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Journal Article
Journal Article
Journal Article
Journal Article
Science, ISSN 0036-8075, 6/2003, Volume 300, Issue 5625, pp. 1584 - 1587
Although the role of Toll-like receptors in extracellular bacterial sensing has been investigated intensively, intracellular detection of bacteria through Nod... 
Molecules | Pathogens | Epithelial cells | Cell nucleus | Cell lines | HeLa cells | Bacteria | Mass spectroscopy | Reports | Pattern recognition | Gram negative bacteria | ACTIVATION | CROHNS-DISEASE | IMMUNE-RESPONSES | FAMILY MEMBER | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | INNATE | RECOGNITION PROTEIN | TOLL | NF-KAPPA-B | DROSOPHILA | Oligopeptides - analysis | Epithelial Cells - metabolism | Gram-Positive Bacteria - chemistry | Humans | Peptidoglycan - chemistry | NF-kappa B - metabolism | NF-kappa B - chemistry | Gram-Negative Bacteria - immunology | Trisaccharides - chemistry | Antigens, Differentiation - metabolism | Carrier Proteins - chemistry | Interleukin-8 - metabolism | Gram-Positive Bacteria - immunology | Oligopeptides - chemistry | Cytoplasm - microbiology | Carrier Proteins - physiology | Protein Structure, Tertiary | Cell Line | Signal Transduction | Intracellular Signaling Peptides and Proteins | Nod2 Signaling Adaptor Protein | Myeloid Differentiation Factor 88 | Immunity, Innate | Amino Acid Motifs | Trisaccharides - analysis | Adaptor Proteins, Signal Transducing | Animals | Carrier Proteins - metabolism | Gram-Negative Bacteria - chemistry | Epithelial Cells - microbiology | Lipopolysaccharides - pharmacology | Mice | Nod1 Signaling Adaptor Protein | Peptidoglycan - pharmacology | Receptors, Immunologic - metabolism | Cytoplasm | Immune response | Research | Molecular biology | Immunology
Journal Article
Journal Article
Nature, ISSN 0028-0836, 02/2005, Volume 433, Issue 7025, pp. 523 - 527
Toll-like receptor 2 (TLR2) is required for the recognition of numerous molecular components of bacteria, fungi and protozoa. The breadth of the ligand... 
TOLL-LIKE RECEPTOR-2 | IMMUNE-RESPONSE | PATTERN-RECOGNITION | LIPOTEICHOIC ACID | GENE | METABOLISM | MULTIDISCIPLINARY SCIENCES | FATTY-ACID | LIPOPOLYSACCHARIDE | IDENTIFICATION | LIPOPROTEINS | Peptidoglycan - metabolism | Toll-Like Receptor 2 | CD36 Antigens - genetics | Membrane Glycoproteins - metabolism | Staphylococcus aureus - physiology | Humans | Membrane Glycoproteins - chemistry | Peptidoglycan - chemistry | Zymosan - pharmacology | Mutagenesis - drug effects | Toll-Like Receptors | CD36 Antigens - metabolism | Gene Deletion | Receptors, Cell Surface - chemistry | Staphylococcal Infections - microbiology | Dimerization | Oligopeptides - chemistry | Staphylococcal Infections - metabolism | Cell Line | Oligopeptides - chemical synthesis | Glycerides - chemistry | Staphylococcal Infections - genetics | Signal Transduction | Staphylococcal Infections - immunology | Mice, Inbred C57BL | Membrane Glycoproteins - agonists | Receptors, Cell Surface - agonists | Receptors, Cell Surface - metabolism | Glycerides - metabolism | Mutation - genetics | Immunologic Deficiency Syndromes - chemically induced | Ethylnitrosourea - pharmacology | Mice, Knockout | Staphylococcus aureus - chemistry | Homozygote | Glycerides - pharmacology | Phenotype | Animals | Aging - physiology | Receptors, Cell Surface - deficiency | Mice | Oligopeptides - pharmacology | Peptidoglycan - pharmacology | Lipopeptides | Tumor Necrosis Factor-alpha - biosynthesis | Membrane Glycoproteins - deficiency | Rodents | Immunology | Sensors
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2013, Volume 288, Issue 22, pp. 15654 - 15667
Streptococcus pneumoniae is a Gram-positive human pathogen with a complex lipoteichoic acid (pnLTA) structure. Because the current structural model for pnLTA... 
TEICHOIC-ACIDS | PRELIPOPROTEINS | GLYCOSPHINGOLIPIDS | RECOGNITION | FORSSMAN | BIOSYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GANGLIOSIDES | RECEPTOR | STAPHYLOCOCCUS-AUREUS | GROUP-B | Leukocytes, Mononuclear - metabolism | Adjuvants, Immunologic - pharmacology | Species Specificity | Humans | Lipopolysaccharides - metabolism | Male | Teichoic Acids - chemistry | Lipopolysaccharides - immunology | Lipopolysaccharides - genetics | Streptococcus pneumoniae - immunology | Streptococcus pneumoniae - chemistry | Adjuvants, Immunologic - chemistry | Streptococcus pneumoniae - metabolism | Teichoic Acids - pharmacology | Leukocytes, Mononuclear - immunology | Adjuvants, Immunologic - metabolism | Streptococcus pneumoniae - genetics | Teichoic Acids - metabolism | Adjuvants, Immunologic - genetics | Staphylococcus aureus - metabolism | Staphylococcus aureus - genetics | Teichoic Acids - genetics | Models, Molecular | Antibodies, Heterophile - immunology | Teichoic Acids - immunology | Toll-Like Receptor 2 - metabolism | Interleukin-6 - secretion | Staphylococcus aureus - chemistry | Interleukin-6 - immunology | Lipopolysaccharides - pharmacology | Toll-Like Receptor 2 - immunology | Antibodies, Bacterial - immunology | Leukocytes, Mononuclear - cytology | Staphylococcus aureus - immunology | Lipopolysaccharides - chemistry | Mutation | Analytical Chemistry | NMR | Structural Biology | Lipoteichoic Acid | Innate Immunity | Mass Spectrometry (MS) | Glycobiology and Extracellular Matrices | Immunostimulatory Potency | Forssman Antigen | Streptococcus pneumoniae
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2006, Volume 103, Issue 16, pp. 6392 - 6397
Journal Article
PLoS Pathogens, ISSN 1553-7366, 05/2012, Volume 8, Issue 5, p. e1002667
Journal Article