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1988, Di 1 ban., ISBN 9787505302563, iii, 3, 298
Book
歌曲, ISSN 0454-0816, 2017, Issue 5, pp. 34 - 37
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 09/2016, Volume 7, Issue 1, p. 12543
Two-dimensional (2D) nanoscale oxides have attracted research interest owing to their electronic, magnetic optical and catalytic properties. If they could be... 
EXFOLIATION | GRAPHENE OXIDE | TRANSISTORS | FILMS | PERFORMANCE | MULTIDISCIPLINARY SCIENCES | CRYSTALS | NANOSHEETS | FABRICATION | ANODE | LITHIUM-ION BATTERIES
Journal Article
Cancer Science, ISSN 1347-9032, 06/2016, Volume 107, Issue 6, pp. 782 - 790
Heat shock protein 90 (Hsp90) stabilizes a variety of proteins required for cancer cell survival and has been identified as a promising drug target for cancer... 
Hsp90 | Hop | imatinib resistance | Y‐632 | thiol oxidation | Y-632 | Thiol oxidation | Imatinib resistance | PROTEASOMAL DEGRADATION | CLINICAL DEVELOPMENT | ANTICANCER AGENT | MDA-MB-231 CELLS | POSTTRANSLATIONAL MODIFICATIONS | CHRONIC MYELOID-LEUKEMIA | BREAST-CANCER CELLS | COMPLEX-FORMATION | ONCOLOGY | SMALL-MOLECULE INHIBITORS | TARGETING HSP90 | Apoptosis - drug effects | Humans | Ubiquitin - metabolism | Drug Resistance, Neoplasm | Heat-Shock Proteins - antagonists & inhibitors | Proteolysis - drug effects | Sulfhydryl Compounds - metabolism | Protein Binding - drug effects | Female | Antineoplastic Agents - pharmacology | Acrylamides - pharmacology | Intracellular Space - drug effects | Imatinib Mesylate - pharmacology | Heat-Shock Proteins - metabolism | Mutant Proteins - genetics | Adenosine Triphosphatases - metabolism | Pyrimidines - pharmacology | Cell Adhesion - drug effects | Xenograft Model Antitumor Assays | Point Mutation | Fusion Proteins, bcr-abl - genetics | Animals | Cell Cycle Checkpoints - drug effects | HSP90 Heat-Shock Proteins - antagonists & inhibitors | Intracellular Space - metabolism | Cell Line, Tumor | HSP90 Heat-Shock Proteins - metabolism | Mice | Proteasome Endopeptidase Complex - metabolism | Ubiquitin | Antimitotic agents | Heat shock proteins | Thiols | Gene mutations | Antineoplastic agents | BCR protein | Hsp90 protein | Clinical trials | Science | Geldanamycin | Kinases | Drug resistance | Cancer therapies | Cell adhesion & migration | Cell growth | Epidermal growth factor | Cell adhesion | Cell cycle | Oxidation | Imatinib | Immunoglobulins | Cell survival | Cell division | Hsp70 protein | Antitumor activity | Software | Mutation | Binding sites | Adenosine triphosphatase | Apoptosis | Cancer | Original
Journal Article
Molecular Immunology, ISSN 0161-5890, 10/2019, Volume 114, pp. 114 - 122
As an important metabolite in cholesterol metabolism, dehydroepiandrosterone (DHEA) can modulate the immune function in animals and humans, but the underlying... 
MAPK Pathway | Dehydroepiandrosterone | Macrophages | Anti-inflammation | NF-κB Pathway
Journal Article
Molecular Immunology, ISSN 0161-5890, 10/2019, Volume 114, p. 114
As an important metabolite in cholesterol metabolism, dehydroepiandrosterone (DHEA) can modulate the immune function in animals and humans, but the underlying... 
Prevention | COX-2 inhibitors | Dehydroepiandrosterone | Safety and security measures | Metabolites | Interleukins | Nitric oxide | Escherichia coli | Inflammation | Hormones, Sex | Macrophages | Food
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 02/2012, Volume 120, Issue 3, pp. 461 - 472
J. Neurochem. (2012) 120, 461–472. Activation of microglia, the resident macrophages of the brain, around the amyloid plaques is a key hallmark of Alzheimer’s... 
