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Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 5272 - 5272
Abstract The IL7/IL7R mediated signaling is essential for normal development and homeostasis of T cell precursors. Early studies have shown that around 10% of... 
Journal Article
Nature Genetics, ISSN 1061-4036, 10/2011, Volume 43, Issue 10, pp. 932 - 941
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 06/2017, Volume 80, p. 95
Two activating mouse IgG receptors (Fc[gamma]Rs) have the ability to bind monomeric IgG, the high-affinity mouse Fc[gamma]RI and Fc[gamma]RIV. Despite high... 
Immunoglobulin G | Immunotherapy | Arthritis | Models | B cells | Analysis
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, p. e0134783
Acute Lymphoblastic Leukemia (ALL) is the most frequent childhood malignancy. In the effort to find new anti-leukemic agents, we evaluated the small drug... 
BREAST-CANCER CELLS | P53 TARGET GENE | NONPEPTIDE CXCR2 ANTAGONIST | KINASE-MEDIATED APOPTOSIS | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER | REPERFUSION INJURY | NF-KB | TUMOR-CELLS | STROMAL CELLS | EXPRESSION | Neoplasm Transplantation | Reactive Oxygen Species - metabolism | Oligonucleotide Array Sequence Analysis | Apoptosis - drug effects | Jurkat Cells | Humans | Gene Silencing | Mice, SCID | Nerve Tissue Proteins - drug effects | Blotting, Western | Neoplasm Proteins - drug effects | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Animals | Cell Line, Tumor | Mice, Inbred NOD | Antineoplastic Agents - pharmacology | Phenylurea Compounds - pharmacology | Cell Death - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Cell Cycle - drug effects | Real-Time Polymerase Chain Reaction | Biotechnology | Target recognition | Transcription | Downstream effects | Leukemia | Genomics | p53 Protein | Genes | Bladder | Lymphocytes T | Biology | Malignancy | Medical schools | Proteins | Antioxidants | Ethics | Tubulin | Transcription activation | Network analysis | Cell cycle | Inhibition | Pretreatment | Children | Bioinformatics | Acute lymphatic leukemia | CXCR2 protein | Breast cancer | Lymphatic leukemia | Gene expression | Urea | Lymphocytes B | Tumor necrosis factor | Cell death | Cell lines | Proteomics | Genetic engineering | Endoplasmic reticulum | Prostate cancer | Prostate | Apoptosis | Cancer
Journal Article
EBioMedicine, ISSN 2352-3964, 04/2018, Volume 30, pp. 158 - 166
The drug L-asparaginase is a cornerstone in the treatment of acute lymphoblastic leukemia (ALL). The native E. coli L-asparaginase used in Brazil until... 
Host contaminant proteins | Bioavailability | Immunogenicity | L-Asparaginase | Mass spectrometry | MEDICINE, RESEARCH & EXPERIMENTAL | IDENTIFICATION | CHILDHOOD | BRAZIL | CHILDREN | IMPACT | THERAPEUTIC PROTEINS | PART | ACUTE LYMPHOBLASTIC-LEUKEMIA
Journal Article
EBioMedicine, ISSN 2352-3964, 04/2018, Volume 30, pp. 158 - 166
The drug -asparaginase is a cornerstone in the treatment of acute lymphoblastic leukemia (ALL). The native -asparaginase used in Brazil until recently has been... 
Host contaminant proteins | l-Asparaginase | Bioavailability | Immunogenicity | Mass spectrometry
Journal Article
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