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Natural Product Research, ISSN 1478-6419, 2019, pp. 1 - 9
Two new β-carboline alkaloids, aspergillspins A-B (1-2), three new quinolone alkaloids, aspergillspins C-E (3-5), and two new isocoumarins, aspergillspins F-G... 
β-carboline alkaloid | isocoumarin | quinolone alkaloid | Aspergillussp | Marine-derived fungus
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 01/2020, Volume 30, Issue 2, p. 126810
A series of 1 -1,2,3-triazole/acylhydrazide-tethered tetrahydro- -carboline-4-aminoquinoline conjugates was synthesized with an aim to study their... 
Tetrahydro-β-carboline | Quinoline | Acyl hydrazide | Antiplasmodial | Triazole | POTENT | CHEMISTRY, MEDICINAL | SPIROINDOLONES | RESISTANCE | CHEMISTRY, ORGANIC | BETA-CARBOLINE DERIVATIVES | Tetrahydro-beta-carboline | ANTIMALARIAL
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 11/2019, Volume 181, p. 111567
Mcl-1 is an anti-apoptotic member of Bcl-2 family proteins. The development of inhibitors of Mcl-1 has been challenging. To develop metal-based... 
Copper(II) complex | Mcl-1 | β-Carboline | Anticancer | Apoptosis | MULTIPLE-MYELOMA | DESIGN | CHEMISTRY, MEDICINAL | PROTEIN-PROTEIN INTERACTION | beta-Carboline | FAMILY PROTEINS | RHODIUM(III)-BASED INHIBITOR
Journal Article
Chemistry of Natural Compounds, ISSN 0009-3130, 11/2014, Volume 50, Issue 5, pp. 884 - 888
A new alkaloid, 6-hydroxy-β-carboline-1-carboxylic acid (1), together with six known alkaloids, including β-carboline-1-carboxylic acid (2),... 
canthin-6-one alkaloids | cytotoxic activities | Pharmacy | Picrasma quassioides | β -carboline alkaloids | Plant Sciences | Organic Chemistry | β-carboline alkaloids | BENNET | STEMS | CHEMISTRY, MEDICINAL | beta-carboline alkaloids | CHEMISTRY, ORGANIC | CONSTITUENTS | Phenylalanine | Alkaloids | Saponins
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2011, Volume 52, Issue 25, pp. 3186 - 3188
Two novel alkaloids, trigonoine A containing a 2,8-diazabicyclo[3.3.1]nonane ring system and trigonoine B formed by a combination of a... 
Trigonoine B | Trigonostemon lii | Trigonoine A | β-Carboline alkaloid | CHEMISTRY, ORGANIC | beta-Carboline alkaloid | Tetrahedrons | Alkaloids | Spectroscopy | Nuclear magnetic resonance | Two dimensional
Journal Article
Pesticide Biochemistry and Physiology, ISSN 0048-3575, 02/2019, Volume 154, pp. 67 - 77
The β-carboline alkaloids are a large group of naturally occurring and synthetic indole alkaloids with remarkable pharmacological properties. Furthermore,... 
Autophagy induction | Harmine | β-Carboline alkaloids | PI3K/Akt/mTOR | Sf9 cells | APOPTOSIS | DESIGN | PHYSIOLOGY | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | DEATH | beta-Carboline alkaloids | ENTOMOLOGY | INHIBITION | DERIVATIVES | CONSUMPTION | EXTRACT
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 06/2010, Volume 113, Issue 6, pp. 1659 - 1675
J. Neurochem. (2010) 113, 1659–1675. β‐Carbolines (BCs) are potential endogenous and exogenous neurotoxins that may contribute to the pathogenesis of... 
9‐methyl‐β‐carboline | inflammation | neuroregeneration | neuroprotection | dopaminergic neurons | Dopaminergic neurons | Neuroprotection | Inflammation | 9-methyl-β-carboline | Neuroregeneration | MONOAMINE-OXIDASE | CAMP RESPONSE ELEMENT | MICROGLIAL ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TETRAHYDRO-BETA-CARBOLINE | SUBSTANTIA-NIGRA | NEUROSCIENCES | GATA TRANSCRIPTION FACTORS | TYROSINE-HYDROXYLASE GENE | 9-methyl-beta-carboline | CENTRAL-NERVOUS-SYSTEM | STRIATAL NEURONS | PARKINSONS-DISEASE | L-Lactate Dehydrogenase - metabolism | Tyrosine 3-Monooxygenase - metabolism | Mesencephalon - cytology | Embryo, Mammalian | RNA, Messenger - metabolism | Dose-Response Relationship, Drug | Drug Interactions | Neuroprotective Agents - pharmacology | Statistics, Nonparametric | Female | Deoxyuridine - pharmacology | Neurons - metabolism | Receptors, Cytokine - metabolism | Neurons - drug effects | Cytokines - genetics | Receptors, Cytokine - genetics | Dopamine - metabolism | Cytokines - metabolism | Anti-Inflammatory Agents - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Piperazines - pharmacology | Dopa Decarboxylase - metabolism | Gene Expression Regulation - drug effects | Pregnancy | Regeneration - drug effects | Animals | Deoxyuridine - analogs & derivatives | Lipopolysaccharides - pharmacology | Mice | Carbolines - pharmacology
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2010, Volume 51, Issue 48, pp. 6356 - 6359
-Benzenedisulfonimide catalyzed synthesis of tetrahydroisoquinolines and tetrahydro-β-carbolines. The synthesis of tetrahydroisoquinolines and... 
