Clinical Infectious Diseases, ISSN 1058-4838, 05/2018, Volume 66, Issue 9, pp. 1352 - 1359
markdownabstractBackground The Netherlands has provided unrestricted access to direct-acting antivirals (DAAs) since November 2015. We analyzed the nationwide...
Treatment uptake | HIV/HCV coinfection | Direct-acting antivirals | treatment uptake | INFECTIOUS DISEASES | EFFICACY | SAFETY | SEX | MICROBIOLOGY | IMMUNOLOGY | direct-acting antivirals | INDIVIDUALS | HIV | REINFECTION | MEN | INFECTION | COHORT | AMSTERDAM
Treatment uptake | HIV/HCV coinfection | Direct-acting antivirals | treatment uptake | INFECTIOUS DISEASES | EFFICACY | SAFETY | SEX | MICROBIOLOGY | IMMUNOLOGY | direct-acting antivirals | INDIVIDUALS | HIV | REINFECTION | MEN | INFECTION | COHORT | AMSTERDAM
Journal Article
PLoS ONE, ISSN 1932-6203, 2009, Volume 4, Issue 5, pp. e5647 - e5647
Background: Lipoatrophy is known to be associated with stavudine as part of the treatment for HIV infection, but it is less clear if this serious side effect...
MULTIDISCIPLINARY SCIENCES | Anti-HIV Agents - pharmacology | Humans | Middle Aged | Male | Lamivudine - adverse effects | Lipodystrophy - virology | Body Composition - drug effects | Lipids - blood | Lamivudine - therapeutic use | Adult | Anti-HIV Agents - therapeutic use | Anti-HIV Agents - blood | Biomarkers - metabolism | HIV Infections - blood | Zidovudine - adverse effects | HIV-1 - drug effects | Anti-HIV Agents - adverse effects | HIV Infections - virology | Lopinavir | Lamivudine - blood | Zidovudine - pharmacology | Lipodystrophy - complications | Pyrimidinones - blood | Adolescent | HIV Infections - complications | Glucose - metabolism | HIV Infections - drug therapy | Lipodystrophy - chemically induced | Zidovudine - therapeutic use | Aged | Lamivudine - pharmacology | Zidovudine - blood | Highly active antiretroviral therapy | CT imaging | Care and treatment | AIDS treatment | Physiological aspects | DNA polymerases | Stavudine | HIV (Viruses) | Health aspects | HIV infection | Zidovudine | Therapy | RNA-directed DNA polymerase | Nevirapine | Body fat | Ritonavir | Cardiovascular disease | Standard error | Infections | Density | Body composition | Randomization | Computed tomography | Acquired immune deficiency syndrome--AIDS | Body composition (biology) | Antiretroviral agents | Nucleoside reverse transcriptase inhibitors | Human immunodeficiency virus--HIV | Antiretroviral drugs | Dual energy X-ray absorptiometry | Lamivudine | Cholesterol | Antiretroviral therapy | Side effects | Protease inhibitors | Lipoatrophy | Lipodystrophy | Index Medicus | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
MULTIDISCIPLINARY SCIENCES | Anti-HIV Agents - pharmacology | Humans | Middle Aged | Male | Lamivudine - adverse effects | Lipodystrophy - virology | Body Composition - drug effects | Lipids - blood | Lamivudine - therapeutic use | Adult | Anti-HIV Agents - therapeutic use | Anti-HIV Agents - blood | Biomarkers - metabolism | HIV Infections - blood | Zidovudine - adverse effects | HIV-1 - drug effects | Anti-HIV Agents - adverse effects | HIV Infections - virology | Lopinavir | Lamivudine - blood | Zidovudine - pharmacology | Lipodystrophy - complications | Pyrimidinones - blood | Adolescent | HIV Infections - complications | Glucose - metabolism | HIV Infections - drug therapy | Lipodystrophy - chemically induced | Zidovudine - therapeutic use | Aged | Lamivudine - pharmacology | Zidovudine - blood | Highly active antiretroviral therapy | CT imaging | Care and treatment | AIDS treatment | Physiological aspects | DNA polymerases | Stavudine | HIV (Viruses) | Health aspects | HIV infection | Zidovudine | Therapy | RNA-directed DNA polymerase | Nevirapine | Body fat | Ritonavir | Cardiovascular disease | Standard error | Infections | Density | Body composition | Randomization | Computed tomography | Acquired immune deficiency syndrome--AIDS | Body composition (biology) | Antiretroviral agents | Nucleoside reverse transcriptase inhibitors | Human immunodeficiency virus--HIV | Antiretroviral drugs | Dual energy X-ray absorptiometry | Lamivudine | Cholesterol | Antiretroviral therapy | Side effects | Protease inhibitors | Lipoatrophy | Lipodystrophy | Index Medicus | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
Journal Article
PLoS medicine, ISSN 1549-1277, 2012, Volume 9, Issue 3, p. e1001196
Background: The objective of this study was to assess the benefit of temporary combination antiretroviral therapy (cART) during primary HIV infection (PHI)....
