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Clinical Cancer Research, ISSN 1078-0432, 08/2017, Volume 23, Issue 15, pp. 4335 - 4346
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 3935 - 3935
Journal Article
Neoplasia, ISSN 1476-5586, 2013, Volume 15, Issue 10, pp. 1161 - IN24
Journal Article
International Journal of Cancer, ISSN 0020-7136, 09/2019, Volume 145, Issue 5, pp. 1346 - 1357
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 4933 - 4933
Gastric cancer is the 3rd most common cause of cancer-related mortality worldwide, thus new treatment options are urgently needed. In gastric cancer,... 
Journal Article
International Journal of Cancer, ISSN 0020-7136, 01/2017, Volume 140, Issue 2, pp. 449 - 459
Journal Article
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 05/2017, Volume 16, Issue 5, pp. 893 - 904
C4.4A (LYPD3) has been identified as a cancer-and metastasisassociated internalizing cell surface protein that is expressed in non-small cell lung cancer... 
C4.4A | ONCOLOGY | MARKER | MOLECULE | CLONING | POOR-PROGNOSIS | UROKINASE RECEPTOR | HOMOLOG | IDENTIFICATION | EXPRESSION | CARCINOMA | Cisplatin - immunology | Humans | Cell Adhesion Molecules - antagonists & inhibitors | Aminobenzoates - immunology | Cell Adhesion Molecules - immunology | Vinblastine - administration & dosage | Immunoconjugates - administration & dosage | Cisplatin - administration & dosage | Immunoconjugates - immunology | Vinblastine - analogs & derivatives | Paclitaxel - immunology | Vinblastine - immunology | GPI-Linked Proteins - antagonists & inhibitors | Paclitaxel - administration & dosage | Oligopeptides - chemistry | Antibodies, Monoclonal - immunology | GPI-Linked Proteins - immunology | Carcinoma, Non-Small-Cell Lung - genetics | Oligopeptides - immunology | Immunoconjugates - chemistry | Carcinoma, Non-Small-Cell Lung - immunology | Xenograft Model Antitumor Assays | Animals | Aminobenzoates - chemistry | Antibodies, Monoclonal - administration & dosage | Cell Line, Tumor | Mice | Carcinoma, Non-Small-Cell Lung - drug therapy | Cell proliferation | Squamous cell carcinoma | Effectiveness | Lung cancer | Keratinocytes | Non-small cell lung carcinoma | Cytotoxicity | Tissues | Cell surface | Cisplatin | Endothelial cells | Metastases | Esophagus | Anticancer properties | Lungs | Cell lines | Paclitaxel | Xenografts | Monoclonal antibodies | Antitumor activity | Skin | Vinorelbine | Cancer
Journal Article
Journal Article
ChemMedChem, ISSN 1860-7179, 11/2017, Volume 12, Issue 21, pp. 1776 - 1793
Journal Article
Cancer Medicine, ISSN 2045-7634, 10/2013, Volume 2, Issue 5, pp. 611 - 624
The activation of the transcription factor hypoxia‐inducible factor‐1 (HIF‐1) plays an essential role in tumor development, tumor progression, and resistance... 
hypoxia | Antitumor activity | hypoxia‐inducible factor‐1 | mitochondrial complex 1 | ONCOLOGY | hypoxia-inducible factor-1 | Lung Neoplasms - drug therapy | Oxadiazoles - administration & dosage | RNA, Small Interfering - genetics | Pyrazoles - therapeutic use | Carbonic Anhydrases - biosynthesis | Carbonic Anhydrases - genetics | Genes, Neoplasm | Humans | Lung Neoplasms - metabolism | Antigens, Neoplasm - biosynthesis | Molecular Sequence Data | Drug Discovery - methods | Lung Neoplasms - pathology | Electron Transport Complex I - metabolism | Hypoxia-Inducible Factor 1 - genetics | Dose-Response Relationship, Drug | Oxadiazoles - pharmacology | Pyrazoles - blood | Female | Gene Expression Regulation, Neoplastic - drug effects | Tumor Cells, Cultured | Genes, Reporter | Molecular Targeted Therapy - methods | Carbonic Anhydrase IX | Hypoxia-Inducible Factor 1 - biosynthesis | Pyrazoles - pharmacology | Lung Neoplasms - genetics | Antigens, Neoplasm - genetics | Electron Transport Complex I - antagonists & inhibitors | Hypoxia-Inducible Factor-Proline Dioxygenases - genetics | Von Hippel-Lindau Tumor Suppressor Protein - physiology | Xenograft Model Antitumor Assays - methods | Oxadiazoles - therapeutic use | Pyrazoles - administration & dosage | Animals | Tumor Burden - drug effects | Hypoxia-Inducible Factor-Proline Dioxygenases - metabolism | Mice, Nude | Small Molecule Libraries | Oxadiazoles - blood | Cell Proliferation - drug effects | Mice | Cell Hypoxia - genetics | Tumors | Cell proliferation | Cell culture | Lung cancer | Cytotoxicity | Kinases | Experiments | Cobalt | Deferoxamine | Proteins | Electron transport chain | Mitochondria | Cobalt chloride | Transcription activation | Xenografts | Prolyl hydroxylase | Vascular endothelial growth factor | Library collections | NADH-ubiquinone oxidoreductase | Hydroxylase | Non-small cell lung carcinoma | Radiation therapy | Tumor cell lines | Gene expression | Medical prognosis | Cell lines | Hypoxia | VHL protein | Cancer Biology
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 10/2012, Volume 11, Issue 10, pp. 2265 - 2273
Deregulated activity of cyclin-dependent kinases (CDK) results in loss of cell-cycle checkpoint function and increased expression of antiapoptotic proteins,... 
BREAST-CANCER | DOSE-ESCALATION | LUNG-CANCER | TERMINAL DOMAIN | SOLID TUMORS | ONCOLOGY | TUMOR-GROWTH INHIBITOR | DRUG DEVELOPMENT | CELL-CYCLE | ZK 304709 | CDK | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Cyclin-Dependent Kinases - metabolism | Antineoplastic Combined Chemotherapy Protocols - chemistry | Humans | Sulfoxides - pharmacokinetics | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Antineoplastic Agents - administration & dosage | Pyrimidines - chemistry | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Sulfoxides - administration & dosage | Protein Kinase Inhibitors - chemistry | Female | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Cyclin-Dependent Kinases - antagonists & inhibitors | Phosphorylation - drug effects | Protein Kinase Inhibitors - pharmacokinetics | Sulfoxides - pharmacology | Administration, Oral | Pyrimidines - administration & dosage | Retinoblastoma Protein - metabolism | Etoposide - pharmacology | Rats | Treatment Outcome | Cisplatin - pharmacology | Pyrimidines - pharmacology | Antineoplastic Agents - chemistry | Xenograft Model Antitumor Assays | Protein Kinase Inhibitors - administration & dosage | Sulfoxides - chemistry | Animals | Mice, Nude | Pyrimidines - pharmacokinetics | Mice | Protein Kinase Inhibitors - pharmacology | Cell Cycle - drug effects
Journal Article
Journal Article