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Journal Article
Journal of Neuroscience, ISSN 0270-6474, 09/2010, Volume 30, Issue 36, pp. 11938 - 11950
Aggregation of amyloid-beta (A beta) and Tau protein are hallmarks of Alzheimer's disease (AD), and according to the A beta-cascade hypothesis, A beta is... 
AMYLOID-INDUCED NEURODEGENERATION | OXIDATIVE STRESS | PROTEIN OLIGOMERS | NEURITE OUTGROWTH | MECHANISM | ALZHEIMERS-DISEASE | AXONAL-TRANSPORT | PRECURSOR PROTEIN | NEUROTOXICITY | NEUROSCIENCES | CULTURED HIPPOCAMPAL-NEURONS
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2017, Volume 1523, pp. 327 - 334
Primary neurons have proved to be an invaluable tool for the investigation of Tau in the context of neuronal development and neurodegeneration. Culturing... 
NS21 | Primary neuronal cell culture | Polarity | Tau | Immunostaining | Animals | Cells, Cultured | Rats | tau Proteins - metabolism | Neurons - cytology | Neurons - metabolism | tau Proteins - analysis | Cell Culture Techniques - methods | Index Medicus
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2017, Volume 1523, pp. 335 - 340
Primary neurons have proved to be an essential tool for investigating neuronal polarity in general and polarized Tau distribution in particular. However,... 
Primary neuronal cell culture | Polarity | Tau | Transfection | Neurodegeneration | Microtubules - metabolism | Animals | Transfection - methods | Cells, Cultured | Cytoskeleton - metabolism | Rats | tau Proteins - metabolism | Neurons - metabolism | tau Proteins - analysis | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 29, pp. 12192 - 12207
Subcellular mislocalization of the microtubule-associated protein Tau is a hallmark of Alzheimer disease (AD) and other tauopathies. Six Tau isoforms,... 
DENDRITIC SPINES | NERVOUS-SYSTEM | PROTEIN-TAU | POLARIZED NEURONS | MICROTUBULES | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DIFFUSION BARRIER | MICE | HIPPOCAMPAL-NEURONS | EXPRESSION | Dendrites - pathology | Neurons - pathology | Rats, Wistar | Humans | Cerebral Cortex - pathology | tau Proteins - metabolism | Neurons - cytology | Cerebral Cortex - cytology | Recombinant Fusion Proteins - metabolism | Cerebral Cortex - metabolism | tau Proteins - chemistry | Alzheimer Disease - pathology | Microtubules - metabolism | Repetitive Sequences, Amino Acid | Axon Initial Segment - pathology | Protein Isoforms - metabolism | tau Proteins - genetics | RNA Interference | Protein Isoforms - chemistry | Gene Deletion | Neurons - metabolism | Protein Interaction Domains and Motifs | Diffusion | tau Proteins - antagonists & inhibitors | Dendrites - metabolism | Mice, Inbred C57BL | Cells, Cultured | Recombinant Fusion Proteins - chemistry | Microtubules - pathology | Mice, Knockout | Protein Transport | Axon Initial Segment - metabolism | Animals | Embryo, Mammalian - cytology | Alzheimer Disease - metabolism | Recombinant Fusion Proteins - genetics | Mutagenesis, Insertional | Protein Isoforms - antagonists & inhibitors | Protein Isoforms - genetics | Index Medicus | microtubule | tauopathy | Alzheimer disease | Tau protein (Tau) | neurodegeneration | cell polarity | AIS | amyloid-beta (Aβ) | Cell Biology
Journal Article
Neuro - Degenerative Diseases, ISSN 1660-2854, 04/2012, Volume 10, Issue 1-4, p. 64
  Background: In Alzheimer's disease (AD), amyloid-β (Aβ) is the major component of extracellular plaques, whereas the microtubule-associated protein tau forms... 
Journal Article
Neurodegenerative Diseases, ISSN 1660-2854, 2012, Volume 10, Issue 1-4, pp. 64 - 72
Journal Article
EMBO Journal, ISSN 0261-4189, 11/2013, Volume 32, Issue 22, p. 2920
  Mislocalization and aggregation of A[beta] and Tau combined with loss of synapses and microtubules (MTs) are hallmarks of Alzheimer disease. We exposed... 
Proteins | Neurodegeneration | Neurons | Alzheimers disease | Gene expression | Molecular biology
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 09/2010, Volume 30, Issue 36, pp. 11938 - 11950
Aggregation of amyloid-b (Ab) and Tau protein are hallmarks of Alzheimer's disease (AD), and according to the Ab-cascade hypothesis, Ab is considered toxic for... 
Journal Article
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2010, Volume 6, Issue 4, pp. S102 - S102
Journal Article
Biological & Pharmaceutical Bulletin, ISSN 0918-6158, 2010, Volume 33, Issue 1, pp. 22 - 28
We reported previously that N-linked glycoproteins were accumulated in the cytosol of the normal aging rat brain, and that one protein had been identified as... 
Journal Article
Neurodegenerative Diseases, ISSN 1660-2854, 04/2012, Volume 10, Issue 1-4, pp. 335 - 336
Journal Article