INDIVIDUALS | PLASMA VIREMIA | MEDICINE, GENERAL & INTERNAL | OBSERVATIONAL COHORT | THERAPY | IMMUNODEFICIENCY-VIRUS TYPE-1 | VIROLOGICAL SET-POINT | CELL DECLINE | DRUG-RESISTANCE | IMMUNE FUNCTION | INTERRUPTION | Anti-Retroviral Agents - therapeutic use | Drug Administration Schedule | HIV Infections - virology | Humans | Middle Aged | Adult | Female | HIV Infections - drug therapy | Male | Viral Load | Physiological aspects | Antiviral agents | Care and treatment | HIV (Viruses) | Comparative analysis | Health aspects | Medical research | Acquired immune deficiency syndrome--AIDS | Drug therapy | Human immunodeficiency virus--HIV | AIDS | Human immunodeficiency virus | HIV | Acquired immune deficiency syndrome
INDIVIDUALS | PLASMA VIREMIA | MEDICINE, GENERAL & INTERNAL | OBSERVATIONAL COHORT | THERAPY | IMMUNODEFICIENCY-VIRUS TYPE-1 | VIROLOGICAL SET-POINT | CELL DECLINE | DRUG-RESISTANCE | IMMUNE FUNCTION | INTERRUPTION | Anti-Retroviral Agents - therapeutic use | Drug Administration Schedule | HIV Infections - virology | Humans | Middle Aged | Adult | Female | HIV Infections - drug therapy | Male | Viral Load | Physiological aspects | Antiviral agents | Care and treatment | HIV (Viruses) | Comparative analysis | Health aspects | Medical research | Acquired immune deficiency syndrome--AIDS | Drug therapy | Human immunodeficiency virus--HIV | AIDS | Human immunodeficiency virus | HIV | Acquired immune deficiency syndrome
Journal Article
AIDS, ISSN 0269-9370, 04/2019, Volume 33, Issue 5, pp. 833 - 844
Journal Article
Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 08/2019, Volume 81, Issue 5, pp. 562 - 571
Journal Article
HIV medicine, ISSN 1464-2662, 2018, Volume 19, Issue 3, pp. 216 - 226
Direct-acting antivirals (DAAs) for treatment of chronic hepatitis C virus (HCV) infection can cause drug-drug interactions (DDIs) with combination...
co‐medication | direct‐acting antivirals | HIV | combination antiretroviral therapy | hepatitis C | drug–drug interactions | co-medication | direct-acting antivirals | INFECTIOUS DISEASES | drug-drug interactions | THERAPY | SOFOSBUVIR | INFECTION | Hepacivirus - drug effects | Antiviral Agents - pharmacology | Prospective Studies | Hepatitis C - drug therapy | Antiviral Agents - therapeutic use | Coinfection - drug therapy | Humans | Middle Aged | Male | Practice Patterns, Physicians | Netherlands | Drug Interactions | Observational Studies as Topic | Female | HIV Infections - drug therapy | Retrospective Studies | Sustained Virologic Response | Hepatitis | Complications and side effects | Highly active antiretroviral therapy | Squamous cell carcinoma | Protease inhibitors | Comorbidity | Proteases | Drug interactions | Digital integrated circuits | Hepatitis C virus | Medical personnel | Drugs | Therapy | Physicians | Chronic infection | Viruses | Patients | Antiretroviral therapy | Antiretroviral agents | Human immunodeficiency virus--HIV | Hepatitis C
co‐medication | direct‐acting antivirals | HIV | combination antiretroviral therapy | hepatitis C | drug–drug interactions | co-medication | direct-acting antivirals | INFECTIOUS DISEASES | drug-drug interactions | THERAPY | SOFOSBUVIR | INFECTION | Hepacivirus - drug effects | Antiviral Agents - pharmacology | Prospective Studies | Hepatitis C - drug therapy | Antiviral Agents - therapeutic use | Coinfection - drug therapy | Humans | Middle Aged | Male | Practice Patterns, Physicians | Netherlands | Drug Interactions | Observational Studies as Topic | Female | HIV Infections - drug therapy | Retrospective Studies | Sustained Virologic Response | Hepatitis | Complications and side effects | Highly active antiretroviral therapy | Squamous cell carcinoma | Protease inhibitors | Comorbidity | Proteases | Drug interactions | Digital integrated circuits | Hepatitis C virus | Medical personnel | Drugs | Therapy | Physicians | Chronic infection | Viruses | Patients | Antiretroviral therapy | Antiretroviral agents | Human immunodeficiency virus--HIV | Hepatitis C
Journal Article
HIV medicine, ISSN 1464-2662, 2016, Volume 17, Issue 8, pp. 571 - 580
Lamivudine (3TC) and emtricitabine (FTC) are considered interchangeable in recommended tenofovir disoproxil-fumarate (TDF)-containing combination...
