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science & technology (28) 28
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peptides (22) 22
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1. Full Text Prosit: proteome-wide prediction of peptide tandem mass spectra by deep learning
by Gessulat, Siegfried and Schmidt, Tobias and Zolg, Daniel Paul and Samaras, Patroklos and Schnatbaum, Karsten and Zerweck, Johannes and Knaute, Tobias and Rechenberger, Julia and Delanghe, Bernard and Huhmer, Andreas and Reimer, Ulf and Ehrlich, Hans-Christian and Aiche, Stephan and Kuster, Bernhard and Wilhelm, Mathias
Nature methods, ISSN 1548-7091, 06/2019, Volume 16, Issue 6, pp. 509 - 518
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | Post-translational modification | Usage | Peptides | Neural networks | Machine learning | Proteomics | Mass spectrometry | Identification and classification | Methods | Artificial neural networks | Mass spectroscopy | Database searching | Retention time | Tryptic peptides | Data bases | Spectrometry | Trypsin | Databases | Prediction models | Libraries | Mass spectra | Index Medicus
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2. Full Text An acetylome peptide microarray reveals specificities and deacetylation substrates for all human sirtuin isoforms
by Rauh, David and Fischer, Frank and Gertz, Melanie and Lakshminarasimhan, Mahadevan and Bergbrede, Tim and Aladini, Firouzeh and Kambach, Christian and Becker, Christian F. W and Zerweck, Johannes and Schutkowski, Mike and Steegborn, Clemens
Nature communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, pp. 2327 - 2327
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Amino Acid Sequence | Enzyme-Linked Immunosorbent Assay | Peptides - chemistry | Signal Transduction | Humans | Fluorescence | Models, Molecular | Molecular Sequence Data | Substrate Specificity | Proteome - chemistry | Peptides - metabolism | Protein Isoforms - metabolism | Sirtuins - chemistry | Protein Isoforms - chemistry | Protein Array Analysis | Acetylation | Binding Sites | Proteome - metabolism | Sirtuins - metabolism | Index Medicus
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3. Full Text Building ProteomeTools based on a complete synthetic human proteome
by Zolg, Daniel P and Wilhelm, Mathias and Schnatbaum, Karsten and Zerweck, Johannes and Knaute, Tobias and Delanghe, Bernard and Bailey, Derek J and Gessulat, Siegfried and Ehrlich, Hans-Christian and Weininger, Maximilian and Yu, Peng and Schlegl, Judith and Kramer, Karl and Schmidt, Tobias and Kusebauch, Ulrike and Deutsch, Eric W and Aebersold, Ruedi and Moritz, Robert L and Wenschuh, Holger and Moehring, Thomas and Aiche, Stephan and Huhmer, Andreas and Reimer, Ulf and Kuster, Bernhard
Nature methods, ISSN 1548-7091, 02/2017, Volume 14, Issue 3, pp. 259 - 262
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | Databases, Protein | Humans | Proteome - analysis | Proteomics - methods | Chromatography, Liquid - methods | Tandem Mass Spectrometry - methods | Genome, Human - genetics | Cellular proteins | Properties | Proteomics | Innovations | Computational biology | Index Medicus | peptide fragmentation | tandem mass spectrometry | proteomics | protein quantification | reference spectra | bioinformatics | spectral library | ProteomeTools | synthetic peptides | Liquid chromatography | protein identification | reference standards
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4. Full Text Molecular mechanism of synergy between the antimicrobial peptides PGLa and magainin 2
by Zerweck, Jonathan and Strandberg, Erik and Kukharenko, Olga and Reichert, Johannes and Bürck, Jochen and Wadhwani, Parvesh and Ulrich, Anne S
Scientific reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 1 - 21
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Antimicrobial activity | Nuclear magnetic resonance--NMR | Peptides | Antimicrobial peptides | Antimicrobial agents | Skin | C-Terminus | Hydrophobicity | Magainin 2 | Electrostatic properties | Index Medicus
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5. Full Text PROCAL: A Set of 40 Peptide Standards for Retention Time Indexing, Column Performance Monitoring, and Collision Energy Calibration
by Zolg, Daniel Paul and Wilhelm, Mathias and Yu, Peng and Knaute, Tobias and Zerweck, Johannes and Wenschuh, Holger and Reimer, Ulf and Schnatbaum, Karsten and Kuster, Bernhard
Proteomics (Weinheim), ISSN 1615-9853, 11/2017, Volume 17, Issue 21, pp. 1700263 - n/a
Synthetic peptides | LC–MS/MS | Retention time index | Retention time standardization | ProteomeTools | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | Peptide Fragments - analysis | Reference Standards | Tandem Mass Spectrometry - standards | Chromatography, Liquid - standards | Proteomics - standards | Humans | Proteins - analysis | Calibration | HeLa Cells | Proteomics - methods | Chromatography, Liquid - methods | Tandem Mass Spectrometry - methods | Usage | Peptides | Analysis | Chromatography | Laboratories | Data acquisition | Data processing | Hydrophobicity | Retention | Retention time | Standards | Data transfer (computers) | Mass spectrometers | Spectrometers | Proteomics | Monitoring | Index Medicus
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6. Full Text Quantification of the epitope diversity of HIV-1-specific binding antibodies by peptide microarrays for global HIV-1 vaccine development
by Stephenson, Kathryn E and Neubauer, George H and Reimer, Ulf and Pawlowski, Nikolaus and Knaute, Tobias and Zerweck, Johannes and Korber, Bette T and Barouch, Dan H and Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Journal of immunological methods, ISSN 0022-1759, 01/2015, Volume 416, Issue C, pp. 105 - 123
