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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2019, Volume 116, Issue 12, pp. 5362 - 5369
Lipid nanovesicles are widely present as transport vehicles in living organisms and can serve as efficient drug delivery vectors. It is known that the size and... 
Liposome | Phase transition temperature | Diffusion | Lipid nanovesicle | Biological hydrogels | TRANSLOCATION | diffusion | DRUG-DELIVERY | MULTIDISCIPLINARY SCIENCES | lipid nanovesicle | GASTROINTESTINAL MUCUS | BENDING RIGIDITY | MECHANICAL-PROPERTIES | liposome | phase transition temperature | NANOPARTICLES | PHASE | EXTRACELLULAR VESICLES | biological hydrogels | FORMULATIONS | ORAL DELIVERY | Diabetes Mellitus, Experimental - drug therapy | Temperature | Epithelium - metabolism | Nanoparticles - chemistry | Rats | Insulin - administration & dosage | Male | Diffusion - drug effects | Rats, Sprague-Dawley | Drug Carriers - chemistry | Lipids - chemistry | Liposomes - chemistry | Animals | Insulin - chemistry | Phase Transition - drug effects | Hydrogels - administration & dosage | Biological Transport - drug effects | Drug Delivery Systems - methods | Hydrogels - chemistry | Drug delivery systems | Hydrogels | Molecular dynamics | Lipids | Mucus | Drug delivery | Rigidity | Exosomes | Drug development | Phase transitions | Ambient temperature | Temperature effects | Surface charge | Transition temperature | Phase transformations | Computer simulation | Deformation mechanisms | Body temperature | Diabetes mellitus | Epithelium | Insulin | Transition temperatures | Microscopy | Liposomes | Transport vehicles | Endosomes | Phase transition | Physical Sciences | PNAS Plus
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 470 - 10
Integrative analysis of multi-omics layers at single cell level is critical for accurate dissection of cell-to-cell variation within certain cell populations.... 
NUCLEOTIDE | CHROMATIN ACCESSIBILITY | NUMBER | GENOME-WIDE DETECTION | MULTIDISCIPLINARY SCIENCES | EMBRYOS | Heterogeneity | Deconvolution | Transcription factors | Chromatin | Populations | Accessibility | Regulatory sequences | Gene expression | Embryos | Dissection
Journal Article
Drug Discovery Today, ISSN 1359-6446, 05/2016, Volume 21, Issue 5, pp. 856 - 863
Journal Article
Journal Article
Journal Article
Biomaterials, ISSN 0142-9612, 01/2018, Volume 151, pp. 13 - 23
Oral absorption of protein/peptide-loaded nanoparticles is often limited by multiple barriers of the intestinal epithelium. In addition to mucus translocation... 
Functional nanoparticles | Bile acid pathway | Intestinal epithelium | Insulin | Oral delivery | Endolysosomal escape | MATERIALS SCIENCE, BIOMATERIALS | DRUG-DELIVERY | ENGINEERING, BIOMEDICAL | BIODEGRADABLE NANOPARTICLES | SIRNA DELIVERY | CELLULAR UPTAKE | DEOXYCHOLIC-ACID | IN-VITRO | TRANSPORT | POLYMERIC NANOPARTICLES | MEDIATED ENDOCYTOSIS | ABSORPTION | Diabetes Mellitus, Experimental - drug therapy | Intestinal Mucosa - metabolism | Membrane Glycoproteins - metabolism | Nanoparticles - chemistry | Humans | Membrane Glycoproteins - chemistry | Deoxycholic Acid - chemistry | Biological Availability | Male | Drug Carriers - chemistry | Organic Anion Transporters, Sodium-Dependent - chemistry | Surface Properties | Carrier Proteins - chemistry | Mucus - metabolism | Caco-2 Cells | Insulin - pharmacology | Drug Trafficking | Administration, Oral | Insulin - administration & dosage | Permeability | Symporters - chemistry | Bile Acids and Salts | Rats, Sprague-Dawley | Symporters - metabolism | Particle Size | Animals | Carrier Proteins - metabolism | Chitosan - chemistry | Cardiovascular System - metabolism | Deoxycholic Acid - metabolism | Drug Liberation | Insulin - adverse effects | Insulin - pharmacokinetics | Organic Anion Transporters, Sodium-Dependent - metabolism | Nanoparticles | Analysis | Epithelium | Diabetes therapy | Protein binding | Deoxycholic acid
Journal Article
Current Drug Metabolism, ISSN 1389-2002, 08/2015, Volume 16, Issue 3, pp. 200 - 210
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 09/2015, Volume 213, pp. e25 - e26
Journal Article
Colloids and Surfaces B: Biointerfaces, ISSN 0927-7765, 05/2016, Volume 141, pp. 301 - 310
Journal Article
Asian Journal of Pharmaceutical Sciences, ISSN 1818-0876, 07/2018, Volume 13, Issue 4, pp. 326 - 335
Self-nanoemulsifying systems (SNEs) have excellent ability to improve the solubility of poorly water-soluble drugs (PWSD). However, SNEs are likely to be... 
Oral absorption | Enzymatic degradation | Pluronic® F127 | Mucus penetration | Self-nanoemulsifying system (SNEs) | DRUG | MULTIPLE-PARTICLE TRACKING | Pluronic (R) F127 | ABSORPTION BARRIER | BIOAVAILABILITY | MEDIUM-CHAIN | NANOPARTICLES | IN-VITRO | LIPID-BASED FORMULATIONS | CYCLOSPORINE-A | DIFFUSION BARRIER | PHARMACOLOGY & PHARMACY
Journal Article
Current Drug Metabolism, ISSN 1389-2002, 03/2015, Volume 16, Issue 3, pp. 200 - 210
The application of lipid-based drug delivery systems on the industrial scale has successfully demonstrated their therapeutic and manufacturing advantages.... 
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 06/2013, Volume 449, Issue 1-2, p. 1
Journal Article
Biomaterials, ISSN 0142-9612, 2014, Volume 37, pp. 320 - 332
Journal Article