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Nature Medicine, ISSN 1078-8956, 01/2007, Volume 13, Issue 1, pp. 100 - 106
Journal Article
Scientific Reports, ISSN 2045-2322, 10/2016, Volume 6, Issue 1, p. 33987
Epigraph is an efficient graph-based algorithm for designing vaccine antigens to optimize potential T-cell epitope (PTE) coverage. Epigraph vaccine antigens... 
STRAINS | MOSAIC VACCINES | VIRUS | PROTECTION | IMMUNE-RESPONSES | COVERAGE | MULTIDISCIPLINARY SCIENCES | CONSENSUS | FOUNDER | T-LYMPHOCYTE RESPONSES | BREADTH | Chronic infection | Antigens | T cell receptors | Lymphocytes T | Vaccines | Epitopes | MATHEMATICS AND COMPUTING | software | vaccines | 60 APPLIED LIFE SCIENCES
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 1/2008, Volume 36, Issue suppl_1, pp. D512 - D516
The hepatitis C virus (HCV) is a significant public health threat worldwide. The virus is highly variable and evolves rapidly, making it an elusive target for... 
SYSTEM | VIRUS GENOTYPES | BIOCHEMISTRY & MOLECULAR BIOLOGY | Sequence Analysis, Protein | Sequence Analysis, RNA | Viral Proteins - chemistry | Humans | Genes, Viral | Hepatitis C - virology | Databases, Genetic | Hepacivirus - genetics | Viral Proteins - genetics | Genotype | Software | Internet
Journal Article
Journal Article
Hepatology, ISSN 0270-9139, 12/2007, Volume 46, Issue 6, pp. 1713 - 1721
Outcomes of infection with hepatitis C virus (HCV) vary widely, from asymptomatic clearance to chronic infection, leading to complications that include... 
HIV-1 | ALLELES | HLA CLASS-I | LIVER-TRANSPLANTATION | IMMUNE-SYSTEM | DATABASE | DOMINANT INFLUENCE | POLYMORPHISM | NATURAL-HISTORY | GASTROENTEROLOGY & HEPATOLOGY | VIRAL CLEARANCE | Haplotypes | Hepatitis C - immunology | Humans | Alleles | Hepatitis C - genetics | Heterozygote | HLA Antigens - genetics
Journal Article
Journal Article
PLoS Pathogens, ISSN 1553-7366, 04/2018, Volume 14, Issue 4, p. e1006944
Despite extensive genetic diversity of HIV-1 in chronic infection, a single or few maternal virus variants become the founders of an infant's infection. These... 
ESCAPE VARIANTS | SUBTYPE | ENV GENES | PERINATAL TRANSMISSION | RISK-FACTORS | MICROBIOLOGY | ANTIRETROVIRAL THERAPY | ANTIBODY VRC01 | VIROLOGY | TYPE-1 VARIANTS | INFECTION | TO-CHILD TRANSMISSION | PARASITOLOGY | env Gene Products, Human Immunodeficiency Virus - immunology | HIV Infections - virology | Humans | Infant | Neutralization Tests | Infectious Disease Transmission, Vertical | HIV-1 - genetics | Peripartum Period | Genetic Variation | Pregnancy | Pregnancy Complications, Infectious - etiology | Pregnancy Complications, Infectious - metabolism | HIV Infections - immunology | Antibodies, Neutralizing - immunology | Plasma - metabolism | env Gene Products, Human Immunodeficiency Virus - genetics | HIV Antibodies - immunology | Female | HIV Infections - transmission | Viral antibodies | AIDS vaccines | Analysis | Antibodies | Infants | Research | Health aspects | HIV infection | Risk factors | Plasma | Immunoglobulins | Sensitivity analysis | Breastfeeding & lactation | Laboratories | Immunoglobulin G | Health risks | Chronic infection | Viruses | Infections | Glycoproteins | Genomes | Genetic diversity | Amplification | Babies | Disease transmission | Acquired immune deficiency syndrome--AIDS | Antiretroviral agents | Human immunodeficiency virus--HIV | Neutralizing | Neutralization | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
Journal Article
Nucleic acids research, ISSN 0305-1048, 2015, Volume 43, Issue 1, pp. W213 - W219
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e44769
We report the rational design and in vivo testing of mosaic proteins for a polyvalent pan-filoviral vaccine using a computational strategy designed for the... 
RESPONSES | IMMUNITY | HEMORRHAGIC-FEVER | MULTIDISCIPLINARY SCIENCES | INFECTION | HUMAN-IMMUNODEFICIENCY-VIRUS | EBOLA | BREADTH | Hepacivirus - immunology | Humans | AIDS Vaccines - immunology | Viral Proteins - immunology | Drug Design | Ebola Vaccines - immunology | Female | Epitopes, T-Lymphocyte - immunology | Filoviridae Infections - immunology | T-Lymphocytes, Cytotoxic - immunology | Computational Biology - methods | Enzyme-Linked Immunosorbent Assay | Mice, Inbred C57BL | Filoviridae - metabolism | Ebola Vaccines - administration & dosage | Cross Reactions - immunology | Viral Vaccines - administration & dosage | Viral Hepatitis Vaccines - immunology | Filoviridae - immunology | Animals | Filoviridae Infections - prevention & control | Filoviridae Infections - virology | Survival Analysis | Antibodies, Viral - immunology | Mice | Viral Vaccines - immunology | AIDS vaccines | Analysis | Ebola virus infections | T cells | Hepatitis C virus | HIV (Viruses) | Recombinant proteins | Antigenic determinants | Epidemics | Viral diseases | Cytotoxicity | Outbreaks | Viruses | Lymphocytes T | Biology | Infections | Vaccines | Regulatory approval | Genetic algorithms | Design | Proteins | Ebola virus | Hepatitis | Taxa | Biomedical materials | Human immunodeficiency virus--HIV | Phylogenetics | Biocompatibility | Strains (organisms) | Species | Recombinant | Medical research | Encephalitis | Mosaics | Cross-reactivity | Genetic diversity | Epitopes | Biophysics | Fever | Virology | Infectious diseases | Immunogenicity | Computation | Computer applications | Fatalities | In vivo methods and tests | Recombinants | Hepatitis C | Laboratory animals | HIV | Human immunodeficiency virus
Journal Article