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by Roadmap Epigenomics Consortium, Epigenomics Consortium and Kundaje, Anshul and Meuleman, Wouter and Ernst, Jason and Bilenky, Misha and Yen, Angela and Heravi-Moussavi, Alireza and Kheradpour, Pouya and Zhang, Zhizhuo and Wang, Jianrong and Ziller, Michael J and Amin, Viren and Whitaker, John W and Schultz, Matthew D and Ward, Lucas D and Sarkar, Abhishek and Quon, Gerald and Sandstrom, Richard S and Eaton, Matthew L and Wu, Yi-Chieh and Pfenning, Andreas R and Wang, Xinchen and Claussnitzer, Melina and Liu, Yaping and Coarfa, Cristian and Harris, R. Alan and Shoresh, Noam and Epstein, Charles B and Gjoneska, Elizabeta and Leung, Danny and Xie, Wei and Hawkins, R. David and Lister, Ryan and Hong, Chibo and Gascard, Philippe and Mungall, Andrew J and Moore, Richard and Chuah, Eric and Tam, Angela and Canfield, Theresa K and Hansen, R. Scott and Kaul, Rajinder and Sabo, Peter J and Bansal, Mukul S and Carles, Annaick and Dixon, Jesse R and Farh, Kai-How and Feizi, Soheil and Karlic, Rosa and Kim, Ah-Ram and Kulkarni, Ashwinikumar and Li, Daofeng and Lowdon, Rebecca and Elliott, Ginell and Mercer, Tim R and Neph, Shane J and Onuchic, Vitor and Polak, Paz and Rajagopal, Nisha and Ray, Pradipta and Sallari, Richard C and Siebenthall, Kyle T and Sinnott-Armstrong, Nicholas A and Stevens, Michael and Thurman, Robert E and Wu, Jie and Zhang, Bo and Zhou, Xin and Beaudet, Arthur E and Boyer, Laurie A and De Jager, Philip L and Farnham, Peggy J and Fisher, Susan J and Haussler, David and Jones, Steven J. M and Li, Wei and Marra, Marco A and McManus, Michael T and Sunyaev, Shamil and Thomson, James A and Tlsty, Thea D and Tsai, Li-Huei and Wang, Wei and Waterland, Robert A and Zhang, Michael Q and Chadwick, Lisa H and Bernstein, Bradley E and Costello, Joseph F and Ecker, Joseph R and Hirst, Martin and Meissner, Alexander and Milosavljevic, Aleksandar and Ren, Bing and Stamatoyannopoulos, John A and Wang, Ting and Kellis, Manolis and Roadmap Epigenomics Consortium
Nature, ISSN 0028-0836, 02/2015, Volume 518, Issue 7539, pp. 317 - 329
Journal Article
Cell Reports, ISSN 2211-1247, 04/2019, Volume 27, Issue 3, pp. 708 - 718.e10
Studies in vertebrates have outlined conserved molecular control of definitive endoderm (END) development. However, recent work also shows that key molecular... 
perturbation screen | endoderm | stem cell differentiation | pluripotent stem cells | CRISPRi | dCas9-KRAB | human development | hepatic endoderm | chromatin accessibility | single-cell RNA-seq | PLURIPOTENT STEM-CELLS | PRIMITIVE STREAK | MAINTENANCE | TRANSCRIPTION | MOUSE | FOXH1 | DEFINITIVE ENDODERM | GENE-EXPRESSION | DIFFERENTIATION | FOXA2 | CELL BIOLOGY
Journal Article
Nature, ISSN 0028-0836, 2/2015, Volume 518, Issue 7539, pp. 344 - 349
Pluripotent stem cells provide a powerful system to dissect the underlying molecular dynamics that regulate cell fate changes during mammalian development.... 
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