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Genome Biology, ISSN 1474-7596, 05/2018, Volume 19, Issue 1, pp. 59 - 9
Nucleotide base editors in plants have been limited to conversion of cytosine to thymine. Here, we describe a new plant adenine base editor based on an evolved... 
SgRNA forms | Herbicide resistance | Wheat | Cas9-adenosine deaminase | Rice | sgRNA forms | CRISPR | RESISTANT | ENDONUCLEASE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | GENOMIC DNA | Flow cytometry | Adenosine | tRNA | Base pairs | Thymine | Protoplasts | Adenine | Genomes | Adenosine deaminase | Conversion | Efficiency | Point mutation | Cytosine | Mutation | Deoxyribonucleic acid--DNA
Journal Article
Nature Biotechnology, ISSN 1087-0156, 11/2018, Volume 36, Issue 10, pp. 950 - 950
Base editors (BEs) have been used to create C-to-T substitutions in various organisms. However, editing with rat APOBEC1-based BE3 is limited to a 5-nt... 
FUTURE | MAIZE | WHEAT | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DNA | Analysis | Plant genetics | Research | Proteins | Potatoes | Editors | Editing | Thymidine | Fusion protein | Wheat
Journal Article
Genome Biology, ISSN 1474-7596, 10/2017, Volume 18, Issue 1, pp. 191 - 7
High-fidelity SpCas9 variants (eSpCas9 and SpCas9-HF1) have been engineered to reduce off-target effects. We found that changes in guide RNA length induced... 
SYSTEM | CRISPR-CAS NUCLEASES | SPECIFICITY | ENDONUCLEASES | VERSATILE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | HUMAN-CELLS | GENETICS & HEREDITY | PLANTS | WHEAT | CLEAVAGE | RICE | Proteins | CRISPR | Fidelity | Engineering | tRNA | Genomes | Ribonucleic acid--RNA | Deoxyribonucleic acid--DNA | Plant cells
Journal Article
ISSN 2040-3364, 7/2019, Volume 11, Issue 29, pp. 138 - 1386
Contacts between graphene and two-dimensional (2D) semiconductors have been widely investigated because of their tunable Schottky barrier height (SBH) by means... 
Journal Article
Nanoscale, ISSN 2040-3364, 01/2019, Volume 11, Issue 29, pp. 13800 - 13806
Contacts between graphene and two-dimensional (2D) semiconductors have been widely investigated because of their tunable Schottky barrier height (SBH) by means... 
Interlayers | First principles | Electronic devices | Compressive properties | Semiconductors | Electric contacts | Graphene | Mathematical analysis | Graphical user interface | Contact resistance | Electric fields | Heterostructures
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 15836 - 8
A novel metamaterial structure consisting of multiple graphene/dielectric layers and metallic substrate is proposed to achieve the broadband absorption... 
PLASMONICS | ABSORPTION | OPTICS | PHOTONICS | MULTIDISCIPLINARY SCIENCES | CHALLENGES
Journal Article
Sensors (Switzerland), ISSN 1424-8220, 01/2018, Volume 18, Issue 1, p. 116
A plasmonic refractive index (RI) sensor based on metal-insulator-metal (MIM) waveguide coupled with concentric double rings resonator (CDRR) is proposed and... 
High figure of merit | Plasmonic sensor | Concentric double rings resonator | concentric double rings resonator | PARALLEL WAVE-GUIDES | FIBER | ELECTROCHEMISTRY | LABEL-FREE | CHEMISTRY, ANALYTICAL | plasmonic sensor | INSTRUMENTS & INSTRUMENTATION | FANO RESONANCES | MODE | high figure of merit | Insulators | Sensors | Detection | Resonators | Figure of merit | Refractivity
Journal Article
The Plant Journal, ISSN 0960-7412, 06/2018, Volume 94, Issue 5, pp. 857 - 866
Summary GW2 is emerging as a key genetic determinant of grain weight in cereal crops; it has three homoeologs (TaGW2‐A1, ‐B1 and ‐D1) in hexaploid common wheat... 
gene editing mutant | homoeolog | grain length | grain width | grain weight | grain protein content | Triticum aestivum | genetic interaction | pericarp | SIZE | WIDTH | PLANT SCIENCES | GENOMICS | GENE | EXPRESSION | Crop yields | Wheat | Gluten | Analysis | Proteins | Cereal crops | Parameters | Genetic control | Cell number | Grain | Data processing | Pericarp | Genetic modification | Mutants
Journal Article
Carbon, ISSN 0008-6223, 12/2019, Volume 154, pp. 350 - 356
Graphene-based metasurfaces have emerged as promising photoelectric devices for dynamically controlling the polarization and wavefront of electromagnetic... 
