Nephrology, Dialysis, Transplantation, ISSN 0931-0509, 04/2019, Volume 34, Issue 4, pp. 547 - 551
Journal Article
Transplantation, ISSN 0041-1337, 08/2016, Volume 100, Issue 8, pp. 1601 - 1602
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 09/2011, Volume 22, Issue 9, pp. 1603 - 1609
There is increasingly evidence that the interactions between vitamin D, fibroblast growth factor 23 (FGF-23), and klotho form an endocrine axis for calcium and...
OXIDATIVE STRESS | SPONTANEOUSLY HYPERTENSIVE-RATS | PHOSPHATE HOMEOSTASIS | SECRETED KLOTHO PROTEIN | COMBINATION THERAPY | HEMODIALYSIS-PATIENTS | 25-HYDROXYVITAMIN D | GENE-EXPRESSION | DOWN-REGULATION | 1,25-DIHYDROXYVITAMIN D-3 | UMCG Approved | RENAL FIBROSIS | AT RECEPTOR | UROLOGY & NEPHROLOGY | CA2+ CHANNEL | KLOTHO GENE | ANTIAGING GENE | Renal Insufficiency, Chronic - metabolism | Fibroblast Growth Factors - metabolism | Vitamin D - metabolism | Renin-Angiotensin System | Humans | Glucuronidase - metabolism | Up Front Matters
OXIDATIVE STRESS | SPONTANEOUSLY HYPERTENSIVE-RATS | PHOSPHATE HOMEOSTASIS | SECRETED KLOTHO PROTEIN | COMBINATION THERAPY | HEMODIALYSIS-PATIENTS | 25-HYDROXYVITAMIN D | GENE-EXPRESSION | DOWN-REGULATION | 1,25-DIHYDROXYVITAMIN D-3 | UMCG Approved | RENAL FIBROSIS | AT RECEPTOR | UROLOGY & NEPHROLOGY | CA2+ CHANNEL | KLOTHO GENE | ANTIAGING GENE | Renal Insufficiency, Chronic - metabolism | Fibroblast Growth Factors - metabolism | Vitamin D - metabolism | Renin-Angiotensin System | Humans | Glucuronidase - metabolism | Up Front Matters
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 09/2017, Volume 102, Issue 3, pp. 481 - 492
This review provides an overview of the clinical value of the most relevant renal biomarkers, focusing on two main clinical conditions: acute kidney injury and...
CARDIAC TROPONIN | ACUTE KIDNEY INJURY | GLOMERULAR-FILTRATION-RATE | DIETARY-SODIUM RESTRICTION | URINARY BIOMARKERS | CYSTATIN-C | RISK | PHARMACOLOGY & PHARMACY | HIGHER ALBUMINURIA | GELATINASE-ASSOCIATED LIPOCALIN | COLLABORATIVE METAANALYSIS | Biomarkers - metabolism | Kidney - metabolism | Humans | Acute Kidney Injury - physiopathology | Renal Insufficiency, Chronic - physiopathology | Kidney - physiopathology | Kidney Function Tests | Treatment outcome | Care and treatment | Research | Biological markers | Analysis | Acute renal failure
CARDIAC TROPONIN | ACUTE KIDNEY INJURY | GLOMERULAR-FILTRATION-RATE | DIETARY-SODIUM RESTRICTION | URINARY BIOMARKERS | CYSTATIN-C | RISK | PHARMACOLOGY & PHARMACY | HIGHER ALBUMINURIA | GELATINASE-ASSOCIATED LIPOCALIN | COLLABORATIVE METAANALYSIS | Biomarkers - metabolism | Kidney - metabolism | Humans | Acute Kidney Injury - physiopathology | Renal Insufficiency, Chronic - physiopathology | Kidney - physiopathology | Kidney Function Tests | Treatment outcome | Care and treatment | Research | Biological markers | Analysis | Acute renal failure
Journal Article
Current Drug Targets, ISSN 1389-4501, 2011, Volume 12, Issue 1, pp. 1 - 3
Journal Article
NEW ENGLAND JOURNAL OF MEDICINE, ISSN 0028-4793, 06/2010, Volume 362, Issue 23, pp. 2224 - 2225
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 11/2013, Volume 24, Issue 11, pp. 1863 - 1871
Despite renin-angiotensin-aldosterone system blockade, which retards progression of CKD by reducing proteinuria, many patients with CKD have residual...
