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The Lancet, ISSN 0140-6736, 09/2019, Volume 394, Issue 10204, pp. 1125 - 1127
China's 2009 national health reform focused on health insurance, drugs, public health, hospitals, and primary care.1 On its tenth anniversary, evaluations of... 
Medical personnel | Health care | Health facilities | Nurse practitioners | Rural areas | Shortages | Health care policy | Medical services | Careers | Security | Primary care | Core curriculum | Demographics | Scholarships & fellowships | Hospitals | Education | Nurses | Insurance | Population | Public health
Journal Article
Digestive Diseases and Sciences, ISSN 0163-2116, 09/2019
Journal Article
Journal Article
by Huang, LJ and Wang, Y and Chen, J and Zhao, YB and Wang, YL and Ma, YP and Chen, X and Liu, WZ and Li, ZZ and Zhao, LM and Shan, BE and Dong, X and Li, D and Shao, SJ and Song, YM and Zhan, QM and Liu, XF
CELL DEATH & DISEASE, ISSN 2041-4889, 07/2019, Volume 10, Issue 7, pp. 513 - 14
Long noncoding RNAs (lncRNAs) play important roles in the development and progression of human cancers. The lncRNA prostate cancer-associated transcript 1... 
DIAGNOSIS | INVASION | METASTASIS | EMERGING ROLE | PROLIFERATION | GENOMIC CHARACTERIZATION | CANCER | PROMOTES | TUMORIGENESIS | EXPRESSION | CELL BIOLOGY | Cell proliferation | Cdc2 protein | Squamous cell carcinoma | Transcription | Invasiveness | Ribonucleic acid--RNA | Exosomes | Cyclin B1 | Esophagus | Cell growth | Cell lines | Paclitaxel | Cell cycle | Biomarkers | Prostate cancer | Tumors
Journal Article
by Fan, HJ and Yu, XY and Zou, ZG and Zheng, W and Deng, X and Guo, LP and Jiang, W and Zhan, QM and Lu, SH
CARCINOGENESIS, ISSN 0143-3334, 05/2019, Volume 40, Issue 5, pp. 669 - 679
Metformin showed chemopreventive effect on the carcinogenesis of ESCC induced by NMBzA in rats. Treatment with metformin led to activation of AMPK and... 
N-NITROSOMETHYLBENZYLAMINE | 2A3 | ONCOLOGY | GENES | TARGETS | AMPK | BLACK-RASPBERRIES | PREVENTS | CANCER | TUMORIGENESIS | CARCINOMA
Journal Article
Cell Death and Disease, ISSN 2041-4889, 06/2019, Volume 10, Issue 6, pp. 432 - 14
Transcription cofactor Yes-associated protein (YAP) plays an important role in cancer progression. Here, we found that Aurora A kinase expression was... 
Yes-associated protein | Proteins | Transcription | Autophagy | Lung cancer | Phagocytosis
Journal Article
by Yan, T and Cui, HY and Zhou, Y and Yang, B and Kong, PZ and Zhang, YC and Liu, YQ and Wang, B and Cheng, YK and Li, JY and Guo, SX and Xu, EW and Liu, HJ and Cheng, CX and Zhang, L and Chen, L and Zhuang, XF and Qian, Y and Yang, J and Ma, YC and Li, HY and Wang, F and Liu, J and Liu, XF and Su, D and Wang, Y and Sun, RF and Guo, SP and Li, YP and Cheng, XL and Liu, ZH and Zhan, QM and Cui, YP
NATURE COMMUNICATIONS, ISSN 2041-1723, 04/2019, Volume 10, Issue 1, pp. 1670 - 15
Journal Article
Journal Article
Molecular Oncology, ISSN 1574-7891, 04/2019, Volume 13, Issue 4, pp. 959 - 977
Breast cancer susceptibility gene 1 (BRCA1) has been implicated in modulating metabolism via transcriptional regulation. However, direct metabolic targets of... 