Brønsted acid | Tetrahydro-β-carbolines | Homogeneous catalysis | 2-Arylethanamines | Tetrahydroisoquinoline | Bronsted acid | 1-ARYL-TETRAHYDROISOQUINOLINE ANALOGS | CHEMISTRY, ORGANIC | CONDENSATION | FACILE | DERIVATIVES | Tetrahydro-beta-carbolines | WATER
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 04/2010, Volume 128, Issue 3, pp. 662 - 671
Ethnopharmacological relevance - Banisteriopsis caapi, a woody vine from the Amazonian basin, is popularly known as an ingredient of a sacred drink ayahuasca,... 
Antioxidants | Monoamine oxidase inhibitors | Banisteriopsis caapi (Spruce ex Griseb.) | β-carboline alkaloids | Proanthocyanidines | HPLC | Parkinson’s disease
Journal Article
Synthetic Communications, ISSN 0039-7911, 04/2007, Volume 37, Issue 8, pp. 1273 - 1280
The first total synthesis of the chlorinated 1-oxo-β-carboline alkaloid bauerine C based on a Japp-Klingemann reaction is reported. An intermediate of this... 
cyclizations | dehydrogenations | 1-oxo-β-carbolines | bauerine | alkaloids | Bauerine | Alkaloids | Cyclizations | Dehydrogenations | TRYPTAMINES | CHEMISTRY, ORGANIC | 1-oxo-beta-carbolines
Journal Article
Journal of Liquid Chromatography & Related Technologies, ISSN 1082-6076, 06/2012, Volume 35, Issue 11, pp. 1597 - 1606
By using a two-phase solvent system composed of n-hexane-ethyl acetate-methanol-water (2:2:2:2, v/v/v/v), a high-speed counter-current chromatography technique... 
3-methylcanthin-2,6-dione | high-speed countercurrent chromatography | Picrasma quassiodes | alkaloids | 1-methoxycarbonyl-β-carboline | 4-methoxy-5-hydroxycanthin-6-one | CHEMISTRY, ANALYTICAL | BIOCHEMICAL RESEARCH METHODS | 1-methoxycarbonyl-beta-carboline | SEPARATION | Picrasma quassiodes (D. Don) Benn
Journal Article
中国化学快报:英文版, ISSN 1001-8417, 2014, Volume 25, Issue 11, pp. 1503 - 1506
Tetrahydro-b-carbolines with strictosamide skeleton have been synthesized via intermolecular condensation, selective reduction, and intramolecular cyclization... 
合成 | 分子间 | 选择性还原 | 色胺 | 邻苯二甲酸酐 | 分子内环化 | 四氢 | 咔啉 | Tetrahydro-β-carboline | Strictosamide | Tryptamine | Phthalic anhydride | CYCLIZATIONS | CONDENSATION | Tetrahydro-beta-carboline | INDOLE ALKALOIDS | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 2007, Volume 15, Issue 22, pp. 6909 - 6919
In this study, a new class of phenolic tetrahydro-β-carboline RGD peptidomimetic conjugates was designed and synthesized. The radical scavenging activities of... 
Antithrombotic agent | Dual-acting agents | Phenolic tetrahydro-β-carboline RGD peptidomimetics conjugates | Free radicals scavenger | phenolic tetrahydro-beta-carboline RGD | antithrombotic agent | OXIDATIVE STRESS | CHEMISTRY, MEDICINAL | ENDOTHELIAL DYSFUNCTION | ANTIOXIDANTS | SOLID-PHASE SYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MYOCARDIAL-ISCHEMIA-REPERFUSION | CHEMISTRY, ORGANIC | peptidomimetics conjugates | INFARCT SIZE | AMINO-ACIDS | NITRIC-OXIDE | free radicals scavenger | FREE-RADICAL SCAVENGERS | dual-acting agents | BIOLOGICAL-SYSTEMS | Free Radical Scavengers - pharmacology | Fibrinolytic Agents - chemistry | Free Radical Scavengers - chemistry | PC12 Cells | Dose-Response Relationship, Drug | Platelet Aggregation Inhibitors - chemical synthesis | Carbolines - chemistry | Drug Design | Phenol - chemistry | Free Radical Scavengers - chemical synthesis | Platelet Aggregation Inhibitors - pharmacology | Fibrinolytic Agents - chemical synthesis | Molecular Structure | Platelet Aggregation - drug effects | Thrombosis - prevention & control | Oligopeptides - chemistry | Disease Models, Animal | Carbolines - chemical synthesis | Cell Survival - drug effects | Oligopeptides - chemical synthesis | Rats | Fibrinolytic Agents - pharmacology | Animals | Platelet Aggregation Inhibitors - chemistry | Thrombosis - drug therapy | Oligopeptides - pharmacology | Organic chemistry | Chemical Sciences
Journal Article
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