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Journal of Molecular Evolution, ISSN 0022-2844, 2011, Volume 73, Issue 3, pp. 209 - 220
The TOR kinase is a major regulator of growth in eukaryotes. Many components of the TOR pathway are implicated in cancer and metabolic diseases in humans.... 
Life Sciences | Microbiology | Rheb | TOR | Pathway evolution | TSC1-2 complex | Evolutionary Biology | AGC kinases | Plant Sciences | Cell Biology | Animal Genetics and Genomics | Plant Genetics & Genomics | FISSION YEAST | PROTEIN-KINASE-B | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-GROWTH | SACCHAROMYCES-CEREVISIAE | TRANSLATIONAL CONTROL | EVOLUTIONARY BIOLOGY | CAENORHABDITIS-ELEGANS | TUMOR-SUPPRESSOR COMPLEX | GENETICS & HEREDITY | RIBOSOMAL S6 KINASE | TUBEROUS SCLEROSIS | SCHIZOSACCHAROMYCES-POMBE | Fungal Proteins - chemistry | Gene Duplication | Amino Acid Sequence | Transcription Factors - chemistry | Humans | Gene Expression Regulation | Multiprotein Complexes - genetics | Signal Transduction - genetics | Fungal Proteins - genetics | Phylogeny | Transcription Factors - genetics | Gene Regulatory Networks | Protozoan Proteins - genetics | Sequence Homology, Amino Acid | Animals | TOR Serine-Threonine Kinases - genetics | TOR Serine-Threonine Kinases - chemistry | Conserved Sequence | Protozoan Proteins - chemistry | Models, Genetic | Evolution, Molecular | Oncology, Experimental | Analysis | Evolution | Universities and colleges | Research | Phosphotransferases | Cancer | Genetics | Eukaryotes | Evolutionary biology | Kinases | Molecular biology | Signal transduction | protein-serine kinase | molecular evolution | Metabolic disorders
Journal Article
Neuron, ISSN 0896-6273, 09/2013, Volume 79, Issue 6, pp. 1169 - 1182
The gene is located in a chromosomal region linked to various neurological disorders, including intellectual disability, autism, and schizophrenia. CYFIP1... 
MAMMALIAN TARGET | LOCAL PROTEIN-SYNTHESIS | AUTISM | FMRP | MOUSE MODEL | FRAGILE-X-SYNDROME | MECHANISMS | RAC1 | SYNAPTIC PLASTICITY | NEUROSCIENCES | CRITICAL REGION | Humans | Male | Fragile X Mental Retardation Protein - metabolism | Green Fluorescent Proteins - genetics | RNA, Messenger - metabolism | Mental Disorders - genetics | Brain-Derived Neurotrophic Factor - pharmacology | Neurons - ultrastructure | Time Factors | Chromatography, Liquid | Nerve Tissue Proteins - ultrastructure | Enzyme Inhibitors - pharmacology | Mice, Transgenic | Pyrimidines - pharmacology | Synaptosomes - ultrastructure | Analysis of Variance | Indole Alkaloids - pharmacology | Protein Biosynthesis - drug effects | Mice | Carbazoles - pharmacology | Adaptor Proteins, Signal Transducing - chemistry | Synaptosomes - drug effects | Meta-Analysis as Topic | Immunoprecipitation | Age Factors | Synaptosomes - metabolism | Cerebral Cortex - cytology | Microscopy, Immunoelectron | DNA-Binding Proteins - metabolism | Tandem Mass Spectrometry | Nerve Tissue Proteins - chemistry | Transfection | Dendritic Spines - drug effects | Protein Biosynthesis - genetics | Neurons - drug effects | Aminoquinolines - pharmacology | Green Fluorescent Proteins - metabolism | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Cells, Cultured | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Animals | Adaptor Proteins, Signal Transducing - genetics | Fragile X Mental Retardation Protein - ultrastructure | Dendritic Spines - genetics | Fragile X Mental Retardation Protein - genetics | Adaptor Proteins, Signal Transducing - metabolism | In Vitro Techniques | Dendritic Spines - ultrastructure | Luminescent Proteins - metabolism | Nervous system diseases | Neurosciences | Neurons | Oncology, Experimental | Genes | Polymerization | Schizophrenia | Protein biosynthesis | Research | Genetic translation | Messenger RNA | Actin | Cancer | Proteins | Brain-derived neurotrophic factor | Protein synthesis | Crystal structure
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2004, Volume 279, Issue 34, pp. 35127 - 35132
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, p. e81649
Journal Article
Journal Article