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1. Emerging role of G-Quadruplex DNA as target in anticancer therapy
by Cimino-Reale, Graziella and Zaffaroni, Nadia and Folini, Marco
Current pharmaceutical design, ISSN 1381-6128, 2016, Volume 22, Issue 44, pp. 6612 - 6624
Telomeres | Mitochondrial DNA | Gene promoter | Non-B DNA | G-quadruplex | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology
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2. Targeting heparan sulfate proteoglycans and their modifying enzymes to enhance anticancer chemotherapy efficacy and overcome drug resistance
by Lanzi, Cinzia and Zaffaroni, Nadia and Cassinelli, Giuliana
Current medicinal chemistry, ISSN 0929-8673, 08/2017, Volume 24, Issue 26, pp. 2860 - 2886
Sulfatase inhibitor | Heparanase inhibitor | Heparanase | Anticancer chemotherapy | Anticancer drug resistance | Heparan sulfate mimic | Heparan sulfate proteoglycan | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Neoplasms - metabolism | Animals | Heparan Sulfate Proteoglycans - metabolism | Enzyme Inhibitors - chemistry | Humans | Enzyme Inhibitors - pharmacology | Antineoplastic Agents - pharmacology | Heparan Sulfate Proteoglycans - antagonists & inhibitors | Antineoplastic Agents - chemistry | Drug Resistance, Neoplasm - drug effects | Neoplasms - drug therapy | Heparan sulfate | Enzymes | Proteoglycans | Effectiveness | Drug resistance | Sulfates | Mimicry | Sulfation | Metastases | Anticancer properties | Angiogenesis | Signaling | Chemotherapy | Sulfate resistance | Inhibitors | Antitumor agents | Heparan sulfate proteoglycans | Antitumor activity | Cancer
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3. Full Text G-quadruplex structures in the human genome as novel therapeutic targets
by Bidzinska, Joanna and Cimino-Reale, Graziella and Zaffaroni, Nadia and Folini, Marco
Molecules (Basel, Switzerland), ISSN 1420-3049, 10/2013, Volume 18, Issue 10, pp. 12368 - 12395
Telomeres | Small molecules | Oncogene | G-quadruplex | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Animals | Base Sequence | Humans | G-Quadruplexes | Antineoplastic Agents - pharmacology | Antineoplastic Agents - therapeutic use | Genome, Human | Molecular Targeted Therapy | Neoplasms - drug therapy | Telomere - genetics | Index Medicus | oncogene | small molecules | telomeres
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4. Full Text Targeting survivin in cancer therapy: fulfilled promises and open questions
by Pennati, Marzia and Folini, Marco and Zaffaroni, Nadia
Carcinogenesis (New York), ISSN 0143-3334, 6/2007, Volume 28, Issue 6, pp. 1133 - 1139
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Carcinogenesis, carcinogens and anticarcinogens | Medical sciences | Tumors | Neoplasms - metabolism | Inhibitor of Apoptosis Proteins | Microtubule-Associated Proteins - metabolism | Neoplasm Proteins - biosynthesis | Humans | Neoplasm Proteins - physiology | Neoplasm Proteins - antagonists & inhibitors | Biomarkers, Tumor - physiology | Microtubule-Associated Proteins - antagonists & inhibitors | Microtubule-Associated Proteins - biosynthesis | Neoplasm Proteins - metabolism | Drug Delivery Systems | Microtubule-Associated Proteins - physiology | Neoplasms - drug therapy | Animals | Biomarkers, Tumor - metabolism | Biomarkers, Tumor - antagonists & inhibitors | Neoplasms - pathology | Biomarkers, Tumor - biosynthesis | Index Medicus
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5. Full Text microRNAs as players and signals in the metastatic cascade: implications for the development of novel anti-metastatic therapies
by Gandellini, Paolo and Doldi, Valentina and Zaffaroni, Nadia
Seminars in cancer biology, ISSN 1044-579X, 2017, Volume 44, pp. 132 - 140
Hematology, Oncology and Palliative Medicine | Therapy | microRNA | Metastasis | Microenvironment | Extracellular | Life Sciences & Biomedicine | Oncology | Science & Technology | Neoplasm Metastasis - therapy | Humans | Neoplastic Cells, Circulating - metabolism | Signal Transduction - genetics | Biomarkers, Tumor - blood | Neoplasms - therapy | Neoplasms - blood | Tumor Microenvironment - genetics | Neoplasms - genetics | Neoplasm Metastasis - pathology | MicroRNAs - blood | MicroRNAs - genetics | Neoplasms - pathology | Gene Expression Regulation, Neoplastic - genetics | Proteins | MicroRNA | Genetic transcription | Analysis | Protein binding | Stem cells | Index Medicus
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6. Full Text The heparanase/heparan sulfate proteoglycan axis: a potential new therapeutic target in sarcomas
by Cassinelli, Giuliana and Zaffaroni, Nadia and Lanzi, Cinzia
Cancer letters, ISSN 0304-3835, 2016, Volume 382, Issue 2, pp. 245 - 254
Hematology, Oncology and Palliative Medicine | Heparanase | Sarcoma | Heparan sulfate mimetic | Heparanase inhibitor | Heparan sulfate proteoglycan | Life Sciences & Biomedicine | Oncology | Science & Technology | Enzyme Inhibitors - adverse effects | Humans | Glucuronidase - metabolism | Drug Discovery - methods | Heparin - therapeutic use | Sarcoma - enzymology | Antineoplastic Agents - therapeutic use | Heparin - adverse effects | Molecular Targeted Therapy | Sarcoma - drug therapy | Sarcoma - pathology | Enzyme Inhibitors - therapeutic use | Molecular Mimicry | Animals | Heparin - analogs & derivatives | Signal Transduction - drug effects | Antineoplastic Agents - adverse effects | Heparan Sulfate Proteoglycans - metabolism | Glucuronidase - antagonists & inhibitors | Development and progression | Deregulation | Sulfates | Health aspects | Index Medicus
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7. Full Text LEADeR role of miR-205 host gene as long noncoding RNA in prostate basal cell differentiation
by mo, Valentina and Forte, Barbara and Percio, Stefano and Rotundo, Federica and Doldi, Valentina and Ferrari, Elena and Fenderico, Nicola and Dugo, Matteo and Romagnoli, Dario and Benelli, Matteo and Valdagni, Riccardo and Dolfini, Diletta and Zaffaroni, Nadia and Gandellini, Paolo
Nature communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 307 - 307
Chemistry(all) | Biochemistry, Genetics and Molecular Biology(all) | Physics and Astronomy(all) | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Promoter Regions, Genetic | Epithelial Cells - metabolism | Ribonuclease III - metabolism | Humans | Cells, Cultured | Transcriptome | Male | RNA, Long Noncoding - genetics | Gene Editing | Prostate - metabolism | CRISPR-Cas Systems | Prostate - cytology | Cell Line, Tumor | Cell Differentiation | MicroRNAs - genetics | Protein kinase A | Calcium | Kinases | Substrates | Erythrocytes | Index Medicus
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