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1. Full Text A photoelectrochemical aptasensor constructed with core-shell CuS-TiO2 heterostructure for detection of microcystin-LR
by Tang, Yunfei and Chai, Yun and Liu, Xiaoqiang and Liu, Peipei and Li, Lele and Yang, Liwei and Zhou, Yanmei and Ju, Huangxian and Cheng, Yunzhi
Biosensors and Bioelectronics, ISSN 0956-5663, 10/2018, Volume 117, pp. 224 - 231
In this work, a CuS-TiO heterojunction composite was prepared by dispersedly depositing CuS nanoparticles on TiO nanospheres surface with a hydrothermal... 
CuS-TiO2 heterojunction | CuS nanoparticles | TiO2 nanospheres | Photoelectrochemical aptasensor | Microcystin-LR | CuS-TiO | nanospheres | heterojunction | TiO | ASSISTED SYNTHESIS | ELECTROCHEMISTRY | CHEMISTRY, ANALYTICAL | ONE-POT | NANOSCIENCE & NANOTECHNOLOGY | NANOSTRUCTURES | MASS-SPECTROMETRY | QUANTUM DOTS | AMPLIFICATION | BIOPHYSICS | PHOTOCATALYTIC ACTIVITY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | HYDROGEN-PRODUCTION | IMMUNOSENSOR | NANOCOMPOSITE
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2. Full Text Surface-enhanced fluorescence immunosensor using Au nano-crosses for the detection of microcystin-LR
by Li, Yun and Sun, Jiadi and Sun, Xiulan and Wu, Longyun and Ji, Jian and Qian, Yongzhong
Biosensors and Bioelectronics, ISSN 0956-5663, 12/2014, Volume 62, pp. 255 - 260
A surface-enhanced fluorescence (SEF) immunosensor for the detection of microcystin-LR was developed using Au nano-crosses as fluorescence enhancement... 
Surface enhanced fluorescence immunosensor | Au nano-crosses | Microcystin-LR | ELECTROCHEMISTRY | CHEMISTRY, ANALYTICAL | Surface enhanced fluorescence | GOLD NANORODS | SENSOR | NANOSCIENCE & NANOTECHNOLOGY | NANOSTRUCTURES | SILVER NANOPARTICLES | DEPENDENCE | EXTRACTION | BIOPHYSICS | LIQUID-CHROMATOGRAPHY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | immunosensor | EMISSION | Nanotubes - ultrastructure | Gold | Microscopy, Electron, Transmission | Immunoassay - instrumentation | Microcystins - immunology | Humans | Microcystins - toxicity | Food Microbiology | Microcystins - analysis | Carbocyanines | Animals | Seafood - microbiology | Immunoassay - methods | Biosensing Techniques - instrumentation | Biosensing Techniques - methods | Seafood - toxicity | Fluorescent Dyes | Metal Nanoparticles - ultrastructure | Fluorescence | Safety and security measures | Adsorption | Food contamination | Food | Nanoparticles | Seafood | Immunosensors | Nanostructure | Biosensors | Nanorods
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3. Full Text Development of waste biomass based sorbent for removal of cyanotoxin microcystin-LR from aqueous phases
by Kim, Sok and Yun, Yeoung-Sang and Choi, Yoon-E
Bioresource Technology, ISSN 0960-8524, 01/2018, Volume 247, pp. 690 - 696
The purpose of this study was to establish the strategy to remove the cyanotoxin microcystin-LR (MC-LR) from aqueous solution with the use of biosorption... 
Polyethylenimine (PEI) | Biosorption | Biomass | Adsorbent | Microcystin-LR | CARBON | ESCHERICHIA-COLI BIOMASS | ENERGY & FUELS | GRAPHENE | REACTIVE DYE | AGRICULTURAL ENGINEERING | BACILLUS-SUBTILIS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | EQUILIBRIUM | BINDING | DERIVATIVES | Adsorption | Marine toxins | Escherichia coli
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4. Full Text Microcystin-LR promotes necroptosis in primary mouse hepatocytes by overproducing reactive oxygen species
by Wu, Yun-Li and He, Yun and Shi, Jia-Jian and Zheng, Tian-Xiu and Lin, Xu and Lin, Xin-Jian
Toxicology and Applied Pharmacology, ISSN 0041-008X, 08/2019, Volume 377, p. 114626
Microcystin-LR (MC-LR) is a type of cyclic heptapeptide toxin produced by cyanobacteria during bloom events. MC-LR-induced cell death is critically involved in... 
