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1. Full Text Role of properdin in complement-mediated kidney diseases
by van Essen, MF and Ruben, JM and de Vries, APJ and van Kooten, C and Berger, S and van den Born, J and Gros, P and van den Heuvel, L and van de Kar, N and Seelen, M and de Vries, A and COMBAT Consortium and COMBAT consortium and the COMBAT consortium
NEPHROLOGY DIALYSIS TRANSPLANTATION, ISSN 0931-0509, 05/2019, Volume 34, Issue 5, pp. 742 - 750
As part of the innate immune system, the complement system is an important mechanism in our first line of defence, but it can also contribute to the onset of... 
CELLS | ACTIVATION | C3 glomerulopathy | NEPHRITIC FACTORS | TRANSPLANTATION | kidney | properdin | ALTERNATIVE PATHWAY | LECTIN PATHWAY | UROLOGY & NEPHROLOGY | DECAY-ACCELERATING FACTOR | complement | glomerulonephritis | MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS | GLOMERULAR DEPOSITION | BINDING
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2. Full Text Estimated GFR: time for a critical appraisal
by Porrini, Esteban and Ruggenenti, Piero and Luis-Lima, Sergio and Carrara, Fabiola and Jiménez, Alejandro and de Vries, Aiko P. J and Torres, Armando and Gaspari, Flavio and Remuzzi, Giuseppe
Nature Reviews Nephrology, ISSN 1759-5061, 03/2019, Volume 15, Issue 3, pp. 177 - 190
Since 1957, over 70 equations based on creatinine and/or cystatin C levels have been developed to estimate glomerular filtration rate (GFR). However, whether... 
GLOMERULAR-FILTRATION-RATE | SERUM CYSTATIN-C | RELATIVE PERFORMANCE | COCKCROFT-GAULT EQUATIONS | UROLOGY & NEPHROLOGY | PREDICTIVE PERFORMANCE | PLASMA-CLEARANCE | CHRONIC KIDNEY-DISEASE | CREATININE CLEARANCE | CKD-EPI EQUATION | RENAL-TRANSPLANT RECIPIENTS
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3. Full Text Reproducibility of native T-1 mapping for renal tissue characterization at 3T
by Dekkers, IA and Paiman, EHM and de Vries, APJ and Lamb, HJ
JOURNAL OF MAGNETIC RESONANCE IMAGING, ISSN 1053-1807, 02/2019, Volume 49, Issue 2, pp. 588 - 596
Background Advanced renal disease is characterized by adverse changes in renal structure; however, noninvasive techniques to diagnose and monitor these changes... 
ACUTE KIDNEY INJURY | MOLLI | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
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4. Full Text Associations between normal range albuminuria, renal function and cardiovascular function in a population-based imaging study
by Dekkers, Ilona A and de Mutsert, Renée and Rabelink, Ton J and Jukema, Johan W and de Roos, Albert and Rosendaal, Frits R and Lamb, Hildo J and de Vries, Aiko P.J
Atherosclerosis, ISSN 0021-9150, 05/2018, Volume 272, pp. 94 - 100
In patients with impaired renal function and macroalbuminuria, cardiovascular risk factors are highly prevalent, however, whether this is also present in the... 
Cardiovascular system | Albuminuria | Magnetic resonance imaging | Vascular stiffness | Glomerular filtration rate | NETHERLANDS EPIDEMIOLOGY | CARDIAC & CARDIOVASCULAR SYSTEMS | PULSE-WAVE VELOCITY | HEART | DISEASE | CYSTATIN-C | PERIPHERAL VASCULAR DISEASE | HEPATIC TRIGLYCERIDE CONTENT | DYSFUNCTION | Cardiac patients | Diagnostic imaging | Wave propagation
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5. Full Text Immunomonitoring of Tacrolimus in Healthy Volunteers: The First Step from PK- to PD-Based Therapeutic Drug Monitoring?
by Veld, AEI and Grievink, HW and Saghari, M and Stuurman, FE and de Kam, ML and de Vries, APJ and de Winter, BCM and Burggraaf, J and Cohen, AF and Moerland, M
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1422-0067, 10/2019, Volume 20, Issue 19, p. 4710
Therapeutic drug monitoring is routinely performed to maintain optimal tacrolimus concentrations in kidney transplant recipients. Nonetheless, toxicity and... 
immunomonitoring | LYMPHOCYTE | pharmacodynamics | tacrolimus | TRANSPLANT PATIENTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | immunosuppressive drugs | RECIPIENTS | CHEMISTRY, MULTIDISCIPLINARY | MOLECULES | ACUTE REJECTION | POPULATION PHARMACOKINETICS | transplantation | pharmacokinetics | T-CELL ACTIVATION | GRAFT-SURVIVAL | EXPRESSION | therapeutic drug monitoring
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6. Full Text H-1-MRS for the assessment of renal triglyceride content in humans at 3T: A primer and reproducibility study
by Dekkers, IA and de Heer, P and Bizino, MB and de Vries, APJ and Lamb, HJ
JOURNAL OF MAGNETIC RESONANCE IMAGING, ISSN 1053-1807, 08/2018, Volume 48, Issue 2, pp. 507 - 513
BackgroundRenal steatosis (fatty kidney) is a potential biomarker for obesity-related renal disease; however, noninvasive assessment of renal fat content... 
