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by Gröbner, Susanne N and Worst, Barbara C and Weischenfeldt, Joachim and Buchhalter, Ivo and Kleinheinz, Kortine and Rudneva, Vasilisa A and Johann, Pascal D and Balasubramanian, Gnana Prakash and Segura-Wang, Maia and Brabetz, Sebastian and Bender, Sebastian and Hutter, Barbara and Sturm, Dominik and Pfaff, Elke and Hübschmann, Daniel and Zipprich, Gideon and Heinold, Michael and Eils, Jürgen and Lawerenz, Christian and Erkek, Serap and Lambo, Sander and Waszak, Sebastian and Blattmann, Claudia and Borkhardt, Arndt and Kuhlen, Michaela and Eggert, Angelika and Fulda, Simone and Gessler, Manfred and Wegert, Jenny and Kappler, Roland and Baumhoer, Daniel and Burdach, Stefan and Kirschner-Schwabe, Renate and Kontny, Udo and Kulozik, Andreas E and Lohmann, Dietmar and Hettmer, Simone and Eckert, Cornelia and Bielack, Stefan and Nathrath, Michaela and Niemeyer, Charlotte and Richter, Günther H and Schulte, Johannes and Siebert, Reiner and Westermann, Frank and Molenaar, Jan J and Vassal, Gilles and Witt, Hendrik and Zapatka, Marc and Burkhardt, Birgit and Kratz, Christian P and Witt, Olaf and Tilburg, Cornelis M. Van and Kramm, Christof M and Fleischhack, Gudrun and Dirksen, Uta and Rutkowski, Stefan and Frühwald, Michael and Hoff, Katja Von and Wolf, Stephan and Klingebiel, Thomas and Koscielniak, Ewa and Landgraf, Pablo and Koster, Jan and Resnick, Adam C and Zhang, Jinghui and Liu, Yanling and Zhou, Xin and Waanders, Angela J and Zwijnenburg, Danny A and Raman, Pichai and Brors, Benedikt and Weber, Ursula D and Northcott, Paul A and Pajtler, Kristian W and Kool, Marcel and Piro, Rosario M and Korbel, Jan O and Schlesner, Matthias and Eils, Roland and Jones, David T. W and Lichter, Peter and Chavez, Lukas and Pfister, Stefan M and ICGC PedBrain-Seq Project ICGC and ICGC MMML-Seq Project and ICGC PedBrain-Seq Project
Nature, ISSN 0028-0836, 03/2018, Volume 555, Issue 7696, pp. 321 - 327
Journal Article
Neuro-Oncology, ISSN 1522-8517, 06/2018, Volume 20, Issue suppl_2, pp. i130 - i130
Abstract High-risk medulloblastoma (MB) is a deadly disease with poor overall survival. Survivors suffer from severe treatment-associated morbidity. Patients... 
Abstracts
Journal Article
Pediatric Blood & Cancer, ISSN 1545-5009, 03/2018, Volume 65, Issue 3, pp. e26893 - n/a
Infants with low‐grade glioma (LGG) and diencephalic syndrome have a poor outcome. The patient described here had a desmoplastic infantile astrocytoma... 
BRAF V600E inhibitor | vemurafenib | infant | desmoplastic infantile astrocytoma | low‐grade glioma | child | low-grade glioma | GLIOMA | TUMORS | INHIBITION | ONCOLOGY | PILOCYTIC ASTROCYTOMA | PEDIATRICS | STEM GANGLIOGLIOMA | HEMATOLOGY | EXPRESSION | Gene mutations | Gliomas | Chemotherapy | Inhibitors | Glioma | Addiction | Infants | Children | Astrocytoma
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2016, Volume 65, pp. 91 - 101
Journal Article
Neuro-Oncology, ISSN 1522-8517, 06/2018, Volume 20, Issue suppl_2, pp. i106 - i106
Abstract The main challenge in the clinical management of pilocytic astrocytoma (PA) is its unpredictable growth behavior. PA cells are driven into... 
Abstracts
Journal Article
Neuro-Oncology, ISSN 1522-8517, 06/2017, Volume 19, Issue suppl_4, pp. iv53 - iv53
Individualized treatment approaches require precise and robust diagnostics concerning diagnosis and detection of actionable alterations. The “pediatric... 
Abstracts
Journal Article
Nature medicine, ISSN 1078-8956, 2016, Volume 22, Issue 11, pp. 1314 - 1320
Journal Article
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2017, Volume 19, Issue suppl_6, pp. vi200 - vi200
Pilocytic astrocytoma (PA) is the most frequent pediatric brain tumor. This single-pathway disease exhibits aberrant activation of the MAPK pathway driving the... 
Abstracts
Journal Article
Neuro-Oncology, ISSN 1522-8517, 06/2017, Volume 19, Issue suppl_4, pp. iv33 - iv33
The benign but unpredictable growth behaviour of pilocytic astrocytoma (PA) is thought to originate from variations in proliferation caused by oncogene-induced... 
Abstracts
Journal Article
Neuro-Oncology, ISSN 1522-8517, 06/2017, Volume 19, Issue suppl_4, pp. iv41 - iv42
High-risk medulloblastoma (MB) remains a deadly disease with poor overall survival despite aggressive multi-modal treatment. Survivors suffer from important... 
Abstracts
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2019, Volume 21, Issue Supplement_6, pp. vi231 - vi231
Abstract BACKGROUND TRK fusions are oncogenic drivers of a variety of tumors, many of which can involve the central nervous system (CNS). Larotrectinib is a... 
Journal Article
European Journal of Cancer, ISSN 0959-8049, 06/2019, Volume 114, pp. 27 - 35
Journal Article