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1. Editorial: biomarkers of osteoarthritis (guest editor: guangju zhai)
by Zhai, Guangju
Current rheumatology reviews, ISSN 1573-3971, 2010, Volume 6, Issue 4, p. 233
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2. Full Text Common genetic determinants of vitamin D insufficiency: a genome-wide association study
by Wang, Thomas J, MD and Zhang, Feng, PhD and Richards, J Brent, MD and Kestenbaum, Bryan, MD and van Meurs, Joyce B, PhD and Berry, Diane, MSc and Kiel, Douglas P, MD and Streeten, Elizabeth A, MD and Ohlsson, Claes, Prof and Koller, Daniel L, PhD and Peltonen, Leena, Prof and Cooper, Jason D, PhD and O'Reilly, Paul F, PhD and Houston, Denise K, PhD and Glazer, Nicole L, PhD and Vandenput, Liesbeth, PhD and Peacock, Munro, Prof and Shi, Julia, MSc and Rivadeneira, Fernando, PhD and McCarthy, Mark I, Prof and Anneli, Pouta, PhD and de Boer, Ian H, MD and Mangino, Massimo, PhD and Kato, Bernet, PhD and Smyth, Deborah J, BSc and Booth, Sarah L, Prof and Jacques, Paul F, ScD and Burke, Greg L, Prof and Goodarzi, Mark, Prof and Cheung, Ching-Lung, PhD and Wolf, Myles, MD and Rice, Kenneth, PhD and Goltzman, David, Prof and Hidiroglou, Nick, PhD and Ladouceur, Martin, PhD and Wareham, Nicholas J, Prof and Hocking, Lynne J, PhD and Hart, Deborah, PhD and Arden, Nigel K, Prof and Cooper, Cyrus, Prof and Malik, Suneil, PhD and Fraser, William D, Prof and Hartikainen, Anna-Liisa, Prof and Zhai, Guangju, PhD and Macdonald, Helen M, PhD and Forouhi, Nita G, FFPH and Loos, Ruth JF, PhD and Reid, David M, Prof and Hakim, Alan, MA and Dennison, Elaine, PhD and Liu, Yongmei, PhD and Power, Chris, Prof and Stevens, Helen E, HNC and Jaana, Laitinen, PhD and Vasan, Ramachandran S, Prof and Soranzo, Nicole, PhD and Bojunga, Jörg, MD and Psaty, Bruce M, Prof and Lorentzon, Mattias, PhD and Foroud, Tatiana, Prof and Harris, Tamara B, MD and Hofman, Albert, Prof and Jansson, John-Olov, Prof and Cauley, Jane A, PhD and Uitterlinden, Andre G, Prof and Gibson, Quince, MBA and Järvelin, Marjo-Riitta, Prof and Karasik, David, PhD and Siscovick, David S, Prof and Econs, Michael J, Prof and Kritchevsky, Stephen B, Prof and Florez, Jose C, PhD and Todd, John A, Prof and Dupuis, Josee, Prof and Hyppönen, Elina, PhD and Spector, Timothy D, Prof and Göteborgs universitet and Gothenburg University and Institutionen för medicin, avdelningen för invärtesmedicin and Institute of Neuroscience and Physiology, Department of Physiology and Sahlgrenska Academy and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi and Institute of Medicine, Department of Internal Medicine
The Lancet, ISSN 0140-6736, 2010, Volume 376, Issue 9736, pp. 180 - 188
Summary Background Vitamin D is crucial for maintenance of musculoskeletal health, and might also have a role in extraskeletal tissues. Determinants of... 
Internal Medicine | RANDOMIZED CONTROLLED-TRIALS | MEDICINE, GENERAL & INTERNAL | CANCER RISK | METAANALYSIS | PLASMA-CONCENTRATIONS | LEMLI-OPITZ-SYNDROME | D SUPPLEMENTATION | CALCIUM | D DEFICIENCY | SERUM 25-HYDROXYVITAMIN-D | D-BINDING PROTEIN | Immunoassay | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Vitamin D Deficiency - genetics | United States | Europe | Humans | International Cooperation | Chromosomes, Human, Pair 4 | Linkage Disequilibrium | Vitamin D - blood | Canada | Homozygote | Vitamin D Deficiency - prevention & control | Vitamin D - genetics | Vitamin D Deficiency - blood | Heterozygote | Vitamin D - analogs & derivatives | Chromosomes, Human, Pair 11 | Polymorphism, Single Nucleotide | Seasons | Dietary Supplements | Cohort Studies | Vitamin D deficiency | Genetic aspects | Research | Genetic variation | Risk factors | Studies | Medical research | Vitamin D | Nutrition | Index Medicus | Abridged Index Medicus | Endokrinologi och diabetes | Endocrinology and Diabetes
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3. Full Text Human serum metabolic profiles are age dependent
by Yu, Zhonghao and Zhai, Guangju and Singmann, Paula and He, Ying and Xu, Tao and Prehn, Cornelia and Römisch‐Margl, Werner and Lattka, Eva and Gieger, Christian and Soranzo, Nicole and Heinrich, Joachim and Standl, Marie and Thiering, Elisabeth and Mittelstraß, Kirstin and Wichmann, Heinz‐Erich and Peters, Annette and Suhre, Karsten and Li, Yixue and Adamski, Jerzy and Spector, Tim D and Illig, Thomas and Wang‐Sattler, Rui
Aging Cell, ISSN 1474-9718, 12/2012, Volume 11, Issue 6, pp. 960 - 967
Understanding the complexity of aging is of utmost importance. This can now be addressed by the novel and powerful approach of metabolomics. However, to date,... 
