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Nature Genetics, ISSN 1061-4036, 05/2017, Volume 49, Issue 5, pp. 742 - 752
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1 - 11
The recent rapid spread of single cell RNA sequencing (scRNA-seq) methods has created a large variety of experimental and computational pipelines for which... 
Computer simulation | Pipelines | Computer applications | Mapping | Libraries | Ribonucleic acid--RNA | Impact analysis | Gene sequencing
Journal Article
Scientific Reports, ISSN 2045-2322, 05/2016, Volume 6, Issue 1, p. 25533
Currently, quantitative RNA-seq methods are pushed to work with increasingly small starting amounts of RNA that require amplification. However, it is unclear... 
TRANSCRIPTOMICS | CONSORTIUM | CELLS | SINGLE | SIGNAL SATURATION | GENOMES | BIAS | MULTIDISCIPLINARY SCIENCES | MICROARRAYS | LOW-INPUT | PROGRAM | Polymerase chain reaction | Data processing | Gene expression | Ribonucleic acid--RNA | Computer applications
Journal Article
Journal Article
Cancer Cell, ISSN 1535-6108, 12/2016, Volume 30, Issue 6, pp. 849 - 862
Tumor relapse is associated with dismal prognosis, but responsible biological principles remain incompletely understood. To isolate and characterize... 
RNA single-cell sequencing | minimal residual disease (MRD) | acute lymphoblastic leukemia | patient-derived xenograft (PDX) cells | Cancer stem cells | primary patients' ALL MRD cells | dormant tumor cells | treatment resistance | INITIATING CELLS | STEM-CELLS | ONCOLOGY | MYELOID-LEUKEMIA | PROPAGATING CELLS | MINIMAL RESIDUAL DISEASE | CANCER | CHILDHOOD | CHEMOTHERAPY | DISCOVERY | XENOGRAFTS | CELL BIOLOGY | Neoplasm, Residual - pathology | Neoplasm Transplantation | Cell Proliferation | Prognosis | Humans | Gene Expression Regulation, Neoplastic | Drug Resistance, Neoplasm | Neoplasm Recurrence, Local - pathology | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Neoplastic Stem Cells - pathology | Adult | Tumor Cells, Cultured | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Single-Cell Analysis | Child | Antineoplastic Combined Chemotherapy Protocols - metabolism | Gene Expression Profiling - methods | Neoplasm, Residual - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Sequence Analysis, RNA - methods | Disease-Free Survival | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Neoplasm Recurrence, Local - genetics | Mice | Proto-Oncogene Proteins c-myc - genetics | Medical colleges | Genetic vectors | Genetically modified organisms | Genetic engineering | Research institutes | Acute lymphocytic leukemia | Health aspects | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2937 - 8
Single-cell RNA sequencing (scRNA-seq) has emerged as a central genome-wide method to characterize cellular identities and processes. Consequently, improving... 
MULTIDISCIPLINARY SCIENCES | TECHNOLOGIES | Sequence Analysis, RNA - methods | Software | High-Throughput Nucleotide Sequencing - methods | Single-Cell Analysis | Base Sequence | RNA - genetics | Polymerase | Sensitivity | Polyethylene | Polyethylene glycol | Sensitivity enhancement | Genomes | Ribonucleic acid--RNA | Chemical synthesis | Molecular chains | Gene sequencing
Journal Article
Bioinformatics (Oxford, England), ISSN 1367-4803, 11/2017, Volume 33, Issue 21, pp. 3486 - 3488
Power analysis is essential to optimize the design of RNA-seq experiments and to assess and compare the power to detect differentially expressed genes in... 
DESIGN | MODEL | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | Sequence Analysis, RNA - methods | Gene Expression Profiling - methods | Software | Single-Cell Analysis
Journal Article
Nature, ISSN 0028-0836, 02/2018, Volume 554, Issue 7690, pp. 62 - 68
Journal Article
JOURNAL OF CELL SCIENCE, ISSN 0021-9533, 05/2018, Volume 131, Issue 10, pp. jcs212886 - jcs212886
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2019, Volume 9, Issue 1, pp. 9731 - 17
Actin binding compounds are widely used tools in cell biology. We compare the biological and biochemical effects of miuraenamide A and jasplakinolide, a... 
F-ACTIN | NATURAL-PRODUCT | MOLECULAR-DYNAMICS | BENZENE DIMER | CYTOSKELETON | AMBER | MULTIDISCIPLINARY SCIENCES | MECHANISMS | SIMULATIONS | NUCLEATION | PROTEINS | Jasplakinolide | Transcription | Actin | Cofilin | Cytoskeleton | Gelsolin | Gene expression | Monomers | Endothelial cells | Binding sites
Journal Article
Scientific reports, 05/2016, Volume 6, p. 25533
Currently, quantitative RNA-seq methods are pushed to work with increasingly small starting amounts of RNA that require amplification. However, it is unclear... 
Sequence Analysis, RNA - methods | Gene Library | HCT116 Cells | Humans | Gene Expression Regulation | Databases, Genetic | Gene Expression Profiling - methods
Journal Article