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Nature Genetics, ISSN 1061-4036, 07/2016, Volume 48, Issue 7, pp. 768 - 776
Glioblastoma (GBM) is the most common and aggressive primary brain tumor. To better understand how GBM evolves, we analyzed longitudinal genomic and... 
GENE FUSIONS | TGF-BETA | CANCER GENOMICS | LANDSCAPE | GLIOMA | GENETICS & HEREDITY | GENOMIC ALTERATIONS | MSH6 MUTATIONS | SEQUENCING DATA | BRAIN-TUMORS | TEMOZOLOMIDE | Cell Proliferation | Dacarbazine - therapeutic use | Genomics | Humans | Brain Neoplasms - pathology | DNA Repair Enzymes - genetics | Gene Expression Regulation, Neoplastic | Transcriptome | Neoplasm Recurrence, Local - drug therapy | Clonal Evolution - genetics | Neoplasm Recurrence, Local - pathology | Neoplasm Grading | Glioblastoma - genetics | Tumor Suppressor Proteins - genetics | Dacarbazine - analogs & derivatives | Brain Neoplasms - genetics | Isocitrate Dehydrogenase - genetics | Survival Rate | Brain Neoplasms - drug therapy | Mutation - genetics | Antineoplastic Agents, Alkylating - therapeutic use | Latent TGF-beta Binding Proteins - genetics | DNA Modification Methylases - genetics | Transforming Growth Factor beta - genetics | Glioblastoma - pathology | Neoplasm Recurrence, Local - genetics | Biomarkers, Tumor - genetics | Glioblastoma - drug therapy | Longitudinal Studies | Molecular targeted therapy | Care and treatment | Gene mutations | Development and progression | Genetic aspects | Genetic transcription | Glioblastoma multiforme | Health aspects | Methods | Brain cancer | Genomes | Gene expression | Cancer therapies | Studies | Archives & records | DNA methylation | Mathematical models | Mutation | Deoxyribonucleic acid--DNA | Tumors | Cancer | Index Medicus
Journal Article
01/2018, ISBN 0355665271
Many problems in the biological sciences reduce to questions of genetic evolution. Entire classes of medical pathology, such as malignant neoplasia or... 
Genetics | Applied Mathematics | Bioinformatics
Dissertation
Molecular Cancer Research, ISSN 1541-7786, 08/2017, Volume 15, Issue 8, pp. 1051 - 1062
TP53 is the most commonly mutated tumor suppressor gene and its mutation drives tumorigenesis. Using ChIP-seq for p53 in the absence of acute cell stress, we... 
APOPTOSIS | CANCER GENES | ONCOLOGY | PATHWAY | HUMAN-CELLS | SUSCEPTIBILITY | PROTEIN P53 | MICE | BINDING | GENOME | HAPLOINSUFFICIENCY | CELL BIOLOGY | Haploinsufficiency - genetics | PTEN Phosphohydrolase - genetics | Humans | Gene Expression Regulation, Neoplastic | Protein-Serine-Threonine Kinases - genetics | Signal Transduction - genetics | Binding Sites - genetics | Histone Demethylases - genetics | Tumor Suppressor Protein p53 - genetics | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Tumor Suppressor Proteins - genetics | Cell Line, Tumor | Protein Binding | MicroRNAs - genetics | Receptors, TNF-Related Apoptosis-Inducing Ligand - genetics | Mutation | Neoplasms - pathology | Nuclear Proteins - genetics | Forkhead Box Protein O1 - genetics | Stresses | Transformation | p53 Protein | Genes | Gene deletion | Gene expression | Stress | LKB1 protein | Enhancers | Reporter gene | Clonal deletion | FOXO1 protein | Deletion | Tumor suppressor genes | Tumorigenesis | Binding sites | PTEN protein | Cancer | Index Medicus | tumor suppression | enhancer analysis | transcriptional regulation | other tumor suppressor genes | PTEN | promoter | p53 | Medicinsk genetik | Basic Medicine | Medical Genetics | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin | Cancer and Oncology | Cancer och onkologi
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 01/2016, Volume 76, Issue 2 Supplement, pp. A24 - A24
Journal Article
Biochemistry, ISSN 0006-2960, 02/2019, Volume 58, Issue 8, pp. 1167 - 1178
RNA signals located downstream of stop codons in eukaryotic mRNAs can stimulate high levels of translational readthrough by the ribosome, thereby giving rise... 
