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Breast Cancer Research and Treatment, ISSN 0167-6806, 1/2007, Volume 101, Issue 1, pp. 113 - 121
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 12/2003, Volume 95, Issue 23, pp. 1758 - 1764
Background: Tamoxifen, a selective estrogen receptor modulator (SERM), is converted to 4-hydroxy-tamoxifen and other active metabolites by cytochrome P450... 
PERFORMANCE LIQUID-CHROMATOGRAPHY | BREAST-CANCER | MAJOR METABOLITES | ONCOLOGY | 4-HYDROXYLATION | RANDOMIZED CONTROLLED-TRIAL | HUMAN LIVER-MICROSOMES | CYP2D6 ACTIVITY | HOT FLASHES | CYTOCHROME-P450 2D6 | VENLAFAXINE | Cytochrome P-450 CYP2D6 Inhibitors | Paroxetine - pharmacokinetics | Serotonin Uptake Inhibitors - pharmacokinetics | Prospective Studies | Cytochrome P-450 Enzyme Inhibitors | Selective Estrogen Receptor Modulators - pharmacokinetics | Antineoplastic Combined Chemotherapy Protocols - blood | Cytochrome P-450 CYP3A | Humans | Microsomes, Liver - metabolism | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Tamoxifen - administration & dosage | Antineoplastic Agents, Hormonal - pharmacokinetics | Paroxetine - administration & dosage | Paroxetine - blood | Breast Neoplasms - enzymology | Adult | Female | Serotonin Uptake Inhibitors - blood | Chemotherapy, Adjuvant | Antineoplastic Agents, Hormonal - administration & dosage | Enzyme Inhibitors - pharmacology | Tamoxifen - blood | Selective Estrogen Receptor Modulators - administration & dosage | Treatment Outcome | Tamoxifen - pharmacokinetics | Breast Neoplasms - drug therapy | Antineoplastic Agents, Hormonal - blood | Selective Estrogen Receptor Modulators - blood | Serotonin Uptake Inhibitors - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - blood | Tamoxifen - analogs & derivatives | Aged | Paroxetine | Evaluation | Serotonin uptake inhibitors | Tamoxifen
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 05/2018, Volume 103, Issue 5, pp. 755 - 757
This issue of Clinical Pharmacology & Therapeutics (CPT) includes the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for using CYP2D6... 
BREAST-CANCER | PHARMACOLOGY & PHARMACY | BIOTRANSFORMATION | GENOTYPE | METABOLITE
Journal Article
Reference
Journal of the National Cancer Institute, ISSN 0027-8874, 01/2005, Volume 97, Issue 1, pp. 30 - 39
Background: The efficacy of tamoxifen therapy for the treatment of breast cancer varies widely among individuals. Plasma concentrations of the active tamoxifen... 
PERFORMANCE LIQUID-CHROMATOGRAPHY | TRIAL | IN-VITRO | PLASMA | ONCOLOGY | JAPANESE POPULATION | ALLELE FREQUENCY | PAROXETINE | POSTMENOPAUSAL WOMEN | HOT FLASHES | CYTOCHROME-P450 2D6 | Cytochrome P-450 CYP2C9 | Cytochrome P-450 CYP2D6 Inhibitors | Prospective Studies | Cytochrome P-450 CYP3A | Humans | Middle Aged | Aryl Hydrocarbon Hydroxylases - genetics | Antidepressive Agents, Second-Generation - administration & dosage | Tamoxifen - administration & dosage | Antineoplastic Agents, Hormonal - metabolism | Breast Neoplasms - metabolism | Breast Neoplasms - enzymology | Cyclohexanols - metabolism | Time Factors | Adult | Female | Chemotherapy, Adjuvant | Serotonin Uptake Inhibitors - metabolism | Tamoxifen - metabolism | Cytochrome P-450 CYP2D6 - genetics | Drug Administration Schedule | Enzyme Inhibitors - metabolism | Estrogen Receptor Modulators - administration & dosage | Antineoplastic Agents, Hormonal - administration & dosage | Tamoxifen - blood | Genotype | Arylsulfotransferase - genetics | Estrogen Receptor Modulators - blood | Breast Neoplasms - drug therapy | Antineoplastic Agents, Hormonal - blood | Venlafaxine Hydrochloride | Serotonin Uptake Inhibitors - administration & dosage | Cytochrome P-450 Enzyme System - genetics | Aged | Estrogen Receptor Modulators - metabolism | Antidepressive Agents, Second-Generation - metabolism | Breast cancer | Dosage and administration | Drug therapy | Tamoxifen | Antidepressants
Journal Article
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, ISSN 0277-0008, 08/2010, Volume 30, Issue 8, pp. 787 - 796
Journal Article