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index medicus (39) 39
humans (37) 37
dermatology (32) 32
vitiligo (27) 27
male (18) 18
adult (16) 16
female (16) 16
melanoma (13) 13
middle aged (13) 13
vitiligo - pathology (12) 12
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skin (11) 11
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vitiligo - therapy (7) 7
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generalized vitiligo (5) 5
integumentary system (5) 5
medicine and health sciences (5) 5
melanocyte (5) 5
melanoma - immunology (5) 5
regulatory t-cells (5) 5
severity of illness index (5) 5
susceptibility loci (5) 5
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article (4) 4
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indoleamine 2,3-dioxygenase (4) 4
medical colleges (4) 4
prognosis (4) 4
psoriasis (4) 4
segmental vitiligo (4) 4
skin neoplasms - immunology (4) 4
skin neoplasms - pathology (4) 4
skin pigmentation (4) 4
t cells (4) 4
treatment outcome (4) 4
young adult (4) 4
age (3) 3
biomarkers - blood (3) 3
body surface area (3) 3
cancer (3) 3
care and treatment (3) 3
cd8-positive t-lymphocytes - immunology (3) 3
cells (3) 3
cosmin (3) 3
disease progression (3) 3
disease-activity (3) 3
double-blind (3) 3
flow cytometry (3) 3
genetic aspects (3) 3
halo nevi (3) 3
human melanocytes (3) 3
immune response (3) 3
immunology (3) 3
inflammation (3) 3
lymphocytes (3) 3
melanoma - pathology (3) 3
observer variation (3) 3
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prospective studies (3) 3
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quality-of-life (3) 3
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research (3) 3
review (3) 3
risk factors (3) 3
sensitivity and specificity (3) 3
severity (3) 3
skin - pathology (3) 3
surgery (3) 3
surgical treatment (3) 3
usage (3) 3
vitiligo - blood (3) 3
vitiligo - drug therapy (3) 3
vitiligo - metabolism (3) 3
abridged index medicus (2) 2
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adolescent (2) 2
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alopecia-areata (2) 2
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autoimmune diseases (2) 2
autoimmune vitiligo (2) 2
autoimmune-diseases (2) 2
biochemistry, genetics and molecular biology (2) 2
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1. Full Text IL‐17A is not a treatment target in progressive vitiligo
by Speeckaert, Reinhart and Mylle, Sofie and Geel, Nanja
Pigment Cell & Melanoma Research, ISSN 1755-1471, 11/2019, Volume 32, Issue 6, pp. 842 - 847
Multiple reports confirm elevated circulating IL‐17 levels and increased numbers of Th17 lymphocytes in patients with non‐segmental vitiligo. Additionally,... 
vitiligo | IL‐17 | Th17 pathway | Vitiligo | Cytokines | Lymphocytes | Medical treatment | Helper cells | Skin | Lymphocytes T | Cell differentiation | Chemokines
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2. Full Text Early-onset autoimmune vitiligo associated with an enhancer variant haplotype that upregulates class II HLA expression
by Jin, Ying and Roberts, Genevieve H. L and Ferrara, Tracey M and Ben, Songtao and van Geel, Nanja and Wolkerstorfer, Albert and Ezzedine, Khaled and Siebert, Janet and Neff, Charles P and Palmer, Brent E and Santorico, Stephanie A and Spritz, Richard A
Nature communications, ISSN 2041-1723, 2019, Volume 10, Issue 1, pp. 391 - 10
Vitiligo is an autoimmune disease in which melanocyte destruction causes skin depigmentation, with 49 loci known from previous GWAS. Aiming to define vitiligo... 
DISEASES | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY LOCI | DNA ELEMENTS | RISK | PREVALENCE | GENOME-WIDE ASSOCIATION | Haplotypes | Dendritic cells | Health risks | mRNA | Gene expression | Loci | Subgroups | Proteins | Monocytes | Vitiligo | Enhancers | Major histocompatibility complex | Histocompatibility antigen HLA | Variation | Autoimmune diseases | Age
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3. Full Text Learning From Success and Failure: Biologics for Non-approved Skin Diseases
by Speeckaert, R and Lambert, J and van Geel, N
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 08/2019, Volume 10, p. 1918
The impressive potential of biologics has been demonstrated in psoriasis, hidradenitis suppurativa, and urticaria. Numerous biologicals are entering the field... 
