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1. Full Text Letter by Pirson et al Regarding Article, “Results From DEFUSE 3 Good Collaterals Are Associated With Reduced Ischemic Core Growth but Not Neurologic Outcome”
by Pirson, F. Anne V and van Zwam, Wim H and van Oostenbrugge, Robert J and on behalf of MR CLEAN LATE executive committee
Stroke, ISSN 0039-2499, 06/2019, Volume 50, Issue 6, pp. e164 - e164
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2. Full Text Quantifying blood-brain barrier leakage in small vessel disease: Review and consensus recommendations
by Thrippleton, Michael J and Backes, Walter H and Sourbron, Steven and Ingrisch, Michael and van Osch, Matthias J.P and Dichgans, Martin and Fazekas, Franz and Ropele, Stefan and Frayne, Richard and van Oostenbrugge, Robert J and Smith, Eric E and Wardlaw, Joanna M
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 06/2019, Volume 15, Issue 6, pp. 840 - 858
Cerebral small vessel disease (cSVD) comprises pathological processes of the small vessels in the brain that may manifest clinically as stroke, cognitive... 
DCE-MRI | Blood-brain barrier | MRI | Endothelial dysfunction | Permeability | Cerebral small vessel disease | Dementia | Medicine, Experimental | Medical research | Neurosciences | Endothelium
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3. Full Text Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials
by Goyal, Mayank, Prof and Menon, Bijoy K, MD and van Zwam, Wim H, MD and Dippel, Diederik W J, Prof and Mitchell, Peter J, Prof and Demchuk, Andrew M, Prof and Dávalos, Antoni, Prof and Majoie, Charles B L M, Prof and van der Lugt, Aad, Prof and de Miquel, Maria A, MD and Donnan, Geoffrey A, Prof and Roos, Yvo B W E M, Prof and Bonafe, Alain, Prof and Jahan, Reza, MD and Diener, Hans-Christoph, Prof and van den Berg, Lucie A, MD and Levy, Elad I, Prof and Berkhemer, Olvert A, MD and Pereira, Vitor M, MD and Rempel, Jeremy, MD and Millán, Mònica, MD and Davis, Stephen M, Prof and Roy, Daniel, Prof and Thornton, John, MD and Román, Luis San, MD and Ribó, Marc, MD and Beumer, Debbie, MD and Stouch, Bruce, Prof and Brown, Scott, PhD and Campbell, Bruce C V, MD and van Oostenbrugge, Robert J, Prof and Saver, Jeffrey L, Prof and Hill, Michael D, Prof and Jovin, Tudor G, Dr and HERMES collaborators
Lancet, The, ISSN 0140-6736, 2016, Volume 387, Issue 10029, pp. 1723 - 1731
Summary Background In 2015, five randomised trials showed efficacy of endovascular thrombectomy over standard medical care in patients with acute ischaemic... 
Internal Medicine | Brain Ischemia - complications | Brain Ischemia - therapy | Humans | Middle Aged | Male | Treatment Outcome | Tissue Plasminogen Activator - therapeutic use | Randomized Controlled Trials as Topic | Stroke - etiology | Endovascular Procedures - methods | Fibrinolytic Agents - therapeutic use | Intracranial Hemorrhages - chemically induced | Thrombectomy - methods | Aged, 80 and over | Female | Aged | Odds Ratio | Stroke - therapy | Stroke (Disease) | Neurosciences | Ischemia | Analysis | Studies | Stroke | Clinical medicine | Medical treatment | Meta-analysis | Blood clots
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4. Full Text A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke
by Berkhemer, Olvert A and Fransen, Puck S.S and Beumer, Debbie and van den Berg, Lucie A and van den Berg, René and van den Berg, Jan S.P and Lingsma, Hester F and Yoo, Albert J and Schonewille, Wouter J and Vos, Jan Albert and Nederkoorn, Paul J and Wermer, Marieke J.H and van Walderveen, Marianne A.A and Staals, Julie and Hofmeijer, Jeannette and van Oostayen, Jacques A and Lycklama à Nijeholt, Geert J and Boiten, Jelis and Brouwer, Patrick A and Emmer, Bart J and de Bruijn, Sebastiaan F and van Dijk, Lukas C and van Dijk, Ewoud J and Kappelle, L. Jaap and Lo, Rob H and de Vries, Joost and de Kort, Paul L.M and van Rooij, Willem Jan J and van Hasselt, Boudewijn A.A.M and Aerden, Leo A.M and Dallinga, René J and Visser, Marieke C and Bot, Joseph C.J and Vroomen, Patrick C and Eshghi, Omid and Schreuder, Tobien H.C.M.L and Heijboer, Roel J.J and Keizer, Koos and Tielbeek, Alexander V and den Hertog, Heleen M and Gerrits, Dick G and van den Berg-Vos, Renske M and Karas, Giorgos B and Steyerberg, Ewout W and Flach, H. Zwenneke and Marquering, Henk A and Sprengers, Marieke E.S and Jenniskens, Sjoerd F.M and Beenen, Ludo F.M and Koudstaal, Peter J and van Zwam, Wim H and Roos, Yvo B.W.E.M and van der Lugt, Aad and van Oostenbrugge, Robert J and Majoie, Charles B.L.M and Dippel, Diederik W.J and MR CLEAN Investigators
