Physical Review B - Condensed Matter and Materials Physics, ISSN 0163-1829, 04/1997, Volume 55, Issue 15, pp. 9391 - 9399
The attributes of electron field emission from disordered matrix arrays of carbon nanotubes are studied and found to be quite reproducible in spite of the...
PHYSICS, CONDENSED MATTER | K UK PHYSICS, CONDENSED MATTER | ELECTRON-EMISSION | MICROTUBULES | COMPOSITE
PHYSICS, CONDENSED MATTER | K UK PHYSICS, CONDENSED MATTER | ELECTRON-EMISSION | MICROTUBULES | COMPOSITE
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 03/2014, Volume 175, Issue 3, pp. 373 - 384
Summary Monoclonal antibodies (mAbs) are used as therapeutics in a number of disciplines in medicine, such as oncology, rheumatology, gastroenterology,...
alemtuzumab | multiple sclerosis | daclizumab | natalizumab | rituximab | Daclizumab | Rituximab | Multiple sclerosis | Alemtuzumab | Natalizumab | CONTROLLED PHASE-3 TRIAL | IMMUNOLOGY | DISEASE-ACTIVITY | MULTICENTER TRIAL | PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY | NEUROMYELITIS-OPTICA | AUTOIMMUNE-DISEASES | GLATIRAMER ACETATE | PLACEBO-CONTROLLED TRIAL | LYMPHOCYTE DEPLETION | INTERFERON BETA-1A | Antibodies, Monoclonal - administration & dosage | Humans | Antibodies, Monoclonal - adverse effects | Immunologic Factors - administration & dosage | Antibodies, Monoclonal - therapeutic use | Immunologic Factors - adverse effects | Immunologic Factors - therapeutic use | Multiple Sclerosis - drug therapy | Monoclonal antibodies | Biological products | Drug therapy | Medical research | Review
alemtuzumab | multiple sclerosis | daclizumab | natalizumab | rituximab | Daclizumab | Rituximab | Multiple sclerosis | Alemtuzumab | Natalizumab | CONTROLLED PHASE-3 TRIAL | IMMUNOLOGY | DISEASE-ACTIVITY | MULTICENTER TRIAL | PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY | NEUROMYELITIS-OPTICA | AUTOIMMUNE-DISEASES | GLATIRAMER ACETATE | PLACEBO-CONTROLLED TRIAL | LYMPHOCYTE DEPLETION | INTERFERON BETA-1A | Antibodies, Monoclonal - administration & dosage | Humans | Antibodies, Monoclonal - adverse effects | Immunologic Factors - administration & dosage | Antibodies, Monoclonal - therapeutic use | Immunologic Factors - adverse effects | Immunologic Factors - therapeutic use | Multiple Sclerosis - drug therapy | Monoclonal antibodies | Biological products | Drug therapy | Medical research | Review
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 04/2019, Volume 202, Issue 8, pp. 2177 - 2187
Inflammasomes are protein complexes that respond to a wide range of pathogens and cellular damage signals. Their activation prompts the caspase-1-mediated...
SYSTEMIC-LUPUS-ERYTHEMATOSUS | MULTIPLE-SCLEROSIS | GENETIC ASSOCIATION | PERIPHERAL-BLOOD | NLRP3 INFLAMMASOME | IMMUNOLOGY | NOD-LIKE RECEPTOR | BLOOD MONONUCLEAR-CELLS | DECREASED EXPRESSION | PARKINSONS-DISEASE | MIR-146A EXPRESSION
SYSTEMIC-LUPUS-ERYTHEMATOSUS | MULTIPLE-SCLEROSIS | GENETIC ASSOCIATION | PERIPHERAL-BLOOD | NLRP3 INFLAMMASOME | IMMUNOLOGY | NOD-LIKE RECEPTOR | BLOOD MONONUCLEAR-CELLS | DECREASED EXPRESSION | PARKINSONS-DISEASE | MIR-146A EXPRESSION
Journal Article
Autoimmunity Reviews, ISSN 1568-9972, 09/2017, Volume 16, Issue 9, pp. 925 - 936
In contrast to other diseases that go along with spasticity (e.g. spinal cord injury), spasticity in chronic autoimmune diseases involving the CNS is...
