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The American Journal of Human Genetics, ISSN 0002-9297, 03/2012, Volume 90, Issue 3, pp. 467 - 477
Manganese is essential for several metabolic pathways but becomes toxic in excessive amounts. Manganese levels in the body are therefore tightly regulated, but... 
TRANSPORTER | MANGANESE | CIRRHOSIS | GENES | GENETICS & HEREDITY | IDENTIFICATION | ZNT-1 | EXPRESSION | ZINC | FAMILY | Manganese Poisoning - genetics | Zinc Transporter 8 | Humans | Middle Aged | Molecular Sequence Data | Male | Brain - metabolism | Cation Transport Proteins - metabolism | Membrane Transport Proteins - genetics | Chromosome Mapping - methods | Cation Transport Proteins - genetics | Female | Membrane Transport Proteins - metabolism | Parkinsonian Disorders - genetics | Tumor Cells, Cultured | Frameshift Mutation - genetics | Amino Acid Sequence | Genetic Predisposition to Disease | Liver - metabolism | Genes, Recessive | Hep G2 Cells | Immunohistochemistry - methods | Homozygote | Sequence Alignment - methods | Phenotype | Manganese - metabolism | Metabolic Diseases - metabolism | Metabolic Diseases - genetics | Aged | Manganese Poisoning - metabolism | Parkinsonism | Liver diseases | Gene mutations | Causes of | Genetic aspects | Dystonia | Research | Manganese compounds | Physiology | Mutation | Genomics | Neurological disorders | Index Medicus | Brain | Basal ganglia | Central nervous system diseases | Frameshift mutation | Nervous system | Cytosol | Fatty liver | Polycythemia | Substrate specificity | Chelation | Cations | Metabolic pathways | Gene mapping | steatosis | Movement disorders | Manganese
Journal Article
The Lancet Neurology, ISSN 1474-4422, 07/2018, Volume 17, Issue 7, pp. 597 - 608
Most patients with Parkinson's disease, Parkinson's disease dementia, and dementia with Lewy bodies do not carry mutations in known disease-causing genes. The... 
DIAGNOSIS | MULTICENTER | MANAGEMENT | VPS35 | GLUCOCEREBROSIDASE MUTATIONS | ASSOCIATION | CLINICAL NEUROLOGY | FEATURES | REVEALS | Parkinson Disease - complications | Genome-Wide Association Study | Humans | Middle Aged | RNA, Messenger - genetics | Male | Dementia - epidemiology | Parkinson Disease - genetics | Dementia - genetics | LDL-Receptor Related Proteins - genetics | Lewy Body Disease - epidemiology | Pluripotent Stem Cells - metabolism | Dementia - etiology | Lewy Body Disease - genetics | Pedigree | Brain - pathology | Parkinson Disease - epidemiology | Family | Female | Heterozygote | Italy | RNA, Messenger - chemistry | Chromosomes, Human, Pair 14 - genetics | Genetic Linkage | Genetic research | Genetic aspects | Analysis | Genomics | Dementia | Parkinson's disease | Laboratories | Neuropathology | Immunocytochemistry | Genes | Parkinsons disease | Aneurysm | Genomes | Proteins | Neurodegeneration | Autopsy | Dementia disorders | Aorta | Chromosome 14 | Movement disorders | Deoxyribonucleic acid--DNA | Linkage analysis | Neurodegenerative diseases | Therapeutic applications | Gene expression | Lewy bodies | Genetic variance | Pathology | Cycloheximide | Brain research | Molecular modelling | Pluripotency | mRNA stability | Index Medicus | Neurologi | Clinical Medicine | Neurology | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 5410 - 5410
Olfactory neuroblastoma (ONB) is a rare malignant neoplasm arising in the upper portion of the sinonasal cavity. To better understand the genetic bases for... 
SURVIVAL | GENE | LAMA2 | ESTHESIONEUROBLASTOMA | CGH | MULTIDISCIPLINARY SCIENCES | PATTERNS | HYBRIDIZATION | MICE | MUTATIONS | CANCER | Genomic analysis | Clonal deletion | Genes | Deletion | Genomes | Single-nucleotide polymorphism | Neuroblastoma | Dystrophin | Polymorphism | Tumors | Gene sequencing
Journal Article
Developmental Neurobiology, ISSN 1932-8451, 11/2016, Volume 76, Issue 11, pp. 1266 - 1274
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2012, Volume 7, Issue 11, pp. e48911 - e48911
textabstractRecessive mutations in the F-box only protein 7 gene (FBXO7) cause PARK15, a Mendelian form of early-onset, levodopa-responsive parkinsonism with... 
