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Neuroscience Letters, ISSN 0304-3940, 02/2018, Volume 665, pp. 80 - 85
Amyloid precursor protein (APP) proteolysis is essential for the production of β-amyloid peptides (Aβ) that form senile plaques in Alzheimer’s disease (AD)... 
Chitosan oligosaccharides | β-Site amyloid precursor protein cleaving enzyme 1 (BACE1) | Alzheimer's disease | β-Amyloid peptide | ACID | REDUCTION | beta-Amyloid peptide | enzyme 1 (BACE1) | beta-Site amyloid precursor protein cleaving | PATHOLOGY | TRANSGENIC MOUSE MODEL | PLAQUE | NEUROSCIENCES | IMPAIRMENT
Journal Article
Biochemical Journal, ISSN 0264-6021, 01/2012, Volume 441, Issue 1, pp. 285 - 295
Insulin resistance and impaired glucose homoeostasis are important indicators of Type 2 diabetes and are early risk factors of AD (Alzheimer's disease). An... 
β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) | Glucose uptake | Uncoupling protein (UCP) | Insulin sensitivity | Liver | Skeletal muscle | BETA-SECRETASE ACTIVITY | HIGH-FAT-DIET | beta-site amyloid precursor protein-cleaving enzyme 1 (BACE1) | liver | ALZHEIMERS-DISEASE | FOOD-INTAKE | BIOCHEMISTRY & MOLECULAR BIOLOGY | AMYLOID PRECURSOR PROTEIN | BROWN ADIPOSE-TISSUE | KNOCKOUT MICE | insulin sensitivity | glucose uptake | RESISTANCE | UNCOUPLING PROTEIN-3 | skeletal muscle | uncoupling protein (UCP) | GROWTH-FACTOR EXPRESSION | Amyloid Precursor Protein Secretases - genetics | Cell Line | Dietary Fats - adverse effects | Obesity - chemically induced | Ion Channels | Insulin Resistance | Gene Expression Regulation - physiology | Blood Glucose | Glucose - genetics | Aspartic Acid Endopeptidases - genetics | Mitochondrial Proteins | Obesity - genetics | Mice, Knockout | Obesity - metabolism | Amyloid Precursor Protein Secretases - metabolism | Myoblasts - metabolism | Animals | Adiposity | Diet | Aspartic Acid Endopeptidases - metabolism | Dietary Fats - administration & dosage | Glucose - metabolism | Mice | Uncoupling Protein 1 | Index Medicus | WT, wild-type | AMPK, AMP-activated protein kinase | FFA, free fatty acid | HBS, Hepes-buffered saline | PKB, protein kinase B | Aβ, β-amyloid peptide | DMEM, Dulbecco's modified Eagle's medium | HFD, high-fat diet | ITT, insulin tolerance test | OGTT, oral glucose tolerance test | qRT-PCR, quantitative real-time PCR | IGTT, intraperitoneal glucose tolerance test | RMR, resting metabolic rate | BAT, brown adipose tissue | FBS, fetal bovine serum | RQ, respiratory quotient | T4, thyroxine | WAT, white adipose tissue | AD, Alzheimer's disease | TG, triacylglycerol | qMR, quantitative magnetic resonance | PDK, phosphoinositide-dependent kinase | UCP, uncoupling protein | ADDL, Aβ-derived diffusible ligands | BACE1, β-site amyloid precursor protein-cleaving enzyme 1 | APP, amyloid precursor protein | IRS, insulin receptor substrate
Journal Article
FEBS Journal, ISSN 1742-464X, 03/2010, Volume 277, Issue 6, pp. 1503 - 1518
Journal Article
Chemical and Pharmaceutical Bulletin, ISSN 0009-2363, 2015, Volume 63, Issue 11, pp. 955 - 960
Two new compounds (2, 3) and 20 known compounds (1, 4-22) were isolated from the heartwood of Juniperus chinensis LINNE (Cupressaceae), and their structures... 
Journal Article
Chemical and Pharmaceutical Bulletin, ISSN 0009-2363, 2015, Volume 63, Issue 11, pp. 955 - 960
Two new compounds (2, 3) and 20 known compounds (1, 4–22) were isolated from the heartwood of Juniperus chinensis LINNE (Cupressaceae), and their structures... 
9′-methoxycalocedrin | β-site amyloid precursor protein cleaving enzyme 1 (BACE1) | Cupressaceae | 5,7,4′-trihydroxy-2-styrylchromone | Juniperus chinensis | α-methyl artoflavanocoumarin | GLYCOSIDES | 9 '-methoxycalocedrin | CHEMISTRY, MEDICINAL | ALZHEIMERS-DISEASE | LEAVES | LAMB | FLAVONOIDS | DILIGNOL | CHEMISTRY, MULTIDISCIPLINARY | 5,7,4 '-trihydroxy-2-styrylchromone | SESQUITERPENES | CHEMICAL-CONSTITUENTS | alpha-methyl artoflavanocoumarin | CONIFER NEEDLES | PHARMACOLOGY & PHARMACY | beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) | EXTRACT | Plant Extracts - chemistry | Aspartic Acid Endopeptidases - antagonists & inhibitors | Lignans - chemistry | Plant Extracts - pharmacology | Humans | Juniperus - chemistry | Cholinesterase Inhibitors - chemistry | Electrophorus | Plant Extracts - isolation & purification | Lignans - pharmacology | Lignans - isolation & purification | Chromones - chemistry | Amyloid Precursor Protein Secretases - metabolism | Animals | Cholinesterase Inhibitors - pharmacology | Aspartic Acid Endopeptidases - metabolism | Horses | Chromones - isolation & purification | Cholinesterase Inhibitors - isolation & purification | Flavonoids - isolation & purification | Flavonoids - pharmacology | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Chromones - pharmacology | Flavonoids - chemistry
Journal Article
Biochemical Society Transactions, ISSN 0300-5127, 06/2007, Volume 35, Issue 3, pp. 571 - 573
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 07/2010, Volume 114, Issue 2, pp. 374 - 385
Journal Article
Journal Article
FEBS Letters, ISSN 0014-5793, 06/2015, Volume 589, Issue 13, pp. 1418 - 1422
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 09/2010, Volume 51, Issue 9, pp. 2611 - 2618
Journal Article