Spasticity | Neuroinflammation | Multiple sclerosis | Cytokines | Neurodegeneration | SYNAPTIC-TRANSMISSION | NECROSIS-FACTOR-ALPHA | IMMUNOLOGY | MECHANICAL-PROPERTIES | ENHANCED SPASTICITY | PARAVENTRICULAR NUCLEUS | MITOCHONDRIAL CHANGES | INTRATHECAL TRIAMCINOLONE-ACETONIDE | INTERFERON-BETA THERAPY | GLATIRAMER ACETATE | MS PATIENTS | Autoimmunity | Neurons | Health aspects | Immunotherapy
Spasticity | Neuroinflammation | Multiple sclerosis | Cytokines | Neurodegeneration | SYNAPTIC-TRANSMISSION | NECROSIS-FACTOR-ALPHA | IMMUNOLOGY | MECHANICAL-PROPERTIES | ENHANCED SPASTICITY | PARAVENTRICULAR NUCLEUS | MITOCHONDRIAL CHANGES | INTRATHECAL TRIAMCINOLONE-ACETONIDE | INTERFERON-BETA THERAPY | GLATIRAMER ACETATE | MS PATIENTS | Autoimmunity | Neurons | Health aspects | Immunotherapy
Journal Article
Autoimmunity Reviews, ISSN 1568-9972, 2015, Volume 14, Issue 10, pp. 903 - 913
Abstract Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system, usually occurring in young adults and leading to...
Allergy and Immunology | Multiple sclerosis | Molecular biomarker | Prognosis | Cerebrospinal fluid | Diagnosis | Monitoring | OLIGOCLONAL BANDS | CLINICALLY ISOLATED SYNDROME | AXONAL DAMAGE | NECROSIS-FACTOR-ALPHA | IMMUNOLOGY | SOLUBLE ADHESION MOLECULES | MYELIN OLIGODENDROCYTE GLYCOPROTEIN | INTRATHECAL IGM-SYNTHESIS | NEUROFILAMENT LIGHT | PROGNOSTIC MARKER | ANTIBODY-RESPONSE | Development and progression | Biological markers | Aquaporins
Allergy and Immunology | Multiple sclerosis | Molecular biomarker | Prognosis | Cerebrospinal fluid | Diagnosis | Monitoring | OLIGOCLONAL BANDS | CLINICALLY ISOLATED SYNDROME | AXONAL DAMAGE | NECROSIS-FACTOR-ALPHA | IMMUNOLOGY | SOLUBLE ADHESION MOLECULES | MYELIN OLIGODENDROCYTE GLYCOPROTEIN | INTRATHECAL IGM-SYNTHESIS | NEUROFILAMENT LIGHT | PROGNOSTIC MARKER | ANTIBODY-RESPONSE | Development and progression | Biological markers | Aquaporins
Journal Article
Progress in Neurobiology, ISSN 0301-0082, 2010, Volume 92, Issue 3, pp. 386 - 404
▶ The classical MOG -EAE is complemented by novel cortical and toxic MS models. ▶ Putative autoantigens of EAE/MS include myelin and axonal glycoproteins and...
Autoimmunity | Experimental autoimmune encephalomyelitis | Animal model | Immunogenetics | Multiple sclerosis | Immunomodulatory therapy | GLATIRAMER ACETATE TREATMENT | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | NEUROSCIENCES | MYELIN OLIGODENDROCYTE GLYCOPROTEIN | PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY | REGULATORY T-CELLS | BRAIN-BARRIER DISRUPTION | PHOSPHODIESTERASE INHIBITOR PENTOXIFYLLINE | CENTRAL-NERVOUS-SYSTEM | DISEASE-MODIFYING THERAPIES | Encephalomyelitis, Autoimmune, Experimental - physiopathology | History, 21st Century | Animals, Genetically Modified | History, 20th Century | Humans | Encephalomyelitis, Autoimmune, Experimental - immunology | Multiple Sclerosis - genetics | Clinical Trials as Topic | Gene Expression Profiling | Multiple Sclerosis - therapy | Encephalomyelitis, Autoimmune, Experimental - therapy | Multiple Sclerosis - physiopathology | Animals | Microarray Analysis | Multiple Sclerosis - immunology | History, 19th Century | Encephalomyelitis, Autoimmune, Experimental - genetics | Disease Models, Animal
Autoimmunity | Experimental autoimmune encephalomyelitis | Animal model | Immunogenetics | Multiple sclerosis | Immunomodulatory therapy | GLATIRAMER ACETATE TREATMENT | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | NEUROSCIENCES | MYELIN OLIGODENDROCYTE GLYCOPROTEIN | PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY | REGULATORY T-CELLS | BRAIN-BARRIER DISRUPTION | PHOSPHODIESTERASE INHIBITOR PENTOXIFYLLINE | CENTRAL-NERVOUS-SYSTEM | DISEASE-MODIFYING THERAPIES | Encephalomyelitis, Autoimmune, Experimental - physiopathology | History, 21st Century | Animals, Genetically Modified | History, 20th Century | Humans | Encephalomyelitis, Autoimmune, Experimental - immunology | Multiple Sclerosis - genetics | Clinical Trials as Topic | Gene Expression Profiling | Multiple Sclerosis - therapy | Encephalomyelitis, Autoimmune, Experimental - therapy | Multiple Sclerosis - physiopathology | Animals | Microarray Analysis | Multiple Sclerosis - immunology | History, 19th Century | Encephalomyelitis, Autoimmune, Experimental - genetics | Disease Models, Animal
Journal Article
European Neurology, ISSN 0014-3022, 05/2014, Volume 71, Issue 5-6, pp. 271 - 279
Background: Nabiximols (Sativex®), a cannabinoid-based oromucosal spray, is an add-on therapy for patients with moderate to severe multiple sclerosis...