Cyanbacteria | Necroptosis | Microcystins | Eutrophication | Apoptosis | Liver injury | OXIDATIVE STRESS | INDUCED APOPTOSIS | MIXED LINEAGE KINASE | DEPENDENT APOPTOSIS | MECHANISMS | CELL-DEATH | NECROSIS | PHARMACOLOGY & PHARMACY | TOXICOLOGY | RIP3 | UP-REGULATION | EXPRESSION
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5. Full Text A novel visible-light driven photoelectrochemical immunosensor based on multi-amplification strategy for ultrasensitive detection of microcystin-LR
by Wei, Jie and Qileng, Aori and Yan, Yun and Lei, Hongtao and Zhang, Shengsen and Liu, Weipeng and Liu, Yingju
Analytica Chimica Acta, ISSN 0003-2670, 11/2017, Volume 994, pp. 82 - 91
An ultrasensitive photoelectrochemical (PEC) immunoassay based on multiple signal amplification strategy was fabricated for the detection of microcystin-LR... 
CdS/TiO2 nanorod arrays | Photoelectrochemical immunosensor | Fe3O4@polydopamine | Microcystin-LR | nanorod arrays | @polydopamine | CdS/TiO | CHEMISTRY, ANALYTICAL | CDS QUANTUM DOTS | ELECTROCHEMICAL IMMUNOSENSOR | NANOPARTICLES | NONENZYMATIC IMMUNOSENSOR | NANOROD | ELECTRODE | INDUCED BIOCATALYTIC PRECIPITATION | IMMUNOASSAY | BIOSENSOR | SAMPLES | Immunoassay | Limit of Detection | Reproducibility of Results | Electrochemical Techniques | Hydrogen Peroxide | Titanium | Cadmium Compounds | Microcystins - analysis | Precipitation (Meteorology)
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6. Full Text A photoelectrochemical aptasensor constructed with core-shell CuS-TiO.sub.2 heterostructure for detection of microcystin-LR
by Tang, Yunfei and Chai, Yun and Liu, Xiaoqiang and Li, Lele and Yang, Liwei and Liu, Peipei and Zhou, Yanmei and Ju, Huangxian and Cheng, Yunzhi
Biosensors and Bioelectronics, ISSN 0956-5663, 10/2018, Volume 117, p. 224
Analysis | Environmental monitoring
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7. Full Text Biodegradation mechanism of microcystin-LR by a novel isolate of Rhizobium sp. TH and the evolutionary origin of the mlrA gene
by Zhu, Xiaoyun and Shen, Yitian and Chen, Xiaoguo and Hu, Yue O.O and Xiang, Huiyi and Tao, Jia and Ling, Yun and Science for Life Laboratory, SciLifeLab and Centra and Skolan för bioteknologi (BIO) and KTH and Genteknologi
International Biodeterioration & Biodegradation, ISSN 0964-8305, 11/2016, Volume 115, pp. 17 - 25
The frequent presence of microcystin (MC) in eutrophic water bodies worldwide poses a serious threat to ecosystems. Biodegradation has been extensively... 
