Nederlands Tijdschrift voor Geneeskunde, ISSN 0028-2162, 07/2010, Volume 154, Issue 26, pp. 1252 - 1256
Journal Article
Nederlands tijdschrift voor geneeskunde, 2010, Volume 154, Issue 13, p. A499
Journal Article
Trials, ISSN 1745-6215, 2014, Volume 15, Issue 1, p. 343
Endovascular or intra-arterial treatment (IAT) increases the likelihood of recanalization in patients with acute ischemic stroke caused by a proximal...
Urokinase | Thrombectomy | Alteplase | Endovascular treatment | Acute ischemic stroke | Randomized controlled trial | Stent | MEDICINE, RESEARCH & EXPERIMENTAL | REVASCULARIZATION | TISSUE-PLASMINOGEN ACTIVATOR | INFUSION | PROUROKINASE | IMPACT | THERAPY | PARALLEL-GROUP | INTRAARTERIAL THROMBOLYSIS | OCCLUSION | Endovascular Procedures | Stroke - surgery | Sample Size | Humans | Clinical Protocols | Brain Ischemia - surgery
Urokinase | Thrombectomy | Alteplase | Endovascular treatment | Acute ischemic stroke | Randomized controlled trial | Stent | MEDICINE, RESEARCH & EXPERIMENTAL | REVASCULARIZATION | TISSUE-PLASMINOGEN ACTIVATOR | INFUSION | PROUROKINASE | IMPACT | THERAPY | PARALLEL-GROUP | INTRAARTERIAL THROMBOLYSIS | OCCLUSION | Endovascular Procedures | Stroke - surgery | Sample Size | Humans | Clinical Protocols | Brain Ischemia - surgery
Journal Article
Nederlands tijdschrift voor geneeskunde, ISSN 0028-2162, 2010, Volume 154, p. A933
Two patients presented to Accidents and Emergency with severe neck pain: a 70-year-old woman with acute, severe neck pain, which had developed a few days after...
Calcinosis - diagnosis | Calcinosis - drug therapy | Diclofenac - therapeutic use | Calcinosis - complications | Humans | Middle Aged | Tomography, X-Ray Computed | Treatment Outcome | Neck Pain - etiology | Tendinopathy - complications | Neck Pain - diagnosis | Magnetic Resonance Imaging | Tendinopathy - diagnosis | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Female | Aged | Neck Pain - drug therapy | Neck - physiopathology | Tendinopathy - drug therapy
Calcinosis - diagnosis | Calcinosis - drug therapy | Diclofenac - therapeutic use | Calcinosis - complications | Humans | Middle Aged | Tomography, X-Ray Computed | Treatment Outcome | Neck Pain - etiology | Tendinopathy - complications | Neck Pain - diagnosis | Magnetic Resonance Imaging | Tendinopathy - diagnosis | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Female | Aged | Neck Pain - drug therapy | Neck - physiopathology | Tendinopathy - drug therapy
Journal Article
Nederlands tijdschrift voor geneeskunde, 2010, Volume 154, Issue 26, p. A933
Journal Article
PLoS ONE, ISSN 1932-6203, 2015, Volume 10, Issue 3, p. e0119409
It has been suggested that CT Perfusion acquisition times <60 seconds are too short to capture the complete in and out-wash of contrast in the tissue,...
