Journal of Cellular Physiology, ISSN 0021-9541, 04/2018, Volume 233, Issue 4, pp. 3648 - 3659
The main pathological characteristics of chronic glomerulonephritis (CGN) are diffuse mesangial cells proliferation and inflammatory responses. Our previous...
chronic glomerulonephritis | AKT/GSK signaling pathway | mesangial cells | miR‐145‐5p | CXCL16 | miR-145-5p | PHYSIOLOGY | PROTEIN | RAT | AKT | CELL-PROLIFERATION | MODEL | MESENCHYMAL TRANSITION | CELL BIOLOGY | HYPERTROPHY | GSK signaling pathway | KIDNEY | NF-KAPPA-B | EXPRESSION | Cell Proliferation - genetics | Animals | Rats | MicroRNAs - genetics | Signal Transduction - genetics | Mesangial Cells - metabolism | Proto-Oncogene Proteins c-akt - metabolism | RNA Interference - physiology | Chemokine CXCL16 - metabolism | Down-Regulation - genetics | RNA, Small Interfering - metabolism | Albumin | Inflammation | Analysis | Protein binding | Cell proliferation | Glomerulonephritis | Bovine serum albumin | Renal function | AKT protein | Serum albumin | Interleukin 6 | Signal transduction | Signaling | Cell growth | Interleukin 2 | 3' Untranslated regions | Tumor necrosis factor | S phase | Rodents | Cell cycle | Interleukin 1 | CXCL16 protein | Mesangial cells | In vivo methods and tests | Inhibition | G1 phase
chronic glomerulonephritis | AKT/GSK signaling pathway | mesangial cells | miR‐145‐5p | CXCL16 | miR-145-5p | PHYSIOLOGY | PROTEIN | RAT | AKT | CELL-PROLIFERATION | MODEL | MESENCHYMAL TRANSITION | CELL BIOLOGY | HYPERTROPHY | GSK signaling pathway | KIDNEY | NF-KAPPA-B | EXPRESSION | Cell Proliferation - genetics | Animals | Rats | MicroRNAs - genetics | Signal Transduction - genetics | Mesangial Cells - metabolism | Proto-Oncogene Proteins c-akt - metabolism | RNA Interference - physiology | Chemokine CXCL16 - metabolism | Down-Regulation - genetics | RNA, Small Interfering - metabolism | Albumin | Inflammation | Analysis | Protein binding | Cell proliferation | Glomerulonephritis | Bovine serum albumin | Renal function | AKT protein | Serum albumin | Interleukin 6 | Signal transduction | Signaling | Cell growth | Interleukin 2 | 3' Untranslated regions | Tumor necrosis factor | S phase | Rodents | Cell cycle | Interleukin 1 | CXCL16 protein | Mesangial cells | In vivo methods and tests | Inhibition | G1 phase
Journal Article
数学教学, ISSN 0488-7387, 2017, Issue 5, pp. F0004 - F0004
Journal Article
成功营销, ISSN 1008-1429, 2016, Issue 12, pp. 74 - 75
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FOOD & FUNCTION, ISSN 2042-6496, 9/2019, Volume 1, Issue 9, pp. 662 - 673
Depression is a mental disorder that brings severe burdens to patients and their families. Neuroinflammation and neurotrophins are involved in depression....
PROTEIN | NEUROINFLAMMATION | ANXIETY | NEUROTROPHIC FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOOD SCIENCE & TECHNOLOGY | AUTOPHAGY | STRESS | PATHOPHYSIOLOGY | Calcium | Mental disorders | Calcium metabolism | Pharmacology | Inflammation | Mental depression | Metabolism | Autophagy | Western blotting | Microglia | Lipopolysaccharides | Calcium signalling | Alkaloids | Tea | Signaling | Nitrogen metabolism | Brain-derived neurotrophic factor | Nitric oxide | Neurotrophins | Phagocytosis
PROTEIN | NEUROINFLAMMATION | ANXIETY | NEUROTROPHIC FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOOD SCIENCE & TECHNOLOGY | AUTOPHAGY | STRESS | PATHOPHYSIOLOGY | Calcium | Mental disorders | Calcium metabolism | Pharmacology | Inflammation | Mental depression | Metabolism | Autophagy | Western blotting | Microglia | Lipopolysaccharides | Calcium signalling | Alkaloids | Tea | Signaling | Nitrogen metabolism | Brain-derived neurotrophic factor | Nitric oxide | Neurotrophins | Phagocytosis
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 11/2019, Volume 169, p. 113619
Immunoglobulin A nephropathy (IgAN) is an autoimmune kidney disease with complex pathogenesis leading to end-stage renal damage. The prime pathological...
