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Investigational New Drugs, ISSN 0167-6997, 2/2019, Volume 37, Issue 1, pp. 147 - 158
Journal Article
Journal Article
Biological Chemistry, ISSN 1431-6730, 09/2005, Volume 386, Issue 9, pp. 845 - 855
The epidermal growth factor receptor (EGFR) plays a key role in the regulation of important cellular processes under normal and pathophysiological conditions... 
ADAM | sphingosine kinase (SPHK) | breast cancer | shedding | cross-talk | HB-EGF | Shedding | Breast cancer | Sphingosine kinase (SPHK) | Cross-talk | CANCER-CELLS | GROWTH-FACTOR-RECEPTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLIFERATION | OVARIAN-CANCER | INVASION | LYSOPHOSPHATIDIC ACID | PLASMINOGEN-ACTIVATOR | PROTEIN-COUPLED RECEPTOR | KINASE ACTIVATION | ADAM17 Protein | Receptor, Epidermal Growth Factor - genetics | Phosphorylation | Receptors, G-Protein-Coupled - metabolism | Humans | Molecular Sequence Data | Receptors, G-Protein-Coupled - agonists | Receptor Cross-Talk - physiology | Cell Movement - physiology | Metalloproteases - metabolism | Breast Neoplasms - metabolism | Metalloproteases - antagonists & inhibitors | Receptor, Epidermal Growth Factor - metabolism | Transfection | Female | Membrane Proteins - metabolism | Tumor Cells, Cultured | Proto-Oncogene Proteins c-akt - metabolism | Receptor, Epidermal Growth Factor - physiology | Receptors, G-Protein-Coupled - physiology | Shc Signaling Adaptor Proteins | Amino Acid Sequence | ADAM Proteins - antagonists & inhibitors | Membrane Proteins - genetics | Phospholipids - pharmacology | Pregnancy | Cell Movement - drug effects | ADAM Proteins - metabolism | Animals | Breast Neoplasms - genetics | Src Homology 2 Domain-Containing, Transforming Protein 1 | Membrane Proteins - antagonists & inhibitors | Breast Neoplasms - pathology | Cell Line, Tumor | Signal Transduction - physiology | Mice | Enzyme Activation | ADAM Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | Mitogen-Activated Protein Kinases - metabolism | Genetic aspects | G proteins | Health aspects | Cell migration | Cancer cells
Journal Article
08/2015
The present application relates to the combined use of an antigen-binding protein that binds HB-EGF and an EGFR tyrosine kinase inhibitor in medical treatment. 
METALLURGY | PEPTIDES | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
02/2015
The present application relates to the combined use of an antigen-binding protein that binds HB-EGF and an EGFR tyrosine kinase inhibitor in medical treatment. 
HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
12/2014
The present application relates to the combined use of an antigen-binding protein that binds HB-EGF and an EGFR tyrosine kinase inhibitor in medical treatment. 
METALLURGY | PEPTIDES | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
Cancer research (Chicago, Ill.), ISSN 0008-5472, 04/2012, Volume 72, Issue 8 Supplement, pp. 2519 - 2519
Journal Article
08/2013
The present application relates to the combined use of an antigen-binding protein that binds HB-EGF and an EGFR tyrosine kinase inhibitor in medical treatment.... 
METALLURGY | PEPTIDES | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
Cancer research (Chicago, Ill.), ISSN 0008-5472, 04/2011, Volume 71, Issue 8 Supplement, pp. 3148 - 3148
Journal Article
10/2016
Στην παρούσα δημοσίευση παρουσιάζονται πρωτεΐνες δέσμευσης αντιγόνου, π.χ. ανθρώπινα και/ή μονόκλωνα αντισώματα, τα οποία έχουν συγγένεια για τον αυξητικό... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | METALLURGY | PEPTIDES | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
01/2016
Provided herein are antigen binding proteins, e.g., human and/or monoclonal antibodies that have affinity for heparin-binding epidermal growth factor-like... 
METALLURGY | PEPTIDES | ORGANIC CHEMISTRY | CHEMISTRY
Patent
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