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1. Full Text Pre- and Perinatal Characteristics Associated with Apgar Scores in a Review and in a New Study of Dutch Twins
by Odintsova, Veronika V and Dolan, Conor V and van Beijsterveldt, Catharina E M and de Zeeuw, Eveline L and van Dongen, Jenny and Boomsma, Dorret I
Twin research and human genetics : the official journal of the International Society for Twin Studies, ISSN 1832-4274, 06/2019, p. 1
A literature review was carried out to identify pre and perinatal characteristics associated with variation in Apgar scores in population-based studies. The... 
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2. Full Text Physical activity and dietary intake in BMI discordant identical twins
: Physical Activity and Dietary Intake in Twins
by Doornweerd, Stieneke and IJzerman, Richard G and van der Eijk, Lotte and Neter, Judith E and van Dongen, Jenny and van der Ploeg, Hidde P and de Geus, Eco J
Obesity, ISSN 1930-7381, 06/2016, Volume 24, Issue 6, pp. 1349 - 1355
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3. Full Text The continuing value of twin studies in the omics era
by van Dongen, J and Slagboom, P.E and isma, H.H.M and Martin, N.G and Boomsma, D.I
Nature Reviews Genetics, ISSN 1471-0056, 2012, Volume 13, Issue 9, pp. 640 - 653
The classical twin study has been a powerful heuristic in biomedical, psychiatric and behavioural research for decades. Twin registries worldwide have... 
DISCORDANT MONOZYGOTIC TWINS | POPULATION-BASED TWIN | DNA METHYLATION | EPIGENETIC DIFFERENCES | GENETICS & HEREDITY | BIRTH-WEIGHT | LYMPHOBLASTOID CELL-LINES | GENETIC INFLUENCES | AUTISM SPECTRUM DISORDERS | BIPOLAR DISORDER | GENOME-WIDE ASSOCIATION | Metabolomics | Epigenomics | Genomics | Humans | Genetic Diseases, Inborn - genetics | Proteomics | Female | Male | Registries | Twin Studies as Topic | Longitudinal Studies | Phenotype | Heritability | Research | Genetic variation
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4. Full Text eFORGE: A Tool for Identifying Cell Type-Specific Signal in Epigenomic Data
by Breeze, Charles E and Paul, Dirk S and van Dongen, Jenny and Butcher, Lee M and Ambrose, John C and Barrett, James E and Lowe, Robert and Rakyan, Vardhman K and Iotchkova, Valentina and Frontini, Mattia and Downes, Kate and Ouwehand, Willem H and Laperle, Jonathan and Jacques, Pierre-ETienne and Bourque, Guillaume and Bergmann, Anke K and Siebert, Reiner and Vellenga, Edo and Saeed, Sadia and Matarese, Filomena and Martens, Joost H. A and Stunnenberg, Henik G and Teschendorff, Anew E and Herrero, Javier and Birney, Ewan and Dunham, Ian and Beck, Stephan
Cell reports, ISSN 2211-1247, 11/2016, Volume 17, Issue 8, pp. 2137 - 2150
Epigenome-wide association studies (EWAS) provide an alternative approach for studying human disease through consideration of non-genetic variants such as... 
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5. Full Text The evolutionary paradox and the missing heritability of schizophrenia
by van Dongen, J and Boomsma, D.I
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, ISSN 1552-4841, 2013, Volume 162, Issue 2, pp. 122 - 136
Schizophrenia is one of the most detrimental common psychiatric disorders, occurring at a prevalence of approximately 1%, and characterized by increased... 