The New England Journal of Medicine, ISSN 0028-4793, 01/2015, Volume 372, Issue 1, pp. 11 - 20
In patients with acute ischemic stroke due to a proximal intracranial arterial occlusion, intraarterial treatment (with retrievable stents in 82% of patients)... 
MEDICINE, GENERAL & INTERNAL | CEREBRAL INFARCT | THERAPY | SCORE | ENDOVASCULAR TREATMENT | RECANALIZATION | OCCLUSIONS | Single-Blind Method | Acute Disease | Urokinase-Type Plasminogen Activator - therapeutic use | Catheterization | Brain Ischemia - therapy | Humans | Middle Aged | Logistic Models | Male | Combined Modality Therapy | Stroke - drug therapy | Tissue Plasminogen Activator - therapeutic use | Brain Ischemia - drug therapy | Fibrinolytic Agents - therapeutic use | Aged, 80 and over | Adult | Female | Aged | Odds Ratio | Mechanical Thrombolysis | Stroke - therapy | Stroke (Disease) | Care and treatment | Usage | Arterial catheterization | Cardiac patients | Health aspects | Risk factors | Stroke | Intravenous administration | Medical imaging | Ischemia | Cerebral blood flow | Medical treatment | Implants | Clinical trials | Hemorrhage | Patients | Veins & arteries
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5. Full Text Magnesium for aneurysmal subarachnoid haemorrhage (MASH-2): a randomised placebo-controlled trial
by Mees, Sanne M Dorhout, MD and Algra, Ale, Prof and Vandertop, W Peter, Prof and van Kooten, Fop, MD and Kuijsten, Hans AJM, MD and Boiten, Jelis, MD and van Oostenbrugge, Robert J, Prof and Salman, Rustam Al-Shahi, PhD and Lavados, Pablo M, MD and Rinkel, Gabriel JE, Prof and van den Bergh, Walter M, MD and MASH-2 Study Group
Lancet, The, ISSN 0140-6736, 2012, Volume 380, Issue 9836, pp. 44 - 49
Summary Background Magnesium sulphate is a neuroprotective agent that might improve outcome after aneurysmal subarachnoid haemorrhage by reducing the... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | VASOSPASM | THERAPY | AGREEMENT | SULFATE | DELAYED CEREBRAL-ISCHEMIA | Magnesium Sulfate - administration & dosage | Humans | Middle Aged | Male | Treatment Outcome | Young Adult | Pilot Projects | Adolescent | Adult | Female | Aged | Infusions, Intravenous | Neuroprotective Agents - administration & dosage | Subarachnoid Hemorrhage - drug therapy | Physiological aspects | Placebos | Development and progression | Health aspects | Hemorrhage | Magnesium in the body | Aneurysms | Fatalities | Hospitals | Medical treatment
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6. Full Text Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis
by Saver, Jeffrey L and Goyal, Mayank and van der Lugt, Aad and Menon, Bijoy K and Majoie, Charles B. L. M and Dippel, Diederik W and Campbell, Bruce C and Nogueira, Raul G and Demchuk, Andrew M and Tomasello, Alejandro and Cardona, Pere and Devlin, Thomas G and Frei, Donald F and du Mesnil de Rochemont, Richard and Berkhemer, Olvert A and Jovin, Tudor G and Siddiqui, Adnan H and van Zwam, Wim H and Davis, Stephen M and Castaño, Carlos and Sapkota, Biggya L and Fransen, Puck S and Molina, Carlos and van Oostenbrugge, Robert J and Chamorro, Ángel and Lingsma, Hester and Silver, Frank L and Donnan, Geoffrey A and Shuaib, Ashfaq and Brown, Scott and Stouch, Bruce and Mitchell, Peter J and Davalos, Antoni and Roos, Yvo B. W. E. M and Hill, Michael D and HERMES Collaborators and for the HERMES Collaborators
JAMA, ISSN 0098-7484, 09/2016, Volume 316, Issue 12, pp. 1279 - 1289
IMPORTANCE: Endovascular thrombectomy with second-generation devices is beneficial for patients with ischemic stroke due to intracranial large-vessel... 
