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Chemical Research in Toxicology, ISSN 0893-228X, 09/2008, Volume 21, Issue 9, pp. 1814 - 1822
In vitro covalent binding assessments of drugs have been useful in providing retrospective insights into the association between drug metabolism and a... 
ACYL GLUCURONIDES | CHEMISTRY, MEDICINAL | PROTEIN | RAT | REACTIVE METABOLITES | TIENILIC ACID | HEPATIC-NECROSIS | BIOACTIVATION | IDENTIFICATION | CHEMISTRY, MULTIDISCIPLINARY | MASS-SPECTROMETRY | TOXICOLOGY | HUMAN URINE | Buspirone - chemistry | Raloxifene Hydrochloride - pharmacology | Thiazoles - metabolism | Acetaminophen - metabolism | Humans | Microsomes, Liver - metabolism | Indomethacin - metabolism | Simvastatin - pharmacology | Diclofenac - chemistry | Thiazines - metabolism | Propranolol - pharmacology | Toxicity Tests - methods | Binding Sites | Simvastatin - metabolism | Microsomes, Liver - chemistry | Indomethacin - pharmacology | Paroxetine - metabolism | Raloxifene Hydrochloride - metabolism | Triazoles - metabolism | Ticrynafen - metabolism | Paroxetine - pharmacology | Diclofenac - metabolism | Paroxetine - chemistry | Diphenhydramine - pharmacology | Diclofenac - pharmacology | Triazoles - chemistry | Buspirone - metabolism | Ticrynafen - pharmacology | Structure-Activity Relationship | Buspirone - pharmacology | Hepatocytes - metabolism | Dose-Response Relationship, Drug | Carbamazepine - chemistry | Diphenhydramine - metabolism | Acetaminophen - pharmacology | Microsomes, Liver - drug effects | Propranolol - metabolism | Carbamazepine - metabolism | Thiazines - pharmacology | Molecular Structure | Drug Evaluation, Preclinical | Hepatocytes - drug effects | Carbamazepine - pharmacology | Simvastatin - chemistry | Acetaminophen - chemistry | Ticrynafen - chemistry | Propranolol - chemistry | Diphenhydramine - chemistry | Thiazines - chemistry | Triazoles - pharmacology | Indomethacin - chemistry | Thiazoles - chemistry | Thiazoles - pharmacology | Raloxifene Hydrochloride - chemistry | Index Medicus
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 12/2008, Volume 18, Issue 23, pp. 6071 - 6077
Journal Article
Journal Article
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 11/2007, Volume 35, Issue 11, pp. 2111 - 2118
The role of transporters in the disposition of (+)-2-[4-({[2-(benzo[1,3]dioxol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid... 
IN-VITRO | CYCLOSPORINE-A | MOLECULAR-IDENTIFICATION | BILIARY-EXCRETION | FEXOFENADINE | ORGANIC ANION | PHARMACOLOGY & PHARMACY | RESISTANCE-ASSOCIATED PROTEIN-2 | HEPATIC-UPTAKE | MYCOPHENOLIC-ACID | POLYPEPTIDE | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Organic Anion Transporters, Sodium-Independent - genetics | Propionates - metabolism | Cricetulus | Rats, Wistar | Pyridines - chemistry | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Pyridines - pharmacokinetics | Bile - metabolism | Male | Hepatocytes - metabolism | Neoplasm Proteins - metabolism | Organic Anion Transporters - metabolism | Hepatocytes - cytology | Organic Anion Transporters - genetics | Transfection | ATP-Binding Cassette Transporters - genetics | Membrane Transport Proteins - genetics | Organic Anion Transporters, Sodium-Independent - metabolism | Rats, Mutant Strains | Phosphodiesterase 4 Inhibitors | ATP-Binding Cassette Transporters - metabolism | Membrane Transport Proteins - metabolism | Multidrug Resistance-Associated Proteins - genetics | Molecular Structure | Phosphodiesterase Inhibitors - chemistry | Neoplasm Proteins - genetics | CHO Cells | Cell Line | Propionates - chemistry | Cricetinae | Phosphodiesterase Inhibitors - pharmacokinetics | Rats | Propionates - pharmacokinetics | Rats, Sprague-Dawley | Animals | Pyridines - metabolism | Phosphodiesterase Inhibitors - metabolism | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | ATP Binding Cassette Transporter, Sub-Family B | Multidrug Resistance-Associated Proteins - metabolism
Journal Article
Drug Metabolism and Pharmacokinetics, ISSN 1347-4367, 2011, Volume 26, Issue 3, pp. 266 - 279
The metabolism of 3,4-dihydro-7-[4-(1-naphthalenyl)-1-piperazinyl]butoxy]-1,8-naphthyridin-2(1H)-one (NPBN) was investigated in rats. Animals were administered... 