NF‐κB | Alzheimer’s disease | microglia | resveratrol | TLR4 | NF-κB | Alzheimer's disease | Tumor Necrosis Factor-alpha - metabolism | Stilbenes - therapeutic use | Amyloid beta-Peptides - pharmacology | Humans | Tumor Necrosis Factor-alpha - genetics | Male | I-kappa B Proteins - metabolism | Stilbenes - pharmacology | I-kappa B Proteins - genetics | Alzheimer Disease - pathology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Drug Interactions | Time Factors | Inflammation Mediators - pharmacology | Statistics, Nonparametric | Toll-Like Receptors - metabolism | Disease Models, Animal | NF-KappaB Inhibitor alpha | Cytokines - metabolism | Microglia - drug effects | Alzheimer Disease - drug therapy | Presenilin-1 - genetics | Mice, Transgenic | Amyloid beta-Protein Precursor - genetics | Animals | Signal Transduction - drug effects | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Toll-Like Receptors - genetics | Lipopolysaccharides - pharmacology | Mice | Alzheimer Disease - genetics | Cell Line, Transformed | Brain | Cell culture | Animal models | Phosphorylation | Transcription | Clinical trials | beta -Amyloid | Macrophages | IKK protein | Lipopolysaccharides | Interleukin 6 | Cell activation | Resveratrol | Microglial cells | Polyphenols | Toll-like receptors | Amyloid | Stat1 protein | Plaques | Antiinflammatory agents | Oligomerization | Neurodegenerative diseases | Stat3 protein | Inflammation | TLR4 protein | Microglia | NF- Kappa B protein | Lymphocytes B | Tumor necrosis factor- alpha | STAT | lipopolysaccharide
Journal Article
Cancer Science, ISSN 1347-9032, 01/2014, Volume 105, Issue 1, pp. 117 - 125
Activating mutations in KIT have been associated with gastrointestinal stromal tumors (GISTs). The tyrosine kinase inhibitor imatinib mesylate has... 
gastrointestinal stromal tumors | flumatinib | Drug resistance | imatinib mesylate | sunitinib malate | Sunitinib malate | Flumatinib | Gastrointestinal stromal tumors | Imatinib mesylate | WILD-TYPE | ACTIVATION | TYROSINE KINASE | ACQUIRED-RESISTANCE | C-KIT | KINASE INHIBITOR | ONCOLOGY | HUMAN MASTOCYTOSIS | MUTATIONS | IMATINIB RESISTANCE | Gastrointestinal Stromal Tumors - enzymology | Drug Resistance, Neoplasm | Protein Kinase Inhibitors - adverse effects | Proto-Oncogene Proteins c-kit - antagonists & inhibitors | Antineoplastic Agents - adverse effects | Pyrroles - adverse effects | Female | Indoles - pharmacology | Proto-Oncogene Proteins c-kit - genetics | Antineoplastic Agents - pharmacology | Benzamides - pharmacology | Benzamides - adverse effects | Gastrointestinal Stromal Tumors - genetics | Pyrimidines - pharmacology | Random Allocation | Interleukin-3 - genetics | Imatinib Mesylate | Piperazines - adverse effects | Piperazines - pharmacology | Pyrroles - pharmacology | Animals | Indoles - adverse effects | Gastrointestinal Stromal Tumors - drug therapy | Mice, Nude | Aminopyridines - pharmacology | Fusion Proteins, bcr-abl - antagonists & inhibitors | Pyrimidines - adverse effects | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Protein Kinase Inhibitors - pharmacology | Mutation | Platelet-Derived Growth Factor - antagonists & inhibitors | Angiogenesis inhibitors | Analysis | Tumors | Tyrosine | BCR protein | Imatinib | Laboratories | Kinases | Epidermal growth factor | Molecular modelling | Mutagenesis | Stem cells | Protein-tyrosine kinase | Original
Journal Article
Journal of Computational Physics, ISSN 0021-9991, 02/2017, Volume 330, p. 1
A Riemann problem based method for solving two-medium flow including compressible and incompressible regions is presented. The material interface is advanced... 
Incompressible flow | Shock waves | Numerical analysis | Algorithms | Computational fluid dynamics | Fluid flow | Boundary conditions | Galerkin method | Computational physics | Compressible flow
Journal Article
BMC Genomics, ISSN 1471-2164, 01/2018, Volume 19, Issue 1, pp. 29 - 15
Background: Chicken embryos are widely used as a model for studies of obesity; however, no detailed information is available about the dynamic changes of... 
Model | Obesity | ITRAQ | Proteomics | Chicken embryo | QUANTITATION | LOCI | SACCHAROMYCES-CEREVISIAE | GENE | GLUCONEOGENESIS | CLONING | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DISEASE | GENETICS & HEREDITY | iTRAQ | COMPLICATIONS | ACETYL-COA SYNTHETASE | EXPRESSION | Embryonic development | Chickens | Physiological aspects | Genetic aspects | Models | Research | Type 2 diabetes | Proteins | Glucose metabolism | Insulin resistance | Fatty acids
Journal Article
Nanoscale, ISSN 2040-3364, 01/2018, Volume 10, Issue 8, pp. 3639 - 3643
Since the late 1980s, low molecular weight gelators (LMWGs) based on different classes of natural products have been reported. Until 2011, pure natural LMWGs... 
Organisms | Low molecular weights | Natural products | Gelation | Steroids
Journal Article