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Psychoneuroendocrinology, ISSN 0306-4530, 12/2019, Volume 110, p. 104429
We aimed to evaluate the association between measures of adiposity with depressive mood and specific depressive symptoms. This study was performed in the... 
Body mass index | Obesity | Depression | Abdominal fat | Body fat distribution | Depressive disorder
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 09/2019, Volume 10, Issue 1, pp. 4130 - 19
Journal Article
by Kilpeläinen, Tuomas O and Bentley, Amy R and Noordam, Raymond and Sung, Yun Ju and Schwander, Karen and Winkler, Thomas W and Jakupović, Hermina and Chasman, Daniel I and Manning, Alisa and Ntalla, Ioanna and Aschard, Hugues and Brown, Michael R and de las Fuentes, Lisa and Franceschini, Nora and Guo, Xiuqing and Vojinovic, Dina and Aslibekyan, Stella and Feitosa, Mary F and Kho, Minjung and Musani, Solomon K and Richard, Melissa and Wang, Heming and Wang, Zhe and Bartz, Traci M and Bielak, Lawrence F and Campbell, Archie and Dorajoo, Rajkumar and Fisher, Virginia and Hartwig, Fernando P and Horimoto, Andrea R. V. R and Li, Changwei and Lohman, Kurt K and Marten, Jonathan and Sim, Xueling and Smith, Albert V and Tajuddin, Salman M and Alver, Maris and Amini, Marzyeh and Boissel, Mathilde and Chai, Jin Fang and Chen, Xu and Divers, Jasmin and Evangelou, Evangelos and Gao, Chuan and Graff, Mariaelisa and Harris, Sarah E and He, Meian and Hsu, Fang-Chi and Jackson, Anne U and Zhao, Jing Hua and Kraja, Aldi T and Kühnel, Brigitte and Laguzzi, Federica and Lyytikäinen, Leo-Pekka and Nolte, Ilja M and Rauramaa, Rainer and Riaz, Muhammad and Robino, Antonietta and Rueedi, Rico and Stringham, Heather M and Takeuchi, Fumihiko and van der Most, Peter J and Varga, Tibor V and Verweij, Niek and Ware, Erin B and Wen, Wanqing and Li, Xiaoyin and Yanek, Lisa R and Amin, Najaf and Arnett, Donna K and Boerwinkle, Eric and Brumat, Marco and Cade, Brian and Canouil, Mickaël and Chen, Yii-Der Ida and Concas, Maria Pina and Connell, John and de Mutsert, Renée and de Silva, H. Janaka and de Vries, Paul S and Demirkan, Ayşe and Ding, Jingzhong and Eaton, Charles B and Faul, Jessica D and Friedlander, Yechiel and Gabriel, Kelley P and Ghanbari, Mohsen and Giulianini, Franco and Gu, Chi Charles and Gu, Dongfeng and Harris, Tamara B and He, Jiang and Heikkinen, Sami and Heng, Chew-Kiat and Hunt, Steven C and Ikram, M. Arfan and Jonas, Jost B and Koh, Woon-Puay and Komulainen, Pirjo and Krieger, Jose E and ... and Lifelines Cohort Study
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1 - 11
Many genetic loci affect circulating lipid levels, but it remains unknown whether lifestyle factors, such as physical activity, modify these genetic effects.... 
INDIVIDUALS | METAANALYSIS | CARBOXYLASE | SNP | MULTIDISCIPLINARY SCIENCES | WIDE ASSOCIATION | REVEAL | EXERCISE | Lipoproteins (low density) | Physical activity | Muscles | Lipids | Genomes | Metabolism | Loci | Low density lipoprotein | Blood | Cholesterol | Genetic effects | Gene loci | Lipid metabolism | Lipoproteins (high density)
Journal Article
Metabolomics, ISSN 1573-3882, 10/2019, Volume 15, Issue 10, pp. 1 - 12
Excess visceral and liver fat are known risk factors for cardiometabolic disorders. Metabolomics might allow for easier quantification of these ectopic fat... 