CD20 | biologics | TNF-alpha | IL-1 | IgE | SWEET SYNDROME | LUPUS-ERYTHEMATOSUS | IMMUNOLOGY | IL-12 | IL-23 | RECEPTOR ANTAGONIST | IGE AUTOANTIBODIES | ALOPECIA-AREATA | PYODERMA-GANGRENOSUM | DOUBLE-BLIND | CASE SERIES | HIDRADENITIS SUPPURATIVA | off-label | Omalizumab | Skin diseases | Usage | Care and treatment | Biological products | Risk factors | Psoriasis | Drug therapy | TNF-α
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4. Full Text Early-onset autoimmune vitiligo associated with an enhancer variant haplotype that upregulates class II HLA expression
by Jin, Ying and Roberts, Genevieve H. L and Ferrara, Tracey M and Ben, Songtao and van Geel, Nanja and Wolkerstorfer, Albert and Ezzedine, Khaled and Siebert, Janet and Neff, Charles P and Palmer, Brent E and Santorico, Stephanie A and Spritz, Richard A
Nature Communications, ISSN 2041-1723, 2019, Volume 10, Issue 1
Vitiligo is an autoimmune disease in which melanocyte destruction causes skin depigmentation, with 49 loci known from previous GWAS. Aiming to define vitiligo... 
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5. Full Text Vitiligo : Medical and Surgical Managmement
by Gupta, Somesh and Olsson, Mats J and Parsad, Davinder and Lim, Henry W and Geel, Nanja van and Pandya, Amit G
04/2018, ISBN 9781118937419, 536
Vitiligo
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6. Full Text Validation study of the Vitiligo Extent Score-plus (VESplus)
by van Geel, Nanja and Wolkerstorfer, Albert and Lommerts, Janny E and Ezzedine, Khaled and Eleftheriadou, Viktoria and Hamzavi, Iltefat and Harris, John and Picardo, Mauro and Taieb, Alain and Prinsen, Cecilia Ac and Bekkenk, Marcel and Speeckaert, Reinhart
Journal of the American Academy of Dermatology, ISSN 0190-9622, 05/2018, Volume 78, Issue 5, pp. 1013 - 1015
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7. Full Text Standardizing serial photography for assessing and monitoring vitiligo: a core set of international recommendations for essential clinical and technical specifications
by van Geel, Nanja and Hamzavi, Iltefat and Kohli, Indermeet and Wolkerstorfer, Albert and Lim, Henry W and Bae, Jung Min and Lui, Harvey and Harris, John E and Pandya, Amit G and Guan, Steven Thng Tien and Abdallah, Marwa and Esmat, Samia and Seneschal, Julien and Speeckaert, Reinhart and Grine, Lynda and Kang, Hee Young and Raboobee, Noufal and Xiang, Leihong Flora and Bekkenk, Marcel and Picardo, Mauro and Taieb, Alain
Journal of the American Academy of Dermatology, ISSN 0190-9622, 10/2019
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8. Full Text Measuring the Impact of Vitiligo: Behind the White Spots
by Speeckaert, Reinhart and Lambert, Jo and van Geel, Nanja
Journal of Investigative Dermatology, ISSN 0022-202X, 01/2016, Volume 136, Issue 1, pp. 6 - 7
The impact of vitiligo is generally believed to be underestimated. Salzes et al. propose a questionnaire to measure the actual burden of vitiligo. Using a... 
Sickness Impact Profile | Vitiligo - psychology | Humans | Female | Male | Surveys and Questionnaires | Quality of Life - psychology | INSTRUMENT | PSORIASIS | DERMATOLOGY
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9. Targeting the IL-23/IL-17 Pathway in Psoriasis: the Search for the Good, the Bad and the Ugly
by Mylle, Sofie and Grine, Lynda and Speeckaert, Reinhart and Lambert, Jo L.W and van Geel, Nanja
American Journal of Clinical Dermatology, ISSN 1175-0561, 10/2018, Volume 19, Issue 5, pp. 625 - 637
New promising treatments have been developed for psoriasis that target different parts of the interleukin (IL)-23/IL-17 pathway. This approach is believed to... 
