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Nature cell biology, ISSN 1476-4679, 09/2011, Volume 13, Issue 10, pp. 1202 - 1213
Angiogenesis, the growth of new blood vessels, involves specification of endothelial cells to tip cells and stalk cells, which is controlled by Notch... 
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neovascularization, Physiologic - drug effects | Human Umbilical Vein Endothelial Cells - metabolism | Receptors, Notch - metabolism | Humans | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Receptors, Notch - antagonists & inhibitors | Transfection | RNA Interference | Time Factors | Forkhead Transcription Factors - metabolism | Vascular Endothelial Growth Factor D - genetics | Phosphatidylinositol 3-Kinase - metabolism | Vascular Endothelial Growth Factor Receptor-3 - deficiency | Transduction, Genetic | Retinal Vessels - metabolism | Endothelial Cells - metabolism | Rhombencephalon - blood supply | Gene Expression Regulation | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Forkhead Transcription Factors - genetics | Vascular Endothelial Growth Factor C - genetics | Mice, Knockout | Antibodies - pharmacology | Macrophages - metabolism | Vascular Endothelial Growth Factor D - metabolism | Animals | Signal Transduction - drug effects | Vascular Endothelial Growth Factor B - metabolism | Vascular Endothelial Growth Factor C - metabolism | Cell Line, Tumor | Neovascularization, Pathologic - genetics | Vascular Endothelial Growth Factor B - genetics | Mice | Neovascularization, Pathologic - metabolism | Protein Kinase Inhibitors - pharmacology | Vascular Endothelial Growth Factor Receptor-3 - genetics | Endothelial Cells - drug effects | Physiological aspects | Blood vessels | Cellular signal transduction | Growth factor receptors | Research | Vascular endothelial growth factor | Index Medicus
Journal Article
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 01/2014, Volume 124, Issue 2, pp. 824 - 834
Journal Article
Nature (London), ISSN 1476-4687, 06/2008, Volume 454, Issue 7204, pp. 656 - 660
Journal Article
Journal Article
Circulation research, ISSN 1524-4571, 04/2017, Volume 120, Issue 9, pp. 1414 - 1425
RATIONALE:Vascular endothelial growth factor (VEGF) is the main driver of angiogenesis and vascular permeability via VEGF receptor 2 (VEGFR2), whereas... 
Blood vessels | vascular leakage | VE-Cadherin | vascular biology | VEGF receptor regulation | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Cadherins - metabolism | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Neovascularization, Pathologic | Capillary Permeability - drug effects | Male | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Carcinoma, Lewis Lung - blood supply | Adherens Junctions - metabolism | Antigens, CD - metabolism | Vascular Endothelial Growth Factor Receptor-2 - genetics | Transfection | Female | Vascular Endothelial Growth Factor A - pharmacology | Tight Junctions - metabolism | Vascular Endothelial Growth Factor Receptor-3 - deficiency | Retinal Vessels - metabolism | Endothelial Cells - metabolism | Mice, Inbred C57BL | Vascular Endothelial Growth Factor Receptor-2 - deficiency | Cells, Cultured | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Genotype | Retinal Vessels - drug effects | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Carcinoma, Lewis Lung - metabolism | Mice, Knockout | Phenotype | Animals | Signal Transduction - drug effects | Lung - blood supply | Neovascularization, Physiologic | Vascular Endothelial Growth Factor Receptor-3 - genetics | Endothelial Cells - drug effects | Leakage | Phosphorylation | Kidneys | Cell junctions | Permeability | Gene deletion | Cadherin | Endothelial cells | Vascular endothelial growth factor receptors | Gene silencing | Angiogenesis | Clonal deletion | Rodents | Fibrinogen | Localization | Vascular endothelial growth factor | Tumors | Index Medicus | blood vessels
Journal Article
JNCI : Journal of the National Cancer Institute, ISSN 1460-2105, 03/2012, Volume 104, Issue 6, pp. 461 - 475
Background Angiopoietin-2 (Ang2), a ligand for endothelial TEK (Tie2) tyrosine kinase receptor, is induced in hypoxic endothelial cells of tumors, where it... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Immunohistochemistry | Antibodies, Blocking - metabolism | Up-Regulation | Immunoprecipitation | Melanoma - blood supply | Coculture Techniques | Endothelium, Vascular - drug effects | Immunoblotting | Transplantation, Heterologous | Antibodies, Blocking - pharmacology | Angiopoietin-2 - metabolism | Cell Hypoxia | Retinal Vessels - pathology | Lung Neoplasms - secondary | Intercellular Junctions - pathology | Female | Neovascularization, Pathologic - prevention & control | Receptor, TIE-2 - metabolism | Lymphangiogenesis | Lung Neoplasms - blood supply | Microscopy, Electron, Transmission | Retinal Vessels - metabolism | Intercellular Junctions - metabolism | Angiogenesis Inhibitors - pharmacology | Mice, Transgenic | Lymphatic Metastasis | Retinal Vessels - drug effects | Mice, SCID | Melanoma - secondary | Animals | Neovascularization, Pathologic - drug therapy | Intercellular Junctions - drug effects | Endothelium, Vascular - pathology | Mice | Mice, Inbred BALB C | Neovascularization, Pathologic - metabolism | Angiopoietin-2 - antagonists & inhibitors | Endothelial Cells - pathology | Endothelial Cells - drug effects | Junctional complexes (Epithelium) | Lung cancer | Cell junctions | Physiological aspects | Development and progression | Models | Metastasis | Research | Growth factor receptors | Studies | Lungs | Medical treatment | Tumors | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 08/2013, Volume 122, Issue 5, pp. 658 - 665
Journal Article