GLOMERULAR-FILTRATION-RATE | NONDIABETIC RENAL-DISEASE | RENIN-ANGIOTENSIN SYSTEM | CARDIOVASCULAR EVENTS | D-RECEPTOR ACTIVATION | CONVERTING ENZYME-INHIBITORS | RANDOMIZED CONTROLLED-TRIAL | TYPE-2 DIABETIC-NEPHROPATHY | CHRONIC KIDNEY-DISEASE | POST-HOC ANALYSIS | UROLOGY & NEPHROLOGY | Proteinuria - drug therapy | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Humans | Vitamin D - analogs & derivatives | Vitamin D - therapeutic use | Angiotensin Receptor Antagonists - therapeutic use | Renal Insufficiency, Chronic - physiopathology | Randomized Controlled Trials as Topic | Renal Insufficiency, Chronic - drug therapy | Clinical Epidemiology
GLOMERULAR-FILTRATION-RATE | NONDIABETIC RENAL-DISEASE | RENIN-ANGIOTENSIN SYSTEM | CARDIOVASCULAR EVENTS | D-RECEPTOR ACTIVATION | CONVERTING ENZYME-INHIBITORS | RANDOMIZED CONTROLLED-TRIAL | TYPE-2 DIABETIC-NEPHROPATHY | CHRONIC KIDNEY-DISEASE | POST-HOC ANALYSIS | UROLOGY & NEPHROLOGY | Proteinuria - drug therapy | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Humans | Vitamin D - analogs & derivatives | Vitamin D - therapeutic use | Angiotensin Receptor Antagonists - therapeutic use | Renal Insufficiency, Chronic - physiopathology | Randomized Controlled Trials as Topic | Renal Insufficiency, Chronic - drug therapy | Clinical Epidemiology
Journal Article
Pharmacological Research, ISSN 1043-6618, 05/2016, Volume 107, pp. 344 - 351
Pharmacological blockade of the renin-angiotensin-aldosterone system (RAAS) by angiotensin converting enzyme inhibitors or angiotensin receptor blockers is the...
Salt | Renin-angiotensin-aldosterone system | Chronic kidney disease | Angiotensin receptor blockade | Sodium | Angiotensin converting enzyme blockade | ANGIOTENSIN-ALDOSTERONE SYSTEM | ACE-INHIBITION | MEMBRANOUS NEPHROPATHY | DIABETIC-NEPHROPATHY | POTASSIUM EXCRETION | BLOOD-PRESSURE | DIETARY-SODIUM | CONVERTING ENZYME-INHIBITION | REGULATORY T-CELLS | PHARMACOLOGY & PHARMACY | CHRONIC KIDNEY-DISEASE | Animals | Kidney - drug effects | Humans | Diet, Sodium-Restricted | Heart - drug effects | Renin-Angiotensin System - drug effects | Renal Insufficiency, Chronic - diet therapy | Sodium Chloride, Dietary | Kidney diseases | Medical research | Enzyme inhibitors | Corticosteroids | Chronic kidney failure | Analysis | Angiotensin converting enzyme | Angiotensin | Medicine, Experimental | Organ transplant recipients | T cells
Salt | Renin-angiotensin-aldosterone system | Chronic kidney disease | Angiotensin receptor blockade | Sodium | Angiotensin converting enzyme blockade | ANGIOTENSIN-ALDOSTERONE SYSTEM | ACE-INHIBITION | MEMBRANOUS NEPHROPATHY | DIABETIC-NEPHROPATHY | POTASSIUM EXCRETION | BLOOD-PRESSURE | DIETARY-SODIUM | CONVERTING ENZYME-INHIBITION | REGULATORY T-CELLS | PHARMACOLOGY & PHARMACY | CHRONIC KIDNEY-DISEASE | Animals | Kidney - drug effects | Humans | Diet, Sodium-Restricted | Heart - drug effects | Renin-Angiotensin System - drug effects | Renal Insufficiency, Chronic - diet therapy | Sodium Chloride, Dietary | Kidney diseases | Medical research | Enzyme inhibitors | Corticosteroids | Chronic kidney failure | Analysis | Angiotensin converting enzyme | Angiotensin | Medicine, Experimental | Organ transplant recipients | T cells
Journal Article
Nature Genetics, ISSN 1061-4036, 10/2018, Volume 50, Issue 10, pp. 1412 - +
High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood...