Original Paper | Spasticity | Cannabinoids | Multiple sclerosis | Tolerability | Effectiveness | Nabiximols | CONTROLLED-TRIAL | RELIABILITY | ASHWORTH SCALE | NEUROSCIENCES | CLINICAL NEUROLOGY | EDSS | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Male | Neuromuscular Agents - therapeutic use | Muscle Spasticity - drug therapy | Young Adult | Multiple Sclerosis - physiopathology | Cannabidiol - adverse effects | Adult | Female | Surveys and Questionnaires | Cannabidiol - therapeutic use | Severity of Illness Index | Dronabinol - adverse effects | Treatment Outcome | Sleep - drug effects | Neuromuscular Agents - adverse effects | Aged | Muscle Spasticity - physiopathology | Plant Extracts - therapeutic use | Dronabinol - therapeutic use | Drug Combinations | Germany | Multiple Sclerosis - drug therapy | Plant Extracts - adverse effects
Original Paper | Spasticity | Cannabinoids | Multiple sclerosis | Tolerability | Effectiveness | Nabiximols | CONTROLLED-TRIAL | RELIABILITY | ASHWORTH SCALE | NEUROSCIENCES | CLINICAL NEUROLOGY | EDSS | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Male | Neuromuscular Agents - therapeutic use | Muscle Spasticity - drug therapy | Young Adult | Multiple Sclerosis - physiopathology | Cannabidiol - adverse effects | Adult | Female | Surveys and Questionnaires | Cannabidiol - therapeutic use | Severity of Illness Index | Dronabinol - adverse effects | Treatment Outcome | Sleep - drug effects | Neuromuscular Agents - adverse effects | Aged | Muscle Spasticity - physiopathology | Plant Extracts - therapeutic use | Dronabinol - therapeutic use | Drug Combinations | Germany | Multiple Sclerosis - drug therapy | Plant Extracts - adverse effects
Journal Article
Acta Neurologica Scandinavica, ISSN 0001-6314, 03/2014, Volume 129, Issue 3, pp. 154 - 162
Aims To gain real‐life data on demographic and clinical characteristics, treatment patterns, treatment satisfaction and quality‐of‐life of multiple...
spasticity | quality‐of‐life | treatment satisfaction | multiple sclerosis | drug treatment | Spasticity | Multiple sclerosis | Quality-of-life | Treatment satisfaction | Drug treatment | DISABILITY | RELIABILITY | quality-of-life | SCALE | CLINICAL NEUROLOGY | Disability Evaluation | Multiple Sclerosis - psychology | Cross-Sectional Studies | Humans | Middle Aged | Male | Multiple Sclerosis - therapy | Activities of Daily Living | Multiple Sclerosis - complications | Muscle Spasticity - etiology | Quality of Life | Adult | Female | Surveys and Questionnaires | Retrospective Studies | Germany | Muscle Relaxants, Central - therapeutic use | Care and treatment | Age
spasticity | quality‐of‐life | treatment satisfaction | multiple sclerosis | drug treatment | Spasticity | Multiple sclerosis | Quality-of-life | Treatment satisfaction | Drug treatment | DISABILITY | RELIABILITY | quality-of-life | SCALE | CLINICAL NEUROLOGY | Disability Evaluation | Multiple Sclerosis - psychology | Cross-Sectional Studies | Humans | Middle Aged | Male | Multiple Sclerosis - therapy | Activities of Daily Living | Multiple Sclerosis - complications | Muscle Spasticity - etiology | Quality of Life | Adult | Female | Surveys and Questionnaires | Retrospective Studies | Germany | Muscle Relaxants, Central - therapeutic use | Care and treatment | Age
Journal Article
Expert Opinion on Pharmacotherapy, ISSN 1465-6566, 03/2018, Volume 19, Issue 5, pp. 483 - 498
Introduction: Multiple sclerosis (MS) is an immune-mediated and neurodegenerative disease with an unpredictable outcome. Immune-modulatory treatment aims at...