IgA nephropathy | Hydroxychloroquine | Exosomes | Nuclear factor-κB | NLRP3 inflammasome | Artemisinin
IgA nephropathy | Hydroxychloroquine | Exosomes | Nuclear factor-κB | NLRP3 inflammasome | Artemisinin
Journal Article
International Immunopharmacology, ISSN 1567-5769, 04/2016, Volume 33, pp. 33 - 41
Zhen-wu-tang (ZWT), a traditional Chinese compound formula recorded in the , has significant inhibitory effects on inflammatory damage and oxidative lesions in...
Zhen-wu-tang | Glomerulonephritis | Inflammatory responses | Advanced glycation end products | OXIDATIVE STRESS | TRANSCRIPTION | RENAL-FUNCTION | RECEPTOR | MODEL | IMMUNOLOGY | PATHOGENIC ROLE | NEPHROPATHY | LIPOPOLYSACCHARIDE | PHARMACOLOGY & PHARMACY | CHRONIC KIDNEY-DISEASE | GLYCATION END-PRODUCTS | Tumor Necrosis Factor-alpha - metabolism | Superoxide Dismutase - genetics | Medicine, Chinese Traditional | Receptor for Advanced Glycation End Products - metabolism | Rats | Male | NF-kappa B - metabolism | Rats, Sprague-Dawley | Animals | Signal Transduction - drug effects | Glomerulonephritis, Membranous - drug therapy | Interleukin-1beta - metabolism | Serum Albumin, Bovine | Anti-Inflammatory Agents - therapeutic use | Oxidative Stress - drug effects | Receptor for Advanced Glycation End Products - genetics | Drugs, Chinese Herbal - therapeutic use | Interleukin-6 - metabolism | Superoxide Dismutase - metabolism | Disease Models, Animal
Zhen-wu-tang | Glomerulonephritis | Inflammatory responses | Advanced glycation end products | OXIDATIVE STRESS | TRANSCRIPTION | RENAL-FUNCTION | RECEPTOR | MODEL | IMMUNOLOGY | PATHOGENIC ROLE | NEPHROPATHY | LIPOPOLYSACCHARIDE | PHARMACOLOGY & PHARMACY | CHRONIC KIDNEY-DISEASE | GLYCATION END-PRODUCTS | Tumor Necrosis Factor-alpha - metabolism | Superoxide Dismutase - genetics | Medicine, Chinese Traditional | Receptor for Advanced Glycation End Products - metabolism | Rats | Male | NF-kappa B - metabolism | Rats, Sprague-Dawley | Animals | Signal Transduction - drug effects | Glomerulonephritis, Membranous - drug therapy | Interleukin-1beta - metabolism | Serum Albumin, Bovine | Anti-Inflammatory Agents - therapeutic use | Oxidative Stress - drug effects | Receptor for Advanced Glycation End Products - genetics | Drugs, Chinese Herbal - therapeutic use | Interleukin-6 - metabolism | Superoxide Dismutase - metabolism | Disease Models, Animal
Journal Article
International Immunopharmacology, ISSN 1567-5769, 05/2019, Volume 70, pp. 313 - 323
Immunoglobulin A nephropathy (IgAN) is an autoimmune kidney disease with complex pathogenesis leading to end-stage renal damage. The crucial pathological...
