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Journal Article
Nature Biotechnology, ISSN 1087-0156, 09/2009, Volume 27, Issue 9, pp. 851 - 857
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 6, pp. e21045 - e21045
Rabbits are widely used in biomedical research, yet techniques for their precise genetic modification are lacking. We demonstrate that zinc finger nucleases... 
PRION PROTEIN | PIGS | CELLS | MOUSE | BIOLOGY | GENERATION | MODEL | MONOCLONAL-ANTIBODIES | KNOCKOUT RATS | GENOME | TRANSGENIC MICE | Rabbits | Reproducibility of Results | Zinc Fingers | Microinjections | Protein Engineering - methods | Oocytes - metabolism | Humans | Immunoglobulin M - deficiency | RNA, Messenger - genetics | Genetic Loci - genetics | Molecular Sequence Data | Exons - genetics | Male | Gene Knockout Techniques | Mutation - genetics | Deoxyribonucleases - genetics | Animals | Immunoglobulin G - genetics | Base Sequence | Alleles | Female | Deoxyribonucleases - chemistry | Immunoglobulin M - genetics | Immunoglobulin M | Nucleases | Genetic vectors | RNA | Immunoglobulin G | Genes | Genetically modified organisms | Animal genetic engineering | B cells | DNA binding proteins | Zinc finger proteins | Health aspects | Biotechnology | Exons | Homologous recombination | Antibodies | Homology | Genomes | mRNA | Inactivation | Oocytes | Immunology | Cattle | Lymphocytes | Gene disruption | Coinjection | Experimentation | Genetic modification | Deoxyribonucleic acid--DNA | Polyclonal antibodies | Deactivation | Nucleotide sequence | Fetuses | Cloning | Artificial chromosomes | Gene expression | Embryos | Loci | Zinc | Offspring | Lymphocytes B | Mutagenesis | Livestock | Genetic engineering | Gene manipulation | Mutation | Gene therapy | Laboratory animals | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Plant Biotechnology Journal, ISSN 1467-7644, 12/2013, Volume 11, Issue 9, pp. 1126 - 1134
Journal Article
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 11/2004, Volume 167, Issue 4, pp. 583 - 590
Nucleocytoplasmic transport occurs through gigantic proteinaceous channels called nuclear pore complexes (NPCs). Translocation through the NPC is exquisitely... 
Yeasts | Nuclear pore | Receptors | Nuclear pore complex proteins | Messenger RNA | Architecture | Cell nucleus | Alleles | Reports | Imports | Freight | TRANSLOCATION | PROTEIN | AFFINITY | IMPORTIN-BETA | ARCHITECTURE | EXPORT | PROTEOMIC ANALYSIS | MICROSCOPY | GRADIENT | BINDING | CELL BIOLOGY | beta Karyopherins - genetics | Glycine - metabolism | Protein Binding - genetics | Saccharomyces cerevisiae - genetics | Cytoplasm - metabolism | RNA, Messenger - metabolism | Trinucleotide Repeats - genetics | Nuclear Pore Complex Proteins - genetics | Saccharomyces cerevisiae - metabolism | Membrane Transport Proteins - genetics | Membrane Transport Proteins - metabolism | Cytoplasm - genetics | Active Transport, Cell Nucleus - genetics | Nuclear Pore Complex Proteins - metabolism | Nuclear Pore - genetics | Receptors, Cytoplasmic and Nuclear - genetics | Binding Sites - genetics | Saccharomyces cerevisiae Proteins - genetics | Mutation - genetics | Nuclear Pore - metabolism | Protein Transport - genetics | Karyopherins - metabolism | Phenylalanine - genetics | Saccharomyces cerevisiae Proteins - metabolism | Karyopherins - genetics | beta Karyopherins - metabolism | Amino Acid Motifs - genetics | Receptors, Cytoplasmic and Nuclear - metabolism | Phenylalanine | Research | Proteins | Yeast | Mutation | Cellular biology | Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 07/2019, Volume 25, Issue 7, pp. 1131 - 1142
Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder caused by a CAG trinucleotide expansion in the huntingtin gene (HTT), which... 
Huntingtons disease | Brain | Transcription factors | Animal models | Polyglutamine | Huntingtin | Neurodegenerative diseases | Neurons | Medical treatment | Trinucleotide repeats | Gene expression | Huntington's disease | Zinc | Proteins | Gene silencing | Molecular modelling | Alleles | Fibroblasts | Zinc finger proteins | Trinucleotide repeat diseases
Journal Article