interferon beta | Multiple sclerosis | ocrelizumab | dimethylfumarate | alemtuzumab | cladribine | fingolimod | teriflunomide | glatiramer acetate | natalizumab | daclizumab | HIGH-YIELD PROCESS | CONTROLLED PHASE-3 | GRANULE CELL NEURONOPATHY | FUMARIC-ACID ESTERS | PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY | VARICELLA-ZOSTER-VIRUS | INTERFERON-BETA THERAPY | TERM-FOLLOW-UP | PHARMACOLOGY & PHARMACY | PLACEBO-CONTROLLED TRIAL | DISEASE-MODIFYING THERAPIES | Alemtuzumab - adverse effects | Neoplasms - etiology | Crotonates - metabolism | Alemtuzumab - metabolism | Humans | Immunosuppressive Agents - therapeutic use | Natalizumab - adverse effects | Natalizumab - metabolism | Interferon-beta - therapeutic use | Interferon-beta - adverse effects | Natalizumab - therapeutic use | Fingolimod Hydrochloride - adverse effects | Fingolimod Hydrochloride - therapeutic use | Toluidines - therapeutic use | Toluidines - metabolism | Toluidines - adverse effects | Fingolimod Hydrochloride - metabolism | Crotonates - therapeutic use | Glatiramer Acetate - adverse effects | Cladribine - metabolism | Interferon-beta - metabolism | Cladribine - therapeutic use | Glatiramer Acetate - therapeutic use | Multiple Sclerosis - pathology | Glatiramer Acetate - metabolism | Immunosuppressive Agents - adverse effects | Immunologic Factors - adverse effects | Cladribine - adverse effects | Crotonates - adverse effects | Alemtuzumab - therapeutic use | Immunologic Factors - therapeutic use | Multiple Sclerosis - drug therapy
interferon beta | Multiple sclerosis | ocrelizumab | dimethylfumarate | alemtuzumab | cladribine | fingolimod | teriflunomide | glatiramer acetate | natalizumab | daclizumab | HIGH-YIELD PROCESS | CONTROLLED PHASE-3 | GRANULE CELL NEURONOPATHY | FUMARIC-ACID ESTERS | PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY | VARICELLA-ZOSTER-VIRUS | INTERFERON-BETA THERAPY | TERM-FOLLOW-UP | PHARMACOLOGY & PHARMACY | PLACEBO-CONTROLLED TRIAL | DISEASE-MODIFYING THERAPIES | Alemtuzumab - adverse effects | Neoplasms - etiology | Crotonates - metabolism | Alemtuzumab - metabolism | Humans | Immunosuppressive Agents - therapeutic use | Natalizumab - adverse effects | Natalizumab - metabolism | Interferon-beta - therapeutic use | Interferon-beta - adverse effects | Natalizumab - therapeutic use | Fingolimod Hydrochloride - adverse effects | Fingolimod Hydrochloride - therapeutic use | Toluidines - therapeutic use | Toluidines - metabolism | Toluidines - adverse effects | Fingolimod Hydrochloride - metabolism | Crotonates - therapeutic use | Glatiramer Acetate - adverse effects | Cladribine - metabolism | Interferon-beta - metabolism | Cladribine - therapeutic use | Glatiramer Acetate - therapeutic use | Multiple Sclerosis - pathology | Glatiramer Acetate - metabolism | Immunosuppressive Agents - adverse effects | Immunologic Factors - adverse effects | Cladribine - adverse effects | Crotonates - adverse effects | Alemtuzumab - therapeutic use | Immunologic Factors - therapeutic use | Multiple Sclerosis - drug therapy
Journal Article
Journal of Neurology, ISSN 0340-5354, 05/2017, Volume 264, Issue 5, pp. 1032 - 1034
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1007/s00415-016-8315-9
CLINICAL NEUROLOGY | Neurology - history | History, 19th Century | Neurophysiology - history | History, 20th Century | Humans | Germany
CLINICAL NEUROLOGY | Neurology - history | History, 19th Century | Neurophysiology - history | History, 20th Century | Humans | Germany
Journal Article