IgA nephropathy | Hydroxychloroquine | T cells | Artemisinin | RHEUMATOID-ARTHRITIS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACTIVATION | CYTOKINES | PROLIFERATION | IMMUNOLOGY | DECREASES | B-CELLS | PATHWAY | PHARMACOLOGY & PHARMACY | T-CELLS | Disease susceptibility | Kidney diseases | Immunoglobulin A | Cell differentiation | Cell proliferation | End-stage renal disease | Therapy | Pathogenesis | Helper cells | Medical services | Lymphocytes T | Immunosuppressive agents | Lymphocytes | Rodents | Antigen-antibody complexes | Spleen | Kidneys | Immunomodulation | Traditional Chinese medicine | Pharmacology | Inflammation | CD4 antigen | Herbal medicine | Immunosuppression | Complement component C3 | Morphology | Autoimmune diseases | Differentiation | Immunofluorescence
IgA nephropathy | Hydroxychloroquine | T cells | Artemisinin | RHEUMATOID-ARTHRITIS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACTIVATION | CYTOKINES | PROLIFERATION | IMMUNOLOGY | DECREASES | B-CELLS | PATHWAY | PHARMACOLOGY & PHARMACY | T-CELLS | Disease susceptibility | Kidney diseases | Immunoglobulin A | Cell differentiation | Cell proliferation | End-stage renal disease | Therapy | Pathogenesis | Helper cells | Medical services | Lymphocytes T | Immunosuppressive agents | Lymphocytes | Rodents | Antigen-antibody complexes | Spleen | Kidneys | Immunomodulation | Traditional Chinese medicine | Pharmacology | Inflammation | CD4 antigen | Herbal medicine | Immunosuppression | Complement component C3 | Morphology | Autoimmune diseases | Differentiation | Immunofluorescence
Journal Article
FRONTIERS IN PHARMACOLOGY, ISSN 1663-9812, 09/2019, Volume 10
Mesangial proliferative glomerulonephritis (MPGN) is the most common type of chronic kidney disease in China, characterized by mesangial cell proliferation and...
APOPTOSIS | ACTIVATION | inflammatory response | INJURY | mesangial cells proliferation | PI3K/AKT/GSK-3 beta pathway | paeoniflorin | PI3K/AKT | GLYCOGEN-SYNTHASE KINASE-3-BETA | BREAST-CANCER | mesangial proliferative glomerulonephritis | NEPHRITIS | PHARMACOLOGY & PHARMACY | ACCUMULATION | UP-REGULATION | EXPRESSION | PI3K/AKT/GSK-3β pathway
APOPTOSIS | ACTIVATION | inflammatory response | INJURY | mesangial cells proliferation | PI3K/AKT/GSK-3 beta pathway | paeoniflorin | PI3K/AKT | GLYCOGEN-SYNTHASE KINASE-3-BETA | BREAST-CANCER | mesangial proliferative glomerulonephritis | NEPHRITIS | PHARMACOLOGY & PHARMACY | ACCUMULATION | UP-REGULATION | EXPRESSION | PI3K/AKT/GSK-3β pathway
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 12/2017, Volume 96, p. 137
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.biopha.2017.09.105...
Urea | Anthracyclines | Albumin | Triglycerides | Nephrotic syndrome
Urea | Anthracyclines | Albumin | Triglycerides | Nephrotic syndrome
Journal Article
Parasites and Vectors, ISSN 1756-3305, 12/2015, Volume 8, Issue 1, p. 634
Background: Plasmodium falciparum malaria is a significant public health problem in Comoros, and artemisinin combination therapy (ACT) remains the first choice...