TRIAL | MEDICINE, GENERAL & INTERNAL | MANAGEMENT | THERAPY | TISSUE-PLASMINOGEN ACTIVATOR | REPERFUSION | ASSOCIATION | BRAIN | ONSET | Brain Ischemia | Time-to-Treatment | Humans | Male | Treatment Outcome | Intracranial Hemorrhages | Randomized Controlled Trials as Topic | Endovascular Procedures - methods | Reperfusion | Thrombectomy - methods | Female | Aged | Odds Ratio | Stents | Stroke - therapy | Stroke (Disease) | Care and treatment | Patients | Health aspects | Patient outcomes | Endovascular stents | Stroke | Vascular surgery | Meta-analysis
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7. Full Text Letter by Pirson et al Regarding Article, "Results From DEFUSE 3 Good Collaterals Are Associated With Reduced Ischemic Core Growth but Not Neurologic Outcome"
by Pirson, F Anne V and van Zwam, Wim H and van Oostenbrugge, Robert J
Stroke, 06/2019, Volume 50, Issue 6, p. e164
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8. Full Text Unraveling the Relationship between Motor Symptoms, Affective States and Contextual Factors in Parkinson's Disease: A Feasibility Study of the Experience Sampling Method
by Broen, Martijn P. G and Marsman, Vera A. M and Kuijf, Mark L and Van Oostenbrugge, Robert J and van Os, Jim and Leentjens, Albert F. G
PLoS One, ISSN 1932-6203, 03/2016, Volume 11, Issue 3, p. e0151195
Background In Parkinson's disease (PD), the complex relationship between motor symptoms, affective states, and contextual factors remains to be elucidated. The... 
MOMENTARY ASSESSMENT | DEPRESSION | MOOD | QUALITY | ANXIETY | FLUCTUATIONS | MULTIDISCIPLINARY SCIENCES | VALIDATION | DAILY-LIFE | ONSET | Activities of Daily Living | Humans | Middle Aged | Female | Male | Aged | Parkinson Disease - physiopathology | Emotions | Parkinson's disease | Diagnosis | Research | Motor ability | Analysis | Risk factors
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9. Full Text Time to treatment with endovascular thrombectomy and outcomes from ischemic stroke: Ameta-analysis
by Saver, Jeffrey L and Goyal, Mayank and Van Der Lugt, Aad and Menon, Bijoy K and Majoie, Charles B.L.M and Dippel, Diederik W and Campbell, Bruce C and Nogueira, Raul G and Demchuk, Andrew M and Tomasello, Alejandro and Cardona, Pere and Devlin, Thomas G and Frei, Donald F and Du Mesnil De Rochemont, Richard and Berkhemer, Olvert A and Jovin, Tudor G and Siddiqui, Adnan H and Van Zwam, Wim H and Davis, Stephen M and Castaño, Carlos and Sapkota, Biggya L and Fransen, Puck S and Molina, Carlos and Van Oostenbrugge, Robert J and Chamorro, Ángel and Lingsma, Hester and Silver, Frank L and Donnan, Geoffrey A and Shuaib, Ashfaq and Brown, Scott and Stouch, Bruce and Mitchell, Peter J and Davalos, Antoni and Roos, Yvo B.W.E.M and Hill, Michael D
JAMA - Journal of the American Medical Association, ISSN 0098-7484, 09/2016, Volume 316, Issue 12, pp. 1279 - 1288
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10. Full Text Response to letter regarding article "Endothelial activation in lacunar stroke subtypes"
by Knottnerus, Iris L.H and Staals, Julie and Van Oostenbrugge, Robert J
Stroke, ISSN 0039-2499, 03/2011, Volume 42, Issue 3, pp. e35 - E35
WHITE-MATTER HYPERINTENSITY | PERIPHERAL VASCULAR DISEASE | CLINICAL NEUROLOGY
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11. Full Text Coronary heart disease and risk for cognitive impairment or dementia: Systematic review and meta-analysis
by Deckers, Kay and Schievink, Syenna H. J and Roiquez, Maria M. F and van Oostenbrugge, Robert J and van Boxtel, Martin P. J and Verhey, Frans R. J and Kohler, Sebastian
PLoS One, ISSN 1932-6203, 09/2017, Volume 12, Issue 9, p. e0184244
Aims/Hypothesis Accumulating evidence suggests an association between coronary heart disease and risk for cognitive impairment or dementia, but no study has... 