Life Sciences | Biochemistry, general | Biomedicine, general | Metabolomics | Liver fat | Biomarkers | Molecular Medicine | Visceral adipose tissue | Developmental Biology | Cell Biology | Obesity | Metabolites | Biological markers | Epidemiology | Liver | Risk factors
Journal Article
by Tin, Adrienne and Marten, Jonathan and Halperin Kuhns, Victoria L and Li, Yong and Wuttke, Matthias and Kirsten, Holger and Sieber, Karsten B and Qiu, Chengxiang and Gorski, Mathias and Yu, Zhi and Giri, Ayush and Sveinbjornsson, Gardar and Li, Man and Chu, Audrey Y and Hoppmann, Anselm and O’Connor, Luke J and Prins, Bram and Nutile, Teresa and Noce, Damia and Akiyama, Masato and Cocca, Massimiliano and Ghasemi, Sahar and van der Most, Peter J and Horn, Katrin and Xu, Yizhe and Fuchsberger, Christian and Sedaghat, Sanaz and Afaq, Saima and Amin, Najaf and Ärnlöv, Johan and Bakker, Stephan J. L and Bansal, Nisha and Baptista, Daniela and Bergmann, Sven and Biggs, Mary L and Biino, Ginevra and Boerwinkle, Eric and Bottinger, Erwin P and Boutin, Thibaud S and Brumat, Marco and Burkhardt, Ralph and Campana, Eric and Campbell, Archie and Campbell, Harry and Carroll, Robert J and Catamo, Eulalia and Chambers, John C and Ciullo, Marina and Concas, Maria Pina and Coresh, Josef and Corre, Tanguy and Cusi, Daniele and Felicita, Sala Cinzia and de Borst, Martin H and De Grandi, Alessandro and de Mutsert, Renée and de Vries, Aiko P. J and Delgado, Graciela and Demirkan, Ayşe and Devuyst, Olivier and Dittrich, Katalin and Eckardt, Kai-Uwe and Ehret, Georg and Endlich, Karlhans and Evans, Michele K and Gansevoort, Ron T and Gasparini, Paolo and Giedraitis, Vilmantas and Gieger, Christian and Girotto, Giorgia and Gögele, Martin and Gordon, Scott D and Gudbjartsson, Daniel F and Gudnason, Vilmundur and Haller, Toomas and Hamet, Pavel and Harris, Tamara B and Hayward, Caroline and Hicks, Andrew A and Hofer, Edith and Holm, Hilma and Huang, Wei and Hutri-Kähönen, Nina and Hwang, Shih-Jen and Ikram, M. Arfan and Lewis, Raychel M and Ingelsson, Erik and Jakobsdottir, Johanna and Jonsdottir, Ingileif and Jonsson, Helgi and Joshi, Peter K and Josyula, Navya Shilpa and Jung, Bettina and Kähönen, Mika and Kamatani, Yoichiro and Kanai, Masahiro and Kerr, Shona M and Kiess, Wieland and Kleber, Marcus E and Koenig, Wolfgang and ... and V. A. Million Veteran Program and German Chronic Kidney Disease Study and Lifelines Cohort Study
Nature Genetics, ISSN 1061-4036, 10/2019, Volume 51, Issue 10, pp. 1459 - 1474
Elevated serum urate levels cause gout and correlate with cardiometabolic diseases via poorly understood mechanisms. We performed a trans-ancestry genome-wide... 
Regulators | Transcription factors | Transcription | Liver | Genes | Gout | African Americans | Genomes | Mapping | Data bases | Genetic analysis | Population | Rheumatism | Hepatocyte nuclear factor 4 | Bioinformatics | Kidneys | Organs | Uric acid | Metabolism | Gene expression | Loci | Meta-analysis | Studies | Pleiotropy | Gene loci | Gene mapping | Transporter | Binding sites | Open access
Journal Article
Journal of Clinical Medicine, ISSN 2077-0383, 09/2019, Volume 8, Issue 10, p. 1559
We aimed to investigate the role of the amount of visceral fat and liver fat in the association between adult weight change and insulin resistance at middle... 
body weight changes | fatty liver | visceral fat | insulin resistance
Journal Article
by Spracklen, Cassandra N and Karaderi, Tugce and Yaghootkar, Hanieh and Schurmann, Claudia and Fine, Rebecca S and Kutalik, Zoltan and Preuss, Michael H and Lu, Yingchang and Wittemans, Laura B.L and Adair, Linda S and Allison, Matthew and Amin, Najaf and Auer, Paul L and Bartz, Traci M and Blüher, Matthias and Boehnke, Michael and Borja, Judith B and Bork-Jensen, Jette and Broer, Linda and Chasman, Daniel I and Chen, Yii-Der Ida and Chirstofidou, Paraskevi and Demirkan, Ayse and van Duijn, Cornelia M and Feitosa, Mary F and Garcia, Melissa E and Graff, Mariaelisa and Grallert, Harald and Grarup, Niels and Guo, Xiuqing and Haesser, Jeffrey and Hansen, Torben and Harris, Tamara B and Highland, Heather M and Hong, Jaeyoung and Ikram, M. Arfan and Ingelsson, Erik and Jackson, Rebecca and Jousilahti, Pekka and Kähönen, Mika and Kizer, Jorge R and Kovacs, Peter and Kriebel, Jennifer and Laakso, Markku and Lange, Leslie A and Lehtimäki, Terho and Li, Jin and Li-Gao, Ruifang and Lind, Lars and Luan, Jian’an and Lyytikäinen, Leo-Pekka and MacGregor, Stuart and Mackey, David A and Mahajan, Anubha and Mangino, Massimo and Männistö, Satu and McCarthy, Mark I and McKnight, Barbara and Medina-Gomez, Carolina and Meigs, James B and Molnos, Sophie and Mook-Kanamori, Dennis and Morris, Andrew P and de Mutsert, Renee and Nalls, Mike A and Nedeljkovic, Ivana and North, Kari E and Pennell, Craig E and Pradhan, Aruna D and Province, Michael A and Raitakari, Olli T and Raulerson, Chelsea K and Reiner, Alex P and Ridker, Paul M and Ripatti, Samuli and Roberston, Neil and Rotter, Jerome I and Salomaa, Veikko and Sandoval-Zárate, America A and Sitlani, Colleen M and Spector, Tim D and Strauch, Konstantin and Stumvoll, Michael and Taylor, Kent D and Thuesen, Betina and Tönjes, Anke and Uitterlinden, Andre G and Venturini, Cristina and Walker, Mark and Wang, Shuai and Wang, Carol A and Wareham, Nicholas J and Willems, Sara M and Willems van Dijk, Ko and Wilson, James G and Wu, Ying and Yao, Jie and Young, Kristin L and Langenberg, Claudia and Frayling, Timothy M and ...