emtricitabine | HIV‐1 | boosted protease inhibitors | antiretroviral therapy | lamivudine | Emtricitabine | HIV-1 | Lamivudine | Antiretroviral therapy | Boosted protease inhibitors | ANTIRETROVIRAL-NAIVE | INFECTIOUS DISEASES | ABACAVIR-LAMIVUDINE | ONCE-DAILY DOLUTEGRAVIR | SUPPRESSED PATIENTS | REVERSE-TRANSCRIPTASE | INITIAL TREATMENT | RESISTANCE PROFILES | MULTICENTER TRIAL | CONTAINING REGIMENS | HIV-1 INFECTION | Emtricitabine - therapeutic use | Humans | Middle Aged | Male | Viral Load | Young Adult | Netherlands | HIV-1 - isolation & purification | Treatment Failure | Adolescent | Lamivudine - therapeutic use | Adult | Anti-HIV Agents - therapeutic use | Female | HIV Infections - drug therapy | Antiretroviral Therapy, Highly Active - methods | Cohort Studies
emtricitabine | HIV‐1 | boosted protease inhibitors | antiretroviral therapy | lamivudine | Emtricitabine | HIV-1 | Lamivudine | Antiretroviral therapy | Boosted protease inhibitors | ANTIRETROVIRAL-NAIVE | INFECTIOUS DISEASES | ABACAVIR-LAMIVUDINE | ONCE-DAILY DOLUTEGRAVIR | SUPPRESSED PATIENTS | REVERSE-TRANSCRIPTASE | INITIAL TREATMENT | RESISTANCE PROFILES | MULTICENTER TRIAL | CONTAINING REGIMENS | HIV-1 INFECTION | Emtricitabine - therapeutic use | Humans | Middle Aged | Male | Viral Load | Young Adult | Netherlands | HIV-1 - isolation & purification | Treatment Failure | Adolescent | Lamivudine - therapeutic use | Adult | Anti-HIV Agents - therapeutic use | Female | HIV Infections - drug therapy | Antiretroviral Therapy, Highly Active - methods | Cohort Studies
Journal Article
AIDS (London, England), ISSN 0269-9370, 2010, Volume 24, Issue 3, pp. 427 - 435
INTRODUCTION: This study describes the characteristics of the metabolic syndrome in HIV-positive patients in the Data Collection on Adverse Events of Anti-HIV...
Observational study | HIV | Metabolic syndrome | Epidemiology | STATEMENT | INFECTIOUS DISEASES | MANAGEMENT | GUIDELINES | COMPONENTS | ADULTS | IMMUNOLOGY | SOCIETY | observational study | metabolic syndrome | epidemiology | VIROLOGY | CARDIOVASCULAR-DISEASE | LIPID PROFILES | COMBINATION ANTIRETROVIRAL THERAPY | ASSOCIATION | HIV-1 | United States - epidemiology | Prevalence | Prospective Studies | HIV Infections - epidemiology | Humans | Middle Aged | Male | CD4 Lymphocyte Count | Antihypertensive Agents - therapeutic use | Metabolic Syndrome - drug therapy | Metabolic Syndrome - diagnosis | HIV Infections - complications | Adult | Female | Hypolipidemic Agents - therapeutic use | Metabolic Syndrome - epidemiology | Cohort Studies
Observational study | HIV | Metabolic syndrome | Epidemiology | STATEMENT | INFECTIOUS DISEASES | MANAGEMENT | GUIDELINES | COMPONENTS | ADULTS | IMMUNOLOGY | SOCIETY | observational study | metabolic syndrome | epidemiology | VIROLOGY | CARDIOVASCULAR-DISEASE | LIPID PROFILES | COMBINATION ANTIRETROVIRAL THERAPY | ASSOCIATION | HIV-1 | United States - epidemiology | Prevalence | Prospective Studies | HIV Infections - epidemiology | Humans | Middle Aged | Male | CD4 Lymphocyte Count | Antihypertensive Agents - therapeutic use | Metabolic Syndrome - drug therapy | Metabolic Syndrome - diagnosis | HIV Infections - complications | Adult | Female | Hypolipidemic Agents - therapeutic use | Metabolic Syndrome - epidemiology | Cohort Studies
Journal Article
HIV medicine, ISSN 1464-2662, 2012, Volume 13, Issue 10, pp. 630 - 635
The aim of the study was to compare health-related quality of life (HRQL) over 96 weeks in patients receiving no treatment or 24 or 60 weeks of combination...