metabolism | rat | N-dearylation | dopamine D2 partial agonist | glutathione | partial agonist | Dopamine D | Rat | Metabolism | Glutathione | dopamine D-2 partial agonist | DRUG | CYTOCHROME-P450 | ANTIDEPRESSANT | BIOACTIVATION | MECHANISMS | DEMETHYLATION REACTIONS | NEFAZODONE | ATOM | PHARMACOLOGY & PHARMACY | ARIPIPRAZOLE | Epoxy Compounds - metabolism | Antipsychotic Agents - blood | Area Under Curve | Dopamine Antagonists - pharmacokinetics | Glutathione - metabolism | Microsomes, Liver - metabolism | Male | Piperazines - metabolism | Chromatography, High Pressure Liquid | Sulfuric Acid Esters - metabolism | Glucuronides - blood | Naphthyridines - urine | Dopamine Antagonists - urine | Glucuronides - metabolism | Spectrometry, Mass, Electrospray Ionization | Dopamine Antagonists - metabolism | Female | Molecular Structure | Piperazines - urine | Piperazines - pharmacokinetics | Dopamine Antagonists - blood | Piperazines - blood | Naphthyridines - blood | Antipsychotic Agents - urine | Drug Partial Agonism | Glutathione - analogs & derivatives | Hydroxylation | Magnetic Resonance Spectroscopy | Oxidation-Reduction | Dealkylation | Urine - chemistry | Rats | Antipsychotic Agents - pharmacokinetics | Rats, Sprague-Dawley | Animals | Feces - chemistry | Naphthyridines - pharmacokinetics | Antipsychotic Agents - metabolism | Dopamine D2 Receptor Antagonists | Naphthyridines - metabolism
Journal Article
Journal Article
Journal of medicinal chemistry, ISSN 0022-2623, 07/2006, Volume 49, Issue 14, p. 4425
Journal Article
Industrial Marketing Management, ISSN 0019-8501, 11/1996, Volume 25, Issue 6, p. 545
Journal Article
Industrial Marketing Management, ISSN 0019-8501, 11/1996, Volume 25, Issue 6, p. 545
  Cross-functional coordination and collaboration between R&D and marketing is crucial to the success of the new product development process. By understanding... 
Studies | R&D | Cooperation | Organizational structure | Product development | Information control | Marketing
Journal Article
by Aaboud, M and Aad, G and Abbott, B and Abdinov, O and Abeloos, B and Abhayasinghe, D.K and Abidi, S.H and AbouZeid, O.S and Abraham, N.L and Abramowicz, H and Abreu, H and Abulaiti, Y and Acharya, B.S and Adachi, S and Adamczyk, L and Adelman, J and Adersberger, M and Adiguzel, A and Adye, T and Affolder, A.A and Afik, Y and Agheorghiesei, C and Aguilar-Saavedra, J.A and Ahmadov, F and Aielli, G and Akatsuka, S and Åkesson, T.P.A and Akilli, E and Akimov, A.V and Alberghi, G.L and Albert, J and Albicocco, P and Alconada Verzini, M.J and Alderweireldt, S and Aleksa, M and Aleksandrov, I.N and Alexa, C and Alexopoulos, T and Alhroob, M and Ali, B and Aliev, M and Alimonti, G and Alison, J and Alkire, S.P and Allaire, C and Allbrooke, B.M.M and Allen, B.W and Allport, P.P and Aloisio, A and Alonso, A and Alonso, F and Alpigiani, C and Alshehri, A.A and Alstaty, M.I and Alvarez Gonzalez, B and Álvarez Piqueras, D and Alviggi, M.G and Amadio, B.T and Amaral Coutinho, Y and Ambroz, L and Amelung, C and Amidei, D and Amor Dos Santos, S.P and Amoroso, S and Amrouche, C.S and Anastopoulos, C and Ancu, L.S and Andari, N and Andeen, T and Anders, J.K and Anders, C.F