K13-propeller | Artemisinin resistance | Plasmodium falciparum | Comoros | Polymorphism | PROPELLER GENE | SUB-SAHARAN AFRICA | PYRIMETHAMINE | AMODIAQUINE | IN-VIVO EFFICACY | CHLOROQUINE | TROPICAL MEDICINE | CHILDREN | MALARIA | MUTATIONS | ARTESUNATE | PARASITOLOGY | Haplotypes | Malaria, Falciparum - drug therapy | Gene Frequency | Humans | Antimalarials - therapeutic use | Genetic Markers | Plasmodium falciparum - drug effects | Sequence Analysis, DNA | Antimalarials - pharmacology | Malaria, Falciparum - parasitology | Artemisinins - pharmacology | Artemisinins - therapeutic use | Plasmodium falciparum - genetics | Plasmodium falciparum - isolation & purification | Comoros - epidemiology | Malaria, Falciparum - epidemiology | Polymerase Chain Reaction | Polymorphism, Single Nucleotide | Drug Resistance | Plant products | Usage | Genetic aspects | Virulence (Microbiology) | Drug resistance | Health aspects | Genetic polymorphisms
K13-propeller | Artemisinin resistance | Plasmodium falciparum | Comoros | Polymorphism | PROPELLER GENE | SUB-SAHARAN AFRICA | PYRIMETHAMINE | AMODIAQUINE | IN-VIVO EFFICACY | CHLOROQUINE | TROPICAL MEDICINE | CHILDREN | MALARIA | MUTATIONS | ARTESUNATE | PARASITOLOGY | Haplotypes | Malaria, Falciparum - drug therapy | Gene Frequency | Humans | Antimalarials - therapeutic use | Genetic Markers | Plasmodium falciparum - drug effects | Sequence Analysis, DNA | Antimalarials - pharmacology | Malaria, Falciparum - parasitology | Artemisinins - pharmacology | Artemisinins - therapeutic use | Plasmodium falciparum - genetics | Plasmodium falciparum - isolation & purification | Comoros - epidemiology | Malaria, Falciparum - epidemiology | Polymerase Chain Reaction | Polymorphism, Single Nucleotide | Drug Resistance | Plant products | Usage | Genetic aspects | Virulence (Microbiology) | Drug resistance | Health aspects | Genetic polymorphisms
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 05/2018, Volume 101, p. 635
Zhen-wu-tang (ZWT) has been widely applied in chronic kidney diseases. However, the mechanism of ZWT remains unclear. Peroxisome proliferator-activated...
Urea | Chronic kidney failure | Carbon tetrachloride | Low density lipoproteins | Albumin | Triglycerides | Uric acid | Immunoglobulin A | Mitogens
Urea | Chronic kidney failure | Carbon tetrachloride | Low density lipoproteins | Albumin | Triglycerides | Uric acid | Immunoglobulin A | Mitogens
Journal Article
International Immunopharmacology, ISSN 1567-5769, 04/2016, Volume 33, p. 33
Zhen-wu-tang (ZWT), a traditional Chinese compound formula recorded in the Treatise on Febrile Diseases, has significant inhibitory effects on inflammatory...
Glomerulonephritis | Albumin | Superoxide
Glomerulonephritis | Albumin | Superoxide
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 12/2017, Volume 96, pp. 137 - 147
Paeoniflorin (PF), an effective composition that is extracted from Alba, plays a role in protecting against various kidney diseases. However, the mechanism of...
Podocyte | Paeoniflorin | Angiopointin-like 4 | Peroxisome proliferator-activated receptor gamma | Nephrotic syndrome | KIDNEY-DISEASE | MEDICINE, RESEARCH & EXPERIMENTAL | RAT | RENAL-FUNCTION | FATTY-ACIDS | NEPHROPATHY | PATHOGENESIS | PODOCYTE INJURY | IMAGE-ANALYSIS | SYNAPTOPODIN | PHARMACOLOGY & PHARMACY | GAMMA AGONIST
Podocyte | Paeoniflorin | Angiopointin-like 4 | Peroxisome proliferator-activated receptor gamma | Nephrotic syndrome | KIDNEY-DISEASE | MEDICINE, RESEARCH & EXPERIMENTAL | RAT | RENAL-FUNCTION | FATTY-ACIDS | NEPHROPATHY | PATHOGENESIS | PODOCYTE INJURY | IMAGE-ANALYSIS | SYNAPTOPODIN | PHARMACOLOGY & PHARMACY | GAMMA AGONIST
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 05/2018, Volume 101, pp. 635 - 647
Zhen-wu-tang (ZWT) has been widely applied in chronic kidney diseases. However, the mechanism of ZWT remains unclear. Peroxisome proliferator-activated...
Zhen-wu-tang | Nuclear factor-kappaB | IgA nephropathy | Podocyte injury | Proliferator-activated receptors-γ | MEDICINE, RESEARCH & EXPERIMENTAL | DIURETIC ACTIVITY | OXIDATIVE STRESS | QUALITY-CONTROL | PORIA-COCOS | Proliferator-activated receptors-gamma | METABOLOMICS | SURFACE-LAYER | INFLAMMATION | RENAL-DISEASES | TRADITIONAL CHINESE MEDICINE | PHARMACOLOGY & PHARMACY | CHRONIC KIDNEY-DISEASE
Zhen-wu-tang | Nuclear factor-kappaB | IgA nephropathy | Podocyte injury | Proliferator-activated receptors-γ | MEDICINE, RESEARCH & EXPERIMENTAL | DIURETIC ACTIVITY | OXIDATIVE STRESS | QUALITY-CONTROL | PORIA-COCOS | Proliferator-activated receptors-gamma | METABOLOMICS | SURFACE-LAYER | INFLAMMATION | RENAL-DISEASES | TRADITIONAL CHINESE MEDICINE | PHARMACOLOGY & PHARMACY | CHRONIC KIDNEY-DISEASE
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 11/2018, Volume 67, Issue 11, pp. 1670 - 1676
Does adding low-dose primaquine to mass drug administration of artemisinin-based combination therapy improve malaria control? On a highly endemic African...