TRANSLATIONAL TERMINATION EFFICIENCY | NUCLEOTIDES | IMPACT | EVOLUTION | SEQUENCES | MECHANISM | DOWNSTREAM | BIOCHEMISTRY & MOLECULAR BIOLOGY | READ-THROUGH | PSEUDOKNOT | FUSIONS
Journal Article
PLoS Pathogens, ISSN 1553-7366, 10/2015, Volume 11, Issue 10
  Endemic Burkitt lymphoma (eBL) is primarily found in children in equatorial regions and represents the first historical example of a virus-associated human... 
Cytomegalovirus | Malaria | Cell cycle | Lymphomas | Infections | Mutation | Tumors
Journal Article
Blood, ISSN 0006-4971, 2016, Volume 128, Issue 10, pp. 1362 - 1373
Journal Article
by Hill, Steven M and Heiser, Laura M and Cokelaer, Thomas and Linger, Michael and Nesser, Nicole K and Carlin, Daniel E and Zhang, Yang and Sokolov, Artem and Paull, Evan O and Wong, Chris K and Graim, Kiley and Bivol, Adrian and Wang, Haizhou and Zhu, Fan and Afsari, Bahman and Danilova, Ludmila V and Favorov, Alexander V and Lee, Wai Shing and Taylor, Dane and Hu, Chenyue W and Long, Byron L and Noren, David P and Bisberg, Alexander J and Mills, Gordon B and Gray, Joe W and Kellen, Michael and Norman, Thea and Friend, Stephen and Qutub, Amina A and Fertig, Elana J and Guan, Yuanfang and Song, Mingzhou and Stuart, Joshua M and Spellman, Paul T and Koeppl, Heinz and Stolovitzky, Gustavo and Saez-Rodriguez, Julio and Mukherjee, Sach and Al-Ouran, Rami and Anton, Bernat and Arodz, Tomasz and Sichani, Omid Askari and Bagheri, Neda and Berlow, Noah and Bohler, Anwesha and Bonet, Jaume and Bonneau, Richard and Budak, Gungor and Bunescu, Razvan and Caglar, Mehmet and Cai, Binghuang and Cai, Chunhui and Carlon, Azzurra and Chen, Lujia and Ciaccio, Mark F and Cooper, Gregory and Coort, Susan and Creighton, Chad J and Daneshmand, Seyed-Mohammad-Hadi and De La Fuente, Alberto and Di Camillo, Barbara and Dutta-Moscato, Joyeeta and Emmett, Kevin and Evelo, Chris and Fassia, Mohammad-Kasim H and Finotello, Francesca and Finkle, Justin D and Gao, Xi and Garcia-Garcia, Javier and Ghosh, Samik and Giaretta, Alberto and Großeholz, Ruth and Guinney, Justin and Hafemeister, Christoph and Hahn, Oliver and Haider, Saad and Hase, Takeshi and Hodgson, Jay and Hoff, Bruce and Hsu, Chih Hao and Hu, Ying and Huang, Xun and Jalili, Mahdi and Jiang, Xia and Kacprowski, Tim and Kaderali, Lars and Kang, Mingon and Kannan, Venkateshan and Kikuchi, Kaito and Kim, Dong-Chul and Kitano, Hiroaki and Knapp, Bettina and Komatsoulis, George and Krämer, Andreas and Kursa, Miron Bartosz and Kutmon, Martina and Li, Yichao and Liang, Xiaoyu and Liu, Zhaoqi and Liu, Yu and ... and HPN-DREAM Consortium and The HPN-DREAM Consortium
Nature Methods, ISSN 1548-7091, 03/2016, Volume 13, Issue 4, pp. 310 - 322
Journal Article