Degradation | Microcystin | mlrA gene | Evolutionary origin | Rhizobium | Mechanism | DEGRADING BACTERIUM | CYANOBACTERIAL HEPATOTOXIN MICROCYSTIN | IDENTIFICATION | ENVIRONMENTAL SCIENCES | REMOVAL | LAKE TAIHU | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ENZYMATIC PATHWAY | SP-NOV | WATER | Biodegradation | Analysis | Genes | Escherichia coli | Green technology | Genetic research | Bacteria | Evolution | Phylogeny | Proteobacteria | Rate constants | eutrophic environment | Toxic materials | Sphingomonadales | Phylogenetic analysis | evolutionary biology | toxin | Rhizobium sp | phylogenetics | Natural Sciences | Horizontal gene transfer | Microcystins | Alphaproteobacteria | Biological Sciences | Mechanisms | Gene transfer | gene | Environmental sample | rhizobacterium | Gene expression | Strain | Naturvetenskap | reaction kinetics | Biologiska vetenskaper | Bacteria (microorganisms) | Gammaproteobacteria | First-order rate constants | Heterologous expression
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8. Full Text Role of nitric oxide in the genotoxic response to chronic microcystin-LR exposure in human–hamster hybrid cells
by Wang, Xiaofei and Wang, Xinan and Wang, Yichen and Wang, Meimei and Huang, Pei and Liu, Yun and Du, Hua and Hei, Tom K and Wu, Lijun and Xu, An
Journal of Environmental Sciences, ISSN 1001-0742, 03/2015, Volume 29, pp. 210 - 218
Microcystin-LR (MC-LR) is the most abundant and toxic microcystin congener and has been classified as a potential human carcinogen (Group 2B) by the... 
Nitric oxide | Genotoxicity | Microcystin-LR (MC-LR) | Chronic exposure | INDUCED DNA-DAMAGE | OXIDATIVE STRESS | RAT HEPATOCYTES | MAMMALIAN-CELLS | ENVIRONMENTAL SCIENCES | IN-VITRO | REPAIR | MUTATION | LIVER | DRINKING-WATER | EXPRESSION | DNA Damage - drug effects | Hybridomas - drug effects | Cricetinae | Animals | Humans | Mitochondria - metabolism | Mitochondria - drug effects | Mutation | Microcystins - toxicity | Nitric Oxide - metabolism | Carcinogens | Inhibitors | Congeners | Exposure | Mammals | Survival
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9. Full Text Microcystin-LR bioconcentration induces antioxidant responses in the digestive gland of two marine bivalves Crassostrea gigas and Mytilus edulis
by Kim, Young Dae and Kim, Youn-Jung and Kim, Won Jin and Kim, Jang Kyun and Shin, Yun Kyung and Lee, Do-Hee and Rhee, Jae-Sung
Aquatic Toxicology, ISSN 0166-445X, 07/2017, Volume 188, pp. 119 - 129
Microcystins (MCs) are a major group of potent cyanobacterial toxins found in freshwater and even brackish waterbodies. To understand the putative correlation... 
Microcystin | Oxidative stress | Mytilus edulis | Bivalve | Bioconcentration | Crassostrea gigas | LIPID-PEROXIDATION | AQUATIC ANIMALS | CYANOBACTERIAL TOXINS | BIOACCUMULATION | BIOTRANSFORMATION | CRAYFISH PROCAMBARUS-CLARKII | GLUTATHIONE | MARINE & FRESHWATER BIOLOGY | TOXICOLOGY | ACCUMULATION | WATER | Crassostrea - drug effects | Malondialdehyde - metabolism | Glutathione Peroxidase - metabolism | Crassostrea - metabolism | Glutathione - metabolism | Glutathione Reductase - metabolism | Mytilus edulis - metabolism | Glutathione Transferase - metabolism | Water Pollutants, Chemical - pharmacokinetics | Gastrointestinal Tract - drug effects | Microcystins - toxicity | Gastrointestinal Tract - metabolism | Catalase - metabolism | Microcystins - pharmacokinetics | Mytilus edulis - drug effects | Animals | Water Pollutants, Chemical - toxicity | Superoxide Dismutase - metabolism | Antioxidants | Enzymes | Research institutes | Goods and services tax | Marine sciences | Superoxide | Oysters | Crassostrea | Glutathione transferase | Index Medicus
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10. A novel visible-light driven photoelectrochemical immunosensor based on multi-amplification strategy for ultrasensitive detection of microcystin-LR
by Jie Wei and Aori Qileng and Yun Yan and Hongtao Lei and Shengsen Zhang and Weipeng Liu and Yingju Liu
Analytica Chimica Acta, ISSN 0003-2670, 11/2017, Volume 994, p. 82
An ultrasensitive photoelectrochemical (PEC) immunoassay based on multiple signal amplification strategy was fabricated for the detection of microcystin-LR... 
