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Medicine, ISSN 0025-7974, 09/2018, Volume 97, Issue 39, p. e11816
Background: Transient elastography (TE) has been validated as an effective noninvasive tool for the assessment of liver fibrosis. The XL probe is a new probe... 
MANAGEMENT | CHRONIC HEPATITIS-C | BIOPSY | transient elastography | STIFFNESS MEASUREMENT | obese | MEDICINE, GENERAL & INTERNAL | liver fibrosis | OBESE-PATIENTS | FIBROSCAN(R) | DISEASE | INFECTION | FIBROTEST | XL probe | NONINVASIVE ASSESSMENT | Measurement | Evaluation | Diagnostic equipment (Medical) | Fibrosis | Elasticity | Diagnosis | Liver cirrhosis | Health aspects
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, p. e60516
Journal Article
Aging, ISSN 1945-4589, 2017, Volume 9, Issue 3, pp. 1 - 9
Senescent cells accumulate with aging and at sites of pathology in multiple chronic diseases. Senolytics are drugs that selectively promote apoptosis of... 
inhibitors | Flavonoids | BCL-X | Aging | Preadipocytes | Adipose-derived stem cells | Senolytics | Apoptosis | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2017, Volume 114, Issue 45, pp. E9559 - E9568
Alterations in the activity/levels of the extralarge G protein alpha-sub-unit (XL alpha s) are implicated in various human disorders, such as perinatal growth... 
GNAS | Endocytosis | Transferrin | Stimulatory G protein | Heterotrimeric G proteins | ACTIVATION | DOMAIN | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | transferrin | DOWN-REGULATION | VARIANT | stimulatory G protein | heterotrimeric G proteins | VASOPRESSIN TYPE-2 RECEPTOR | endocytosis | PARATHYROID-HORMONE | SORTING NEXIN-9 | MUTATIONS | Biological Sciences | PNAS Plus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2018, Volume 115, Issue 12, pp. E2762 - E2771
Journal Article
Cell death and differentiation, ISSN 1350-9047, 07/2019
Mitochondria are highly dynamic organelles and respond to stress by changing their fission-fusion cycle, undergoing mitophagy, or releasing apoptotic proteins... 
Journal Article
Steroids, ISSN 0039-128X, 10/2019, Volume 150, p. 108381
2-Methoxyestradiol is an endogenous nonpolar metabolite of 17β-estradiol with a strong antitubulin activity. Earlier we showed that 2-methoxyestradiol... 
2-Methoxyestradiol | Bcl-2 | CDK1 | Bcl-XL | Prometaphase arrest | Cyclin B1
Journal Article
Hepatology (Baltimore, Md.), ISSN 0270-9139, 1/2018, Volume 67, Issue 1, pp. 247 - 259
Cholangiocyte senescence has been linked to primary sclerosing cholangitis (PSC). Persistent secretion of growth factors by senescent cholangiocytes leads to... 
Apoptotic Priming | Bcl-xL | Senolytics | Primary Sclerosing Cholangitis | BH3 Mimetic
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2018, Volume 115, Issue 12, p. E2762
The accumulation of misfolded proteins in the endoplasmic reticulum (ER) causes ER stress and triggers the unfolded protein response (UPR). Failure to resolve... 
Stresses | Bcl-2 protein | Biosynthesis | Stress | Membrane proteins | Proteins | Bcl-x protein | Protein folding | Cell death | Stress response | Endoplasmic reticulum | Ubiquitin-protein ligase | Apoptosis
Journal Article
Cell Death and Disease, ISSN 2041-4889, 05/2019, Volume 10, Issue 5, pp. 342 - 14
Malignant melanoma is one of the most difficult cancers to treat due to its resistance to chemotherapy. Despite recent successes with BRAF inhibitors and... 
PLATFORM | APOPTOSIS | POTENT | MICROENVIRONMENT | BH3-MIMETIC ABT-737 | AGENTS | MODEL | INHIBITOR | CANCER | NOXA | CELL BIOLOGY | Bortezomib | Cell survival | Bax protein | Bcl-2 protein | Melanoma | Drug resistance | Mcl-1 protein | Immunosuppressive agents | Proteasome inhibitors | Skin cancer | Proteins | Chemotherapy | Immune checkpoint | Bcl-x protein | Clonal deletion | Cell lines | Apoptosis | Cancer
Journal Article
Cancer Letters, ISSN 0304-3835, 2014, Volume 352, Issue 2, pp. 203 - 213
Journal Article