CONTROLLED-TRIAL | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | TUMOR-NECROSIS-FACTOR | DUAL INHIBITION | IFN-GAMMA | SEVERE PLAQUE PSORIASIS | ARTHRITIS PATIENTS | HOST-DEFENSE | EPIDERMAL HYPERPLASIA | T-CELLS | DERMATOLOGY
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10. Full Text The Vitiligo Extent Score (VES) and the VESplus are responsive instruments to assess global and regional treatment response in patients with vitiligo
by van Geel, Nanja and Bekkenk, Marcel and Lommerts, Janny E and Ezzedine, Khaled and Harris, John and Hamzavi, Iltefat and Eleftheriadou, Viktoria and Picardo, Mauro and Taieb, Alain and Prinsen, Cecilia A. C and Wolkerstorfer, Albert and Speeckaert, Reinhart
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2018, Volume 79, Issue 2, pp. 369 - 371
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11. Full Text Vitiligo
by Ezzedine, Khaled, Dr and Eleftheriadou, Viktoria, PhD and Whitton, Maxine, BA Hons and van Geel, Nanja, PhD
Lancet, The, ISSN 0140-6736, 2015, Volume 386, Issue 9988, pp. 74 - 84
Summary Vitiligo, an acquired pigmentary disorder of unknown origin, is the most frequent cause of depigmentation worldwide, with an estimated prevalence of... 
Internal Medicine | CHILDHOOD VITILIGO | IMMUNE-RESPONSE | MEDICINE, GENERAL & INTERNAL | DEPIGMENTATION THERAPY | GENERALIZED VITILIGO | INCREASED SENSITIVITY | SUSCEPTIBILITY LOCI | QUALITY-OF-LIFE | KOEBNERS PHENOMENON | HUMAN MELANOCYTES | T-CELLS | Phototherapy - methods | Vitiligo - diagnosis | Vitiligo - therapy | Vitiligo - psychology | Humans | Vitiligo - immunology | Dermatologic Agents - therapeutic use | Vitiligo - epidemiology | Mental Disorders - etiology | Skin | Vitiligo | Pathogenesis | Classification | Epidemiology | Patients | Age
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12. Full Text Development and validation of a patient-reported outcome measure in vitiligo: The Self Assessment Vitiligo Extent Score (SA-VES)
by van Geel, Nanja and Lommerts, Janny E and Bekkenk, Marcel W and Prinsen, Cecilia A.C and Eleftheriadou, Viktoria and Taieb, Alain and Picardo, Mauro and Ezzedine, Khaled and Wolkerstorfer, Albert and Speeckaert, Reinhart
Journal of the American Academy of Dermatology, ISSN 0190-9622, 03/2017, Volume 76, Issue 3, pp. 464 - 471
Background The Vitiligo Extent Score (VES) has recently been introduced as a physicians' score for the clinical assessment of the extent of vitiligo, but a... 
severity | patient-reported outcomes | Dermatology | outcome measurement | vitiligo | body surface area
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13. Vitiligo: An Update on Pathophysiology and Treatment Options
by Speeckaert, Reinhart and van Geel, Nanja
American journal of clinical dermatology, 12/2017, Volume 18, Issue 6, p. 733
The pathophysiology of vitiligo is becoming increasingly clarified. In non-segmental vitiligo, early factors include activation of innate immunity,... 
Lasers, Excimer | Vitiligo - therapy | Photosensitizing Agents - therapeutic use | Humans | Immunosuppressive Agents - therapeutic use | Skin Pigmentation | Combined Modality Therapy | Plant Extracts - therapeutic use | Vitiligo - physiopathology | Phototherapy
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14. Full Text Koebner's phenomenon in vitiligo: European position paper
by van Geel, Nanja and Speeckaert, Reinhart and Taieb, Alain and Picardo, Mauro and Böhm, Markus and Gawkrodger, David J and Schallreuter, Karin and Bennett, Dorothy C and van der Veen, Wietze and Whitton, Maxine and Moretti, Silvia and Westerhof, Wiete and Ezzedine, Khaled and Gauthier, Yvon and VETF Members and VETF members
Pigment Cell and Melanoma Research, ISSN 1755-1471, 06/2011, Volume 24, Issue 3, pp. 564 - 573
P>Koebner's phenomenon (KP) has been observed in a number of skin diseases, including vitiligo. Its clinical significance in vitiligo with respect to disease... 
