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Neuro-Oncology, ISSN 1522-8517, 11/2014, Volume 16, Issue suppl 5, pp. v213 - v214
Isocitrate dehydrogenase 1 (IDH1) is a gene that is mutated in about 70-90% of grade II/III glioma patients. Unfortunately, there are very few good model... 
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 2008, Volume 31, Issue 1, pp. 127 - 132
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2018, Volume 13, Issue 6, pp. e0199737 - e0199737
Introduction The gene encoding isocitrate dehydrogenase 1 (IDH1) is frequently mutated in several tumor types including gliomas. The most prevalent mutation in... 
MAFFUCCI SYNDROME | OLLIER DISEASE | GLIOMAS | MUTANT IDH1 | MULTIDISCIPLINARY SCIENCES | ISOCITRATE DEHYDROGENASE | D-2-HYDROXYGLUTARATE | SUBVENTRICULAR ZONE | MUTATIONS | DIFFERENTIATION | TUMORS | Drug Screening Assays, Antitumor - methods | Glioma - enzymology | Zebrafish Proteins - metabolism | Humans | Neoplasms, Experimental - enzymology | Isocitrate Dehydrogenase - genetics | Mutation, Missense | Animals, Genetically Modified - metabolism | Zebrafish - genetics | Glioma - genetics | Neoplasms, Experimental - pathology | Animals | Animals, Genetically Modified - genetics | Glioma - pathology | Zebrafish - metabolism | Neoplasms, Experimental - genetics | Isocitrate Dehydrogenase - metabolism | Zebrafish Proteins - genetics | Neoplasms, Experimental - drug therapy | Glioma - drug therapy | Amino Acid Substitution | Physiological aspects | Genetic aspects | Models | Gene mutations | Growth | Zebra fish | Brain | Nestin | Dehydrogenases | p53 Protein | Leukemia | Brain tumors | Kinases | Drug screening | Transgenic fish | Eggs | Histidine | Missense mutation | Arginine | Rodents | Collagen (type IV) | Cytosine | Isocitrate dehydrogenase | Enzymes | Phenotypes | Zebrafish | Functional analysis | Gene expression | Medical screening | Mutants | Neurology | Screening | Decarboxylation | In vivo methods and tests | Mutation | Tumors | Index Medicus
Journal Article
by Springelkamp, Henriët and Iglesias, Aiana I and Mishra, Aniket and Höhn, René and Wojciechowski, Robert and Khawaja, Anthony P and Nag, Abhishek and Wang, Ya Xing and Wang, Jie Jin and Cuellar-Partida, Gabriel and Gibson, Jane and Bailey, Jessica N. Cooke and Vithana, Eranga N and Gharahkhani, Puya and Boutin, Thibaud and Ramdas, Wishal D and Zeller, Tanja and Luben, Robert N and Yonova-Doing, Ekaterina and Viswanathan, Ananth C and Yazar, Seyhan and Cree, Angela J and Haines, Jonathan L and Koh, Jia Yu and Souzeau, Emmanuelle and Wilson, James F and Amin, Najaf and Müller, Christian and Venturini, Cristina and Kearns, Lisa S and Kang, Jae Hee and Tham, Yih Chung and Zhou, Tiger and van Leeuwen, Elisabeth M and Nickels, Stefan and Sanfilippo, Paul and Liao, Jiemin and van der Linde, Herma and Zhao, Wanting and van Koolwijk, Leonieke M. E and Zheng, Li and Rivadeneira, Fernando and Baskaran, Mani and van der Lee, Sven J and Perera, Shamira and de Jong, Paulus T. V. M and Oostra, Ben A and Uitterlinden, Ané G and Fan, Qiao and Hofman, Albert and Tai, E.-Shyong and Vingerling, Johannes R and Sim, Xueling and Wolfs, Roger C. W and teo, Yik Ying and Lemij, Hans G and Khor, Chiea Chuen and Willemsen, Rob and Lackner, Karl J and Aung, Tin and Jansonius, Nomdo M and Montgomery, Grant and Wild, Philipp S and Young, Terri L and Burdon, Kathryn P and Hysi, Pirro G and Pasquale, Louis R and Wong, Tien Yin and Klaver, Caroline C. W and Hewitt, Alex W and Jonas, Jost B and Mitchell, Paul and Lotery, Anew J and Foster, Paul J and Vitart, Veronique and Pfeiffer, Norbert and Craig, Jamie E and Mackey, David A and Hammond, Christopher J and Wiggs, Janey L and Cheng, Ching-Yu and van Duijn, Cornelia M and Macgregor, Stuart and NEIGHBORHOOD Consortium
Human molecular genetics, ISSN 0964-6906, 2017, Volume 26, Issue 2, pp. 438 - 453
Journal Article
Journal Article
DMM Disease Models and Mechanisms, ISSN 1754-8403, 03/2019, Volume 12, Issue 3, p. dmm037762
Microglia are brain-resident macrophages, which have specialized functions important in brain development and in disease. They colonize the brain in early... 
Macrophages | Hematopoiesis | Brain development | Reverse genetic screen | Microglia | CRISPR | DIFFERENTIAL EXPRESSION | ZEBRAFISH | MICROGLIA EMERGE | RECEPTOR | PATHOLOGY | IL-34 | LANGERHANS CELLS | CELL BIOLOGY | ADULT MICROGLIA | MAINTENANCE | HEREDITARY DIFFUSE LEUKOENCEPHALOPATHY
Journal Article
Glia, ISSN 0894-1491, 01/2017, Volume 65, Issue 1, pp. 138 - 149
Microglia are brain resident macrophages important for brain development, connectivity, homeostasis and disease. However, it is still largely unclear how... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2002, Volume 99, Issue 11, pp. 7548 - 7553
Journal Article