The American Journal of Human Genetics, ISSN 0002-9297, 09/2019, Volume 105, Issue 3, pp. 670 - 671
Journal Article
by Huang, Tao and Wang, Tiange and Zheng, Yan and Ellervik, Christina and Li, Xiang and Gao, Meng and Fang, Zhe and Chai, Jin-Fang and Ahluwalia, Tarun veer S and Wang, Yujie and Voortman, Trudy and Noordam, Raymond and Frazier-Wood, Alexis and Scholz, Markus and Sonestedt, Emily and Akiyama, Masato and Dorajoo, Rajkumar and Zhou, Ang and Kilpeläinen, Tuomas O and Kleber, Marcus E and Crozier, Sarah R and Godfrey, Keith M and Lemaitre, Rozenn and Felix, Janine F and Shi, Yuan and Gupta, Preeti and Khor, Chiea-Chuen and Lehtimäki, Terho and Wang, Carol A and Tiesler, Carla M. T and Thiering, Elisabeth and Standl, Marie and Rzehak, Peter and Marouli, Eirini and He, Meian and Lecoeur, Cécile and Corella, Dolores and Lai, Chao-Qiang and Moreno, Luis A and Pitkänen, Niina and Boreham, Colin A and Zhang, Tao and Saw, Seang Mei and Ridker, Paul M and Graff, Mariaelisa and van Rooij, Frank J. A and Uitterlinden, Andre G and Hofman, Albert and van Heemst, Diana and Rosendaal, Frits R and de Mutsert, Renée and Burkhardt, Ralph and Schulz, Christina-Alexandra and Ericson, Ulrika and Kamatani, Yoichiro and Yuan, Jian-Min and Power, Chris and Hansen, Torben and Sørensen, Thorkild I. A and Tjønneland, Anne and Overvad, Kim and Delgado, Graciela and Cooper, Cyrus and Djousse, Luc and Rivadeneira, Fernando and Jameson, Karen and Zhao, Wanting and Liu, Jianjun and Lee, Nanette R and Raitakari, Olli and Kähönen, Mika and Viikari, Jorma and Grote, Veit and Langhendries, Jean-Paul and Koletzko, Berthold and Escribano, Joaquin and Verduci, Elvira and Dedoussis, George and Yu, Caizheng and Tham, Yih Chung and Lim, Blanche and Lim, Sing Hui and Froguel, Philippe and Balkau, Beverley and Fink, Nadia R and Vinding, Rebecca K and Sevelsted, Astrid and Bisgaard, Hans and Coltell, Oscar and Dallongeville, Jean and Gottrand, Frédéric and Pahkala, Katja and Niinikoski, Harri and Hyppönen, Elina and Pedersen, Oluf and März, Winfried and Inskip, Hazel and Jaddoe, Vincent W. V and Dennison, Elaine and Wong, Tien Yin and ... and BIRTH-GENE (BIG) Study Working Group
JAMA Network Open, ISSN 2574-3805, 09/2019, Volume 2, Issue 9, p. e1910915
Journal Article
International journal of obesity (2005), ISSN 0307-0565, 08/2019
It is unclear to what extent adherence to dietary guidelines may specifically affect visceral fat and liver fat. We aimed to study the association between the... 
Journal Article
Journal of thrombosis and haemostasis : JTH, ISSN 1538-7933, 07/2019
It is insufficiently understood if there is an association between diabetes and VT, and what the underlying mechanism would be. We aimed to study the... 
Journal Article
Journal Article