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Journal Article
OncoImmunology, ISSN 2162-4011, 08/2012, Volume 1, Issue 5, pp. 630 - 641
Tobacco smoke-induced accelerated cell senescence has been implicated in the pathogenesis of chronic obstructive pulmonary disease (COPD). Cell senescence is... 
senescence | autophagy | p62 | ubiquitin | COPD | Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Ubiquitin | Senescence | Autophagy | P62 | ONCOLOGY | CIGARETTE-SMOKE | IMMUNOLOGY | Research Paper
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 03/2012, Volume 46, Issue 3, pp. 306 - 312
Cigarette smoke induces damage to proteins and organelles by oxidative stress, resulting in accelerated epithelial cell senescence in the lung, which is... 
Bronchial epithelial cells | Cell senescence | Chronic obstructive pulmonary disease | Creatine kinase B | LUNG | PROTEIN | bronchial epithelial cells | BIOCHEMISTRY & MOLECULAR BIOLOGY | ISOENZYMES | CELL BIOLOGY | SKELETAL-MUSCLE | OBSTRUCTIVE PULMONARY-DISEASE | INHIBITION | OXIDATIVE MODIFICATION | RESPIRATORY SYSTEM | CXCR2 | creatine kinase B | EXPRESSION | cell senescence | chronic obstructive pulmonary disease | COPD | Immunohistochemistry | Smoking - adverse effects | Bronchi - enzymology | Epithelial Cells - drug effects | Humans | Cellular Senescence - drug effects | Cyclin B1 - metabolism | Bronchi - immunology | Protein Carbonylation - drug effects | Bronchi - drug effects | Protease Inhibitors - pharmacology | Ubiquitination | RNA Interference | beta-Galactosidase - metabolism | Interleukin-8 - metabolism | Bronchi - pathology | Enzyme-Linked Immunosorbent Assay | Smoke - adverse effects | Down-Regulation | Cells, Cultured | Creatine Kinase, BB Form - antagonists & inhibitors | Epithelial Cells - pathology | Creatine Kinase, BB Form - metabolism | Creatine Kinase, BB Form - genetics | Signal Transduction - drug effects | Epithelial Cells - immunology | Epithelial Cells - enzymology | Protein Kinase Inhibitors - pharmacology | Oxidative Stress - drug effects | Proteasome Endopeptidase Complex - metabolism | Proteasome Inhibitors
Journal Article
Journal of Immunology, ISSN 0022-1767, 02/2014, Volume 192, Issue 3, pp. 958 - 968
Journal Article
Journal Article
by Kajimoto, Katsuya and Minami, Yuichiro and Otsubo, Shigeru and Sato, Yukihito and Sato, Takatoshi and Sato, Takamasa and Sato, Naoki and Asai, Kuniya and Munakata, Ryo and Aokage, Toshiyuki and Yoshida, Asuka and Yoshida, Daisuke and Yoshida, Kentaro and Yumino, Dai and Mizuno, Kiyo-o and Mizuno, Masayuki and Kawada, Erisa and Ozaki, Yuri and Kogure, Tomohito and Haruki, Shintaro and Nakao, Koichi and Sawamura, Tadashi and Sawamura, Akinori and Nuki, Toshiaki and Ishiki, Ryoji and Yokota, Yuya and Yokota, Shigeki and Fujinaga, Hiroyuki and Yamamoto, Takashi and Harada, Kenji and Saito, Taro and Saito, Akihiro and Kageyama, Norihito and Okumura, Takanobu and Hata, Noritake and Murai, Koji and Nozaki, Ayaka and Kawanaka, Hidekazu and Tanabe, Jun and Ishii, Katsuhisa and Oiwa, Hitoshi and Matsumoto, Tomoaki and Kato, Hiromasa and Kato, Nobuo and Kato, Masahiko and Suzuki, Hiroshi and Shimizu, Nobuyuki and Shimizu, Hayato and Keida, Takehiko and Fujita, Takashi and Fujita, Masaki and Nakamura, Keita and Nakamura, Makiko and Nakamura, Kentaro and Chinen, Toshiya and Meguro, Kentaro and Kikuchi, Tatsuro and Nishikido, Toshiyuki and Nakata, Masaya and Nakata, Marohito and Yamashita, Shizuya and Yamashita, Eiji and Yamashita, Tatsuya and Hirono, Akitoshi and Mitsudo, Kazuaki and Kadota, Kazushige and Makita, Noriko and Watanabe, Nagisa and Kawabata, Masaaki and Fujii, Kenichi and Fujii, Shinya and Okuda, Shinichi and Kobayashi, Hiroshi and Kobayashi, Shigeki and Moriuchi, Ikuo and Osato, Kazuo and Murakami, Tatsuaki and Shimada, Yoshifumi and Shimada, Katsunori and Misawa, Katsushi and Kokado, Hiromasa and Fukuoka, Yoshitomo and Takabatake, Syu and Takata, Yoshifumi and Miyagi, Manabu and Tanaka, Nobuhiro and Yamashina, Akira and Sudo, Shinji and Shimamura, Koichi and Nagashima, Michitaka and Kaneda, Tomoya and Ueda, Yasunori and Ueda, Kosei and Higashikata, Toshinori and Fujimori, Kanichi and Yagi, Masahiro and Takaki, Jyunko and Toyama, Takuji and Hirata, Tetsuo and Kamisihima, Kazuho and ... and Acute Decompensated Heart Failure and investigators of the Acute Decompensated Heart Failure Syndromes (ATTEND) registry
The American Journal of Cardiology, ISSN 0002-9149, 09/2017, Volume 120, Issue 5, pp. 809 - 816
The aim of this study was to evaluate the association of functional mitral regurgitation (FMR), preserved or reduced ejection fraction (EF), and ischemic or... 
