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α-klotho (64) 64
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alpha-klotho (46) 46
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vitamin-d metabolism (9) 9
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glucuronidase - genetics (8) 8
klotho (8) 8
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hyperphosphatemia (6) 6
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mice, inbred c57bl (6) 6
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aged, 80 and over (5) 5
alpha klotho (5) 5
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dominant hypophosphatemic rickets (5) 5
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fibroblast growth factors - genetics (5) 5
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hormone klotho (5) 5
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Aging, ISSN 1945-4589, 06/2018, Volume 10, Issue 6, pp. 1442 - 1453
Progressive loss of tissue homeostasis is a hallmark of numerous age-related pathologies, including osteoarthritis (OA). Accumulation of senescent chondrocytes... 
Journal Article
Kidney International, ISSN 0085-2538, 12/2015, Volume 88, Issue 6, pp. 1442 - 1444
α-Klotho is an interesting new biomarker in kidney and cardiovascular disease. As α-Klotho is primarily expressed in renal epithelial tissue, various papers... 
α-Klotho | protease inhibitor | catheter urine | stability | Catheter urine | Stability | Protease inhibitor | UROLOGY & NEPHROLOGY | alpha-Klotho
Journal Article
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 09/2019, Volume 141, pp. 383 - 392
A thorough understanding of epigenetics regulatory mechanisms of premature ovarian failure (POF) is still lacking. Here, we found that cyclophosphamide induced... 
Oxidative stress | α-Klotho | microRNA | Ovarian granulosa cells | Autophagy | Premature ovarian failure | BIOCHEMISTRY & MOLECULAR BIOLOGY | INSUFFICIENCY | PROLIFERATION | INDUCTION | TRANSPLANTATION | PLURIPOTENT STEM-CELLS | LONGEVITY | GENE | MOUSE MODEL | ENDOCRINOLOGY & METABOLISM | alpha-Klotho | PROMOTES
Journal Article
Cell Reports, ISSN 2211-1247, 09/2019, Volume 28, Issue 11, pp. 2767 - 2776.e5
The hormone αKlotho regulates lifespan in mice, as knockouts die early of what appears to be accelerated aging due to hyperphosphatemia and soft tissue... 
cardiovascular system | aging | calcification | zebrafish | αKlotho | Klotho | FGF23 | PHOSPHATE | OSTEOCLAST | PLASMA KLOTHO | ARTERIAL CALCIFICATION | MINERALIZATION | FISH | ATHEROSCLEROSIS | BONE | CHRONIC KIDNEY-DISEASE | CELL BIOLOGY
Journal Article
Journal of Atherosclerosis and Thrombosis, ISSN 1340-3478, 2015
Aim: Fibroblast growth factor 23 (FGF23) and α-Klotho have been recently identified to play a crucial role in calcium/phosphate metabolism. We herein... 
Coronary artery | Calcification | α-Klotho | Aortic valve | FGF23
Journal Article
Trends in Glycoscience and Glycotechnology, ISSN 0915-7352, 2018, Volume 30, Issue 176, pp. E175 - J152
Journal Article
Journal of Clinical Biochemistry and Nutrition, ISSN 0912-0009, 2018
In this study, we investigated the relationship between age-related changes in renal α-Klotho gene expression, vitamin D metabolism and the responsiveness of... 
vitamin D metabolism | age-related change | α-Klotho | inorganic phosphate | mice
Journal Article
American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 08/2018, Volume 315, Issue 2, pp. F353 - F363
Loss of ubiquitin COOH-terminal hydrolase L1 (UCHL1), a deubiquitinating enzyme required for neuronal function, led to hyperphosphatemia accompanied by... 
Hyperphosphatemia | UCHL1 | α-klotho | UCH-L1 | Phosphate | PHYSIOLOGY | VITAMIN-D METABOLISM | FIBROBLAST-GROWTH-FACTOR-23 | RENAL DAMAGE | phosphate | INORGANIC-PHOSPHATE | GENE | hyperphosphatemia | UROLOGY & NEPHROLOGY | MINERAL METABOLISM | MICE | alpha-klotho | CHRONIC KIDNEY-DISEASE | 1,25-DIHYDROXYVITAMIN-D | FGF23
Journal Article
Journal Article
American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 04/2013, Volume 304, Issue 8, pp. E863 - E873
Touchberry CD, Green TM, Tchikrizov V, Mannix JE, Mao TF, Carney BW, Girgis M, Vincent RJ, Wetmore LA, Dawn B, Bonewald LF, Stubbs JR, Wacker MJ. FGF23 is a... 
α-klotho | Chronic kidney disease | Pathological cardiac hypertrophy | Col4a3 | Fibroblast growth factor 23 | Cardiac function | chronic kidney disease | PHYSIOLOGY | fibroblast growth factor 23 | RECEPTOR | NATRIURETIC PEPTIDE | LEFT-VENTRICULAR HYPERTROPHY | HL-1 CARDIOMYOCYTES | ENDOCRINOLOGY & METABOLISM | GROWTH-FACTOR 23 | HEMODIALYSIS-PATIENTS | MINERAL METABOLISM | cardiac function | pathological cardiac hypertrophy | alpha-klotho | CHRONIC KIDNEY-DISEASE | EXPRESSION | SYSTOLIC HEART-FAILURE | Calcium - metabolism | Myocardial Contraction - physiology | Fibroblast Growth Factors - genetics | Male | Autoantigens - genetics | Fibroblast Growth Factors - metabolism | Receptors, Fibroblast Growth Factor - genetics | Female | Nephritis, Hereditary - physiopathology | Disease Models, Animal | Myocytes, Cardiac - cytology | Cardiomegaly - physiopathology | Nephritis, Hereditary - genetics | Fibroblast Growth Factors - pharmacology | Mice, Inbred Strains | Mice, Knockout | Animals | Myocytes, Cardiac - drug effects | Nephritis, Hereditary - metabolism | Glucuronidase - genetics | Myocytes, Cardiac - physiology | Collagen Type IV - genetics | Mice | Primary Cell Culture | Cardiomegaly - genetics | Cardiomegaly - metabolism | Calcium, Dietary | Heart enlargement | Biological transport, Active | Physiological aspects | Fibroblast growth factors | Research | Muscle contraction | Health aspects
Journal Article
Current Opinion in Nephrology and Hypertension, ISSN 1062-4821, 2014, Volume 23, Issue 4, pp. 331 - 339
Journal Article
Clinica Chimica Acta, ISSN 0009-8981, 01/2018, Volume 476, pp. 44 - 48
Men and women react differently to some disease states, and women are reported to be more sensitive than men to the toxic effects of smoking. We examined the... 
Fibroblast growth factor-21 | α-Klotho | Sex differences | Inflammation | Metabolic disorders | Smoking | DIAGNOSIS | RISK-FACTORS | ATHEROSCLEROSIS | TOBACCO | LUNG-CANCER | REGULATOR | DISEASE | alpha-Klotho | MEDICAL LABORATORY TECHNOLOGY | LIFE | Women | Fibroblast growth factors | Interleukins | Health aspects | Index Medicus
Journal Article