acute HIV infection | health‐related quality of life | primary HIV infection | combination antiretroviral therapy | Health-related quality of life | Primary HIV infection | Acute HIV infection | Combination antiretroviral therapy | TRIAL | INFECTIOUS DISEASES | THERAPY | health-related quality of life | MEDICAL OUTCOMES | Prospective Studies | Drug Administration Schedule | HIV-1 - drug effects | Humans | Middle Aged | HIV Seropositivity - drug therapy | Linear Models | Male | Disease Progression | Viral Load | Young Adult | Time Factors | Adolescent | Quality of Life | Adult | Anti-HIV Agents - therapeutic use | Female | Surveys and Questionnaires | Health Status | Cohort Studies | Highly active antiretroviral therapy | Antiviral agents | Analysis | Gastrointestinal diseases | Drug therapy | HIV (Viruses) | Health aspects | HIV infection | Index Medicus
acute HIV infection | health‐related quality of life | primary HIV infection | combination antiretroviral therapy | Health-related quality of life | Primary HIV infection | Acute HIV infection | Combination antiretroviral therapy | TRIAL | INFECTIOUS DISEASES | THERAPY | health-related quality of life | MEDICAL OUTCOMES | Prospective Studies | Drug Administration Schedule | HIV-1 - drug effects | Humans | Middle Aged | HIV Seropositivity - drug therapy | Linear Models | Male | Disease Progression | Viral Load | Young Adult | Time Factors | Adolescent | Quality of Life | Adult | Anti-HIV Agents - therapeutic use | Female | Surveys and Questionnaires | Health Status | Cohort Studies | Highly active antiretroviral therapy | Antiviral agents | Analysis | Gastrointestinal diseases | Drug therapy | HIV (Viruses) | Health aspects | HIV infection | Index Medicus
Journal Article
Clinical infectious diseases, ISSN 1058-4838, 2015, Volume 60, Issue 1, pp. 143 - 153
Background. Guidelines for treatment of human immunodeficiency virus type 1 (HIV-1) infection consider lamivudine and emtricitabine to be interchangeable...
HIV-1 | emtricitabine | virological failure | antiretroviral therapy | lamivudine | INFECTIOUS DISEASES | EFFICACY | ZIDOVUDINE/LAMIVUDINE | MICROBIOLOGY | RESISTANCE PROFILES | IMMUNOLOGY | DISOPROXIL FUMARATE | CONTAINING REGIMENS | Anti-Retroviral Agents - therapeutic use | HIV Infections - epidemiology | HIV Infections - virology | Humans | Middle Aged | Netherlands - epidemiology | Male | Viral Load | Incidence | HIV-1 - isolation & purification | Treatment Failure | Adult | Female | HIV Infections - drug therapy | Antiretroviral Therapy, Highly Active - methods | Cohort Studies
HIV-1 | emtricitabine | virological failure | antiretroviral therapy | lamivudine | INFECTIOUS DISEASES | EFFICACY | ZIDOVUDINE/LAMIVUDINE | MICROBIOLOGY | RESISTANCE PROFILES | IMMUNOLOGY | DISOPROXIL FUMARATE | CONTAINING REGIMENS | Anti-Retroviral Agents - therapeutic use | HIV Infections - epidemiology | HIV Infections - virology | Humans | Middle Aged | Netherlands - epidemiology | Male | Viral Load | Incidence | HIV-1 - isolation & purification | Treatment Failure | Adult | Female | HIV Infections - drug therapy | Antiretroviral Therapy, Highly Active - methods | Cohort Studies
Journal Article