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Journal of neurology, neurosurgery, and psychiatry, ISSN 0022-3050, 04/2019, Volume 90, Issue 9, p. jnnp-2019-320553
There are several methods to combine survival time and the ALSFRS-R.3 4 The Combined Assessment of Functional and Survival (CAFS) is a well-known composite... 
Clinical trials | Amyotrophic lateral sclerosis | Ostomy | Simulation | Patients
Journal Article
Clinical Neurophysiology, ISSN 1388-2457, 07/2019, Volume 130, Issue 7, pp. e80 - e80
Excitability-testing enables assessment of treatment medication and provides insights into the underlying pathophysiology in neurodegenerative diseases.... 
Nervous system diseases | Analysis
Journal Article
Journal of neurology, neurosurgery, and psychiatry, ISSN 0022-3050, 03/2019, p. jnnp-2018-320211
Journal Article
Clinical Neurophysiology, ISSN 1388-2457, 07/2019, Volume 130, Issue 7, pp. e30 - e31
We extended our longitudinal axon model, which consisted of 41 nodes of Ranvier, with biophysical characteristics unique for human myelinated motor or sensory... 
Analysis | Neurophysiology
Journal Article
Journal of Neurophysiology, ISSN 0022-3077, 07/2019
Immune-mediated neuropathies affect myelinated axons, resulting in conduction slowing or block which may affect motor and sensory axons differently. The... 
Journal Article
Acta neuropathologica, 08/2016, Volume 132, Issue 2, p. 175
Journal Article
Nature Genetics, ISSN 1061-4036, 10/2009, Volume 41, Issue 10, pp. 1047 - 1048
Journal Article
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, ISSN 2167-8421, 01/2018, Volume 19, Issue 1-2, pp. 21 - 28
Objective: To investigate whether symptom development in motor neuron disease (MND) is a random or organized process. Methods: Six hundred patients with... 
upper motor neuron | lower motor neuron | symptom development | amyotrophic lateral sclerosis | Motor neuron disease | FOCALITY | ALS | ADULT-ONSET | NEURODEGENERATION | MECHANISMS | AMYOTROPHIC-LATERAL-SCLEROSIS | NATURAL-HISTORY | CLINICAL NEUROLOGY | DEGENERATION | SPREADING PATTERNS | PROPAGATION | Index Medicus
Journal Article
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, ISSN 2167-8421, 07/2019, pp. 1 - 8
Objective: Spirometry is commonly used as screening tool for respiratory insufficiency in neuromuscular diseases. Despite the well-known effects of reference... 
Journal Article
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, ISSN 2167-8421, 07/2019, pp. 1 - 5
Here, we provide a case-report of an amyotrophic lateral sclerosis (ALS) patient with cognitive deficits best defined as posterior cortical atrophy (PCA). This... 
Journal Article
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, ISSN 2167-8421, 07/2019, pp. 1 - 6
Objective: This study sought to investigate whether a multistep process was also evident in an Australian amyotrophic lateral sclerosis (ALS) population.... 
Journal Article
Journal of Neurology, Neurosurgery & Psychiatry, ISSN 0022-3050, 11/2012, Volume 88, Issue 7, p. 557
Prospective population based-registers of amyotrophic lateral sclerosis (ALS) have operated in Europe for over two decades, and have provided important... 
Journal Article
Neurology, ISSN 0028-3878, 03/2016, Volume 86, Issue 9, pp. 811 - 811
Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive disease of motor neurons, resulting in worsening weakness of voluntary muscles until death... 
CLINICAL NEUROLOGY | Amyotrophic Lateral Sclerosis - diagnosis | Registries | Remission, Spontaneous | Clinical Trials as Topic - statistics & numerical data | Humans | Amyotrophic Lateral Sclerosis - epidemiology | Index Medicus | Abridged Index Medicus
Journal Article
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, ISSN 2167-8421, 07/2019, Volume 20, Issue 5-6, pp. 432 - 440
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive fatal neurodegenerative disease affecting one in 350 people. The aim of Project MinE is to... 
Databrowser | open-access | amyotrophic lateral sclerosis | whole-genome sequencing
Journal Article
Palliative medicine, ISSN 0269-2163, 2017
Informal caregivers of patients with amyotrophic lateral sclerosis experience increased levels of caregiver burden as the disease progresses. Insight in the... 
Journal Article
by Francioli, Laurent C and Menelaou, Anoniki and Pulit, Sara L and van Dijk, Freerk and Palamara, Pier Francesco and Elbers, Clara C and Neerincx, Pieter B. T and Ye, Kai and Guryev, Victor and Kloosterman, Wigard P and Deelen, Patrick and Abdellaoui, Abdel and van Leeuwen, Elisabeth M and van Oven, Mannis and Vermaat, Martijn and Li, Mingkun and Laros, Jeroen F. J and Karssen, Lennart C and Kanterakis, Alexanos and Amin, Najaf and Hottenga, Jouke Jan and Lameijer, Eric-Wubbo and Kattenberg, Mathijs and Dijkstra, Martijn and Byelas, Heorhiy and van Setten, Jessica and van Schaik, Barbera D. C and Bot, Jan and Nijman, Isaäc J and Renkens, Ivo and Marschall, Tobias and Schönhuth, Alexander and Hehir-Kwa, Jayne Y and Handsaker, Robert E and Polak, Paz and Sohail, Mashaal and Vuzman, Dana and Hormozdiari, Fereydoun and van Enckevort, David and Mei, Hailiang and Koval, Vyacheslav and Moed, Matthijs H and van der Velde, K. Joeri and Rivadeneira, Fernando and Estrada, Karol and Medina-Gomez, Carolina and Isaacs, Aaron and McCarroll, Steven A and Beekman, Marian and de Craen, Anton J. M and Suchiman, H. Eka D and Hofman, Albert and Oostra, Ben and Uitterlinden, Ané G and Willemsen, Gonneke and Platteel, Mathieu and Veldink, Jan H and van den Berg, Leonard H and Pitts, Steven J and Potluri, Shobha and Sundar, Purnima and Cox, David R and Sunyaev, Shamil R and den Dunnen, Johan T and Stoneking, Mark and de Knijff, Peter and Kayser, Manfred and Li, Qibin and Li, Yingrui and Du, Yuanping and Chen, Ruoyan and Cao, Hongzhi and Li, Ning and Cao, Sujie and Wang, Jun and Bovenberg, Jasper A and Pe'er, Itsik and Slagboom, P. Eline and van Duijn, Cornelia M and Boomsma, Dorret I and van Ommen, Gert-Jan B and de Bakker, Paul I. W and Swertz, Morris A and Wijmenga, Cisca and LifeLines Cohort Study and Genome Netherlands Consortium and Genome of the Netherlands Consortium and The Genome of the Netherlands Consortium
Nature genetics, ISSN 1061-4036, 2014, Volume 46, Issue 8, pp. 818 - 825
Journal Article
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