Vitiligo | Pathogenesis | Koebner's phenomenon | Melanocytorrhagy | Isomorphic response | Review | Trauma | trauma | DENDRITIC CELLS | vitiligo | HUMAN MELANOCYTES | isomorphic response | DISEASE-ACTIVITY | REPIGMENTATION | CELL BIOLOGY | DERMATOLOGY | pathogenesis | IN-VITRO | GENERALIZED VITILIGO | melanocytorrhagy | review | SKIN | T-CELLS | PSORIASIS | Vitiligo - therapy | Animals | Vitiligo - pathology | Humans | Chronic Disease | Vitiligo - metabolism | Vitiligo - physiopathology | Skin diseases
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15. Full Text Validation of a physician global assessment tool for vitiligo extent: Results of an international vitiligo expert meeting
by van Geel, Nanja and Wolkerstorfer, Albert and Ezzedine, Khaled and Pandya, Amit G and Bekkenk, Marcel and Grine, Lynda and van Belle, Sarah and Lommerts, Janny E and Hamzavi, Iltefat and Harris, John E and Eleftheriadou, Viktoria and Esmat, Samia and Kang, Hee Young and Kumarasinghe, Prasad and Lan, Cheng-Che E and Parsad, Davinder and Raboobee, Noufal and Flora Xiang, Leihong and Suzuki, Tamio and Prinsen, Cecilia A and Taieb, Alain and Picardo, Mauro and Speeckaert, Reinhart and Anbar, Tag and Anbar, Mohamed and Benzekri, Laïla and Böhm, Markus and Castro, Caïo and Cestari, Tania and Gauthier, Yvon and Gnarra, Maria and Hinojosa, Jorge and Jung, Min Bae and Katayama, Ichiro and Kim, Ki-Ho and Eric Lan, Cheng-Che and Lee, Seung-Chung and le Poole, Caroline and Lim, Henry and Moretti, Silvia and Seneschal, Julien and Spritz, Richard and Xiang, Flora
Pigment Cell and Melanoma Research, ISSN 1755-1471, 2019, Volume 32, Issue 5, pp. 728 - 733
Currently, vitiligo lacks a validated Physician Global Assessment (PGA) for disease extent. This PGA can be used to stratify and interpret the numeric scores... 
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16. Vitiligo: An Update on Pathophysiology and Treatment Options
by Speeckaert, Reinhart and van Geel, Nanja
American Journal of Clinical Dermatology, ISSN 1175-0561, 12/2017, Volume 18, Issue 6, pp. 733 - 744
The pathophysiology of vitiligo is becoming increasingly clarified. In non-segmental vitiligo, early factors include activation of innate immunity,... 
NARROW-BAND-UVB | GENERALIZED VITILIGO | DOUBLE-BLIND | SUSCEPTIBILITY LOCI | TERM-FOLLOW-UP | TOPICAL TACROLIMUS | TACROLIMUS OINTMENT | NON-SEGMENTAL VITILIGO | DISEASE-ACTIVITY | B PHOTOTHERAPY | DERMATOLOGY
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17. Full Text Systemic immune changes associated with adjuvant interferon-α2b-therapy in stage III melanoma patients: Failure at the effector phase?
by Chevolet, Ines and Schreuer, Max and Speeckaert, Reinhart and Neyns, Bart and Hoorens, Isabelle and Van Geel, Nanja and Krüse, Vibeke and Hennart, Benjamin and Allorge, Delphine and Van Gele, Mireille and Brochez, Lieve
Melanoma Research, ISSN 0960-8931, 07/2015, Volume 25, Issue 4, pp. 357 - 361
Interferon-α (IFN-α) is the only approved adjuvant treatment for high-risk melanoma patients in Europe, but the impact on overall survival is low. Although it... 