fatty kidney | reproducibility | BLAND | DIABETIC-NEPHROPATHY | proton magnetic resonance spectroscopy | CLINICAL MEASUREMENT | HUMAN KIDNEY | SPECTROSCOPY | renal triglyceride content | DISEASE | ADIPOSITY | ALTMAN ANALYSIS | PROTON MR | metabolic imaging | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
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7. Full Text Estimated GFR: time for a critical appraisal (vol 15, pg 177, 2018)
by Porrini, E and Ruggenenti, P and Luis-Lima, S and Carrara, F and Jimenez, A and de Vries, APJ and Torres, A and Gaspari, F and Remuzzi, G
NATURE REVIEWS NEPHROLOGY, ISSN 1759-5061, 02/2019, Volume 15, Issue 2, pp. 121 - 121
UROLOGY & NEPHROLOGY
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8. Full Text Association of Hepcidin-25 with survival after kidney transplantation
by Eisenga, Michele F and Dullaart, Robin P. F and Berger, Stefan P and Sloan, John H and de Vries, Aiko P. J and Bakker, Stephan J. L and Gaillard, Carlo A. J. M
European Journal of Clinical Investigation, ISSN 0014-2972, 12/2016, Volume 46, Issue 12, pp. 994 - 1001
Background Hepcidin is considered the master regulator of iron homoeostasis. Novel hepcidin antagonists have recently been introduced as potential treatment... 
hepcidin | renal transplantation | FERROPORTIN | graft failure | RECIPIENTS | GENERAL-POPULATION | MODULATES IRON-METABOLISM | CHRONIC DISEASE | SERUM HEPCIDIN | mortality | HEMODIALYSIS-PATIENTS | Determinants | ANEMIA | FERRITIN | MEDICINE, RESEARCH & EXPERIMENTAL | MEDICINE, GENERAL & INTERNAL | Kidney Failure, Chronic - surgery | Prognosis | Prospective Studies | Enzyme-Linked Immunosorbent Assay | Acute Kidney Injury - blood | Humans | Middle Aged | Mortality | Proportional Hazards Models | Hepcidins - blood | Linear Models | Survival Rate | Kidney Transplantation | Cause of Death | C-Reactive Protein - metabolism | Ferritins - blood | Kidney Failure, Chronic - blood | Cardiovascular Diseases - blood | Cardiovascular Diseases - mortality | Adult | Kidneys | Analysis | Ferritin | Hemoglobin | Organ transplant recipients | Transplantation | Immunoassay | Transplants & implants | Antagonists | Iron | Grafting | Proteins | Confidence intervals | Regression models | Failure analysis | Enzyme-linked immunosorbent assay | Statistical analysis | Anemia | Therapeutic applications | Health risks | Regression analysis | Survival | Glomerular filtration rate | Rejection | Grafts | Cardiovascular diseases | Health risk assessment | Hepcidin | Kidney transplantation | Original
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9. Full Text Long-term cardiovascular outcome of renal transplant recipients after early conversion to everolimus compared to calcineurin inhibition: results from the randomized controlled MECANO trial
by van Dijk, Marja and van Roon, Arie M and Said, M. Yusof and Bemelman, Frederike J and Homan van der Heide, Jaap J and de Fijter, Hans W and de Vries, Aiko P. J and Bakker, Stephan J. L and Sanders, Jan Stephan F
Transplant international, ISSN 0934-0874, 2018, Volume 31, Issue 12, pp. 1380 - 1390
Long-term data on cardiovascular (CV) outcome of renal transplant recipients (RTR) on mTOR-i (mammalian Target Of Rapamycin-inhibitors) are scarce. In a... 
immunosuppression | cardiovascular outcome | intima media thickness | kidney transplantation | INTIMA-MEDIA THICKNESS | MORTALITY | SURGERY | KIDNEY-TRANSPLANTATION | RISK | MAINTENANCE IMMUNOSUPPRESSION | CYCLOSPORINE | TRANSPLANTATION | Organ transplant recipients | Transplantation | Kidneys | Comparative analysis | Immunotherapy | Cardiac patients | TOR protein | Cyclosporins | Calcineurin | Mortality | Health risks | Rapamycin | Risk analysis | Patients | Survival | Risk factors | Randomization | Mathematical analysis | Risk assessment | Carotid artery | Cardiovascular diseases | Health risk assessment | Prednisolone | Kidney transplantation
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10. Diagnosis and treatment of C3 glomerulopathy in a center of expertise
by Koopman, J.J.E and Teng, Y.K.O and Boon, C.J.F and Van Den Heuvel, L.P and Rabelink, T.J and Van Kooten, C and De Vries, A.P.J
Netherlands Journal of Medicine, ISSN 0300-2977, 01/2019, Volume 77, Issue 1, pp. 10 - 18
C3 glomerulopathy is a rare renal disease that has been distinguished as a renal disease for about 10 years. It is caused by an excessive activation of the... 
