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animals (12) 12
index medicus (12) 12
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signal transduction (7) 7
vascular endothelial growth factor (7) 7
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vascular endothelial growth factor a - genetics (4) 4
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abridged index medicus (3) 3
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medicine, research & experimental (3) 3
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neovascularization, pathologic (3) 3
neovascularization, pathologic - metabolism (3) 3
neovascularization, physiologic (3) 3
receptors, notch - metabolism (3) 3
retinal vessels - metabolism (3) 3
tumors (3) 3
vascular endothelial growth factor receptor-3 - metabolism (3) 3
angiogenesis inhibitors - pharmacology (2) 2
antigens, cd - metabolism (2) 2
article (2) 2
blood vessels - growth & development (2) 2
cadherin (2) 2
cadherins - metabolism (2) 2
cell biology (2) 2
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cell line, tumor (2) 2
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in-vivo (2) 2
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intestine (2) 2
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Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 11/2015, Volume 7, Issue 11, pp. 1418 - 1425
Journal Article
Nature, ISSN 0028-0836, 07/2008, Volume 454, Issue 7204, pp. 656 - 660
Journal Article
Nature Cell Biology, ISSN 1465-7392, 10/2011, Volume 13, Issue 10, pp. 1202 - 1213
Angiogenesis, the growth of new blood vessels, involves specification of endothelial cells to tip cells and stalk cells, which is controlled by Notch... 
LYMPHATIC ENDOTHELIUM | KINASE-ACTIVITY | VASCULAR NETWORK FORMATION | ENDOTHELIAL-GROWTH-FACTOR | FACTOR-C | MOUSE EMBRYOS | EXTRACELLULAR-MATRIX | MONOCLONAL-ANTIBODY | TUMOR ANGIOGENESIS | FACTOR RECEPTOR-3 | CELL BIOLOGY | Neovascularization, Physiologic - drug effects | Human Umbilical Vein Endothelial Cells - metabolism | Receptors, Notch - metabolism | Humans | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Receptors, Notch - antagonists & inhibitors | Transfection | RNA Interference | Time Factors | Forkhead Transcription Factors - metabolism | Vascular Endothelial Growth Factor D - genetics | Phosphatidylinositol 3-Kinase - metabolism | Vascular Endothelial Growth Factor Receptor-3 - deficiency | Transduction, Genetic | Retinal Vessels - metabolism | Endothelial Cells - metabolism | Rhombencephalon - blood supply | Gene Expression Regulation | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Forkhead Transcription Factors - genetics | Vascular Endothelial Growth Factor C - genetics | Mice, Knockout | Antibodies - pharmacology | Macrophages - metabolism | Vascular Endothelial Growth Factor D - metabolism | Animals | Signal Transduction - drug effects | Vascular Endothelial Growth Factor B - metabolism | Vascular Endothelial Growth Factor C - metabolism | Cell Line, Tumor | Neovascularization, Pathologic - genetics | Vascular Endothelial Growth Factor B - genetics | Mice | Neovascularization, Pathologic - metabolism | Protein Kinase Inhibitors - pharmacology | Vascular Endothelial Growth Factor Receptor-3 - genetics | Endothelial Cells - drug effects | Physiological aspects | Blood vessels | Cellular signal transduction | Growth factor receptors | Research | Vascular endothelial growth factor | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2014, Volume 124, Issue 9, pp. 3975 - 3986
Journal Article
Circulation Research, ISSN 0009-7330, 04/2017, Volume 120, Issue 9, pp. 1414 - 1425
RATIONALE:Vascular endothelial growth factor (VEGF) is the main driver of angiogenesis and vascular permeability via VEGF receptor 2 (VEGFR2), whereas... 
Blood vessels | vascular leakage | VE-Cadherin | vascular biology | VEGF receptor regulation | REGRESSION | LYMPHATIC ENDOTHELIUM | CARDIAC & CARDIOVASCULAR SYSTEMS | RECEPTOR VEGFR-3 | ANGIOGENESIS | ENDOTHELIAL-GROWTH-FACTOR | FACTOR-C | MOUSE EMBRYOS | blood vessels | IN-VIVO | PERIPHERAL VASCULAR DISEASE | ADHERENS JUNCTIONS | HEMATOLOGY | Cadherins - metabolism | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Neovascularization, Pathologic | Capillary Permeability - drug effects | Male | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Carcinoma, Lewis Lung - blood supply | Adherens Junctions - metabolism | Antigens, CD - metabolism | Vascular Endothelial Growth Factor Receptor-2 - genetics | Transfection | Female | Vascular Endothelial Growth Factor A - pharmacology | Tight Junctions - metabolism | Vascular Endothelial Growth Factor Receptor-3 - deficiency | Retinal Vessels - metabolism | Endothelial Cells - metabolism | Mice, Inbred C57BL | Vascular Endothelial Growth Factor Receptor-2 - deficiency | Cells, Cultured | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Genotype | Retinal Vessels - drug effects | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Carcinoma, Lewis Lung - metabolism | Mice, Knockout | Phenotype | Animals | Signal Transduction - drug effects | Lung - blood supply | Neovascularization, Physiologic | Vascular Endothelial Growth Factor Receptor-3 - genetics | Endothelial Cells - drug effects | Leakage | Phosphorylation | Kidneys | Cell junctions | Permeability | Gene deletion | Cadherin | Endothelial cells | Vascular endothelial growth factor receptors | Gene silencing | Angiogenesis | Clonal deletion | Rodents | Fibrinogen | Localization | Vascular endothelial growth factor | Tumors
Journal Article
Science, ISSN 0036-8075, 08/2018, Volume 361, Issue 6402, pp. 599 - 603
Excess dietary lipid uptake causes obesity, a major global health problem. Enterocyte-absorbed lipids are packaged into chylomicrons, which enter the... 