REVASCULARIZATION | DIFFUSION MISMATCH | THERAPY | MRI | MULTIDISCIPLINARY SCIENCES | QUANTITATIVE ASSESSMENT | INFARCT CORE | CEREBRAL-BLOOD-FLOW | SELECTION | COMPUTED-TOMOGRAPHY PERFUSION | BRAIN | Cerebrovascular Circulation - physiology | Stroke - diagnostic imaging | Humans | Middle Aged | Perfusion Imaging - methods | Tomography, X-Ray Computed - methods | Male | Brain Ischemia - physiopathology | Heart Ventricles - diagnostic imaging | Stroke - physiopathology | Heart Ventricles - physiopathology | Time Factors | Aged, 80 and over | Adult | Female | Aged | Phantoms, Imaging | Brain Ischemia - diagnostic imaging | Stroke (Disease) | Ischemia | CT imaging | Cores | Occlusion | Stroke | Medical imaging | Perfusion | Data processing | Attenuation | Patients | Blood | Penumbras
REVASCULARIZATION | DIFFUSION MISMATCH | THERAPY | MRI | MULTIDISCIPLINARY SCIENCES | QUANTITATIVE ASSESSMENT | INFARCT CORE | CEREBRAL-BLOOD-FLOW | SELECTION | COMPUTED-TOMOGRAPHY PERFUSION | BRAIN | Cerebrovascular Circulation - physiology | Stroke - diagnostic imaging | Humans | Middle Aged | Perfusion Imaging - methods | Tomography, X-Ray Computed - methods | Male | Brain Ischemia - physiopathology | Heart Ventricles - diagnostic imaging | Stroke - physiopathology | Heart Ventricles - physiopathology | Time Factors | Aged, 80 and over | Adult | Female | Aged | Phantoms, Imaging | Brain Ischemia - diagnostic imaging | Stroke (Disease) | Ischemia | CT imaging | Cores | Occlusion | Stroke | Medical imaging | Perfusion | Data processing | Attenuation | Patients | Blood | Penumbras
Journal Article
PLoS ONE, ISSN 1932-6203, 2014, Volume 9, Issue 7, p. e101985
Thrombus characterization is increasingly considered important in predicting treatment success for patients with acute ischemic stroke. The lack of intensity...
MIDDLE CEREBRAL-ARTERY | RECONSTRUCTIONS | THROMBOLYSIS | MULTIDISCIPLINARY SCIENCES | COMPUTED-TOMOGRAPHY | RECANALIZATION | Reproducibility of Results | Stroke - diagnostic imaging | Humans | Middle Aged | Stroke - diagnosis | Radiographic Image Enhancement - methods | Tomography, X-Ray Computed - methods | Male | Intracranial Thrombosis - therapy | Cerebral Angiography - methods | Radiographic Image Interpretation, Computer-Assisted - methods | Female | Intracranial Thrombosis - diagnosis | Retrospective Studies | Observer Variation | Pattern Recognition, Automated - methods | Stroke - therapy | Intracranial Thrombosis - diagnostic imaging | Stroke (Disease) | CT imaging | Care and treatment | Ischemia | Angiography | Analysis | Thrombosis | Blood clot | Occlusion | Stroke | Automation | Medical imaging | Segmentation | Image processing | Bias | Correlation coefficients | Hematocrit | Delineation | Patients | Coefficient of variation | Blood clots | Studies | Image segmentation | Computed tomography | Correlation analysis | Health informatics | Biomedical engineering | Image contrast | Veins & arteries
MIDDLE CEREBRAL-ARTERY | RECONSTRUCTIONS | THROMBOLYSIS | MULTIDISCIPLINARY SCIENCES | COMPUTED-TOMOGRAPHY | RECANALIZATION | Reproducibility of Results | Stroke - diagnostic imaging | Humans | Middle Aged | Stroke - diagnosis | Radiographic Image Enhancement - methods | Tomography, X-Ray Computed - methods | Male | Intracranial Thrombosis - therapy | Cerebral Angiography - methods | Radiographic Image Interpretation, Computer-Assisted - methods | Female | Intracranial Thrombosis - diagnosis | Retrospective Studies | Observer Variation | Pattern Recognition, Automated - methods | Stroke - therapy | Intracranial Thrombosis - diagnostic imaging | Stroke (Disease) | CT imaging | Care and treatment | Ischemia | Angiography | Analysis | Thrombosis | Blood clot | Occlusion | Stroke | Automation | Medical imaging | Segmentation | Image processing | Bias | Correlation coefficients | Hematocrit | Delineation | Patients | Coefficient of variation | Blood clots | Studies | Image segmentation | Computed tomography | Correlation analysis | Health informatics | Biomedical engineering | Image contrast | Veins & arteries
Journal Article
Nederlands tijdschrift voor geneeskunde, ISSN 0028-2162, 2010, Volume 154, p. A499
A 72-year-old woman had reduced vision due to orbital emphysema after a blow-out fracture.