Center of expertise | Membranoproliferative glomerulonephritis | glomerulonephritis | glomerulopathy | Dense deposit disease | ECULIZUMAB | VARIANTS | C3 glomerulopathy | NEPHRITIC FACTORS | MEDICINE, GENERAL & INTERNAL | dense deposit disease | membranoproliferative glomerulonephritis | ALTERNATIVE PATHWAY | DYSREGULATION | MONOCLONAL GAMMOPATHY | OUTCOMES | center of expertise | C3 glomerulonephritis
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11. Full Text Clinical trials for treatment of NODAT: Time to collaborate
by Sharif, Adnan and De Vries, Aiko P.J and Porrini, Esteban and Hecking, Manfred and Saemann, Marcus and European-New-Onset Diabet After and European–New-Onset Diabetes After Transplantation Working Group
Transplantation, ISSN 0041-1337, 08/2012, Volume 94, Issue 4, pp. e23 - e24
SURGERY | METFORMIN | MANAGEMENT | RENAL-TRANSPLANTATION | IMMUNOLOGY | RECIPIENTS | ONSET DIABETES-MELLITUS | TRANSPLANTATION | Hypoglycemic Agents - therapeutic use | Diabetes Mellitus - etiology | Clinical Trials as Topic | Humans | Diabetes Mellitus - drug therapy | Kidney Transplantation - adverse effects
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12. Full Text Physiological Approach to Assessment of Acid-Base Disturbances REPLY
by Berend, Kenrick and de Vries, Aiko P. J and Gans, Rijk O. B
New England Journal of Medicine, ISSN 0028-4793, 01/2015, Volume 372, Issue 2, pp. 195 - 195
ARTERIAL | BLOOD | MEDICINE, GENERAL & INTERNAL
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13. Full Text Physiological Approach to Assessment of Acid–Base Disturbances
by Berend, Kenrick and de Vries, Aiko P.J and Gans, Rijk O.B
The New England Journal of Medicine, ISSN 0028-4793, 10/2014, Volume 371, Issue 15, pp. 1434 - 1445
Acid–base homeostasis is fundamental for maintaining life. This article reviews a stepwise method for the physiological approach to evaluation of acid–base... 
DIAGNOSIS | STEWART | MEDICINE, GENERAL & INTERNAL | METABOLIC-ACIDOSIS | INTENSIVE-CARE-UNIT | DIABETIC-KETOACIDOSIS | DISORDERS | SERUM ANION GAP | RENAL TUBULAR-ACIDOSIS | CRITICALLY-ILL PATIENTS | PATHOPHYSIOLOGY | Acid-Base Imbalance - etiology | Homeostasis - physiology | Humans | Acid-Base Imbalance - physiopathology | Acid-Base Imbalance - diagnosis | Bicarbonates - metabolism | Reference Values | Oxygen - metabolism | Hydrogen-Ion Concentration | Adaptation (Physiology) | Analysis | Plasma | Pneumonia | Internal medicine | Hydrogen | Carbon dioxide | Homeostasis | Alcohol | Metabolism | Patients | Medicine | Acids | Drunkenness | Electrolytes | Physiology | Acid-base status
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14. Full Text Obesity-related glomerulopathy: Clinical and pathologic characteristics and pathogenesis
by D'Agati, Vivette D and Chagnac, Avry and De Vries, Aiko P.J and Levi, Moshe and Porrini, Esteban and Herman-Edelstein, Michal and Praga, Manuel
Nature Reviews Nephrology, ISSN 1759-5061, 08/2016, Volume 12, Issue 8, pp. 453 - 471
The prevalence of obesity-related glomerulopathy is increasing in parallel with the worldwide obesity epidemic. Glomerular hypertrophy and adaptive focal... 
URINARY ALBUMIN EXCRETION | SYMPATHETIC-NERVOUS-SYSTEM | LOW-BIRTH-WEIGHT | UROLOGY & NEPHROLOGY | BODY-MASS INDEX | RENAL LIPID-METABOLISM | X-RECEPTOR-ALPHA | CHRONIC KIDNEY-DISEASE | FOCAL SEGMENTAL GLOMERULOSCLEROSIS | ELEMENT-BINDING PROTEINS | BETA UP-REGULATION | Glomerulosclerosis, Focal Segmental - etiology | Kidney Diseases - pathology | Obesity - complications | Humans | Kidney Diseases - diagnosis | Obesity - therapy | Kidney Diseases - therapy | Obesity - physiopathology | Kidney Diseases - etiology | Kidney Glomerulus - pathology | Glomerulosclerosis, Focal Segmental - pathology | Obesity - metabolism | Glomerulonephritis | Obesity | Complications and side effects | Physiological aspects | Development and progression | Genetic aspects | Cellular signal transduction | Research | Risk factors
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