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2013, Colloquium series on the genetic basis of human disease, ISBN 9781615044269, Volume 3
Web Resource
2013, Colloquium digital library of life sciences;Colloquium series on the genetic basis of human disease, ISBN 9781615044269, 88
I had the good fortune to work at the National Cancer Institute from 1965 to 2005. The National Cancer Institute provided an environment that permitted my... 
Life Sciences | Genetics & Genomics | SCIENCE | Genetic aspects | Renal cell carcinoma | Immunotherapy | Cancer
eBook
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2006, Volume 103, Issue 42, pp. 15552 - 15557
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 1/2008, Volume 100, Issue 2, pp. 140 - 154
Background Patients with Birt-Hogg-Dubé (BHD) syndrome harbor germline mutations in the BHD tumor suppressor gene that are associated with an increased risk... 
COLLECTING DUCT | TUBEROUS SCLEROSIS COMPLEX | ONCOLOGY | GERMAN-SHEPHERD DOG | INTERCALATED CELLS | BHD GENE | CANCER | RENAL-CARCINOMA | GENITOURINARY TRACT | RAT MODEL | NODULAR DERMATOFIBROSIS | Immunohistochemistry | Polycystic Kidney Diseases - genetics | Protein Kinases - metabolism | Blotting, Southern | Kidney Neoplasms - genetics | Antibiotics, Antineoplastic - pharmacology | Kidney - pathology | Immunoblotting | Kidney Neoplasms - metabolism | Mitogen-Activated Protein Kinase 1 - drug effects | Polycystic Kidney Diseases - complications | Mitogen-Activated Protein Kinase 3 - drug effects | Kidney - metabolism | Polycystic Kidney Diseases - pathology | Tumor Suppressor Proteins - genetics | Germ-Line Mutation | Disease Models, Animal | Estrone - genetics | Polycystic Kidney Diseases - metabolism | Protein Kinases - drug effects | Kidney - drug effects | Gene Silencing | Kaplan-Meier Estimate | Genotype | Proto-Oncogene Proteins - genetics | Random Allocation | Reverse Transcriptase Polymerase Chain Reaction | Sirolimus - pharmacology | Syndrome | Mice, Knockout | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Signal Transduction - drug effects | Fluorescent Antibody Technique | Kidney Neoplasms - pathology | Cell Proliferation - drug effects | Mice | TOR Serine-Threonine Kinases | Mitogen-Activated Protein Kinase 1 - metabolism | Cell proliferation | Gene silencing | Care and treatment | Kidney cancer | Physiological aspects | Genetic aspects | Research | Health aspects | Methods | Genetic disorders | Kidney diseases | Risk factors | Cancer | Tumors | Index Medicus
Journal Article
Human Mutation, ISSN 1059-7794, 09/2013, Volume 34, Issue 9, pp. 1231 - 1241
Journal Article
Journal of Urology, The, ISSN 0022-5347, 2012, Volume 188, Issue 6, pp. 2063 - 2071
Journal Article
Cancer Cell, ISSN 1535-6108, 2005, Volume 8, Issue 2, pp. 143 - 153
Individuals with hemizygous germline fumarate hydratase (FH) mutations are predisposed to renal cancer. These tumors predominantly exhibit functional... 
HYPOXIA-INDUCIBLE FACTOR | FACTOR 1-ALPHA | NUCLEAR TRANSLOCATOR ARNT | SUCCINATE-DEHYDROGENASE | ONCOLOGY | PROLYL HYDROXYLATION | TUMOR-SUPPRESSOR PROTEIN | HEREDITARY LEIOMYOMATOSIS | CELL-CANCER | HIPPEL-LINDAU PROTEIN | FAMILIAL PHEOCHROMOCYTOMA | CELL BIOLOGY | Up-Regulation | Kidney Neoplasms - genetics | Nuclear Proteins - analysis | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Leiomyomatosis - metabolism | Carcinoma, Renal Cell - genetics | DNA-Binding Proteins - analysis | Male | Kidney Neoplasms - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit | DNA-Binding Proteins - metabolism | Fumarate Hydratase - metabolism | Ketoglutaric Acids - pharmacology | Procollagen-Proline Dioxygenase - antagonists & inhibitors | Adult | Carcinoma, Renal Cell - enzymology | Female | Fumarate Hydratase - antagonists & inhibitors | Nuclear Proteins - genetics | Basic Helix-Loop-Helix Transcription Factors | Hypoxia-Inducible Factor 1 | Nuclear Proteins - metabolism | Fumarate Hydratase - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Syndrome | Transcription Factors - metabolism | Carcinoma, Renal Cell - metabolism | Fumarates - pharmacology | Kidney Neoplasms - enzymology | Alleles | Fumarates - metabolism | Transcription Factors - analysis | Leiomyomatosis - enzymology | Leiomyomatosis - genetics | Medical colleges | Hydroxylation | Pharmacy | Oncology, Experimental | Physiological aspects | Research | Cancer
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2001, Volume 98, Issue 13, pp. 7504 - 7509
Journal Article