Broadband transmission | Military electronics industry | Machine vision | Graphene | Electromagnetic waves | Graphite | Electric waves | Electromagnetic radiation
Journal Article
by Bai, W and Yang, P and Huang, J and Chen, DB and Zhang, JJ and Zhang, ZJ and Yang, JB and Xu, B
SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2019, Volume 9, Issue 1, pp. 1 - 9
Metasurfaces draw everyone's attention because they can precisely control the phase, amplitude and polarization of emergent light to achieve light field... 
DIELECTRIC METASURFACES | PLASMONIC METASURFACES | GE2SB2TE5 | ACHROMATIC METALENS | LENSES | MULTIDISCIPLINARY SCIENCES | Optics | I.R. radiation | Integration | Efficiency
Journal Article
Nanoscale Research Letters, ISSN 1931-7573, 12/2018, Volume 13, Issue 1, p. 1
Based on first-principle calculations, the stability, electronic structure, optical absorption, and modulated electronic properties by different interlayer... 
Information storage and retrieval | Analysis | Electric fields | Electric properties
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, p. e69240
Berberine (BBR), an isoquinoline derivative alkaloid isolated from Chinese herbs, has a long history of uses for the treatment of multiple diseases, including... 
PROMOTER ACTIVITY | LUNG-CANCER | APOPTOSIS | INHIBITION | COX2 EXPRESSION | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER | DOWN-REGULATION | MELANOMA-CELLS | KAPPA-B | AMPK ACTIVATION | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - drug therapy | Apoptosis - drug effects | Cytochromes c - metabolism | Humans | Lung Neoplasms - metabolism | Carcinoma, Non-Small-Cell Lung - metabolism | Lung Neoplasms - pathology | NF-kappa B - metabolism | Antineoplastic Agents - therapeutic use | Vascular Endothelial Growth Factor A - metabolism | Transcription Factor AP-2 - metabolism | Berberine - pharmacology | Cell Movement - drug effects | Caspases - metabolism | Signal Transduction - drug effects | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Cyclooxygenase 2 - metabolism | Cell Line, Tumor | Telomerase - metabolism | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Berberine - therapeutic use | Carcinoma, Non-Small-Cell Lung - drug therapy | Cytochrome | Bcl-2 protein | Lung cancer | AKT protein | Cytosol | Cancer therapies | Cell morphology | Proteins | Angiogenesis | Signal transduction | Mitochondria | Cell growth | Inhibition | Vascular endothelial growth factor | Telomerase | Binding | Berberine | NF-κB protein | Medical treatment | 1-Phosphatidylinositol 3-kinase | Cytochrome c | Phytochemicals | Molecular modelling | Stem cells | Hypoxia | Cell migration | Cell proliferation | Phosphorylation | Bax protein | Laboratories | Cytology | Colorectal cancer | Raf protein | Oncology | Kinases | Pathways | Rodents | Translocation | Extracellular signal-regulated kinase | Poly(ADP-ribose) polymerase | Caspase | Non-small cell lung carcinoma | Nuclear transport | Signaling | Lungs | Medical prognosis | Cyclooxygenase-2 | Prostate cancer | Apoptosis | Tumors | Cancer
Journal Article
Applied Optics, ISSN 1559-128X, 12/2017, Volume 56, Issue 35, pp. 9814 - 9821
This paper presents a sheet of graphene-ribbon waveguide as a simple and ultra-compact splitter and filter in the mid-infrared waveband. The central wavelength... 