TRANSPORT | ANGIOGENESIS | INTEGRITY | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | ENDOTHELIAL-CELLS | GROWTH | VEGF-C | MECHANISMS | CHYLOMICRONS | LIPOPROTEINS | Neuropilin-1 - genetics | Dietary Fats - metabolism | Cadherins - metabolism | Enterocytes - metabolism | Diet, High-Fat - adverse effects | Male | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Obesity - genetics | Antigens, CD - metabolism | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | Gene Deletion | Obesity - etiology | Intestinal Absorption - physiology | Vascular Endothelial Growth Factor Receptor-1 - genetics | Dietary Fats - adverse effects | Chylomicrons - adverse effects | Signal Transduction | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Mice, Knockout | Chylomicrons - metabolism | Animals | Intestinal Absorption - genetics | Cadherins - antagonists & inhibitors | Mice | Prevention | Dietary fat | Physiological aspects | Obesity | Metabolism | Health aspects | Neuropilin | Lipids | High fat diet | Receptors | Clonal deletion | Intestine | Rodents | Deletion | Malabsorption | Vascular endothelial growth factor | Growth factors | Public health | Lymphatic system | Blood vessels | Chylomicrons | Bioavailability | Cadherin | Endothelial cells | Anchors | Signaling | Diet | Cytoskeleton | Fats | Transport | Dismantling
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 02/2014, Volume 124, Issue 2, pp. 824 - 834
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2015, Volume 112, Issue 3, p. 761
  Angiogenesis, the formation of new blood vessels, is regulated by vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs). VEGFR2 is... 
Angiogenesis | Signal transduction | Blood vessels | Vascular endothelial growth factor | Cells
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 03/2012, Volume 104, Issue 6, pp. 461 - 475
Background Angiopoietin-2 (Ang2), a ligand for endothelial TEK (Tie2) tyrosine kinase receptor, is induced in hypoxic endothelial cells of tumors, where it... 
LYMPHATIC VESSELS | TRANSGENE EXPRESSION | ANGIOGENESIS | ONCOLOGY | IN-VIVO | GENE-THERAPY | VEGF-C | TUMOR-GROWTH | CANCER | RECEPTOR TYROSINE KINASE | TIE2 RECEPTOR | Immunohistochemistry | Antibodies, Blocking - metabolism | Up-Regulation | Immunoprecipitation | Melanoma - blood supply | Coculture Techniques | Endothelium, Vascular - drug effects | Immunoblotting | Transplantation, Heterologous | Antibodies, Blocking - pharmacology | Angiopoietin-2 - metabolism | Cell Hypoxia | Retinal Vessels - pathology | Lung Neoplasms - secondary | Intercellular Junctions - pathology | Female | Neovascularization, Pathologic - prevention & control | Receptor, TIE-2 - metabolism | Lymphangiogenesis | Lung Neoplasms - blood supply | Microscopy, Electron, Transmission | Retinal Vessels - metabolism | Intercellular Junctions - metabolism | Angiogenesis Inhibitors - pharmacology | Mice, Transgenic | Lymphatic Metastasis | Retinal Vessels - drug effects | Mice, SCID | Melanoma - secondary | Animals | Neovascularization, Pathologic - drug therapy | Intercellular Junctions - drug effects | Endothelium, Vascular - pathology | Mice | Mice, Inbred BALB C | Neovascularization, Pathologic - metabolism | Angiopoietin-2 - antagonists & inhibitors | Endothelial Cells - pathology | Endothelial Cells - drug effects | Junctional complexes (Epithelium) | Lung cancer | Cell junctions | Physiological aspects | Development and progression | Models | Metastasis | Research | Growth factor receptors
Journal Article
Development (Cambridge), ISSN 0950-1991, 04/2013, Volume 140, Issue 7, pp. 1497 - 1506
Journal Article
Science Signaling, ISSN 1945-0877, 07/2013, Volume 6, Issue 282, pp. ra52 - ra52
Vascular endothelial growth factors (VEGFs) regulate blood and lymphatic vessel development through VEGF receptors (VEGFRs). The VEGFR immunoglobulin homology... 
SIGNAL-TRANSDUCTION | ACTIVATION | IMMUNOGLOBULIN-LIKE DOMAIN | FACTOR-B | STRUCTURAL BASIS | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | FACTOR VEGF FAMILY | PATHOLOGICAL ANGIOGENESIS | BINDING | CELL BIOLOGY | NIH 3T3 Cells | Pregnancy Proteins - chemistry | Phosphorylation | Humans | Pregnancy Proteins - genetics | Molecular Sequence Data | Pregnancy Proteins - metabolism | Vascular Endothelial Growth Factor A - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Vascular Endothelial Growth Factor A - genetics | Vascular Endothelial Growth Factor Receptor-2 - genetics | Vascular Endothelial Growth Factor A - chemistry | Vascular Endothelial Growth Factor B - chemistry | Female | Vascular Endothelial Growth Factor Receptor-1 - genetics | Binding, Competitive | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Signal Transduction | Cells, Cultured | Models, Molecular | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Binding Sites - genetics | Vascular Endothelial Growth Factor Receptor-1 - chemistry | Blotting, Western | Sequence Homology, Amino Acid | Vascular Endothelial Growth Factor Receptor-2 - chemistry | Animals | Vascular Endothelial Growth Factor B - metabolism | Placenta Growth Factor | Protein Binding | Ligands | Vascular Endothelial Growth Factor B - genetics | Mice
Journal Article
Blood, ISSN 0006-4971, 08/2013, Volume 122, Issue 5, pp. 658 - 665
Journal Article