genetics | schizophrenia | evolution | missing heritability | psychosis | Psychosis | Schizophrenia | Missing heritability | Evolution | Genetics | RHEUMATOID-ARTHRITIS | DNA METHYLATION | PHENOTYPIC PLASTICITY | PSYCHIATRY | HOMO-SAPIENS PAYS | 1ST-DEGREE RELATIVES | AUTISM SPECTRUM DISORDERS | GENETIC EPIDEMIOLOGY | NEGATIVE ASSOCIATION | GENETICS & HEREDITY | FLUCTUATING ASYMMETRY | MENTAL-ILLNESS | Biological Evolution | Genetic Variation | Schizophrenia - genetics | Epigenesis, Genetic | Humans | Selection, Genetic | Inheritance Patterns - genetics | Genetic research | Mortality | Analysis | Genomics
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6. Full Text Genetic and environmental influences interact with age and sex in shaping the human methylome
by van Dongen, Jenny and Nivard, Michel and Willemsen, Gonneke and Hottenga, Jouke Jan and Helmer, Quinta and Dolan, Conor and Ehli, Erik and Davies, Gareth and Iterson, M and Breeze, Charles E and Beck, Stephan and Suchiman, Eka and Jansen, R and Meurs, Joyce and Heijman, Bastiaan and Slagboom, Eline and Boomsma, Dorret and BIOS Consortium
Nature Communications, ISSN 2041-1723, 04/2016, Volume 7, Issue 1, p. 11115
textabstractThe methylome is subject to genetic and environmental effects. Their impact may depend on sex and age, resulting in sex-and age-related... 
LIPID-LOWERING DRUGS | DNA METHYLATION AGE | EPIGENETIC VARIATION | CPG ISLAND SHORES | PRENATAL FAMINE | MULTIDISCIPLINARY SCIENCES | BISPHENOL-A | DIET NETWORK | COMPLEX TRAITS | EPIGENOME-WIDE ASSOCIATION | MONOZYGOTIC TWINS | Age Factors | Twins, Monozygotic - genetics | Humans | Child, Preschool | Male | Gene-Environment Interaction | Twins, Dizygotic - genetics | Inheritance Patterns | DNA Methylation | Phenotype | Aging - genetics | Smoking - physiopathology | Adolescent | Sex Factors | CpG Islands | Adult | Female | Polymorphism, Single Nucleotide | Genome, Human
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7. Full Text The Adult Netherlands Twin Register: Twenty-five years of survey and biological data collection
by Willemsen, G and Vink, J.M and Abdellaoui, A and Braber, A. den and Beek, J.H.D.H. van and isma, H.H.M and Dongen, J. van and Ent, D. van 't and Geels, L.M and Lien, R. van and Ligthart, R.S.L and Kattenberg, M and Mbarek, H and Moor, M.H.M. de and Neijts, M and Pool, R and Stroo, N and Kluft, C and Suchiman, H.E.D and Slagboom, P.E and Geus, E.J.C. de and Boomsma, D.I
Twin Research and Human Genetics, ISSN 1832-4274, 2013, Volume 16, Issue 1, pp. 271 - 281
Over the past 25 years, the Adult Netherlands Twin Register (ANTR) has collected a wealth of information on physical and mental health, lifestyle, and... 
Family relationships | DNA | Analysis | Biobanks | Data processing | Twins | Registers of births, etc | longitudinal surveys | gene finding | twin family studies | biobank | ENVIRONMENT INTERACTION | LOCI | OBSTETRICS & GYNECOLOGY | ALCOHOL-USE | GENETIC VARIANCE | GENETICS & HEREDITY | OBSESSIVE-COMPULSIVE SYMPTOMS | DUTCH TWINS | MAJOR DEPRESSIVE DISORDER | SMOKING-BEHAVIOR | LIFE EVENTS | GENOME-WIDE ASSOCIATION | Twins - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Diseases in Twins - genetics | Humans | Netherlands - epidemiology | Male | Gene-Environment Interaction | Young Adult | Biological Specimen Banks | Adolescent | Adult | Biomedical Research | Female | Registries | Diseases in Twins - epidemiology | Longitudinal Studies