DESIGN | FILMS | AREA | SILICON-ON-INSULATOR | DIRECTIONAL COUPLER | MULTIMODE INTERFERENCE COUPLER | POLARIZATION SPLITTER | OPTICS | Usage | Light filters | Graphene | Optical properties | Waveguides | Research | Laser beams
Journal Article
by Zhang, ZJ and Yang, JB and Bai, W and Han, YX and He, X and Huang, J and Chen, DB and Xu, SY and Xie, WL
APPLIED OPTICS, ISSN 1559-128X, 09/2019, Volume 58, Issue 27, pp. 7392 - 7396
We numerically propose a hybrid metasurface (MS) to realize all-optical switch and logic gates in the shortwave infrared (SWIR) band. Such MS consists of one... 
GENERATION | OPTICS | PHASE-CHANGE MATERIALS | NONVOLATILE | Phase transformations | Fiber optic networks | Switching theory | Phase transitions | Short wave | Logic circuits | Response time | Optical switching | Optical communication | Silicon | Active control | Field programmable gate arrays | Gates
Journal Article
Applied Energy, ISSN 0306-2619, 10/2019, Volume 251, p. 113388
The energy management approach of hybrid electric vehicles has the potential to overcome the increasing energy crisis and environmental pollution by reducing... 
Hybrid electric tracked vehicle (HETV) | Hardware-in-loop simulation bench | Energy management | Fast Q-learning (FQL) algorithm | Online updating framework
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, p. e63872
Ursolic acid (UA), a natural pentacyclic triterpenoid carboxylic acid distributed in medical herbs, exerts antitumor effects and is emerging as a promising... 
CYCLOOXYGENASE-2 PROMOTER ACTIVATION | MULTIDISCIPLINARY SCIENCES | IN-VIVO | DOWN-REGULATION | INHIBITOR | TUMOR-GROWTH | DERIVATIVES | EXPRESSION | CELECOXIB | ANTITUMOR | BINDING | Triterpenes - pharmacology | Apoptosis - drug effects | Cytochromes c - metabolism | Humans | NF-kappa B - metabolism | E1A-Associated p300 Protein - metabolism | Protein Transport - drug effects | Dinoprostone - metabolism | Cell Movement - drug effects | Acetylation - drug effects | Caspases - metabolism | Signal Transduction - drug effects | Time Factors | Colonic Neoplasms - pathology | Cyclooxygenase 2 - metabolism | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Prevention | Proteins | COX-2 inhibitors | Care and treatment | Colon cancer | Prostaglandins E | Cancer cells | Development and progression | Metastasis | Health aspects | Apoptosis | Cancer | Cytochrome | AKT protein | Event-related potentials | Cytosol | Caspase-3 | Cancer therapies | Cell morphology | Anticancer properties | Signal transduction | Mitochondria | Cell growth | Surgery | Tumorigenesis | Inhibition | Acetylation | Carboxylic acids | Forensic pathology | Cytochrome c | Chemotherapy | Molecular modelling | Morphology | Stem cells | Nuclei (cytology) | Viability | Cell migration | Cell proliferation | Phosphorylation | Laboratories | Cytology | Colorectal cancer | Oncology | E-cadherin | Pathways | Rodents | Pretreatment | Colon | Translocation | Extracellular signal-regulated kinase | Poly(ADP-ribose) polymerase | Caspase | Celecoxib | Gelatinase B | Signaling | Acids | Antitumor activity | Cyclooxygenase-2 | Cytoplasm
Journal Article
RSC Advances, ISSN 2046-2069, 08/2018, Volume 8, Issue 49, pp. 27746 - 27753
A hybrid metal-graphene metamaterial (MM) is reported to achieve active control of broadband plasmon-induced transparency (PIT) in the THz region. The unit... 
ANALOG | CHEMISTRY, MULTIDISCIPLINARY | ELECTROMAGNETICALLY INDUCED TRANSPARENCY | Unit cell | Broadband | Graphene | Modulation | Metamaterials | Electric wire | Active control | Physics - Optics
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 3370 - 3370
Journal Article
Optics Letters, ISSN 0146-9592, 05/2016, Volume 41, Issue 10, pp. 2310 - 2313
A new filter structure and optical field modulator with ultra-high resolution based on plasmonic nano-cavity resonators is proposed and numerically... 
Waveguides | Plasmons | Holes | Etching | Nanostructure | Plasmonics | Resonators | Modulators
Journal Article