Epistaxis - etiology | Epistaxis - therapy | Tampons, Surgical - adverse effects | Humans | Emphysema - diagnosis | Female | Aged | Orbital Fractures - diagnosis | Blindness - etiology | Orbital Fractures - complications
Epistaxis - etiology | Epistaxis - therapy | Tampons, Surgical - adverse effects | Humans | Emphysema - diagnosis | Female | Aged | Orbital Fractures - diagnosis | Blindness - etiology | Orbital Fractures - complications
Journal Article
Plant Cell, ISSN 1040-4651, 12/2016, Volume 28, Issue 12, pp. 2937 - 2951
Organ formation in animals and plants relies on precise control of cell state transitions to turn stem cell daughters into fully differentiated cells. In...
RESEARCH ARTICLES | Plant Science | Journal Article | Cell Biology | TRANSCRIPTION FACTOR-BINDING | STEM-CELLS | AINTEGUMENTA | BIOCHEMISTRY & MOLECULAR BIOLOGY | NICHE | PLANT SCIENCES | CELL BIOLOGY | THALIANA | AUXIN BIOSYNTHESIS | MERISTEM | PLANTS | PROTEINS | EXPRESSION | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | Transcription Factors - metabolism | Cell Differentiation - genetics | Arabidopsis Proteins - genetics | Gene Regulatory Networks - genetics | Arabidopsis - cytology | Gene Expression Regulation, Plant | Plant Roots - genetics | Plant Roots - cytology | Transcription Factors - genetics | Botanical research | Arabidopsis | Growth | Roots (Botany) | Genetic aspects | Research | Genetic regulation | Cell differentiation | Arabidopsis thaliana | Stem cells | Biosystematics | Plant Developmental Biology | BIOS Applied Bioinformatics | EPS | Bioinformatica | Biosystematiek | Bioinformatics | PRI BIOS Applied Bioinformatics
RESEARCH ARTICLES | Plant Science | Journal Article | Cell Biology | TRANSCRIPTION FACTOR-BINDING | STEM-CELLS | AINTEGUMENTA | BIOCHEMISTRY & MOLECULAR BIOLOGY | NICHE | PLANT SCIENCES | CELL BIOLOGY | THALIANA | AUXIN BIOSYNTHESIS | MERISTEM | PLANTS | PROTEINS | EXPRESSION | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | Transcription Factors - metabolism | Cell Differentiation - genetics | Arabidopsis Proteins - genetics | Gene Regulatory Networks - genetics | Arabidopsis - cytology | Gene Expression Regulation, Plant | Plant Roots - genetics | Plant Roots - cytology | Transcription Factors - genetics | Botanical research | Arabidopsis | Growth | Roots (Botany) | Genetic aspects | Research | Genetic regulation | Cell differentiation | Arabidopsis thaliana | Stem cells | Biosystematics | Plant Developmental Biology | BIOS Applied Bioinformatics | EPS | Bioinformatica | Biosystematiek | Bioinformatics | PRI BIOS Applied Bioinformatics
Journal Article
Neuron, ISSN 0896-6273, 03/2018, Volume 97, Issue 6, pp. 1268 - 1283.e6
To identify novel genes associated with ALS, we undertook two lines of investigation. We carried out a genome-wide association study comparing 20,806 ALS cases...
WGS | GWAS | WES | KIF5A | ALS | axonal transport | cargo | MOTOR-NEURONS | TARGETED DISRUPTION | GENOTYPE IMPUTATION | DNA-DAMAGE | AXONAL-TRANSPORT | AMYOTROPHIC-LATERAL-SCLEROSIS | MUTATIONS | KINESIN HEAVY-CHAIN | HEXANUCLEOTIDE REPEAT | NEUROSCIENCES | FAMILIAL ALS | Genetic research | Genes | Analysis | Genomics | Phenotypes | Disease | Neurodegenerative diseases | Pathogenesis | Homeostasis | Amyotrophic lateral sclerosis | Genomes | Risk factors | Consortia | Hereditary spastic paraplegia | Proteins | Paraplegia | Charcot-Marie-Tooth disease | Cytoskeleton | Mutation | Spastic paraplegia | Life Sciences | Basic Medicine | Neurosciences | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Neurovetenskaper
WGS | GWAS | WES | KIF5A | ALS | axonal transport | cargo | MOTOR-NEURONS | TARGETED DISRUPTION | GENOTYPE IMPUTATION | DNA-DAMAGE | AXONAL-TRANSPORT | AMYOTROPHIC-LATERAL-SCLEROSIS | MUTATIONS | KINESIN HEAVY-CHAIN | HEXANUCLEOTIDE REPEAT | NEUROSCIENCES | FAMILIAL ALS | Genetic research | Genes | Analysis | Genomics | Phenotypes | Disease | Neurodegenerative diseases | Pathogenesis | Homeostasis | Amyotrophic lateral sclerosis | Genomes | Risk factors | Consortia | Hereditary spastic paraplegia | Proteins | Paraplegia | Charcot-Marie-Tooth disease | Cytoskeleton | Mutation | Spastic paraplegia | Life Sciences | Basic Medicine | Neurosciences | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Neurovetenskaper
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 397 - 12
BRCA1-mutated breast cancer is primarily driven by DNA copy-number alterations (CNAs) containing large numbers of candidate driver genes. Validation of these...
