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Biochemical and Biophysical Research Communications, ISSN 0006-291X, 11/2019, Volume 519, Issue 4, pp. 697 - 704
At present, whether α -adrenoceptors in the prelimbic cortex (PrL) are involved in Parkinson's disease-related anxiety is unclear. We examined the effects of... 
Prelimbic cortex | Anxiety | Parkinson's disease | α2-adrenoceptors | Rat
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 12/2010, Volume 213, Issue 2, pp. 161 - 174
Agmatine [2-(4-aminobutyl)guanidine] is an endogenous amine proposed as a neurotransmitter/neuromodulator that binds to multiple target receptors in brain.... 
Locomotor sensitization | α2-Adrenoceptors | Agmatine | Nicotine | Adrenoceptors
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 11/2019, Volume 382, p. 114743
Studies have shown that dexmedetomidine (DEX), a potent α -adrenoceptors agonist provides neuroprotection through suppression of inflammatory response. In... 
6-OHDA | TNF-α | α2-Adrenoceptors | KATP Channels | IL-6 | Dexmedetomidine
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 09/2017, Volume 138, pp. 38 - 50
Searching for improved antagonists of α -adrenoceptors, a thorough theoretical study comparing the aromaticity of phenyl-, pyridinyl-, thiophenyl- and... 
Aromaticity | α2-Adrenoceptors | Bioisosterism | Antagonists | Thiophene | Thiazole | Guanidinium | Affinity constants | Adrenoceptors | Index Medicus
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 04/2017, Volume 800, pp. 81 - 95
Analytical pharmacology draws heavily on the concept of equilibrium of agonist and silent antagonist concentrations competing at a specific receptor site. This... 
Prazosin | Mesenteric artery | α2-adrenoceptors | Yohimbine | Desipramine | Clonidine | Right atria | Benextramine | adrenoceptors
Journal Article
Asian Journal of Pharmaceutical and Clinical Research, ISSN 0974-2441, 09/2018, Volume 11, Issue 9, pp. 502 - 508
Objective: The study was carried out to investigate the antidiarrheal activity of ethanolic leaf extract of Eriobotrya japonica (EEJ) using various models of... 
Enteropooling | Cytotoxicity | Eriobotrya japonica | α2-adrenoceptors | Anti-secretory
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 09/2017, Volume 93, pp. 939 - 947
Agmatine and GABA have been abundantly expressed in brain nuclei involved in regulation of energy homeostasis and promoting stimulation of food intake in... 
GABA | Satiated rats | α2-adrenoceptors | Food intake | Agmatine | adrenoceptors
Journal Article
Journal of hypertension, ISSN 0263-6352, 2/2011, Volume 29, Issue 2, pp. 251 - 256
Journal Article
Medicinal Research Reviews, ISSN 0198-6325, 03/2009, Volume 29, Issue 2, pp. 339 - 368
It is well known that norepinephrine is involved in the control of pain by modulating pain‐related responses through various pathways. α2‐Adrenergic agonists... 
α2‐agonists | α2‐adrenoceptors | imidazoles derivatives | analgesia | Analgesia | agonists | adrenoceptors | Imidazoles derivatives
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 10/2016, Volume 7, Issue 10, pp. 956 - 961
Tolerance and dependence associated with chronic opioid exposure result from molecular, cellular, and neural network adaptations. Such adaptations concern... 
agmatine biological profile | adrenoceptors | imidazolines | combined interactions | opioid addiction
Journal Article
Biological Psychiatry, ISSN 0006-3223, 2013, Volume 73, Issue 1, pp. 54 - 62
Journal Article
Journal of Cerebral Blood Flow & Metabolism, ISSN 0271-678X, 10/2011, Volume 31, Issue 10, pp. e1 - e7
We assessed the neuroprotective potential of α2-adrenoceptors in ischemic stroke using mice with targeted deletions of individual α2-adrenoceptor subtypes... 
clonidine | blood pressure | experimental stroke | α2-adrenoceptors | neuroprotection | hemodynamics | Negative Result
Journal Article
Journal of Pain, ISSN 1526-5900, 2016, Volume 17, Issue 11, pp. 1164 - 1173
Abstract In healthy humans, high-frequency electrical stimulation (HFS) of the forearm not only evokes local signs of central sensitization but also triggers... 
Anesthesia & Perioperative Care | Pain Medicine | opioid receptors | central sensitization | High-frequency electrical stimulation | α2-adrenoceptors | conditioned pain modulation | adrenoceptors
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 11/2009, Volume 158, Issue 5, pp. 1344 - 1355
Background and purpose:  In mouse tail arteries, selective α2-adrenoceptor antagonism with rauwolscine caused powerful dilation during constriction to the... 
endothelium | α2-adrenoceptors | phenylephrine | cirazoline | α1-adrenoceptors
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 01/2015, Volume 172, Issue 2, pp. 388 - 402
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 09/2005, Volume 25, Issue 39, pp. 8988 - 8994
Neuropathic pain may be primarily driven by immune responses in peripheral nerves. Peripherally released catecholamines may exacerbate neuropathic pain and... 
Neuritis | Clonidine | Inflammation | α2-adrenoceptors | Cytokines | Neuropathic pain | Behavioral | neuropathic pain | inflammation | clonidine | Cognitive | cytokines | neuritis | Systems
Journal Article