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by Gröbner, Susanne N and Worst, Barbara C and Weischenfeldt, Joachim and Buchhalter, Ivo and Kleinheinz, Kortine and Rudneva, Vasilisa A and Johann, Pascal D and Balasubramanian, Gnana Prakash and Segura-Wang, Maia and Brabetz, Sebastian and Bender, Sebastian and Hutter, Barbara and Sturm, Dominik and Pfaff, Elke and Hübschmann, Daniel and Zipprich, Gideon and Heinold, Michael and Eils, Jürgen and Lawerenz, Christian and Erkek, Serap and Lambo, Sander and Waszak, Sebastian and Blattmann, Claudia and Borkhardt, Arndt and Kuhlen, Michaela and Eggert, Angelika and Fulda, Simone and Gessler, Manfred and Wegert, Jenny and Kappler, Roland and Baumhoer, Daniel and Burdach, Stefan and Kirschner-Schwabe, Renate and Kontny, Udo and Kulozik, Andreas E and Lohmann, Dietmar and Hettmer, Simone and Eckert, Cornelia and Bielack, Stefan and Nathrath, Michaela and Niemeyer, Charlotte and Richter, Günther H and Schulte, Johannes and Siebert, Reiner and Westermann, Frank and Molenaar, Jan J and Vassal, Gilles and Witt, Hendrik and Burkhardt, Birgit and Kratz, Christian P and Witt, Olaf and van Tilburg, Cornelis M and Kramm, Christof M and Fleischhack, Gudrun and Dirksen, Uta and Rutkowski, Stefan and Frühwald, Michael and von Hoff, Katja and Wolf, Stephan and Klingebiel, Thomas and Koscielniak, Ewa and Landgraf, Pablo and Koster, Jan and Resnick, Adam C and Zhang, Jinghui and Liu, Yanling and Zhou, Xin and Waanders, Angela J and Zwijnenburg, Danny A and Raman, Pichai and Brors, Benedikt and Weber, Ursula D and Northcott, Paul A and Pajtler, Kristian W and Kool, Marcel and Piro, Rosario M and Korbel, Jan O and Schlesner, Matthias and Eils, Roland and Jones, David T. W and Lichter, Peter and Chavez, Lukas and Zapatka, Marc and Pfister, Stefan M and ICGC PedBrain-Seq Project ICGC and ICGC MMML-Seq Project and ICGC PedBrain-Seq Project
Nature (London), ISSN 1476-4687, 02/2018, Volume 555, Issue 7696, pp. 321 - 327
... A. Rudneva [5, 8]; Pascal D. Johann [1, 2, 3, 4]; Gnana Prakash Balasubramanian [1, 2, 9]; Maia Segura-Wang [5]; Sebastian Brabetz [1, 2, 3]; Sebastian Bender [1, 2... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Gene mutations | Genomics | Oncology, Experimental | Genetic aspects | Research | Health aspects | Cancer in children | Cancer | Medical research | Young adults | p53 Protein | Genes | Clinical trials | Workflow | Genomes | Neoplasms | Studies | Alterations | Genetic analysis | Adults | Mutation | Children | Adolescents | Signatures | Bioinformatics | Tumors | Index Medicus
Journal Article
Cancer cell, ISSN 1535-6108, 03/2012, Volume 21, Issue 3, pp. 418 - 429
Pancreatic ductal adenocarcinomas (PDAs) are characterized by a robust fibroinflammatory response. We show here that this desmoplastic reaction generates... 
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Adenocarcinoma - pathology | Cell Adhesion Molecules - administration & dosage | Stromal Cells - pathology | Pancreatic Neoplasms - blood supply | Deoxycytidine - pharmacology | Hyaluronic Acid - physiology | Polyethylene Glycols - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Pancreatic Neoplasms - drug therapy | Deoxycytidine - therapeutic use | Stromal Cells - drug effects | Hyaluronoglucosaminidase - administration & dosage | Drug Evaluation, Preclinical | Hyaluronoglucosaminidase - therapeutic use | Tumor Microenvironment - drug effects | Animals, Genetically Modified | Deoxycytidine - administration & dosage | Pancreatic Neoplasms - pathology | Microvessels - drug effects | Adenocarcinoma - drug therapy | Carcinoma, Pancreatic Ductal - pathology | Extracellular Fluid - drug effects | Polyethylene Glycols - administration & dosage | Adenocarcinoma - blood supply | Hyaluronoglucosaminidase - pharmacology | Carcinoma, Pancreatic Ductal - drug therapy | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Hyaluronic Acid - metabolism | Mice | Carcinoma, Pancreatic Ductal - blood supply | Cell Adhesion Molecules - therapeutic use | Deoxycytidine - analogs & derivatives | Enzymes | Medical colleges | Care and treatment | Glycosaminoglycans | Oncology, Experimental | Research | Chemotherapy | Universities and colleges | Drug therapy | Hyaluronic acid | Public health | Tumors | Cancer | Index Medicus
Journal Article
PLoS genetics, ISSN 1553-7404, 02/2014, Volume 10, Issue 2, pp. e1004135 - e1004135
Journal Article
The New England journal of medicine, ISSN 1533-4406, 10/2013, Volume 369, Issue 18, pp. 1691 - 1703
Journal Article
2019, Cancer treatment and research, ISBN 3030163903, Volume 178, 285
This book presents the latest advances in precision medicine in some of the most common cancer types, including hematological, lung and breast malignancies. It... 