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8. Full Text Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology
by Ferreira, Manuel A and Vonk, Judith M and Baurecht, Hansjörg and Marenholz, Ingo and Tian, Chao and Hoffman, Joshua D and Helmer, Quinta and Tillander, Annika and Ullemar, Vilhelmina and van Dongen, Jenny and Lu, Yi and Rüschendorf, Franz and Esparza-Gordillo, Jorge and Medway, Chris W and Mountjoy, Edward and Burrows, Kimberley and Hummel, Oliver and Grosche, Sarah and Brumpton, Ben M and Witte, John S and Hottenga, Jouke-Jan and Willemsen, Gonneke and Zheng, Jie and Roíguez, Elke and Hotze, Melanie and Franke, Ane and Revez, Joana A and Beesley, Jonathan and Matheson, Melanie C and Dharmage, Shyamali C and Bain, Lisa M and Fritsche, Lars G and Gabrielsen, Maiken E and Balliu, Brunilda and Nielsen, Jonas B and Zhou, Wei and Hveem, Kristian and Langhammer, Arnulf and Holmen, Oddgeir L and Løset, Mari and Abecasis, Gonçalo R and Willer, Cristen J and Arnold, Aneas and Homuth, Georg and Schmidt, Carsten O and Thompson, Philip J and Martin, Nicholas G and Duffy, David L and Novak, Natalija and Schulz, Holger and Karrasch, Stefan and Gieger, Christian and Strauch, Konstantin and Melles, Ronald B and Hinds, David A and Hübner, Norbert and Weidinger, Stephan and Magnusson, Patrik K E and Jansen, Rick and Jorgenson, Eric and Lee, Young-Ae and Boomsma, Dorret I and Almqvist, Catarina and Karlsson, Robert and Koppelman, Gerard H and Paternoster, Lavinia and 23andMe Res Team and BIOS consortium and LifeLines Cohort Study and AAGC collaborators and 23andMe Research Team
Nature Genetics, ISSN 1061-4036, 12/2017, Volume 49, Issue 12, pp. 1752 - 1757
Asthma, hay fever (or allergic rhinitis) and eczema (or atopic dermatitis) often coexist in the same individuals, partly because of a shared genetic origin. To... 
RHINITIS | ATOPIC-DERMATITIS | VARIANTS | TRANSCRIPTOME | HUMAN-CELLS | GENETICS & HEREDITY | COHORT | LD SCORE REGRESSION | IDENTIFICATION | GENOME-WIDE ASSOCIATION | TWIN | Eczema - genetics | Genetic Predisposition to Disease - genetics | Phenotype | Rhinitis, Allergic, Seasonal - genetics | Humans | Risk Factors | Hypersensitivity - genetics | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Asthma - genetics | Genome-wide association studies | Genetic variation | Eczema | Genetic aspects | Health aspects | Hay-fever | Risk factors | Methods | Asthma | Hay | Disease | Transcription | Rhinitis | Genes | Risk sharing | Genomes | Dermatitis | Immunity | Genetic effects | Atopic dermatitis | Allergic rhinitis | DNA methylation | Skin diseases | Age | CpG islands | Health risks | Risk analysis | Gene expression | Allergies | Biological activity | Hay fever | Studies | Heritability | Methylation
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9. Full Text Prenatal Famine and Genetic Variation Are Independently and Additively Associated with DNA Methylation at Regulatory Loci within IGF2/H19
by Tobi, E.W and Slagboom, P.E and van Dongen, J and Kremer, D and Stein, A.D and Putter, H and Heijmans, B.T and Lumey, L.H
PLoS One, ISSN 1932-6203, 2012, Volume 7, Issue 5, p. e37933
Both the early environment and genetic variation may affect DNA methylation, which is one of the major molecular marks of the epigenome. The combined effect of... 