co‐repressor | ZBRK | BRCA | breast cancer | aspartate | GOT | ZBRK1 | BRCA1 | GOT2 | co-repressor | PROTEIN | CANCER | BREAST | REMOVAL | METABOLISM | ONCOLOGY | PROTEASOME | ANALYSIS TOOL | SUBUNIT
Journal Article
by Zhang, XJ and Chen, W and Yin, N and Dong, LJ and Fu, M and Zhan, QM and Tong, T
ONCOLOGY LETTERS, ISSN 1792-1074, 03/2019, Volume 17, Issue 3, pp. 2639 - 2646
Overexpressed in lung cancer 1 (OLC1) is a potential oncogene overexpressed in human lung cancer and in other types of malignant tumor. The elevated expression... 
ACTIVATION | overexpressed in lung cancer 1 | IST1 | cadherin 1 | cell-division cycle protein 20 | degradation | MECHANISMS | CANCER | CYTOKINESIS | destruction box | ONCOLOGY | POOR-PROGNOSIS | anaphase-promoting complex/cyclosome | OVER-EXPRESSION | CIGARETTE-SMOKE
Journal Article
EBioMedicine, ISSN 2352-3964, 03/2019, Volume 41, pp. 244 - 255
Targeting PLK1 has recently been proven as a viable therapeutic strategy against oesophageal squamous cell carcinom (ESCC). Therefore, this study aimed to... 
Pyroptosis | Combination | ESCC | PLK1 inhibitor | GSDME | MEDICINE, RESEARCH & EXPERIMENTAL | POLO | CHEMOTHERAPY | PHASE-II TRIAL | SELECTIVE INHIBITOR | GASDERMIN D | LYMPH-NODE METASTASIS | GASTRIC-CANCER | BI 2536 | DFNA5
Journal Article
EBioMedicine, ISSN 2352-3964, 03/2019, Volume 41, pp. 244 - 255
Background: Targeting PLK1 has recently been proven as a viable therapeutic strategy against oesophageal squamous cell carcinom (ESCC). Therefore, this study... 
Journal Article
by Zhao, ZT and Li, L and Du, PN and Ma, LY and Zhang, WM and Zheng, LL and Lan, B and Zhang, BL and Ma, F and Xu, B and Zhan, QM and Song, YM
THERANOSTICS, ISSN 1838-7640, 2019, Volume 9, Issue 5, pp. 1401 - 1416
Rationale: Triple-negative breast cancer (TNBC) is characterized by the absence of estrogen receptor alpha (ER-a), human epidermal growth factor receptor 2... 
MEDICINE, RESEARCH & EXPERIMENTAL | targeted therapy | triple-negative breast cancer | ACTIVATION | METASTASIS | ANGIOGENESIS | transcriptional regulation | IDENTIFICATION | GEMCITABINE | GROWTH-FACTOR RECEPTOR | ERBB-2 | INHIBITION | microRNA | EXPRESSION | NEOADJUVANT
Journal Article
PLoS Genetics, ISSN 1553-7390, 02/2019, Volume 15, Issue 2, p. e1007888
Brain metastasis (BM) is a major complication of lung adenocarcinoma (LAD). An investigation of the pathogenic mechanisms of BM, as well as the identification... 
BREAST-CANCER | SURVIVAL | NSCLC | MIRNA | GENETICS & HEREDITY | EXOSOME | CANCER STATISTICS | SERUM | CELL-GROWTH | NONINVASIVE BIOMARKERS | EXPRESSION | Adenocarcinoma | MicroRNA | Molecular genetics | Analysis | Genetic aspects | Diagnosis | Metastasis | Laboratories | Lung cancer | MiRNA | Melanoma | Oncology | Breast cancer | Kinases | Patients | Cell adhesion & migration | Metastases | Cell growth | Medical prognosis | MicroRNAs | Biomarkers | Tumorigenesis | Cell migration | Tumors | Apoptosis
Journal Article