Cancer-Treatment | Personalized medicine | Oncology
eBook
Journal Article
by Wang-Gillam, Andrea and Li, Chung-Pin and Bodoky, György and Dean, Andrew and Shan, Yan-Shen and Jameson, Gayle and Macarulla, Teresa and Lee, Kyung-Hun and Cunningham, David and Blanc, Jean F and Hubner, Richard A and Chiu, Chang-Fang and Schwartsmann, Gilberto and Siveke, Jens T and Braiteh, Fadi and Moyo, Victor and Belanger, Bruce and Dhindsa, Navreet and Bayever, Eliel and Von Hoff, Daniel D and Chen, Li-Tzong and Adoo, Clarence and Anderson, Thomas and Asselah, Jamil and Azambuja, Alan and Bampton, Carolyn and Barrios, Carlos Henrique and Bekaii-Saab, Tanios and Bohuslav, Melichar and Chang, David and Chen, Jen-Shi and Chen, Yeu-Chin and Choi, Hye Jin and Chung, Ik Joo and Chung, Vincent and Csoszi, Tibor and Cubillo, Antonio and DeMarco, Linda and de Wit, Maike and Dragovich, Tomislav and Edenfield, William and Fein, Luis Enrique and Franke, Fábio and Fuchs, Martin and Gonzales-Cruz, Vega and Gozza, Alberto and Fernando, Rivera Herrero and Iaffaioli, Rosario and Jakesova, Jitka and Kahan, Zsuzsanna and Karimi, Misagh and Kim, Jun Suk and Korbenfeld, Ernesto and Lang, Istvan and Lee, Fa-Chyi and Lee, Kuan-Der and Lipton, Lara and Ma, Wen Wee and Mangel, Laszlo and Mena, Raul and Palmer, Daniel and Pant, Shubham and Park, Joon Oh and Piacentini, Paolo and Pelzer, Uwe and Plazas, Javier Gallego and Prasad, Cooray and Rau, Kun-Ming and Raoul, Jean-Luc and Richards, Donald and Ross, Paul and Schlittler, Luis and Smakal, Martin and Stahalova, Vladimira and Sternberg, Cora and Seufferlein, Thomas and Tebbutt, Niall and Vinholes, Jeferson Jose and Wadlow, Raymond and Wenczl, Milkos and Wong, Mark and NAPOLI-1 Study Group and NAPOLI-1 Study Grp
The Lancet (British edition), ISSN 0140-6736, 02/2016, Volume 387, Issue 10018, pp. 545 - 557
Summary Background Nanoliposomal irinotecan showed activity in a phase 2 study in patients with metastatic pancreatic ductal adenocarcinoma previously treated... 
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Leucovorin - administration & dosage | Humans | Middle Aged | Male | Fatigue - chemically induced | Diarrhea - chemically induced | Pancreatic Neoplasms - drug therapy | Neoplasm Metastasis | Fluorouracil - administration & dosage | Leucovorin - adverse effects | Fluorouracil - adverse effects | Camptothecin - administration & dosage | Carcinoma, Pancreatic Ductal - mortality | Deoxycytidine - adverse effects | Female | Pancreatic Neoplasms - mortality | Neutropenia - chemically induced | Camptothecin - analogs & derivatives | Camptothecin - adverse effects | Deoxycytidine - administration & dosage | Kaplan-Meier Estimate | Treatment Outcome | Carcinoma, Pancreatic Ductal - drug therapy | Irinotecan | Vomiting - chemically induced | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Liposomes | Deoxycytidine - analogs & derivatives | Antimitotic agents | Medical colleges | Pancreatic cancer | Leucovorin | Product development | Research institutes | Metastasis | Antineoplastic agents | Analysis | Antigens | Chemotherapy | Medical prognosis | Clinical trials | Drug dosages | Cancer therapies | Tumors | Adenocarcinoma | Therapy | Gemcitabine | Toxicity | Evidence-based medicine | Metastases | Nanoparticles | Randomization | Vomiting | Safety management | Toxic diseases | Neutropenia | Folinic acid | Lymphatic system | Medical treatment | Diarrhea | FDA approval | Survival | Patients | Acids | Equivalence | Interactive systems | Index Medicus | Abridged Index Medicus
Journal Article