epidemiology | aging | metabolomics | age | population‐based study | Aging | Population-based study | Metabolomics | Epidemiology | Age | SURVIVAL | OXIDATIVE STRESS | population-based study | CARNOSINE | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | KORA | LONGEVITY | DISEASE | PROTEINS | Body Mass Index | Multivariate Analysis | Age Factors | Oxidation-Reduction | Flow Injection Analysis | Humans | Metabolome - physiology | Middle Aged | Male | Biomarkers - blood | Aging - blood | Tandem Mass Spectrometry | Sex Factors | Aged, 80 and over | Adult | Female | Aged | Fatty Acids - metabolism | Usage | Environmental health | Genomes | Phospholipids | College teachers | Fatty acids | Biometry | Anopheles | Histidine | Metabolites | Analysis | Public health | Medical informatics | Index Medicus | Original
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4. Full Text Human metabolic individuality in biomedical and pharmaceutical research
by Suhre, Karsten and Shin, So-Youn and Petersen, Ann-Kristin and Mohney, Robert P and Meredith, David and Wägele, Brigitte and Altmaier, Elisabeth and Deloukas, Panos and Erdmann, Jeanette and Grundberg, Elin and Hammond, Christopher J and De Angelis, Martin Hrabé and Kastenmüller, Gabi and Köttgen, Anna and Kronenberg, Florian and Mangino, Massimo and Meisinger, Christa and Meitinger, Thomas and Mewes, Hans-Werner and Milburn, Michael V and Prehn, Cornelia and Raffler, Johannes and Ried, Janina S and Römisch-Margl, Werner and Samani, Nilesh J and Small, Kerrin S and -Erich Wichmann, H and Zhai, Guangju and Illig, Thomas and Spector, Tim D and Adamski, Jerzy and Soranzo, Nicole and Gieger, Christian and CARDIoGRAM
Nature, ISSN 0028-0836, 09/2011, Volume 477, Issue 7362, pp. 54 - 62
Genome-wide association studies (GWAS) have identified many risk loci for complex diseases, but effect sizes are typically small and information on the... 
GENETIC-VARIATION | CONTRIBUTE | METAANALYSIS | VARIANTS | MULTIDISCIPLINARY SCIENCES | TRANSPORTER FAMILY | RISK | LOCI | CHRONIC KIDNEY-DISEASE | BILIRUBIN LEVELS | GENOME-WIDE ASSOCIATION | Metabolomics | Diabetes Mellitus - genetics | Humans | Middle Aged | Genetic Loci - genetics | Male | Blood - metabolism | Genetic Variation | Young Adult | Aged, 80 and over | Adult | Biomedical Research | Female | Child | Metabolism - genetics | Renal Insufficiency - genetics | Genome-Wide Association Study | Pharmacogenetics | Drug Industry | Risk Factors | Genotype | Venous Thromboembolism - genetics | Adolescent | Coronary Artery Disease - genetics | Aged | Chronic Disease | Care and treatment | Usage | Physiological aspects | Crohn's disease | Genetic aspects | Genomes | Diagnosis | Research | Risk factors | Studies | Statistical analysis | Metabolites | Data collection | Genetics | Gene loci | Diabetes | Metabolism | Chronic illnesses | Index Medicus
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5. Full Text Food Addiction: Its Prevalence and Significant Association with Obesity in the General Population
by Pedram, Pardis and Wadden, Danny and Amini, Peyvand and Gulliver, Wayne and Randell, Edward and Cahill, Farrell and Vasdev, Sudesh and Goodridge, Alan and Carter, Jacqueline C and Zhai, Guangju and Ji, Yunqi and Sun, Guang
PLoS ONE, ISSN 1932-6203, 09/2013, Volume 8, Issue 9, pp. e74832 - e74832
Background: 'Food addiction' shares a similar neurobiological and behavioral framework with substance addiction. However whether, and to what degree, 'food... 
