicle Trafficking, Cytoskeleton
Journal Article
Diabetes, ISSN 0012-1797, 06/2018, Volume 67, Issue 6, pp. 1162 - 1172
EPHX2 (encoding soluble epoxide hydrolase [sEH]) converts biologically active epoxyeicosatrienoic acids (EETs), anti-inflammatory and profibrinolytic... 
IN-VITRO | HYPERGLYCEMIA | INFLAMMATION | DISEASE | TISSUE | ENDOCRINOLOGY & METABOLISM | INJURY | EPOXYEICOSATRIENOIC ACIDS | EXPRESSION | DELETION | EPOXYEICOSANOIDS | Retina - drug effects | Gene Expression Regulation, Enzymologic - drug effects | Neurons - pathology | Heme Oxygenase-1 - metabolism | Humans | Middle Aged | Cataract - pathology | Cornea - physiology | Male | Diabetes Mellitus, Type 1 - complications | Diabetic Retinopathy - pathology | Heme Oxygenase-1 - genetics | Cornea - drug effects | Neurons - physiology | Female | Cornea - pathology | Membrane Proteins - metabolism | Neurons - drug effects | Wound Healing - drug effects | Diabetes Mellitus, Type 2 - complications | Membrane Proteins - genetics | Mice, Inbred C57BL | Nerve Tissue Proteins - agonists | Eye Banks | Cataract - metabolism | Membrane Proteins - agonists | Nerve Tissue Proteins - genetics | Diabetic Retinopathy - metabolism | Epoxide Hydrolases - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Retina - physiology | Cataract - complications | Animals | Nerve Regeneration - drug effects | Cornea - innervation | Epoxide Hydrolases - metabolism | Cataract - drug therapy | Protoporphyrins - therapeutic use | Debridement - adverse effects | Retina - pathology | Enzymes | Care and treatment | Messenger RNA | Corneal diseases | Hydrolases | Research | Diabetes | Risk factors | 0101 | Complications
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, p. e32128
Connective Tissue Growth Factor (CTGF) and Transforming growth factor-beta 1 (TGF-beta 1) are key growth factors in regulating corneal scarring. Although CTGF... 
MATRIX CONTRACTION | FACTOR-BETA | EPITHELIAL-CELLS | PATHWAY | MAP KINASE | MULTIDISCIPLINARY SCIENCES | N-TERMINAL KINASE | MESANGIAL CELLS | SMOOTH-MUSCLE-CELLS | FIBROBLASTS | CTGF | Eye Injuries, Penetrating - pathology | Rats, Wistar | Cornea - enzymology | Humans | JNK Mitogen-Activated Protein Kinases - metabolism | Male | Cornea - drug effects | Connective Tissue Growth Factor - secretion | Telomerase - metabolism | Cornea - pathology | Flavonoids - pharmacology | Phosphorylation - drug effects | Corneal Stroma - enzymology | Wound Healing - drug effects | Transforming Growth Factor beta1 - pharmacology | Corneal Stroma - drug effects | Collagen Type I - metabolism | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Rats | Imidazoles - pharmacology | Enzyme Activation - drug effects | Fibroblasts - pathology | Anthracenes - pharmacology | Fibronectins - metabolism | Gene Expression Regulation - drug effects | Animals | MAP Kinase Signaling System - drug effects | Fibroblasts - drug effects | Corneal Stroma - pathology | Cicatrix - enzymology | Cicatrix - pathology | Connective Tissue Growth Factor - genetics | Pyridines - pharmacology | Cell Line, Transformed | Connective Tissue Growth Factor - metabolism | Eye Injuries, Penetrating - enzymology | Fibronectins | Care and treatment | Wound healing | Collagen | Analysis | Bone morphogenetic proteins | Transforming growth factors | Telomerase | Wounds and injuries | Cornea | Transcription factors | Collagen (type I) | Phosphorylation | Pathogenesis | Transforming growth factor | Smooth muscle | Kinases | Fibronectin | Cell adhesion & migration | Proteins | Connective tissues | Signal transduction | Fibroblasts | Inhibition | Growth factors | Stroma | c-Jun protein | MAP kinase | Connective tissue growth factor | Signaling | Scars | Inhibitors | Healing
Journal Article
European Journal of Immunology, ISSN 0014-2980, 09/2014, Volume 44, Issue 9, pp. 2667 - 2679
We previously showed that topical flagellin induces profound mucosal innate protection in the cornea against microbial infection, a response involving multiple... 
CXCL10 | Innate immunity | Fungal keratitis | Natural killer cells | Antimicrobial peptides | Cxcl10 | CHEMOKINES | IMMUNOLOGY | DEFICIENCY | REPAIR | FUSARIUM-KERATITIS | PROTECTIVE ROLE | CXCR3 | ANTIMICROBIAL PEPTIDE | MICE | INFLAMMATORY RESPONSE | T-CELLS | Candidiasis - genetics | Immunity, Mucosal - immunology | Keratitis - immunology | Keratitis - pathology | Keratitis - microbiology | Cornea - immunology | Homeodomain Proteins - immunology | Killer Cells, Natural - pathology | Flagellin - pharmacology | Immunity, Mucosal - drug effects | Chemokine CXCL10 - immunology | Flagellin - chemistry | Killer Cells, Natural - immunology | Cornea - pathology | Candidiasis - immunology | Immunity, Mucosal - genetics | Cornea - microbiology | Keratitis - genetics | Flagellin - immunology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Candida albicans - immunology | Flagellin - isolation & purification | Homeodomain Proteins - genetics | Mice, Knockout | Gene Expression Regulation - drug effects | Pseudomonas aeruginosa - chemistry | Animals | Chemokine CXCL10 - genetics | Receptors, CXCR3 - genetics | Candidiasis - therapy | Receptors, CXCR3 - immunology | Mice | Immunity, Cellular | Keratitis - therapy | Employee recruitment | Killer cells | Peptides | Analysis | Genetic research | T cells | Health aspects | Medical research | Infections | innate immunity | antimicrobial peptides
Journal Article