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Free Radical Biology and Medicine, ISSN 0891-5849, 07/2017, Volume 108, pp. S73 - S73
Journal Article
Journal of Nuclear Medicine, ISSN 0161-5505, 08/2018, Volume 59, Issue 8, pp. 1249 - 1254
Journal Article
Gene, ISSN 0378-1119, 04/2019, Volume 691, pp. 8 - 17
In human pancreatic β-cells, oxidative stress and cellular injures can be induced by H O treatment. The KEAP1/NRF2 axis is a key antioxidant signaling pathway.... 
NRF2 | Pancreatic β-cell | KEAP1 | Apoptosis
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 07/2017, Volume 108, pp. S71 - S71
Journal Article
11/2011
Type 1 and type 2 diabetes are characterized by an excessive loss of insulin producing β-cells. β-cells are particularly susceptible to increased oxidative... 
toxicity | Oxidative stress | Peroxiredoxin 2 | 0719 | β-cell
Dissertation
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2007, Volume 104, Issue 4, pp. 1348 - 1353
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 07/2019, Volume 234, Issue 7, pp. 11047 - 11059
New onset of diabetes is associated with the use of statins. We have recently demonstrated that pravastatin-treated hypercholesterolemic LDL receptor knockout... 
β cell | cell death | insulin | statins | coenzyme Q
Journal Article
06/2011
R-spondin-1 (Rspo1) is an intestinal growth factor known to exert its effects through activation of the canonical Wnt (cWnt) pathway, but its function in the... 
R-spondin-1 | 0719 | Proliferation | Islet | β-cell | Apoptosis | Insulin secretion
Dissertation
Current Diabetes Reviews, ISSN 1573-3998, 2013, Volume 9, Issue 1, pp. 25 - 53
Journal Article
Journal of Nuclear Medicine, ISSN 0161-5505, 8/2018, Volume 59, Issue 8, pp. 1249 - 1254
Type 1 diabetes mellitus (T1DM) is characterized by a loss of β-cells in the islets of Langerhans of the pancreas and subsequent deficient insulin secretion in... 
β-cell mass | PHNO | diabetes | pancreas | Endocrinology | PET
Journal Article
07/2013
In a previous study, we observed that multiple low doses of streptozotocin (STZ) can induce spontaneous restoration of normoglycemia in adult mouse diabetes... 
Blood glucose | Mouse | Streptozotocin | β cell mass | Type 1 diabetes mellitus
Web Resource
Molecular and Cellular Endocrinology, ISSN 0303-7207, 10/2015, Volume 414, pp. 111 - 119
Diabetes mellitus is a leading cause of death and disability worldwide, which presents a serious public health crisis in China nowadays. It has been well... 
1, 25-Dihydroxyvitamin D3 | β-Cell apoptosis | Diabetes mellitus | MTOR
Journal Article
Diabetes & metabolism, ISSN 1262-3636, 01/2019
Journal Article
Endocrine Journal, ISSN 0918-8959, 2017
We investigated whether glucotoxicity of β-cell function could be eliminated after medical nutrition therapy (MNT) without forced correction of hyperglycemia... 
Medical nutrition therapy | β-cell function | Glucotoxicity
Journal Article
Endocrine Journal, ISSN 0918-8959, 2017
To understand metformin's effects on fibroblast growth factors (FGFs) and fibroblast growth factor receptor 1 (FGFR1), we investigated circulating fibroblast... 
β cell | Diabetes | Visceral adipose | FGF21 | FGFR1
Journal Article
Endocrine Journal, ISSN 0918-8959, 2017
Recent studies have suggested that decreased pancreatic β-cell function and mass are common features of patients with type 2 diabetes mellitus. Pancreatic... 
β cell | Islets | Diabetes | p62 | Sequestosome 1
Journal Article
Life Sciences, ISSN 0024-3205, 10/2019, Volume 235, p. 116858
The current study was conducted to investigate the potential protective effects of hesperidin and its possible mechanisms of action on pancreatic β-cells in... 
ER stress | Oxidative stress | Diabetes | Pancreatic β-cell | Hesperidin
Journal Article
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 03/2013, Volume 304, Issue 6, pp. 557 - 565
c-Kit and its ligand stem cell factor (SCF) are important for β-cell survival and maturation; meanwhile, interactions between the Fas receptor (Fas) and Fas... 
fas | β-cell apoptosis | Diabetes | c-Kit | Insulin secretion
Journal Article
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