Immunoassay | Antigens | Recombination | Hydrogen peroxide | Microcystin-LR | Horseradish peroxidase | Immunosensors | Steric hindrance | Catalytic activity | Nanoparticles | Electrodes | Amplification | Photoelectric effect | Absorption | Photocurrent | Reproducibility | Oxidation | Peroxidase | Naphthol | Catalysis | Environmental monitoring | Iron oxides | Titanium dioxide | Nanorods
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11. Full Text Predicting postoperative vomiting among orthopedic patients receiving patient-controlled epidural analgesia using SVM and LR
by Wu, Hsin-Yun and Gong, Cihun-Siyong Alex and Lin, Shih-Pin and Chang, Kuang-Yi and Tsou, Mei-Yung and Ting, Chien-Kun
Scientific Reports, ISSN 2045-2322, 06/2016, Volume 6, Issue 1, p. 27041
Patient-controlled epidural analgesia (PCEA) has been applied to reduce postoperative pain in orthopedic surgical patients. Unfortunately, PCEA is occasionally... 
RISK-FACTORS | PAIN | ORTHOGNATHIC SURGERY | MULTIDISCIPLINARY SCIENCES | NAUSEA | SUPPORT VECTOR MACHINE | CATHETER INSERTION | Prognosis | Analgesia, Patient-Controlled - methods | Area Under Curve | Humans | Middle Aged | Fentanyl | Logistic Models | Male | Analgesia, Epidural - methods | Support Vector Machine | Postoperative Nausea and Vomiting - diagnosis | Postoperative Nausea and Vomiting - prevention & control | Pain, Postoperative - prevention & control | Bupivacaine | Orthopedic Procedures | Aged, 80 and over | Female | ROC Curve | Aged | Retrospective Studies | Pain Measurement | Pain, Postoperative - physiopathology | Anesthetics, Local
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12. Full Text Essential Roles of p53 and MAPK Cascades in Microcystin-LR-Induced Germline Apoptosis in Caenorhabditis elegans
by Wang, Shun-Chang and Geng, Zhi-Zhong and Wang, Yun and Tong, Zhong-Hua and Yu, Han-Qing
Environmental Science & Technology, ISSN 0013-936X, 03/2012, Volume 46, Issue 6, pp. 3442 - 3448
Hepatotoxin microcystin-LR (MC-LR) can induce apoptosis in a variety of cells. However, the underlying pathways of MC-LR-induced apoptosis have not been well... 
PROGRAMMED CELL-DEATH | ENVIRONMENTAL SCIENCES | SIGNALING PATHWAYS | ENGINEERING, ENVIRONMENTAL | DNA-DAMAGE | IN-VIVO | LIVER | CYCLE ARREST | EXPRESSION | DAMAGE CHECKPOINT PROTEIN | EXPOSURE | ERK | Caenorhabditis elegans - metabolism | Marine Toxins - toxicity | Apoptosis - drug effects | Caenorhabditis elegans - genetics | Tumor Suppressor Protein p53 - metabolism | Bacterial Toxins - toxicity | Caenorhabditis elegans Proteins - metabolism | Microcystins - toxicity | Proto-Oncogene Proteins c-bcl-2 - metabolism | Animals | Caenorhabditis elegans - drug effects | RNA Interference | Signal Transduction - drug effects | Telomere-Binding Proteins - metabolism | Repressor Proteins - metabolism | Mitogen-Activated Protein Kinases - metabolism | Index Medicus
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13. Full Text Adsorption of Microcystin-LR from Water with Iron Oxide Nanoparticles
by Yu-qiong Gao and Nai-yun Gao and Yang Deng and Jin-shan Gu and Yi-chen Shen and Shao-xiang Wang
Water Environment Research, ISSN 1061-4303, 7/2012, Volume 84, Issue 7, pp. 562 - 568
Adsorption of microcystin-LR (MC-LR) from water using iron oxide (α-Feâ‚‚O₃) nanoparticles was investigated in this study. Adsorption of MC-LR adsorption was... 