malaria control | Comoros Islands | Plasmodium falciparum | PfK13 Kelch-propeller gene | artemisinin-based combination therapy | INFECTIOUS DISEASES | ARTEMETHER-LUMEFANTRINE | MICROBIOLOGY | IMMUNOLOGY | PLASMODIUM-FALCIPARUM MALARIA | DOSE PRIMAQUINE | FAILURE | CAMBODIA | CHILDREN | TRANSMISSION | DIHYDROARTEMISININ-PIPERAQUINE | DOUBLE-BLIND | and Commentaries
malaria control | Comoros Islands | Plasmodium falciparum | PfK13 Kelch-propeller gene | artemisinin-based combination therapy | INFECTIOUS DISEASES | ARTEMETHER-LUMEFANTRINE | MICROBIOLOGY | IMMUNOLOGY | PLASMODIUM-FALCIPARUM MALARIA | DOSE PRIMAQUINE | FAILURE | CAMBODIA | CHILDREN | TRANSMISSION | DIHYDROARTEMISININ-PIPERAQUINE | DOUBLE-BLIND | and Commentaries
Journal Article
Phytomedicine, ISSN 0944-7113, 06/2019, Volume 59, p. 152913
Zhen-wu-tang (ZWT), a traditional herbal formula, has been widely used for the treatment of kidney diseases in clinics, but the underlying molecular mechanisms...
Zhen-wu-tang | Membranous nephropathy | Nuclear factor-κB | NLRP3 inflammasome | Nuclear factor-kappa B | KIDNEY-DISEASE | ACTIVATION | CHEMISTRY, MEDICINAL | PORIA-COCOS | PLANT SCIENCES | PODOCYTE INJURY | PHYTOCHEMISTRY | INTEGRATIVE & COMPLEMENTARY MEDICINE | EPIDERMIS | IGA NEPHROPATHY | PHARMACOLOGY & PHARMACY | RENAL INJURY | EXPRESSION | BOVINE SERUM-ALBUMIN
Zhen-wu-tang | Membranous nephropathy | Nuclear factor-κB | NLRP3 inflammasome | Nuclear factor-kappa B | KIDNEY-DISEASE | ACTIVATION | CHEMISTRY, MEDICINAL | PORIA-COCOS | PLANT SCIENCES | PODOCYTE INJURY | PHYTOCHEMISTRY | INTEGRATIVE & COMPLEMENTARY MEDICINE | EPIDERMIS | IGA NEPHROPATHY | PHARMACOLOGY & PHARMACY | RENAL INJURY | EXPRESSION | BOVINE SERUM-ALBUMIN
Journal Article
发展, ISSN 1004-8863, 2011, Issue 1, pp. 97 - 98
Journal Article
Intervirology, ISSN 0300-5526, 07/2017, Volume 59, Issue 5-6, pp. 267 - 274
Objective: This study is aimed at examining the effects of Maxing Shigan Tang (MST) treatment on H1N1-associated acute lung injury (ALI) and exploring the...
Original Paper | Maxing Shigan Tang | H1N1 influenza A virus-associated acute lung injury | Mice | VIROLOGY | ANGIOPOIETIN-LIKE 4 | AGENTS | ANGPTL4 | MEDICINE | PHARMACOVIGILANCE
Original Paper | Maxing Shigan Tang | H1N1 influenza A virus-associated acute lung injury | Mice | VIROLOGY | ANGIOPOIETIN-LIKE 4 | AGENTS | ANGPTL4 | MEDICINE | PHARMACOVIGILANCE
Journal Article