INCIDENT DEMENTIA | MYOCARDIAL-INFARCTION | VASCULAR DEMENTIA | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | MIDLIFE | CARDIOVASCULAR-DISEASE | PREVENTION | ATRIAL-FIBRILLATION | LIFE | DECLINE | Myocardial Infarction - epidemiology | Prospective Studies | Cross-Sectional Studies | Humans | Coronary Disease - epidemiology | Risk | Dementia - epidemiology | Cognitive Dysfunction - etiology | Case-Control Studies | Dementia - etiology | Myocardial Infarction - complications | Angina Pectoris - complications | Cognitive Dysfunction - epidemiology | Coronary Disease - complications | Angina Pectoris - epidemiology | Cohort Studies | Myocardial infarction | Brain | Cardiac arrhythmia | Neurosciences | Heart attacks | Cognitive ability | Mental health | Impairment | Cardiovascular disease | Population studies | Cognition | Angina | Medical diagnosis | Lists | Dementia disorders | Heart diseases | Cross sections | Data acquisition | Health risks | Angina pectoris | Estimates | Coronary artery disease | Meta-analysis | Studies | Reviews | Cognition & reasoning | Documents | Data collection | Infarction | Quality assessment | Cardiovascular diseases | Health risk assessment | Psychiatry | Dementia
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12. Full Text Response to Letter Regarding Article “Endothelial Activation in Lacunar Stroke Subtypes”
by Knottnerus, Iris L.H and Staals, Julie and van Oostenbrugge, Robert J
Stroke, ISSN 0039-2499, 03/2011, Volume 42, Issue 3
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13. Full Text Association between Perivascular Spaces and Progression of White Matter Hyperintensities in Lacunar Stroke Patients
by Loos, Caroline M. J and Klarenbeek, Pim and van Oostenbrugge, Robert J and Staals, Julie
PLoS One, ISSN 1932-6203, 09/2015, Volume 10, Issue 9, p. e0137323
Objectives Perivascular spaces are associated with MRI markers of cerebral small vessel disease, including white matter hyperintensities. Although perivascular... 
POPULATION | CADASIL | SILENT BRAIN INFARCTS | MRI | SMALL-VESSEL DISEASE | MULTIDISCIPLINARY SCIENCES | BARRIER | VIRCHOW-ROBIN SPACES | AMBULATORY BLOOD-PRESSURE | LESIONS | SEVERITY | Follow-Up Studies | Humans | Middle Aged | Risk Factors | Male | Basal Ganglia - pathology | Cerebral Small Vessel Diseases - pathology | Disease Progression | Hypertension - pathology | White Matter - pathology | Magnetic Resonance Imaging | Female | Aged | Blood Pressure Monitoring, Ambulatory | Blood-Brain Barrier | Stroke, Lacunar - pathology | Stroke (Disease) | Physiological aspects | Brain | Development and progression | Diagnosis | Research | Hypertension | Basal ganglia | Stroke | Nuclear magnetic resonance--NMR | Markers | Regression analysis | Risk analysis | Substantia alba | Patients | Blood | Risk factors | Ganglia | Neurology | Brain research | Vascular diseases | Magnetic resonance imaging | Blood-brain barrier | Blood pressure | NMR | Nuclear magnetic resonance
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14. Full Text Long-Term Morphological Changes of Symptomatic Lacunar Infarcts and Surroun