Vaccine | HIV | Antibody | Peptide microarray | Diversity | Biochemistry & Molecular Biology | Immunology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | Epitopes - immunology | HIV Infections - immunology | HIV-1 - immunology | Animals | Guinea Pigs | HIV Antibodies - immunology | Immunoglobulin G - immunology | Humans | Peptides - immunology | AIDS Vaccines - immunology | Macaca mulatta - immunology | Development and progression | Vaccines | Peptides | HIV (Viruses) | Antigenic determinants | Index Medicus | diversity | vaccine | antibody | peptide microarray | 60 APPLIED LIFE SCIENCES
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7. Full Text Homo- and heteromeric interaction strengths of the synergistic antimicrobial peptides PGLa and magainin 2 in membranes
by Zerweck, Jonathan and Strandberg, Erik and Bürck, Jochen and Reichert, Johannes and Wadhwani, Parvesh and Kukharenko, Olga and Ulrich, Anne S
European biophysics journal, ISSN 0175-7571, 9/2016, Volume 45, Issue 6, pp. 535 - 547
Biochemistry, general | Solid-state NMR | Membrane-active amphiphilic helices | Membrane Biology | Neurobiology | Biophysics and Biological Physics | Cell Biology | Life Sciences | Synergistic antimicrobial peptides | Vesicle leakage assay | Peptide dimerization | Hill coefficients | Nanotechnology | Life Sciences & Biomedicine | Biophysics | Science & Technology | Drug Synergism | Amino Acid Sequence | Thermodynamics | Antimicrobial Cationic Peptides - chemistry | Antimicrobial Cationic Peptides - pharmacology | Cell Membrane - metabolism | Magainins - pharmacology | Cell Membrane - drug effects | Magainins - chemistry | Peptides | Analysis | Antimicrobial agents | Index Medicus
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8. Full Text New Approaches for Absolute Quantification of Stable‐Isotope‐Labeled Peptide Standards for Targeted Proteomics Based on a UV Active Tag
by Schnatbaum, Karsten and Solis‐Mezarino, Victor and Pokrovsky, Daniil and Schäfer, Frederike and Nagl, Dennis and Hornberger, Lars and Zerweck, Johannes and Knaute, Tobias and Avramova‐Nehmer, Julia and Schutkowski, Mike and Hornung, Veit and Wenschuh, Holger and Völker‐Albert, Moritz Carl and Imhof, Axel and Reimer, Ulf
Proteomics (Weinheim), ISSN 1615-9853, 05/2020, Volume 20, Issue 10, pp. e2000007 - n/a
targeted proteomics | absolute quantification | reference peptides | histone quantification | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | Chemical precipitation | Peptides | Stable isotopes | Proteomics | Vials | Histone methyltransferase | Amino acids | Workflow | In vivo methods and tests | Quantitation | Standards | Index Medicus
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9. Full Text Proteometools: Systematic characterization of 21 post-translational protein modifications by liquid chromatography tandem mass spectrometry (lc-ms/ms) using synthetic peptides
by Paul Zolg, Daniel and Wilhelm, Mathias and Schmidt, Tobias and Médard, Guillaume and Zerweck, Johannes and Knaute, Tobias and Wenschuh, Holger and Reimer, Ulf and Schnatbaum, Karsten and Kuster, Bernhard
Molecular & cellular proteomics, ISSN 1535-9476, 09/2018, Volume 17, Issue 9, pp. 1850 - 1863
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | Index Medicus | Phosphorylation | Peptides | ProteomeTools | Technological Innovation and Resources | peptide fragmentation | Tandem Mass Spectrometry | Post-translational modifications | Peptide Synthesis | immonium ion | diagnostic ion | neutral loss | Acetylation | Methylation | Bioinformatics
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10. Full Text Data, Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing
by Zecha, Jana and Zecha, Jana and Lee, Chien-Yun and Lee, Chien-Yun and Bayer, Florian P and Meng, Chen and Meng, Chen and Grass, Vincent and Zerweck, Johannes and Schnatbaum, Karsten and Michler, Thomas and Michler, Thomas and Pichlmair, Andreas and Ludwig, Christina and Ludwig, Christina and Kuster, Bernhard and Kuster, Bernhard
Molecular & cellular proteomics, ISSN 1535-9476, 09/2020, Volume 19, Issue 9, pp. 1503 - 1522
COVID-19 | ACE2 | SARS-CoV-2 | parallel reaction monitoring | label-free quantification | clinical proteomics | mass spectrometry | targeted mass spectrometry | stable-isotope labeling | Vero E6 | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | Betacoronavirus - pathogenicity | Pandemics | Signal Recognition Particle - metabolism | Humans | Open Reading Frames | Signal Recognition Particle - genetics | Viral Proteins - metabolism | Case-Control Studies | Virus Internalization | Peptidyl-Dipeptidase A - genetics | Pneumonia, Viral - genetics | BRCA1 Protein - metabolism | Peptidyl-Dipeptidase A - metabolism | Serine Endopeptidases - genetics | Proteomics - methods | Vero Cells | Gene Ontology | Caco-2 Cells | A549 Cells | Amino Acid Sequence | Chlorocebus aethiops | Signal Transduction | Molecular Sequence Annotation | Pneumonia, Viral - pathology | Proteomics - instrumentation | Gene Expression Regulation | Coronavirus Infections - genetics | Viral Proteins - genetics | Viral Proteins - classification | Angiotensin-Converting Enzyme 2 | BRCA1 Protein - genetics | Animals | Coronavirus Infections - virology | Host-Pathogen Interactions - genetics | Coronavirus Infections - pathology | Indicators and Reagents | Serine Endopeptidases - metabolism | Betacoronavirus - genetics | Pneumonia, Viral - virology | Index Medicus | Research
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