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PLoS ONE, ISSN 1932-6203, 10/2015, Volume 10, Issue 10, pp. e0139950 - e0139950
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2018, Volume 13, Issue 9, pp. e0203398 - e0203398
Objectives Spinal muscular atrophy (SMA) is a devastating motor neuron disorder caused by homozygous loss of the survival motor neuron 1 (SMN1) gene and... 
RHEUMATOID-ARTHRITIS | SURVIVAL | GENE | FATTY LIVER-DISEASE | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | IMPAIRED ENDOCYTOSIS | SERUM FETUIN | OLIGOMERIC MATRIX PROTEIN | MOTOR-NEURON PROTEIN | CARTILAGE | Biomarkers - metabolism | Muscular Atrophy, Spinal - metabolism | Oligodeoxyribonucleotides, Antisense - pharmacology | Membrane Glycoproteins - biosynthesis | Muscular Atrophy, Spinal - pathology | Membrane Glycoproteins - genetics | Mice, Knockout | Gene Expression Regulation - drug effects | Muscular Atrophy, Spinal - genetics | Microfilament Proteins - biosynthesis | Animals | Survival of Motor Neuron 1 Protein - antagonists & inhibitors | Muscular Atrophy, Spinal - therapy | Survival of Motor Neuron 1 Protein - genetics | Mice | Survival of Motor Neuron 1 Protein - biosynthesis | Microfilament Proteins - genetics | Research | Biological markers | Gene expression | Drug therapy | Spinal muscular atrophy | Therapy | Immunoassay | SMN protein | Oligonucleotides | Vitronectin | Motors | Feasibility analysis | Cartilage oligomeric matrix protein | Proteins | Atrophy | Cartilage | Biomedical materials | Genetics | Biocompatibility | Bioindicators | Matrix protein | Phenotypes | Liver diseases | Peptidase | Cell survival | Glycoprotein | Feasibility studies | Osteopontin | Antisense oligonucleotides | Medicine | Medical prognosis | Biomarkers | Alzheimers disease | Index Medicus
Journal Article
Annals of Neurology, ISSN 0364-5134, 12/2017, Volume 82, Issue 6, pp. 883 - 891
Journal Article
HUMAN MOLECULAR GENETICS, ISSN 0964-6906, 10/2015, Volume 24, Issue 19, pp. 5524 - 5541
Proximal spinal muscular atrophy (SMA) is the most frequent cause of hereditary infant mortality. SMA is an autosomal recessive neuromuscular disorder that... 
SURVIVAL | PROTEIN | SPINAL MUSCULAR-ATROPHY | BIOCHEMISTRY & MOLECULAR BIOLOGY | COPY NUMBER | GENETICS & HEREDITY | DETERMINING GENE | MICE | CARDIAC DEFECTS | NEUROMUSCULAR-JUNCTIONS | SINGLE NUCLEOTIDE | CEREBRAL-CORTEX
Journal Article
Journal Article
PloS one, 2014, Volume 9, Issue 10, p. e111428
There is a need for better, noninvasive quantitative biomarkers for assessing the rate of progression and possible response to therapy in spinal muscular... 
Action Potentials | Muscular Atrophy, Spinal - diagnosis | Animals | Muscle, Skeletal - physiopathology | Muscle, Skeletal - innervation | Mice | Electromyography - methods | Muscular Atrophy, Spinal - physiopathology
Journal Article
PLoS ONE, 10/2015, Volume 10, Issue 10
Spinal muscular atrophy is caused by a functional deletion of SMN1 on Chromosome 5, which leads to a progressive loss of motor function in affected patients.... 
Journal Article
Journal of Biomolecular Screening, ISSN 1087-0571, 08/2002, Volume 7, Issue 4, pp. 359 - 366
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 1999, Volume 128, Issue 6, pp. 1181 - 1188
1 The D3 dopamine receptor presumably activates G(i)/G(o) subtypes of G-proteins, like the structurally analogous D2 receptor, but its signalling targets have... 
G(o) subtypes of G-proteins | Signalling of D3 dopamine receptor | GTP | S bound Gα subunits | Human D3 dopamine receptor | SH-SY5Y cells | STIMULATION | GTPS bound G alpha subunits | CURRENTS | INHIBITION | D-3 RECEPTOR | CLONING | ADENYLYL-CYCLASE | LINE | GAMMA-S BINDING | PITUITARY-CELLS | signalling of D3 dopamine receptor | PHARMACOLOGY & PHARMACY | human D3 dopamine receptor | EXPRESSION | Calcium Channels - metabolism | Humans | Recombinant Fusion Proteins - physiology | Tritium | Receptors, Dopamine D2 - metabolism | GTP-Binding Proteins - genetics | Recombinant Fusion Proteins - metabolism | RNA - genetics | Dose-Response Relationship, Drug | Radioligand Assay | Tumor Cells, Cultured | Cyclic AMP - metabolism | Dopamine Agonists - metabolism | RNA - metabolism | Calcium Channels - drug effects | Membrane Potentials - drug effects | Cell Line | Dopamine Agonists - pharmacology | Colforsin - pharmacology | Sulfur Radioisotopes | Reverse Transcriptase Polymerase Chain Reaction | Receptors, Dopamine D2 - genetics | Binding, Competitive - drug effects | Guanosine 5'-O-(3-Thiotriphosphate) - metabolism | Quinpirole - metabolism | Receptors, Dopamine D3 | Recombinant Fusion Proteins - genetics | Receptors, Dopamine D2 - physiology | Quinpirole - pharmacology | Adenylyl Cyclases - genetics | GTP-Binding Proteins - metabolism | Index Medicus
Journal Article