and Anderson, K.J and Andreazza, A and Andrei, V and Anelli, C.R and Angelidakis, S and Angelozzi, I and Angerami, A and Anisenkov, A.V and Annovi, A and Antel, C and Anthony, M.T and Antonelli, M and Antrim, D.J.A and Anulli, F and Aoki, M and Aperio Bella, L and Arabidze, G and Araque, J.P and Araujo Ferraz, V and Araujo Pereira, R and Arce, A.T.H and Ardell, R.E and Arduh, F.A and Arguin, J-F and Argyropoulos, S and Armbruster, A.J and Armitage, L.J and Armstrong, A and Arnaez, O and ... and ATLAS Collaboration and Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States) and Partikel- och astropartikelfysik and Skolan för teknikvetenskap (SCI) and KTH and Fysik
Physics Letters B, ISSN 0370-2693, 09/2018, Volume 784, Issue C, pp. 173 - 191
The observation of Higgs boson production in association with a top quark pair ( ), based on the analysis of proton–proton collision data at a centre-of-mass... 
PHYSICS, NUCLEAR | SEARCH | ASTRONOMY & ASTROPHYSICS | PHYSICS, PARTICLES & FIELDS | Physics - High Energy Physics - Experiment | PHYSICS OF ELEMENTARY PARTICLES AND FIELDS | Fysik | Subatomär fysik | Physical Sciences | Subatomic Physics | Naturvetenskap | Natural Sciences
Journal Article
by Aaboud, M and Aad, G and Abbott, B and Abdinov, O and Abeloos, B and Abidi, S.H and AbouZeid, O.S and Abraham, N.L and Abramowicz, H and Abreu, R and Abreu, H and Abulaiti, Y and Acharya, B.S and Adachi, S and Adamczyk, L and Adelman, J and Adersberger, M and Adye, T and Affolder, A.A and Afik, Y and Agheorghiesei, C and Aguilar-Saavedra, J.A and Ahlen, S.P and Ahmadov, F and Aielli, G and Akatsuka, S and Akerstedt, H and Åkesson, T.P.A and Akilli, E and Akimov, A.V and Alberghi, G.L and Albert, J and Albicocco, P and Alconada Verzini, M.J and Alderweireldt, S.C and Aleksa, M and Aleksandrov, I.N and Alexa, C and Alexander, G and Alexopoulos, T and Alhroob, M and Ali, B and Aliev, M and Alimonti, G and Alison, J and Alkire, S.P and Allbrooke, B.M.M and Allen, B.W and Allport, P.P and Aloisio, A and Alonso, A and Alonso, F and Alpigiani, C and Alshehri, A.A and Alstaty, M.I and Alvarez Gonzalez, B and Álvarez Piqueras, D and Alviggi, M.G and Amadio, B.T and Amaral Coutinho, Y and Amelung, C and Amidei, D and Amor Dos Santos, S.P and Amoroso, S and Anastopoulos, C and Ancu, L.S and Andari, N and Andeen, T and Anders, J.K and Anders, C.F and Anderson, K.J and Andreazza, A and Andrei, V and Angelidakis, S and Angelozzi, I and Angerami, A and Anisenkov, A.V and Anjos, N and Annovi, A and Antel, C and Antonelli, M and Antonov, A and Antrim, D.J and Anulli, F and Aoki, M and Aperio Bella, L and Arabidze, G and Arai, Y and Araque, J.P and Araujo Ferraz, V and Arce, A.T.H and Ardell, R.E and Arduh, F.A and Arguin, J-F and Argyropoulos, S and Arik, M and Armbruster, A.J and Armitage, L.J and Arnaez, O and Arnold, H and ... and Atlas Collaboration and SLAC National Accelerator Lab., Menlo Park, CA (United States) and Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States) and Partikel- och astropartikelfysik and Skolan för teknikvetenskap (SCI) and KTH and Fysik
Physics Letters B, ISSN 0370-2693, 04/2018, Volume 779, Issue C, pp. 24 - 45
Journal Article