CARDIOVASCULAR-DISEASE RISK | UK BIOBANK | METAANALYSIS | VARIANTS | RARE | HYPERALDOSTERONISM | COMMON | HEALTH | HYPERTENSION | GENOME-WIDE ASSOCIATION | GENETICS & HEREDITY | PREVALENCE | CARDIOVASCULAR RISK | Human Umbilical Vein Endothelial Cells | Genetic Predisposition to Disease | Genome-Wide Association Study | Life Style | Blood Pressure - genetics | Humans | Middle Aged | Risk Factors | Cells, Cultured | Male | Genetic Loci | Cardiovascular Diseases - genetics | Genetic Testing - methods | Genetics, Population - methods | Aged, 80 and over | Cardiovascular Diseases - epidemiology | Adult | Female | Aged | Polymorphism, Single Nucleotide | Hypertension - genetics | Quantitative Trait Loci | Hypertension | Health risks | Cardiovascular disease | Genomes | Risk analysis | Loci | Blood | Risk factors | Meta-analysis | Studies | Consortia | Genetic analysis | Blood pressure | Gene loci | Lifestyles | Cardiovascular diseases | Health risk assessment | Biological Sciences | Naturvetenskap | Natural Sciences | Biologiska vetenskaper
CARDIOVASCULAR-DISEASE RISK | UK BIOBANK | METAANALYSIS | VARIANTS | RARE | HYPERALDOSTERONISM | COMMON | HEALTH | HYPERTENSION | GENOME-WIDE ASSOCIATION | GENETICS & HEREDITY | PREVALENCE | CARDIOVASCULAR RISK | Human Umbilical Vein Endothelial Cells | Genetic Predisposition to Disease | Genome-Wide Association Study | Life Style | Blood Pressure - genetics | Humans | Middle Aged | Risk Factors | Cells, Cultured | Male | Genetic Loci | Cardiovascular Diseases - genetics | Genetic Testing - methods | Genetics, Population - methods | Aged, 80 and over | Cardiovascular Diseases - epidemiology | Adult | Female | Aged | Polymorphism, Single Nucleotide | Hypertension - genetics | Quantitative Trait Loci | Hypertension | Health risks | Cardiovascular disease | Genomes | Risk analysis | Loci | Blood | Risk factors | Meta-analysis | Studies | Consortia | Genetic analysis | Blood pressure | Gene loci | Lifestyles | Cardiovascular diseases | Health risk assessment | Biological Sciences | Naturvetenskap | Natural Sciences | Biologiska vetenskaper
Journal Article
BRITISH MEDICAL JOURNAL, ISSN 0959-535X, 03/2009, Volume 338, p. b425
Journal Article
American Journal of Clinical Nutrition, ISSN 0002-9165, 09/2019, Volume 110, Issue 3, pp. 641 - 651
BACKGROUND: There is growing interest in assessing a population's prevalence of inadequate nutrient intake using biomarkers. However, within-person variation...