VENTRICULAR SYSTOLIC DYSFUNCTION | PROGNOSTIC IMPLICATIONS | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | DETERMINANTS | DISEASE | RISK | DILATED CARDIOMYOPATHY | ECHOCARDIOGRAPHY | QUANTITATIVE DOPPLER ASSESSMENT | SEVERITY | Japan - epidemiology | Prospective Studies | Humans | Heart Failure - physiopathology | Male | Mitral Valve Insufficiency - epidemiology | Heart Ventricles - diagnostic imaging | Incidence | Echocardiography, Doppler | Myocardial Ischemia - physiopathology | Female | Registries | Ventricular Function, Left - physiology | Myocardial Ischemia - diagnosis | Heart Failure - mortality | Severity of Illness Index | Heart Failure - complications | Acute Disease | Survival Rate - trends | Stroke Volume - physiology | Mitral Valve Insufficiency - diagnosis | Heart Ventricles - physiopathology | Myocardial Ischemia - complications | Cause of Death - trends | Mitral Valve Insufficiency - etiology | Heart failure | Care and treatment | Mitral valve insufficiency | Patient outcomes | Analysis | Cardiac patients | Hypertension | Heart attacks | Cardiomyopathy | Mortality | Color | Disorders | Cardiovascular disease | Hospitalization | Patients | Discharge | Confidence intervals | Ultrasonic imaging | Ischemia | Regurgitation | Acute coronary syndromes | Health risk assessment | Heart diseases | Ejection
Journal Article
Journal Article
American Journal of Physiology, ISSN 1040-0605, 03/2011, Volume 300, Issue 3, p. L391
Reepithelialization of remodeled air spaces with bronchial epithelial cells is a prominent pathological finding in idiopathic pulmonary fibrosis (IPF) and is... 
Proteins | Cell growth | Pathogenesis | Respiratory diseases | Cystic fibrosis | Physiology | Gene expression
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2011, Volume 187, Issue 1, pp. 510 - 519
TLR3, one of the TLRs involved in the recognition of infectious pathogens for innate and adaptive immunity, primarily recognizes viral-associated dsRNA.... 
Journal Article
The American Journal of Physiology, ISSN 0002-9513, 03/2011, Volume 300, Issue 3, p. L391
Reepithelialization of remodeled air spaces with bronchial epithelial cells is a prominent pathological finding in idiopathic pulmonary fibrosis (IPF) and is... 
Physiological aspects | Genetic aspects | Pulmonary fibrosis | Transforming growth factors | Properties | Epithelial cells
Journal Article
Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society, ISSN 1343-3490, 2009, Volume 47, Issue 2, pp. 104 - 109
Journal Article
Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, ISSN 1343-3490, 02/2009, Volume 47, Issue 2, p. 104
A 63-year-old man was admitted to Jikei University Hospital, with anasarca, and dyspnea in May, 2004. Echocardiograms and CT scans showed massive pericardial... 
Heart Neoplasms - pathology | Adenocarcinoma - pathology | Mesothelioma - pathology | Humans | Middle Aged | Lung Neoplasms - pathology | Male | Neoplasms, Multiple Primary - pathology | Asbestosis - pathology | Pericardium
Journal Article
Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society, ISSN 1343-3490, 2008, Volume 46, Issue 12, pp. 1059 - 1064
Journal Article
International Journal of Clinical Practice, ISSN 1368-5031, 08/2015, Volume 69, Issue 8, pp. 820 - 828
Journal Article