melanoma | negative feedback mechanism | indoleamine 2,3-dioxygenase | programmed-death ligand-1 | adjuvant interferon-α | Indoleamine-Pyrrole 2,3,-Dioxygenase - biosynthesis | T-Lymphocytes, Cytotoxic - immunology | Indoleamine-Pyrrole 2,3,-Dioxygenase - blood | Skin Neoplasms - drug therapy | Skin Neoplasms - immunology | Dendritic Cells - immunology | Europe | Humans | Middle Aged | Interferon-alpha - therapeutic use | Male | CTLA-4 Antigen - biosynthesis | Indoleamine-Pyrrole 2,3,-Dioxygenase - immunology | T-Lymphocytes, Regulatory - immunology | Flow Cytometry | Melanoma - immunology | Myeloid Cells - immunology | B7-H1 Antigen - biosynthesis | Leukocytes, Mononuclear - immunology | Melanoma - drug therapy | Adult | Female | Aged | Neoplasm Staging
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18. Targeting the IL-23/IL-17 Pathway in Psoriasis: the Search for the Good, the Bad and the Ugly
by Mylle, Sofie and Grine, Lynda and Speeckaert, Reinhart and Lambert, Jo L W and van Geel, Nanja
American journal of clinical dermatology, 10/2018, Volume 19, Issue 5, p. 625
New promising treatments have been developed for psoriasis that target different parts of the interleukin (IL)-23/IL-17 pathway. This approach is believed to... 
Psoriasis - immunology | Severity of Illness Index | Psoriasis - drug therapy | Humans | Immunosuppressive Agents - therapeutic use | Psoriasis - diagnosis | Receptors, Interleukin-17 - immunology | Interleukin-17 - immunology | Treatment Outcome | Receptors, Interleukin-17 - antagonists & inhibitors | Molecular Targeted Therapy | Interleukin-23 - immunology | Patient Selection | Interleukin-17 - metabolism | Signal Transduction - immunology | Interleukin-23 - metabolism | Interleukin-17 - antagonists & inhibitors | Signal Transduction - drug effects | Interleukin-23 - antagonists & inhibitors | Receptors, Interleukin-17 - metabolism | Immunosuppressive Agents - pharmacology
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19. Evaluation of commercially available ELISA assays as a tool for monitoring and managing pemphigus patients: A prospective study
by Bracke, Stefanie and Speeckaert, Reinhart and Van Geel, Nanja and De Bacquer, Dirk and Lambert, Jo
European Journal of Dermatology, ISSN 1167-1122, 01/2013, Volume 23, Issue 1, pp. 33 - 39
Background: Pemphigus is a potentially life-threatening auto-immune blistering disease and consequently it is important to monitor disease activity.... 
Dsg1 | Pemphigus vulgaris | Dsg3 | ELISA | Pemphigus foliaceus | AUTOANTIBODIES | ANTIBODIES | pemphigus foliaceus | PHAGE DISPLAY | RECOMBINANT DESMOGLEINS | DERMATOLOGY | pemphigus vulgaris | DISEASE | VULGARIS | CLINICAL PHENOTYPE | Severity of Illness Index | Desmoglein 3 - immunology | Predictive Value of Tests | Confidence Intervals | Prospective Studies | Enzyme-Linked Immunosorbent Assay | Immunoglobulin G - blood | Autoantibodies - blood | Humans | Middle Aged | Desmoglein 1 - immunology | Male | Time Factors | Adult | Female | Pemphigus - immunology | ROC Curve | Aged | Longitudinal Studies
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20. Full Text Clinical Significance of Serum Soluble CD Molecules to Assess Disease Activity in Vitiligo
by Speeckaert, Reinhart and Lambert, Jo and van Geel, Nanja
JAMA Dermatology, ISSN 2168-6068, 11/2016, Volume 152, Issue 11, pp. 1194 - 1200
IMPORTANCE: It is difficult to determine disease activity in vitiligo owing to the absence of inflammatory signs, such as erythema or scaling. A biomarker that... 
GAMMA | CXCL10 | CELLS | ACTIVATION | SKIN | EXPRESSION | DERMATOLOGY | Predictive Value of Tests | Vitiligo - diagnosis | Prospective Studies | Cross-Sectional Studies | Interleukin-2 Receptor alpha Subunit - blood | CD40 Ligand - blood | Humans | Middle Aged | Hospitals, University | Male | Biomarkers - blood | Tumor Necrosis Factor Receptor Superfamily, Member 7 - blood | Disease Progression | Vitiligo - blood | Sensitivity and Specificity | Adult | Female | Vitiligo | Usage | Interleukin-2 | Development and progression | Diagnosis | Research | Biological markers
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