within-person variance | TRANSFORMATION | COLLECTION | BIOMARKER | habitual intake | IODINE | PREVALENCE | DIETARY-INTAKE | kidney transplant recipient | BLOOD-PRESSURE | VARIABILITY | sodium | NUTRITION & DIETETICS | external variance | NUTRIENTS | salt intake | POTASSIUM | 24-h urine | Urine | Excretion | Salts | Sensitivity analysis | Kidneys | Data collections | Estimation | Variance | Salt | Sodium | Dogs | Data collection | Biomarkers | Collections | Kidney transplantation
within-person variance | TRANSFORMATION | COLLECTION | BIOMARKER | habitual intake | IODINE | PREVALENCE | DIETARY-INTAKE | kidney transplant recipient | BLOOD-PRESSURE | VARIABILITY | sodium | NUTRITION & DIETETICS | external variance | NUTRIENTS | salt intake | POTASSIUM | 24-h urine | Urine | Excretion | Salts | Sensitivity analysis | Kidneys | Data collections | Estimation | Variance | Salt | Sodium | Dogs | Data collection | Biomarkers | Collections | Kidney transplantation
Journal Article
Clinical Journal of the American Society of Nephrology, ISSN 1555-9041, 11/2013, Volume 8, Issue 11, pp. 1968 - 1978
BACKGROUND AND OBJECTIVES: Circulating fibroblast growth factor 23 (FGF23) is associated with adverse cardiovascular outcomes in CKD. Whether FGF23 predicts...
Multivariate Analysis | Cardiovascular Diseases | Peptide Fragments | Prospective Studies | Biological Markers | Humans | Middle Aged | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Linear Models | Male | Treatment Outcome | Kidney Transplantation | Netherlands | Natriuretic Peptide, Brain | Time Factors | Atrial Natriuretic Factor | Adult | Female | Fibroblast Growth Factors | Glycopeptides | METABOLIC SYNDROME | EVENTS | FGF-23 | DISEASE | INCREASES | UROLOGY & NEPHROLOGY | RISK | SERUM | FGF23 | LEFT-VENTRICULAR HYPERTROPHY | PEPTIDE | Atrial Natriuretic Factor - blood | Peptide Fragments - blood | Cardiovascular Diseases - blood | Cardiovascular Diseases - mortality | Natriuretic Peptide, Brain - blood | Cardiovascular Diseases - etiology | Biomarkers - blood | Fibroblast Growth Factors - blood | Glycopeptides - blood | Kidney Transplantation - mortality | Kidney Transplantation - adverse effects | Original
Multivariate Analysis | Cardiovascular Diseases | Peptide Fragments | Prospective Studies | Biological Markers | Humans | Middle Aged | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Linear Models | Male | Treatment Outcome | Kidney Transplantation | Netherlands | Natriuretic Peptide, Brain | Time Factors | Atrial Natriuretic Factor | Adult | Female | Fibroblast Growth Factors | Glycopeptides | METABOLIC SYNDROME | EVENTS | FGF-23 | DISEASE | INCREASES | UROLOGY & NEPHROLOGY | RISK | SERUM | FGF23 | LEFT-VENTRICULAR HYPERTROPHY | PEPTIDE | Atrial Natriuretic Factor - blood | Peptide Fragments - blood | Cardiovascular Diseases - blood | Cardiovascular Diseases - mortality | Natriuretic Peptide, Brain - blood | Cardiovascular Diseases - etiology | Biomarkers - blood | Fibroblast Growth Factors - blood | Glycopeptides - blood | Kidney Transplantation - mortality | Kidney Transplantation - adverse effects | Original
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 01/2016, Volume 27, Issue 1, pp. 239 - 248
Calciprotein particle maturation time (T-50) in serum is a novel measure of individual blood calcification propensity. To determine the clinical relevance of...
