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Science, ISSN 0036-8075, 02/2015, Volume 347, Issue 6225, pp. 1002 - 1006
  When stem cells progress from an embryonic pluripotent state toward a particular lineage, molecular switches dismantle the transcription factor network that... 
Studies | Modifications | MicroRNAs | Government regulations | Depletion | Ribonucleic acids | Stem cells | Decay | In vivo methods and tests | Mammals | Methylation
Journal Article
Nature Methods, ISSN 1548-7091, 08/2010, Volume 7, Issue 8, pp. 631 - 633
We generated a system for in vivo visualization and analysis of mammalian mRNA transcriptional kinetics of single alleles in real time, using single-gene... 
ORIGIN | REPLICATION | GENE | PARTICLES | RESOLUTION | BIOCHEMICAL RESEARCH METHODS | DYNAMICS | IN-SITU | REAL-TIME | DNA Replication | Transcription, Genetic | Kinetics | Cyclin D1 - genetics | Humans | Alleles | Allelomorphism | Physiological aspects | Genetic aspects | Research | Genetic transcription | Cell cycle | Cellular biology | Ribonucleic acid--RNA | Mammals | Research methodology | Index Medicus
Journal Article
eLife, ISSN 2050-084X, 11/2016, Volume 5, Issue 2016
Signal propagation from the cell membrane to a promoter can induce gene expression. To examine signal transmission through sub-cellular compartments and its... 
MOLECULAR-MECHANISM | CANCER-CELLS | LOCALIZATION | CENTROSOME | IN-VIVO | BIOLOGY | GENE-EXPRESSION | ADHERENS JUNCTIONS | GROWTH-FACTOR | MAMMALIAN-CELLS | FEEDBACK LOOP | Wnt3A Protein - metabolism | Cell Cycle - genetics | Cyclin D1 - metabolism | Humans | Cytosol - drug effects | RNA, Messenger - metabolism | Adherens Junctions - metabolism | Wnt3A Protein - pharmacology | Cell Nucleus - metabolism | Lithium Chloride - pharmacology | HEK293 Cells | Transcription, Genetic | Cell Membrane - metabolism | Membrane Proteins - metabolism | Single-Cell Analysis | Cell Membrane - drug effects | Wnt Signaling Pathway | Wnt3A Protein - genetics | Membrane Proteins - genetics | RNA, Messenger - genetics | Cytosol - ultrastructure | Gene Expression Regulation | Cell Membrane - ultrastructure | Cell Nucleus - ultrastructure | beta Catenin - metabolism | beta Catenin - genetics | ADAM Proteins - metabolism | Cyclin D1 - genetics | Adherens Junctions - drug effects | Adherens Junctions - ultrastructure | Cytosol - metabolism | ADAM Proteins - genetics | Cell Cycle - drug effects | Cell Nucleus - drug effects | Transcription factors | Wnt protein | Lithium chloride | Adherens junctions | Gene expression | Cyclin D1 | Experiments | Proteins | β-catenin | Signal transduction | Transcription activation | Cell cycle | Cytoplasm | Index Medicus
Journal Article
Methods in molecular biology (Clifton, N.J.), 2011, Volume 714, pp. 249 - 263
The gene expression pathway begins in the nucleus as a gene receives a cue to transcribe, and typically ends in the cytoplasm with the production of the... 
Capsid Proteins - metabolism | Cell Survival | Humans | RNA, Messenger - genetics | RNA, Messenger - analysis | Repetitive Sequences, Nucleic Acid | In Situ Hybridization, Fluorescence | Molecular Imaging - methods | HeLa Cells | RNA, Messenger - metabolism | Capsid Proteins - genetics | Index Medicus
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 10/2017, Volume 8, pp. 1211 - 1211
Adoptive cell therapy (ACT) of autologous tumor infiltrating lymphocytes (TIL) is an effective immunotherapy for patients with solid tumors, yielding objective... 
CD137 | Adoptive cell therapy | Tumor infiltrating lymphocytes (TIL) | Tumor antigen | Neoantigen | Melanoma | neoantigen | REGRESSION | METASTATIC MELANOMA PATIENTS | melanoma | ANTIGENS | CANCER-IMMUNOTHERAPY | IMMUNOLOGY | adoptive cell therapy | SOMATIC MUTATIONS | TUMOR-INFILTRATING LYMPHOCYTES | tumor antigen | RESPONSES | tumor infiltrating lymphocytes (TIL) | PATIENT
Journal Article
JOURNAL FOR IMMUNOTHERAPY OF CANCER, ISSN 2051-1426, 05/2019, Volume 7, Issue 1, pp. 135 - 135
Background: Targeting epitopes derived from neo-antigens (or "neo-epitopes") represents a promising immunotherapy approach with limited off-target effects.... 
T cell activation | TUMOR | IMMUNOLOGY | Machine Learning | CANCER | PREDICTION | NEED | ONCOLOGY | IMMUNOTHERAPY | CLASS-I | MHC-binding peptides | Neoantigen | TOOLS | Algorithms | Research | T cells | Antigenic determinants | Proteins | Antigens | Peptides | Lymphocytes | Melanoma | T cell receptors | Internet | Mutation | Bioinformatics | Cancer
Journal Article
eLife, ISSN 2050-084X, 11/2016, Volume 5
Signal propagation from the cell membrane to a promoter can induce gene expression. To examine signal transmission through sub-cellular compartments and its... 
RNA | Genetic research | Cadherins | Genetic aspects | Genetic transcription | Research | Wnt proteins
Journal Article
Science, ISSN 0036-8075, 02/2015, Volume 347, Issue 6225
Naive and primed pluripotent states retain distinct molecular properties, yet limited knowledge exists on how their state transitions are regulated. Here, we... 
Methylation | Messenger RNA | Cell research | Physiological aspects | Genetic research | Research | Cell differentiation
Journal Article
Journal Article
Life Science Alliance, ISSN 2575-1077, 2018, Volume 1, Issue 5, pp. e201800086 - e201800086
Imaging of transcription by quantitative fluorescence-based techniques allows the examination of gene expression kinetics in single cells. Using a cell system... 
Journal Article
Histochemistry and Cell Biology, ISSN 0948-6143, 7/2013, Volume 140, Issue 1, pp. 71 - 79
Journal Article
Journal Article
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