UNITED-STATES | CRAVINGS | MULTIDISCIPLINARY SCIENCES | VALIDATION | FAT | BRAIN | SUGAR | Behavior, Addictive - complications | Prevalence | Obesity - complications | Humans | Male | Newfoundland and Labrador - epidemiology | Behavior, Addictive - epidemiology | Diet | Obesity - epidemiology | Adult | Female | Obesity - etiology | Food | Obesity | Body mass index | Substance abuse | Food habits | Dual energy X-ray absorptiometry | Body fat | Energy measurement | Population studies | Males | Addictions | Community colleges | Body composition | Calories | Bulimia | Addiction | Body mass | Body composition (biology) | Correlation analysis | Addicts | Body size | Adults | Females | Index Medicus
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6. Full Text Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population
by Bell, Jordana T and Tsai, Pei-Chien and Yang, Tsun-Po and Pidsley, Ruth and Nisbet, James and Glass, Daniel and Mangino, Massimo and Zhai, Guangju and Zhang, Feng and Valdes, Ana and Shin, So-Youn and Dempster, Emma L and Murray, Robin M and Grundberg, Elin and Hedman, Asa K and Nica, Alexandra and Small, Kerrin S and Dermitzakis, Emmanouil T and McCarthy, Mark I and Mill, Jonathan and Spector, Tim D and Deloukas, Panos and MuTHER Consortium and The MuTHER Consortium
PLoS Genetics, ISSN 1553-7390, 04/2012, Volume 8, Issue 4, pp. 189 - 200
Age-related changes in DNA methylation have been implicated in cellular senescence and longevity, yet the causes and functional consequences of these variants... 
LEAN BODY-MASS | HUMAN BRAIN | BONE-MINERAL DENSITY | DNA METHYLATION | GENETICS & HEREDITY | GENE-EXPRESSION | ASSOCIATION | GALANIN RECEPTORS | GENOME | MONOZYGOTIC TWINS | TELOMERE LENGTH | Cellular Senescence - genetics | Genome-Wide Association Study | Genetic Association Studies | Twins, Monozygotic - genetics | Humans | Middle Aged | DNA Methylation - genetics | Longevity - genetics | Gene-Environment Interaction | Aging - genetics | Epigenesis, Genetic - genetics | Aged, 80 and over | CpG Islands - genetics | Adult | Female | Aged | Genome, Human | Quantitative Trait Loci - genetics | Phenotype | Research | Methylation | Population genetics | Genomics | Aging | DNA methylation | Genetics | Bone density | Deoxyribonucleic acid--DNA | Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap | Deoxyribonucleic acid | DNA
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7. Full Text A genome-wide perspective of genetic variation in human metabolism
by Römisch-Margl, Werner and Kronenberg, Florian and Wichmann, H-Erich and Prehn, Cornelia and Soranzo, Nicole and Adamski, Jerzy and Gieger, Christian and Altmaier, Elisabeth and Kastenmüller, Gabi and Illig, Thomas and Mewes, Hans-Werner and Wang-Sattler, Rui and Suhre, Karsten and de Angelis, Martin Hrabé and Kato, Bernet S and Spector, Tim D and Zhai, Guangju and Meitinger, Thomas
Nature Genetics, ISSN 1061-4036, 02/2010, Volume 42, Issue 2, pp. 137 - 141
Serum metabolite concentrations provide a direct readout of biological processes in the human body, and they are associated with disorders such as... 
FASTING GLUCOSE | POPULATION | METABOLOMICS | VARIANTS | DISEASE | FREQUENCY | GENETICS & HEREDITY | RISK | LOCI | POLYMORPHISM | ASSOCIATION | Genetic Variation | Genome-Wide Association Study | Reproducibility of Results | Humans | Genetic Loci - genetics | Polymorphism, Single Nucleotide - genetics | United Kingdom | Genome, Human - genetics | Metabolome - genetics | Metabolic diseases | Genetic aspects | Research | Genetic polymorphisms | Risk factors | Medical research | Ratios | Biomedical research | Sample size | Genetics | Grants | Metabolism | Mass spectrometry | Independent sample | Index Medicus
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8. Full Text Dynamics of Runoff and Suspended Sediment Transport in a Highly Erodible Catchment on the Chinese Loess Plateau
by Tian, Peng and Zhai, Jianqing and Zhao, Guangju and Mu, Xingmin
Land Degradation & Development, ISSN 1085-3278, 04/2016, Volume 27, Issue 3, pp. 839 - 850
Runoff is the key factor to understand the land degradation causing high risk of soil erosion and can reduce the water available for human societies and... 