CELLS | MAMMARY-TUMORS | LANDSCAPE | PATHWAY | MYC | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | E-CADHERIN | COPY-NUMBER ALTERATION | P53 | MCL1 | CRISPR | Animal models | BRCA1 protein | Genes | Embryo cells | Stem cell transplantation | Poly(ADP-ribose) polymerase | Breast cancer | Myc protein | Mcl-1 protein | Gene disruption | Stem cells | Breast | Tumorigenesis | Genetic engineering | Inhibition | Disruption | Iterative methods | PTEN protein | Deoxyribonucleic acid--DNA | Cancer | Tumors
CELLS | MAMMARY-TUMORS | LANDSCAPE | PATHWAY | MYC | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | E-CADHERIN | COPY-NUMBER ALTERATION | P53 | MCL1 | CRISPR | Animal models | BRCA1 protein | Genes | Embryo cells | Stem cell transplantation | Poly(ADP-ribose) polymerase | Breast cancer | Myc protein | Mcl-1 protein | Gene disruption | Stem cells | Breast | Tumorigenesis | Genetic engineering | Inhibition | Disruption | Iterative methods | PTEN protein | Deoxyribonucleic acid--DNA | Cancer | Tumors
Journal Article
Biomaterials, ISSN 0142-9612, 2014, Volume 35, Issue 26, pp. 7441 - 7451
Abstract A resorbable bone graft substitute should mimic native bone in its capacity to support bone formation and be remodeled by osteoclasts (OCl) or other...
Advanced Basic Science | Dentistry | Calcium phosphate | Foreign body giant cell | Osteoclast | Microstructure | Topography | METIS-309529 | IR-95160 | MATERIALS SCIENCE, BIOMATERIALS | CERAMIC DEGRADATION | ENGINEERING, BIOMEDICAL | MULTINUCLEATED GIANT-CELLS | RESISTANT ACID-PHOSPHATASE | IMPLANTS | HYDROXYAPATITE | IN-VITRO | BONE-FORMATION | MACROPHAGE FUSION | BIOMATERIALS | EXPRESSION | Bone Substitutes - metabolism | Cell Survival | Humans | Surface Properties | Cells, Cultured | Calcium Phosphates - chemistry | Cell Differentiation | Osteoclasts - cytology | Calcium Phosphates - metabolism | Osteoclasts - metabolism | Bone Substitutes - chemistry | Architecture | Muscle proteins | Analysis | Cells | Phosphates | Biomedical materials | TCP (protocol) | Surface chemistry | Biocompatibility | Bones | Grafting
Advanced Basic Science | Dentistry | Calcium phosphate | Foreign body giant cell | Osteoclast | Microstructure | Topography | METIS-309529 | IR-95160 | MATERIALS SCIENCE, BIOMATERIALS | CERAMIC DEGRADATION | ENGINEERING, BIOMEDICAL | MULTINUCLEATED GIANT-CELLS | RESISTANT ACID-PHOSPHATASE | IMPLANTS | HYDROXYAPATITE | IN-VITRO | BONE-FORMATION | MACROPHAGE FUSION | BIOMATERIALS | EXPRESSION | Bone Substitutes - metabolism | Cell Survival | Humans | Surface Properties | Cells, Cultured | Calcium Phosphates - chemistry | Cell Differentiation | Osteoclasts - cytology | Calcium Phosphates - metabolism | Osteoclasts - metabolism | Bone Substitutes - chemistry | Architecture | Muscle proteins | Analysis | Cells | Phosphates | Biomedical materials | TCP (protocol) | Surface chemistry | Biocompatibility | Bones | Grafting
Journal Article