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1. Proliferation markers for the differential diagnosis of tumor and inflammation
by van Waarde, Aren and Elsinga, Philip H
Current pharmaceutical design, ISSN 1381-6128, 11/2008, Volume 14, Issue 31, pp. 3326 - 3339
Inflammation - pathology | Diagnosis, Differential | Animals | Cell Proliferation | Radiopharmaceuticals - pharmacokinetics | Biomarkers, Tumor - analysis | Humans | Sensitivity and Specificity | Positron-Emission Tomography | Inflammation - diagnostic imaging | Neoplasms - diagnostic imaging | Neoplasms - pathology
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2. Full Text Pridopidine selectively occupies sigma-1 rather than dopamine D2 receptors at behaviorally active doses
by Sahlholm, Kristoffer and Sijbesma, Jurgen W. A and Maas, Bram and Kwizera, Chantal and Marcellino, Daniel and Kuzhuppilly Ramakrishnan, Nisha and Dierckx, Rudi A. J. O and Elsinga, Philip H and van Waarde, Aren
Psychopharmacology, ISSN 0033-3158, 09/2015, Volume 232, Issue 18, pp. 3443 - 3453
C-11-raclopride | ACR16 | C-11-SA4503 | RATS | MicroPET | Kinetic analysis | ANTAGONISM | STABILIZERS PRIDOPIDINE | POSITRON-EMISSION-TOMOGRAPHY | IN-VIVO | (-)-OSU6162 | Receptor occupancy | BINDING | PET | BRAIN | Neurosciences | Biomedicine | 11 C-SA4503 | Pharmacology/Toxicology | Psychiatry | 11 C-raclopride | Pharmacology & Pharmacy | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Raclopride | Animals | Piperazines | Piperidines - metabolism | Rats | Male | Neostriatum - metabolism | Receptors, Dopamine D2 - metabolism | Receptors, sigma - metabolism | Dopamine Antagonists | Carbon Radioisotopes | Complications and side effects | Care and treatment | Dopamine | Metabolites | Huntington's chorea | Influence | Research | Studies | Proteins | Index Medicus | 11C-SA4503 | 11C-raclopride | Original Investigation | Medicin och hälsovetenskap
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3. PET Tracers for Imaging of ABC Transporters at the Blood-Brain Barrier: Principles and Strategies
by Luurtsema, Gert and Elsinga, Philip and Dierckx, Rudi and Boellaard, Ronald and van Waarde, Aren
Current pharmaceutical design, ISSN 1381-6128, 01/2016, Volume 22, Issue 38, pp. 5779 - 5785
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Radioactive Tracers | Animals | Blood-Brain Barrier - chemistry | Humans | ATP-Binding Cassette Transporters - metabolism | Positron-Emission Tomography | Neurodegenerative Diseases - metabolism | Neurodegenerative Diseases - diagnostic imaging | ATP-Binding Cassette Transporters - analysis | Blood-Brain Barrier - metabolism
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4. PET studies on P-glycoprotein function in the blood-brain barrier: How it affects uptake and binding of drugs within the CNS
by Elsinga, Philip H and Hendrikse, N. Harry and Bart, Joost and Vaalburg, Willem and van Waarde, Aren
Current pharmaceutical design, ISSN 1381-6128, 2004, Volume 10, Issue 13, pp. 1493 - 1503
CNS drugs | Verapamil | ATP-binding cassette superfamily of transporters | Positron emission tomography | Carvedilol | PET | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Central Nervous System - diagnostic imaging | ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism | Pharmaceutical Preparations - metabolism | Animals | Blood-Brain Barrier - diagnostic imaging | Central Nervous System - metabolism | Humans | Pharmaceutical Preparations - chemistry | Tomography, Emission-Computed - methods | Blood-Brain Barrier - metabolism | Protein Binding - physiology
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5. Full Text Potential applications for sigma receptor ligands in cancer diagnosis and therapy
by van Waarde, Aren and Rybczynska, Anna A and Ramakrishnan, Nisha K and Ishiwata, Kiichi and Elsinga, Philip H and Dierckx, Rudi A.J.O
Biochimica et biophysica acta. Biomembranes, ISSN 0005-2736, 10/2015, Volume 1848, Issue 10, pp. 2703 - 2714
Drug targeting | Chemotherapy | Antitumor agents | Sigma-2 receptor | Positron emission tomography | Sigma-1 receptor | SYSTEMIC DELIVERY | POTASSIUM CHANNELS | SIRNA DELIVERY | IN-VITRO | STEALTH LIPOSOMES | BIOLOGICAL EVALUATION | TUMOR-CELL DEATH | MEMBRANE COMPONENT 1 | PROGESTERONE-BINDING SITE(S) | PHARMACOLOGICAL EVALUATION | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Prognosis | Humans | Gene Expression Regulation, Neoplastic | Antineoplastic Agents - therapeutic use | Neoplasms - diagnosis | Positron-Emission Tomography | Receptors, sigma - genetics | Antineoplastic Agents - chemistry | Molecular Targeted Therapy | Animals | Neoplasms - genetics | Biomarkers, Tumor - metabolism | Contrast Media - chemistry | Contrast Media - therapeutic use | Fluorine Radioisotopes - therapeutic use | Ligands | Neoplasms - radiotherapy | Biomarkers, Tumor - genetics | Fluorine Radioisotopes - chemistry | Neoplasms - pathology | Receptors, sigma - metabolism | Proteins | Cytokinins | Care and treatment | Lung cancer | Development and progression | Hallucinogenic drugs | Hormones, Sex | Diagnostic imaging | Diagnosis | Health aspects | Cancer
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6. Full Text Avenues to molecular imaging of dying cells: Focus on cancer
by Rybczynska, Anna and Boersma, Henikus and de Jong, Steven and Gietema, Jourik A and Noordzij, Walter and Dierckx, Rudi and Elsinga, Philip H and van Waarde, Aren
Medicinal research reviews, ISSN 0198-6325, 11/2018, Volume 38, Issue 6, pp. 1713 - 1768
early treatment response | PROTEIN-KINASE-C | TC-99M-LABELED C2A DOMAIN | positron emission tomography (PET) | INDUCED TUMOR APOPTOSIS | PRELIMINARY BIOLOGICAL EVALUATION | apoptosis | POSITRON-EMISSION-TOMOGRAPHY | HIS-ANNEXIN A5 | necrosis | single photon emission computed tomography (SPECT) | ACUTE MYOCARDIAL-INFARCTION | IN-VIVO EVALUATION | BINDS ANIONIC PHOSPHOLIPIDS | F-18-FLUOROBENZYL TRIPHENYL PHOSPHONIUM | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Animals | DNA Repair | Humans | Membrane Potential, Mitochondrial | Molecular Imaging | DNA Damage | Neoplasms - diagnostic imaging | Neoplasms - pathology | Apoptosis | Cancer | Tomography | Medical imaging | Index Medicus | Review
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