MINERAL COMPLEX | CORONARY-ARTERY CALCIFICATION | CALCIUM-PHOSPHATE | FORMATION IN-VITRO | GROWTH-FACTOR 23 | PREDIALYSIS CKD | CONTAINING CALCIPROTEIN PARTICLES | SERUM | NATRIURETIC PEPTIDE | FETUIN-A | MORTALITY | DISEASE | UROLOGY & NEPHROLOGY | Predictive Value of Tests | Prospective Studies | Humans | Middle Aged | Risk Factors | Calcinosis - mortality | Postoperative Complications - blood | Male | Survival Rate | Kidney Transplantation | Postoperative Complications - epidemiology | Calcinosis - blood | Postoperative Complications - mortality | Calcinosis - epidemiology | Female | Calcium Pyrophosphate - blood | Clinical Research | calcification propensity | renal transplantation | serum T50 | calciprotein particles | graft failure | mortality risk
MINERAL COMPLEX | CORONARY-ARTERY CALCIFICATION | CALCIUM-PHOSPHATE | FORMATION IN-VITRO | GROWTH-FACTOR 23 | PREDIALYSIS CKD | CONTAINING CALCIPROTEIN PARTICLES | SERUM | NATRIURETIC PEPTIDE | FETUIN-A | MORTALITY | DISEASE | UROLOGY & NEPHROLOGY | Predictive Value of Tests | Prospective Studies | Humans | Middle Aged | Risk Factors | Calcinosis - mortality | Postoperative Complications - blood | Male | Survival Rate | Kidney Transplantation | Postoperative Complications - epidemiology | Calcinosis - blood | Postoperative Complications - mortality | Calcinosis - epidemiology | Female | Calcium Pyrophosphate - blood | Clinical Research | calcification propensity | renal transplantation | serum T50 | calciprotein particles | graft failure | mortality risk
Journal Article
Lancet Diabetes & Endocrinology, The, ISSN 2213-8587, 2014, Volume 2, Issue 9, pp. 719 - 729
Summary Background Low plasma 25-hydroxyvitamin D (25[OH]D) concentration is associated with high arterial blood pressure and hypertension risk, but whether...
Endocrinology & Metabolism | Other | TRIAL | METAANALYSIS | RENIN-ANGIOTENSIN SYSTEM | D SUPPLEMENTATION | DISEASE | GENETIC-VARIANTS | OUTCOMES | HEALTH | KIDNEY | GENOME-WIDE ASSOCIATION | ENDOCRINOLOGY & METABOLISM | Body Mass Index | Genetic Predisposition to Disease | Vitamin D Deficiency - genetics | Humans | Middle Aged | Male | Randomized Controlled Trials as Topic | Hypertension - blood | Cytochrome P450 Family 2 | Vitamin D Deficiency - prevention & control | Phenotype | Cholestanetriol 26-Monooxygenase - genetics | Vitamin D Deficiency - blood | Mendelian Randomization Analysis | Hypertension - prevention & control | Adult | Female | Oxidoreductases Acting on CH-CH Group Donors - genetics | Vitamin D - administration & dosage | Vitamin D - analogs & derivatives | Polymorphism, Single Nucleotide | Hypertension - genetics | Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
Endocrinology & Metabolism | Other | TRIAL | METAANALYSIS | RENIN-ANGIOTENSIN SYSTEM | D SUPPLEMENTATION | DISEASE | GENETIC-VARIANTS | OUTCOMES | HEALTH | KIDNEY | GENOME-WIDE ASSOCIATION | ENDOCRINOLOGY & METABOLISM | Body Mass Index | Genetic Predisposition to Disease | Vitamin D Deficiency - genetics | Humans | Middle Aged | Male | Randomized Controlled Trials as Topic | Hypertension - blood | Cytochrome P450 Family 2 | Vitamin D Deficiency - prevention & control | Phenotype | Cholestanetriol 26-Monooxygenase - genetics | Vitamin D Deficiency - blood | Mendelian Randomization Analysis | Hypertension - prevention & control | Adult | Female | Oxidoreductases Acting on CH-CH Group Donors - genetics | Vitamin D - administration & dosage | Vitamin D - analogs & derivatives | Polymorphism, Single Nucleotide | Hypertension - genetics | Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
Journal Article