Nanoparticles | Adsorption | Isotherms | Carboxyl compounds | Sorbents | Kinetics | Iron oxides | Electrostatics | Adsorbents | carboxyl group | adsorption | kinetics | inorganic cations | Inorganic cations | Carboxyl group | PARTICLES | MECHANISM | SORPTION | SIZE | IONS | WATER RESOURCES | ENVIRONMENTAL SCIENCES | REMOVAL | ENGINEERING, ENVIRONMENTAL | ACTIVATED CARBON | DISSOLVED ORGANIC-MATTER | LIMNOLOGY | CLAY | HUMIC-ACID | Time Factors | Microcystins - chemistry | Metal Nanoparticles - chemistry | Water Pollutants, Chemical - chemistry | Ferric Compounds - chemistry | Hydrogen-Ion Concentration
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14. Full Text The first report of RPSA polymorphisms, also called 37/67 kDa LRP/LR gene, in sporadic Creutzfeldt-Jakob disease (CJD)
by Yun, Jisuk and Jin, Hyoung-Tae and Lee, Yun-Jung and Choi, Eun-Kyoung and Carp, Richard I and Jeong, Byung-Hoon and Kim, Yong-Sun
BMC Medical Genetics, ISSN 1471-2350, 08/2011, Volume 12, Issue 1, pp. 108 - 108
Background: Although polymorphisms of PRNP, the gene encoding prion protein, are known as a determinant affecting prion disease susceptibility, other genes... 
PRION PROTEIN | PRPSC PROPAGATION | QUANTITATIVE TRAIT LOCI | PRNP | KOREAN POPULATION | GENETICS & HEREDITY | LAMININ RECEPTOR PRECURSOR | MICE | IDENTIFICATION | VECTORS | INCUBATION PERIOD | Genetic Predisposition to Disease | Exons | Introns | Ribosomal Proteins - genetics | Gene Frequency | Humans | Middle Aged | Genotype | Male | DNA Primers - chemistry | Receptors, Laminin - genetics | Sequence Analysis, DNA | Case-Control Studies | Alleles | Polymerase Chain Reaction | Aged, 80 and over | DNA Primers - metabolism | Female | Aged | Polymorphism, Single Nucleotide | Creutzfeldt-Jakob Syndrome - genetics | Care and treatment | Ribosomal proteins | Creutzfeldt-Jakob disease | Genetic aspects | Research | Single nucleotide polymorphisms | Health aspects | Risk factors
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15. Full Text Combined Effects of Temperature and the Microcystin MC-LR on the Feeding Behavior of the Rotifer Brachionus calyciflorus
by Xiang, Xian-Ling and Chen, Ying-Ying and Xu, Qiu-Lei and Zhu, Ling-Yun and Wen, Xin-Li and Xi, Yi-Long
Bulletin of Environmental Contamination and Toxicology, ISSN 0007-4861, 10/2017, Volume 99, Issue 4, pp. 493 - 499
The aim of this study was to investigate the responses in filtration and grazing rates of five rotifer strains of the species Brachionus calyciflorus under... 
Pollution, general | Temperature | Environmental Health | Feeding behavior | Ecotoxicology | Microcystin | Environment | Waste Water Technology / Water Pollution Control / Water Management / Aquatic Pollution | Brachionus calyciflorus | Rotifer | Environmental Chemistry | Soil Science & Conservation | AERUGINOSA | POPULATION-GROWTH | DAPHNIA | TOXICITY | ZOOPLANKTON | DEMOGRAPHY | LIFE-HISTORY CHARACTERISTICS | ENVIRONMENTAL SCIENCES | CYANOBACTERIA | TOXICOLOGY | PLICATILIS | EXPOSURE | Animals | Water Pollutants, Chemical - toxicity | Rotifera - physiology | Tropical Climate | Rotifera - drug effects | China | Environmental Monitoring - methods | Microcystins - toxicity | Water Pollutants, Chemical - analysis | Feeding Behavior - drug effects | Microcystins - analysis | Filtration | Plankton | Temperature effects | Toxins | Aquatic organisms | Grazing
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