soil and water conservation measures | runoff | suspended sediment | flow–sediment relationship | temporal variation | Suspended sediment | Temporal variation | Soil and water conservation measures | Runoff | Flow-sediment relationship | YELLOW-RIVER | flow-sediment relationship | ENVIRONMENTAL SCIENCES | SOIL SCIENCE | RIVER-BASIN | IMPACT | CONSERVATION | MESOSCALE CATCHMENT | STREAMFLOW | SOIL-EROSION | CLIMATE VARIABILITY | WORLDS RIVERS | WATER | Loess | Soil erosion | Sediment, Suspended | Analysis | Sediment transport | Degradation | Catchments | Dynamics | Water conservation | Floods | Sediments | Land
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9. Full Text New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
by Dupuis, Josée and Langenberg, Claudia and Prokopenko, Inga and Saxena, Richa and Soranzo, Nicole and Jackson, Anne and Wheeler, Eleanor and Glazer, Nicole and Bouatia-Naji, Nabila and Gloyn, Anna and Lindgren, Cecilia and Mägi, Reedik and Morris, Anew and Randall, Joshua and Johnson, Toby and Elliott, Paul and Rybin, Denis and Thorleifsson, Gudmar and Steinthorsdottir, Valgerdur and Henneman, Peter and Grallert, Harald and Dehghan, Abbas and JanHottenga, Jouke and Franklin, Christopher and Navarro, Pau and Song, Kijoung and Goel, Anuj and Perry, John and Egan, Josephine and Lajunen, Taina and Grarup, Niels and Sparsø, Thomas and Doney, Alex and Voight, Benjamin and Stringham, Heather and Li, Man and Kanoni, Stavroula and Shrader, Peter and Cavalcanti-Proença, Christine and Kumari, Meena and Qi, Lu and Timpson, Nicholas and Gieger, Christian and Zabena, Carina and Rocheleau, Ghislain and Ingelsson, Erik and An, Ping and O´Connell, J.R and Luan, J and McCarroll, Steven and Payne, Felicity and Roccasecca, R.M and Pattou, François and Sethupathy, Praveen and Ardlie, Kristin and Ariyurek, Yavuz and Balkau, Beverley and Barter, Phil and Beilby, John and Ben-Shlomo, Y and Benediktsson, Rafn and Bennett, Amanda and Bergmann, Sven and Bochud, Murielle and Boerwinkle, Eric and Bonnefond, Amélie and Bonnycastle, Lori and Borch-Johnsen, K and Böttcher, Yvonne and Brunner, Eric and Bumpstead, Suzannah and Charpentier, Guillaume and IdaChen, Yii and Chines, Peter and Clarke, R and McOin, Lachlan and Cooper, Matthew and Cornelis, Marilyn and Crawford, Gabe and Crisponi, Laura and Day, Ian and Geus, Eco and Delplanque, Jerome and Dina, Christian and Erdos, Michael and Fedson, Annette and Fischer-Rosinsky, Antje and Forouhi, Nita and Fox, Caroline and Frants, Rune and GraziaFranzosi, Maria and Galan, Pilar and Goodarzi, Mark and Graessler, Jürgen and Groves, Christopher and Grundy, Scott and Gwilliam, Rhian and Gyllensten, Ulf and Hadjadj, Samy and Hallmans, Göran and ... and DIAGRAM Consortium and Global BPgen Consortium and Anders Hamsten Procardis Consortiu and GIANT Consortium and MAGIC Investigators and Anders Hamsten on behalf of Procardis Consortium and MAGIC investigators and the MAGIC investigators and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Allmänmedicin and Näringsforskning and Umeå universitet and Medicin
Nature Genetics, ISSN 1061-4036, 02/2010, Volume 42, Issue 2, pp. 105 - 116
textabstractLevels of circulating glucose are tightly regulated. To identify new loci influencing glycemic traits, we performed meta-analyses of 21 genome-wide... 
CIRCADIAN CLOCK | DISEASE RISK | TRIGLYCERIDE LEVELS | INSULIN-RESISTANCE | GENETICS & HEREDITY | BETA-CELL DYSFUNCTION | PLASMA-GLUCOSE | MODEL ASSESSMENT | FOLLOW-UP | GENOME-WIDE ASSOCIATION | ESSENTIAL COMPONENTS | Genetic Predisposition to Disease | Genome-Wide Association Study | Meta-Analysis as Topic | Reproducibility of Results | Quantitative Trait, Heritable | Diabetes Mellitus, Type 2 - genetics | Humans | Gene Expression Regulation | Genetic Loci - genetics | Databases, Genetic | DNA Copy Number Variations - genetics | Fasting - blood | Adolescent | Alleles | Polymorphism, Single Nucleotide - genetics | Adult | Blood Glucose - genetics | Blood Glucose - metabolism | Child | Homeostasis - genetics | Quantitative Trait Loci - genetics | Type 2 diabetes | Homeostasis | Physiological aspects | Genetic aspects | Research | Insulin | Health aspects | Risk factors | Studies | Hyperglycemia | Diabetes | Sample size | Meta-analysis | Index Medicus | Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
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