FOLIC-ACID USE | IGF-II LEVELS | INSULIN GENE | BIOLOGY | BIRTH-WEIGHT | COMMON | TANDEM REPEAT | EPIGENETIC EPIDEMIOLOGY | MASS-SPECTROMETRY | IMPRINTED GENES | FOR-GESTATIONAL-AGE | Humans | Middle Aged | Genetic Loci - genetics | Male | DNA Methylation - genetics | Prenatal Nutritional Physiological Phenomena - genetics | Regulatory Sequences, Nucleic Acid - genetics | Genomic Imprinting - genetics | Pregnancy | Insulin-Like Growth Factor II - genetics | Epigenesis, Genetic - genetics | Polymorphism, Single Nucleotide - genetics | Female | Starvation - genetics | Siblings | Pregnant women | Analysis | DNA | Genetic research | Genetic aspects | Single nucleotide polymorphisms | Methylation | Chromosomes | Famines | Health care | Haplotypes | Genes | Single-nucleotide polymorphism | Insulin-like growth factors | Epidemiology | Consortia | Famine | DNA methylation | Genetic factors | Insulin-like growth factor II | Bioinformatics | Public health | Deoxyribonucleic acid--DNA | Quantitative analysis | Obesity | Middle age | Exposure | Genetic diversity | Insulin | Loci | Studies | Tagging | Scientific imaging | Birth weight | Umbilical cord | Variation | Mass spectrometry | Deoxyribonucleic acid
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10. Full Text Blood lipids influence DNA methylation in circulating cells
by Dekkers, Koen F and van Iterson, Maarten and Slieker, Roderick C and Moed, Matthijs H and Bonder, Marc Jan and van Galen, Michiel and Mei, Hailiang and Zhernakova, Daria V and van den Berg, Leonard H and Deelen, Joris and van Dongen, Jenny and van Heemst, Diana and Hofman, Albert and Hottenga, Jouke J and van der Kallen, Carla J. H and Schalkwijk, Casper G and Stehouwer, Coen D. A and Tigchelaar, Ettje F and Uitterlinden, Ane G and Willemsen, Gonneke and Zhernakova, Alexana and Franke, Lude and t Hoen, Peter A. C and Jansen, Rick and van Meurs, Joyce and Boomsma, Dorret I and van Duijn, Cornelia M and van Greevenbroek, Marleen M. J and Veldink, Jan H and Wijmenga, Cisca and van Zwet, Erik W and Slagboom, P. Eline and Jukema, J. Wouter and Heijmans, Bastiaan T and BIOS Consortium
Genome Biology, ISSN 1465-6906, 06/2016, Volume 17, Issue 1, p. 138
Background: Cells can be primed by external stimuli to obtain a long-term epigenetic memory. We hypothesize that long-term exposure to elevated blood lipids... 
DNA methylation | Lipids | Mendelian randomization | Gene expression | SURVIVAL | SYSTEM | CHOLESTEROL | PATTERNS | TIME | PLASMA | CPT1A LOCUS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | EPIGENOME-WIDE ASSOCIATION | EXPOSURE | Nerve Tissue Proteins - blood | ATP Binding Cassette Transporter, Subfamily G, Member 1 - blood | Carnitine O-Palmitoyltransferase - genetics | Lipids - genetics | Epigenesis, Genetic | Humans | Middle Aged | Male | ATP Binding Cassette Transporter, Subfamily G, Member 1 - genetics | Lipids - blood | Oxidoreductases Acting on CH-CH Group Donors - blood | Aged, 80 and over | Adult | Cholesterol, LDL - blood | Female | Lipid Metabolism - genetics | Oxidoreductases Acting on CH-CH Group Donors - genetics | Carnitine O-Palmitoyltransferase - blood | Gene Expression Regulation - genetics | DNA Methylation - genetics | Cholesterol, HDL - genetics | Nerve Tissue Proteins - genetics | Cholesterol, LDL - genetics | Sterol Regulatory Element Binding Protein 1 - genetics | Sterol Regulatory Element Binding Protein 1 - blood | Adolescent | Triglycerides - blood | Cholesterol, HDL - blood | CpG Islands - genetics | Aged | Triglycerides - genetics | Genome, Human | Lipoproteins (low density) | Triglycerides | Genomes | Ribonucleic acid--RNA | Blood | Cholesterol | Studies | Consortia | Genotype & phenotype | Pleiotropy | External stimuli | Arteriosclerosis | Atherosclerosis | Quality control | Standard deviation | Lipid metabolism | Methylation | Bioinformatics | Lipoproteins (high density) | Deoxyribonucleic acid--DNA | CpG islands
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