LOCALIZATION | PINK1 FUNCTION | TRANSPORTER | MULTIDISCIPLINARY SCIENCES | TOXICITY | ATP13A2 | ALPHA-SYNUCLEIN | MUTATIONS | EXPRESSION | EMBRYOS | PARKINSONS-DISEASE | Protein Structure, Tertiary | Exons | Introns | Humans | Zebrafish | RNA, Messenger - metabolism | Brain - metabolism | Immunohistochemistry - methods | Parkinsonian Disorders - metabolism | Locomotion | Phenotype | Animals | F-Box Proteins - physiology | In Situ Hybridization | Apomorphine - pharmacology | Dopamine Antagonists - pharmacology | Body Patterning | Domperidone - pharmacology | Neurons - metabolism | F-Box Proteins - genetics | Dopamine - metabolism | Disease Models, Animal | Expressed Sequence Tags | Tyrosine | Embryonic development | Dopamine | Parkinson's disease | RNA | Neurons | Phenols | Tumor proteins | Genetic translation | Pattern formation | Brain | Animal models | Basal ganglia | Pathogenesis | p53 Protein | Genes | Parkinsons disease | Homology | Amino acids | mRNA | Hybridization | Tyrosine 3-monooxygenase | Defects | Proteins | Neurodegeneration | Rodents | Coinjection | Dopamine transporter | Levodopa | Age | Movement disorders | Dopamine receptors | Splicing | Abnormalities | Hydroxylase | Central nervous system diseases | Pharmacology | Injection | Protein deficiency | Gene expression | Embryos | Chemical compounds | Apomorphine | Protein expression | Genetic engineering | Mutation | Alzheimers disease | Human behavior | Transporter | Index Medicus
Journal Article
The Journal of Engineering, ISSN 2051-3305, 11/2018, Volume 2018, Issue 16, pp. 1637 - 1644
Journal Article
Zhineng Xitong Xuebao = CAAI Transactions on Intelligent Systems, ISSN 1673-4785, 01/2017, Volume 12, Issue 6, p. 883
The dominance relation rough set model is the main method of data mining when researching order informa-tion systems. In this paper, we attempt to enrich the... 
Fuzzy logic | Fuzzy sets | Rough set models | Norms | Dominance | Production scheduling | Data mining | Information systems | Fuzzy systems
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 05/2015, Volume 35, Issue 20, pp. 7850 - 7865
Successful myelin repair in the adult CNS requires the robust and timely production of myelin proteins to generate new myelin sheaths. The underlying... 
Journal Article
Cancer Research, ISSN 0008-5472, 06/2006, Volume 66, Issue 12, pp. 6361 - 6369
Optimal reexpression of most genes silenced through promoter methylation requires the sequential application of DNA methyltransferase inhibitors followed by... 
ACUTE-LEUKEMIA | CYTIDINE DEAMINASE GENE | CPG ISLAND METHYLATION | ONCOLOGY | ARA-C SENSITIVITY | HYPOMETHYLATING AGENT | COLORECTAL-CANCER | RISK MYELODYSPLASTIC SYNDROME | LOW-DOSE 5-AZA-2'-DEOXYCYTIDINE | ORAL SODIUM PHENYLBUTYRATE | ELDERLY-PATIENTS | Azacitidine - adverse effects | Humans | Leukemia, Myeloid - genetics | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Phenylbutyrates - adverse effects | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | DNA (Cytosine-5-)-Methyltransferases - antagonists & inhibitors | Feasibility Studies | Myelodysplastic Syndromes - enzymology | Dose-Response Relationship, Drug | Phenylbutyrates - pharmacokinetics | Phenylbutyrates - administration & dosage | Aged, 80 and over | Female | Myelodysplastic Syndromes - drug therapy | Azacitidine - administration & dosage | Promoter Regions, Genetic | Acute Disease | Azacitidine - pharmacokinetics | Myelodysplastic Syndromes - metabolism | Histone Deacetylases - genetics | Leukemia, Myeloid - enzymology | Treatment Outcome | DNA (Cytosine-5-)-Methyltransferases - genetics | Leukemia, Myeloid - drug therapy | Acetylation - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Leukemia, Myeloid - metabolism | Aged | Histone Deacetylase Inhibitors | Myelodysplastic Syndromes - genetics | Histones - metabolism | DNA Methylation - drug effects | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2011, Volume 6, Issue 2, pp. e16983 - e16983
textabstractMutations in the F-box only protein 7 gene (FBXO7) cause PARK15, an autosomal recessive neurodegenerative disease presenting with severe... 
DISEASE | BIOLOGY | F-BOX PROTEINS | FUNCTIONAL DOMAINS | MUTATIONS | IDENTIFICATION | INHIBITOR | FAMILY | Neurons - pathology | Humans | Male | Neurons - cytology | Nerve Net - cytology | Brain - metabolism | Parkinsonian Disorders - metabolism | Cell Nucleus - metabolism | Protein Isoforms - metabolism | HEK293 Cells | Aged, 80 and over | Parkinsonian Disorders - genetics | Neurons - metabolism | Cell Line | Brain - cytology | F-Box Proteins - metabolism | Gene Expression Regulation | Nerve Net - pathology | Protein Transport | Animals | Parkinsonian Disorders - pathology | Intracellular Space - metabolism | Nerve Net - metabolism | Brain - pathology | Aged | Mice | Mutation | F-Box Proteins - genetics | Protein Isoforms - genetics | Proteins | Family | Nervous system diseases | Parkinson's disease | Cells | Neurophysiology | Cerebellum | Brain | Biotechnology | Transcription factors | Basal ganglia | Cerebral cortex | Pathogenesis | Substantia nigra | Amino acids | Kinases | Missense mutation | Neurodegeneration | Rodents | Cell cycle | Fibroblasts | Genetics | Levodopa | Localization | Profilin | Movement disorders | Dopamine receptors | Dopamine | Neurodegenerative diseases | Neurons | Cloning | Cortex | Globus pallidus | Central nervous system diseases | Patients | N-Terminus | Cell lines | Isoforms | Nuclei (cytology) | Skin | Immunoreactivity | Position (location) | Alzheimers disease | Apoptosis | Index Medicus
Journal Article